Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research.
Only by dissecting the molecular mechanisms that trigger and advance diseases and dysfunctions can we design effective treatments and medicines. The Research Master's in Molecular Mechanisms of Disease (MMD) offers you an intensive two-year programme that provides you with in-depth knowledge and research experience of disease-related molecular mechanisms. In addition, you will acquire skills such as academic writing and presentation skills and learn how to successfully apply for grants and market yourself.
As an MMD student you will be part of the unique research community that is found within the Radboud Institute for Molecular Life Sciences (RIMLS). Like you, RIMLS researchers have a strong passion for research. They will assist you throughout the programme with guidance and expertise, supporting you in acquiring knowledge and developing excellent research skills. The RIMLS is one of the research institutes of the Radboud university medical center, so their research is closely linked to the clinic and thus aimed at translating results into treatments for patients. Examples include the translation of insights into the biology of antigen-presenting cells into new immunological cancer therapies and understanding the mutations underlying blindness into the development of gene therapies for patients with inherited blindness.
See the website http://www.ru.nl/masters/mmd
- You will follow a broad biomedical programme that allows you to specialise in your specific field-of-interest.
- You will have intense daily contact with established researchers.
- You will participate in group-oriented education and be part of a small group of highly motivated national and international students.
- A personal mentor will help you to reflect on your study programme and career perspective.
- You will do two 6-months research internships one of which will be abroad.
- There is a 92% pass rate of MMD students within the two years.
- International MMD students can apply for scholarships from the Radboudumc Study Fund.
There is considerable demand for experts in the molecular biomedical sciences as well as in their application to the development of treatments for diseases such as cancer, autoimmune and inflammatory disorders, and metabolic diseases.
Graduates in MMD are equipped with cutting-edge knowledge of multidisciplinary research in the mechanisms of disease and in state-of-the-art diagnostic methods and technologies. During the programme, you will develop a highly critical, independent approach to problem-solving. You will also acquire the basic management skills needed to lead R&D projects in the biotechnology and pharmaceutical industries.
Most of our graduates will enter an international PhD programme to continue with research in academia or industry.
The MSc Molecular Mechanisms of Disease aims to provide all skills and knowledge necessary to rapidly enter an international PhD programme. In the Netherlands and many places in Europe, it is impossible to start a PhD programme directly after obtaining a Bachelor's degree. This research Master’s programme seriously increases your chances for obtaining an excellent PhD training position by giving you a mature perspective and a broad range of experimental approaches. In fact, over 90% of our graduates has started a (funded) PhD project.
The Radboud Institute for Molecular Life Sciences (RIMLS) recruits about fifty PhD students a year. MMD graduates are excellent candidates for these positions. Furthermore, the Radboud university medical centre offers the opportunity for its research-oriented Master's students to write their own research project. The best candidates are awarded a fully funded four-year PhD studentship at the department of their choice.
The molecular regulation of cellular processes is crucial for human development, and maintenance of health throughout life. It's evident that cellular malfunction is the cause of common multi-factorial diseases such as diabetes, immune and inflammatory disorders, renal disease, cardiovascular, metabolic and neurodegenerative diseases as well as obesity and cancer.
The Radboud Institute for Molecular Life Sciences (RIMLS) Graduate School plays a key role in developing new therapies for the fight against such diseases. RIMLS aims to improve diagnostics and develop new treatments by generating basic knowledge in the molecular biomedical life sciences and translating it into clinical application and experimental research in patients.
The RIMLS – which is part of Radboud university medical center – offers an exclusive Master's programme in Molecular Mechanisms of Disease. Top researchers and clinicians teach the programme.
The MMD programme is organised along three major educational themes which reflect the main research areas present in the RIMLS and which each include both a fundamental and a disease-related aspect:
- Theme 1 Infection, Immunity and Regenerative Medicine / Immunity-related Disorders and Immunotherapy
- Theme 2 Metabolism, Transport and Motion / Metabolic Disorders
- Theme 3 Cell Growth and Differentiation / Developmental Disorders and Malignancies
See the website http://www.ru.nl/masters/mmd
This award is offered within the Postgraduate Scheme in Health Technology, which aims to provide professionals in Medical Imaging, Radiotherapy, Medical Laboratory Science, Health Technology, as well as others interested in health technology, with an opportunity to develop advanced levels of knowledge and skills.
A. Advancement in Knowledge and Skill
Students develop intellectually, professionally and personally while advancing their knowledge and skills in Medical Laboratory Science. The specific aims of this award are:
B. Professional Development
C. Evidence-based Practice
D. Personal Development
Our laboratories are well-equipped to support students in their studies, research and dissertations. Our specialised equipment includes a flow cytometer, cell culture facilities; basic and advanced instruments for molecular biology research (including thermal cyclers, DNA sequencers, real-time PCR systems and an automatic mutation detection system), microplate systems for ELISA work, HPLC, FPLC, tissue processors, automatic cell analysers, a preparative ultracentrifuge and an automated biochemical analyser.
This programme is accredited by the Institute of Biomedical Science (UK), and graduates are eligible to apply for Membership of the Institute.
