Applications are invited for a 12 month Masters thesis at the Institute of Molecular Pathology (IMP) in Vienna in the laboratory of Dr David Keays focused on cortical development. The human cortex is arguably the most complex structure on the planet comprised of more than 85 billion neurons, and in excess of 100 trillion synapses. Its formation is dependent on three key cellular processes: (1) the generation of neurons; (2) the migration of neurons; and finally (3) the differential of neurons. This project will focus on the role of vesicular trafficking in neuronal migration and neurodevelopmental diseases. The project will exploit a number of new mouse models that have been generated in the Keays lab that recapitulate human mutations identified by whole exome sequencing.
The successful applicant will gain experience in mouse genetics, molecular biology, cellular assays, and histological techniques. He/she will join a young dynamic team, and is expected to be passionate, hard working, and creative. The start date is flexible and the successful applicant will receive a monthly stipend.
Previous experience in the field of Neuroscience will be advantageous.
Applications with a covering letter and CV should be sent to: