The MSc in Biotherapeutics educates students on the practical uses of molecular advances in the discovery of protein and other biomolecular drug candidates and their development into biotherapeutics. It will provide students with a comprehensive understanding of the development of biotherapeutics, beginning with pre-clinical modelling and target identification together with antibody engineering, biochemical and biophysical characterisation, and development issues for bioprocessing. Systems biology of biotechnological processes and approaches to the analysis of proteomics-based discovery data will be covered in detail together with mathematical modelling, bioinformatics analysis and data integration strategies. Regulatory issues, and innovation and commercialisation strategies, will also be covered. Mammalian cell culture and bioprocess laboratory structure will be comprehensively covered in addition to novel approaches to therapeutic development. A practical drug discovery laboratory project will form a significant component of the experience of how candidates are identified and brought through the development pipeline.
This programme is the culmination of close collaboration between the UCD School of Biomolecular and Biomedical Science, Systems Biology Ireland and the Biopharmaceutical Industry in Ireland and across the world.
Course Content and Structure
The structure of the programme is as follows:
Semester 1 • Biotherapeutic Discovery and Development I • Professional Career Development • Recombinant DNA Technology • Business of Biotechnology & Science • Biomedical Diagnostics • High Content Screening Microscopy • Pharmacology & Drug Development
Semesters 2 & 3 • Biotherapeutic Discovery and Development II • Systems Biology in Drug Development • Professional Career Development • Bioprocessing Laboratory • Emerging Issues in Biotechnology • Regulatory Affairs • Microbial & Animal Cell Products • Project – Biotherapeutic Development
This advanced graduate degree in Biotherapeutics has been developed in consultation with the Biopharmaceutical industry and is recognised and valued by them. A key feature is the undertaking of a significant drug discovery and development laboratory project which is reviewed by industry partners. This engagement is designed to help graduates identify opportunities in the industry at the earliest stage. Prospective employers include: Novartis, Glaxo SmithKline, Eli Lilly, Johnson & Johnson, Pfizer, Janssen Biologics, AstraZeneca, MSD, Bristol Myers Squibb, Abbott, Sanofi.
Facilities and Resources
Students on this programme will benefit from the use of a research skills laboratory in the prestigious UCD Conway Institute, as well as state-of-the-art teaching and laboratory facilities in the new O'Brien Centre for Science.
This programme is intended for applicants who have an upper second class honours degree, or the international equivalent, in a biological or chemical science. This includes a BSc in Biotechnology, Biochemistry, Microbiology, Genetics, Neuroscience, Physiology, Pharmacology, Medicinal Chemistry or an equivalent qualification. Applicants whose first language is not English must also demonstrate English language proficiency of IELTS 6.5 (no band less than 6.0 in each element), or equivalent.
Recipient: University College Dublin
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