To be eligible for the MSc in Medical Laboratory Science (MScMLS), students are required to complete 30 credits:
Apart from the award of MScMLS, students can choose to graduate with the following specialism:
To be eligible for the specialism, students should complete 2 Compulsory Subjects (6 credits), a Dissertation (9 credits) related to the specialism, 4 Specialty Subjects (12 credits) and 1 Elective Subject (3 credits).
* Specialty Subject
This MRes Molecular Microbiology course will provide you with a strong grounding in microbial genetics and molecular biology, through the exploration of microbial structure, physiology, and behaviour at the molecular level. The course includes optional modules for you to select depending upon your aspirations and interests.
The MRes courses are divided into a taught element (60 credit points) and a laboratory-based research project (120 credit points). You will complete the extended research project in one of our highly rated research teams.
This exciting MSc Molecular Microbiology course is designed to provide you with a multidisciplinary approach to the study of the molecular biology of micro-organisms. You'll study the key concepts associated with molecular microbiology and use these when considering their role in health, disease and in the natural environment.
Practical work forms a large proportion of your learning to ensure that you have extensive skills for employment or research and there is an emphasis on developing knowledge and understanding such that you acquire the skills, qualities and attributes expected by employers or for postgraduate research.
The MSc is divided into 60 credit point taught modules and the research project is worth 60 credit points.
Visit us on campus throughout the year, find and register for our next open event on http://www.ntu.ac.uk/pgevents.
Postgraduate Loans are now Open for Home/EU students - https://www.gov.uk/postgraduate-loan/how-to-apply
Scholarships & Discounts available
Molecular biology and genomics play an increasingly important and exciting role in research on medically important parasites and arthropods, and this award provides advanced training in this field. It provides an important foundation of knowledge of the basic biology of parasites and vectors, followed by specialised modules on the molecular and cellular biology and functional genomics of parasites and vectors, as well as related public health, and tropical health issues. There is a significant practical component throughout the programme, and the laboratory work undertaken provides a wide range of techniques that would be highly relevant to a future research career. Following the taught component, participants complete a dissertation including a period of applied research either overseas or in Liverpool.
LSTM education courses are taught within a dynamic environment by staff working at the cutting-edge of research in tropical medicine and global health. They are designed to enable the professional development of the student, to be relevant to students from both the UK and overseas and to promote approaches to study that will enable students to continue their learning into the future.
This course aims to:
Equip students with the knowledge and practical skills to develop a career in molecular research in parasitology or vector biology.
Provide practical experience of a range of specialised technical and analytical skills relevant to the study of the molecular biology of parasites and disease vectors.
Enable students to conduct independent research in the laboratory and/or field.
Produce graduates who are experienced, committed, informed, proactive and effective professionals, capable of taking substantial and leading professional roles.
Facilitate high quality learning that is informed by critical analysis of current research.
Develop independent and reflective approaches to study that will enable graduates to continue to learn in the future.
Many alumni of LSTM hold prominent positions in health ministries, universities, hospitals, and international organisations throughout the world. Graduates are competitively placed to begin PhD programmes, seek employment as research assistants, work in developing countries with a wide variety of employers, or return to previous employers with enhanced knowledge and skills with which to advance their existing careers. Graduates of the MSc Molecular Biology of Parasites and Disease Vectors have undergone excellent general preparation for a career in laboratory research in biological sciences, in which molecular biology is widely applied, and are particularly well placed for careers in research or training in areas related to the molecular biology of parasitic and vector-borne tropical diseases.
Professor Mark Taylor "Parasitology at LSTM studies how best to treat and control parasitic diseases such as malaria and the Neglected Tropical Diseases. We cover the entire spectrum of translational research from the discovery of new drugs, vaccines and diagnostics through to large scale global programmes aimed at eliminating diseases such as elephantiasis and river blindness. In addition to the traditional parasites and their vectors, we also work on other important tropical diseases such as snakebite, arboviruses, and tuberculosis."
The practice of medicine, especially in the disciplines of Pathology and Genetics is increasingly reliant on Genomic technology. The aim of this programme is to increase the knowledge and capability of scientific and clinical staff using genetic data in their daily work allowing them to engage confidently with the scientific concepts of Molecular Pathology and Genomic Medicine, and to use their skills to improve patient care. The programme could also provide a foundation for those students interested in developing a clinical academic career.
The University of Edinburgh is at the forefront of Genomic Technology. To adequately realise the potential of these technologies in a diagnostic setting this programme will cover the scientific underpinning and clinical application of genomic technology to enable clinicians and scientists to provide maximum benefit to patients.
The programme will provide a structured environment for students wishing to develop cutting edge knowledge and practical skills in Clinical Genomics and Molecular Pathology. The programme structure is designed around three central themes: scientific foundation, diagnostics, and patient management and treatment.
The PG Cert is comprised of four compulsory courses, totalling 60 credits.
Students will learn via a mixture of guided online activities, in-person tutorials, and in course four, an extended project. In addition to structured learning, students are expected to conduct independent study and read around the subject area.
Students will develop their critical analysis skills through evaluation of primary research articles and reviews. Students will learn how to perform variant analysis and next generation sequencing data analysis using relevant bioinformatics tools. Students can also expect to develop the communication skills required for interacting with the major stakeholders of genomic information: clinical scientists, doctors and patients.
Teaching is performed by a variety of staff who are leaders in their field, as well as experienced educators. The core teaching team is comprised of staff from the NHS Lothian Clinical Genetics Service and Pathology departments. Additional teaching is performed by clinical and scientific staff from across Edinburgh University and the UK. In addition, the programme has a dedicated teaching teaching fellow, who will provide academic and pastoral support throughout all courses.
Postgraduate Professional Development (PPD)
Aimed at working professionals who want to advance their knowledge through a postgraduate-level course(s), without the time or financial commitment of a full Postgraduate Certificate.
You may take a maximum of 50 credits worth of courses over two years through our PPD scheme. These lead to a University of Edinburgh postgraduate award of academic credit. Alternatively, after one year of taking courses you can choose to transfer your credits and continue on to studying towards a higher award on the Postgraduate Certificate programme. Any time spent studying PPD will be deducted from the amount of time you will have left to complete a Postgraduate Certificate programme.
The programme will adopt a blended learning format, with teaching delivered via online as a eLectures and interviews, in-person tutorials, and online interactive content.
Programme materials and resources will all be available in the virtual learning environment, Learn. Learn provides an interactive forum for students to engage with other learners and the programme teaching staff. Multiple feedback opportunities will be integrated within each course and will comprise of weekly interactive online quizzes, discussion boards and office hours. In-person tutorials will also represent an important feedback opportunity for students. Assessment will vary slightly with each course, common assessment modalities include structured written assignments, presentations and data analysis reports.
The programme is aimed primarily at NHS laboratory and clinical staff. It is designed for anyone wishing to expand their understanding of molecular pathology and how it applies to clinical diagnostics. The PG Cert will be of use to a wide range of individuals as it can be used to support FRC Path, Clinical Scientist Development and Genetic Technologist Registration. It can be used as a component of STP and could potentially contribute the first 60 credits of MSc. It will also provide the scientific underpinning for Genetic Counselling.
Whether you are a new graduate or already employed and seeking to further your career prospects, this course offers a solid career development path. You can also choose this course if you wish to pursue research in biotechnology at PhD level.
Biotechnology is the application of biological processes and is underpinned by • cell biology • molecular biology • bioinformatics • structural biology. It encompasses a wide range of technologies for modifying living organisms or their products according to human needs.
Applications of biotechnology span medicine, technology and engineering.
Important biotechnological advances including
The course is led by academics who are actively involved in biotechnology research and its application to the manipulation of proteins, DNA, mammalian cells and plants. Staff also have expertise in the use of nanoparticles in drug delivery and the manipulation of microbes in industrial and environmental biotechnology.
You are supported throughout your studies by an academic advisor who will help you develop your study and personal skills.
What is biotechnology
Biotechnology is the basis for the production of current leading biopharmaceuticals and has already provided us with the 'clot-busting' drug, tissue plasminogen activator for the treatment of thrombosis and myocardial infarction. It also holds the promise of new treatments for neurodegeneration and cancer through recombinant antibodies.
Genetically modified plants have improved crop yields and are able to grow in a changing environment. Manipulation of cellular organisms through gene editing methods have also yielded a greater understanding of many disease states and have allowed us to understand how life itself functions.
You begin your studies focusing on the fundamentals of advanced cell biology and molecular biology before specialising in both molecular and plant biotechnology. Practical skills are developed throughout the course and you gain experience in molecular biology techniques such as PCR and sub cloning alongside tissue culture.
Core to the program is the practical module where you gain experience in a range of techniques used in the determination of transcription and translational levels, for example.
All practicals are supported by experienced academic staff, skilled in the latest biotechnological techniques.
Research and statistical skills are developed throughout the program. Towards the end of the program you apply your skills on a two month research project into a current biotechnological application. Employability skills are developed throughout the course in two modules.
The masters (MSc) award is achieved by successfully completing 180 credits.
The postgraduate certificate (PgCert) is achieved by successfully completing 60 credits.
The postgraduate diploma (PgDip) is achieved by successfully completing 120 credits.
Optional modules :
As students progress through the course they are exposed to a wide range of teaching and learning activities. The assessment strategy of the postgraduate course considers diverse assessment methods. Some modules offer dedicated formative feedback to aid skills development with assessments going through several rounds of formative tutor and peer feedback. Summative assessment methods are diverse, with examinations present in theory-based modules to test independent knowledge and data analysis. Several modules are entirely coursework-based, with a portfolio of skills such laboratory practical's and research proposals generated throughout the course forming the summative tasks. In all cases, the assessment criteria for all assessed assignments are made available to student prior to submission.
The course is suitable for people wishing to develop their knowledge of molecular and cell biotechnology and its application to solving health and industrial problems.
You can find career opportunities in areas such as
Students on this course have gone on to roles including experimental officers in contract research, research and development in scientists, diagnostics specialists and applications specialists. Many of our graduates also go on to study for PhDs and continue as academic lecturers.