Masters Degrees in Medical Genetics, United Kingdom

The increasing impact of genetics in healthcare and the development of newer sophisticated technologies requires contributions from research scientists, clinical laboratory scientists and clinicians to investigate the causes of, and therefore permit optimal management for, diseases for which alterations in the genome, either at the DNA sequence level or epigenetic level, play a significant role. Collaboration between staff from the University of Glasgow and the NHS West of Scotland Genetics Service enables the MSc in Medical Genetics and Genomics to provide a state-of-the-art view of the application of modern genetic and genomic technologies in medical genetics research and diagnostics, and in delivery of a high quality genetics service to patients, as well as in design of targeted therapies.

Why this programme

◾This is a fully up-to-date Medical Genetics degree delivered by dedicated, multi-award-winning teaching and clinical staff of the University, with considerable input from hospital-based Regional Genetics Service clinicians and clinical scientists.
◾The full spectrum of genetic services is represented, from patient and family counselling to diagnostic testing of individuals and screening of entire populations for genetic conditions: eg the NHS prenatal and newborn screening programmes.
◾The MSc Medical Genetics Course is based on the south side of the River Clyde in the brand new (2015) purpose built Teaching & Learning Centre, at the Queen Elizabeth University Hospitals (we are located 4 miles from the main University Campus). The Centre also houses state of the art educational resources, including a purpose built teaching laboratory, computing facilities and a well equipped library. The West of Scotland Genetic Services are also based here at the Queen Elizabeth Campus allowing students to learn directly from NHS staff about the latest developments to this service.
◾The Medical Genetics MSc Teaching Staff have won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering). These awards recognise and reward excellence and good practice in postgraduate education.
◾The close collaboration between university and hospital staff ensures that the Medical Genetics MSc provides a completely up-to-date representation of the practice of medical genetics and you will have the opportunity to observe during clinics and visit the diagnostic laboratories at the new Southern General Hospital laboratory medicine building.
◾The Medical Genetics degree explores the effects of mutations and variants as well as the current techniques used in NHS genetics laboratory diagnostics and recent developments in diagnostics (including microarray analysis and the use of massively parallel [“next-generation”] sequencing).
◾New developments in medical genetics are incorporated into the lectures and interactive teaching sessions very soon after they are presented at international meetings or published, and you will gain hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenesis of DNA sequence variants.
◾You will develop your skills in problem solving, experimental design, evaluation and interpretation of experimental data, literature searches, scientific writing, oral presentations, poster presentations and team working.
◾This MSc programme will lay the academic foundations on which some students may build in pursuing research at PhD level in genetics or related areas of biomedical science or by moving into related careers in diagnostic services.
◾The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.
◾For doctors: The Joint Royal Colleges of Physicians’ Training Board (JRCPTB) in the UK recognises the MSc in Medical Genetics and Genomics (which was established in 1984) as counting for six months of the higher specialist training in Clinical Genetics.
◾The Medical Council of Hong Kong recognises the MSc in Medical Genetics and Genomics from University of Glasgow in it's list of Quotable Qualifications.

Programme structure

Genetic Disease: from the Laboratory to the Clinic

This course is designed in collaboration with the West of Scotland Regional Genetics Service to give students a working knowledge of the principles and practice of Medical Genetics and Genomics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease. The link from genotype to phenotype, will be explored, with consideration of how this knowledge might contribute to new therapeutic approaches.

Case Investigations in Medical Genetics and Genomics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Clinical Genomics

Students will take this course OR Omic Technologies for Biomedical Sciences OR Frontiers in Cancer Science.

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussion the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Omic technologies for the Biomedical Sciences: from Genomics to Metabolomics

Students will take this course OR Clinical Genomics OR Frontiers in Cancer Science.

Visit the website for further information

Career prospects

Research: About half of our graduates enter a research career and most of these graduates undertake and complete PhDs; the MSc in Medical Genetics and Genomics facilitates acquisition of skills relevant to a career in research in many different bio-molecular disciplines.

Diagnostics: Some of our graduates enter careers with clinical genetic diagnostic services, particularly in molecular genetics and cytogenetics.

Clinical genetics: Those of our graduates with a prior medical / nursing training often utilise their new skills in careers as clinical geneticists or genetic counsellors.

Other: Although the focus of teaching is on using the available technologies for the purpose of genetic diagnostics, many of these technologies are used in diverse areas of biomedical science research and in forensic DNA analysis. Some of our numerous graduates, who are now employed in many countries around the world, have entered careers in industry, scientific publishing, education and medicine.

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The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents.

About this degree

The programme provides a thorough grounding in modern approaches to the understanding of the genetics of disease alongside the cutting-edge research methods and techniques used to advance our understanding of development of disease. Core modules provide a broad coverage of the genetics of disease, research skills and social aspects, whilst specialised streams in Inherited Diseases, Pharmacogenetics and Computational Genomics, in which students can qualify, and the research project allow more in-depth analysis in areas of genetics.

Students undertake modules to the value of 180 credits.

The programme consists of four core modules (60 credits) and two specialist modules (30 credits) and a research project culminating in a dissertation (90 credits).

A Postgraduate Diploma consisting of six modules (four core modules in term one and two modules within the selected stream in term two) is offered, full-time nine months.

A Postgraduate Certificate consisting of four core modules in term one (60 credits) is offered, full-time three months.

Core modules

• Advanced Human Genetics: Research Principles
• Understanding Bioinformatics Resources and their Applications
• Human Genetics: Core Skills
• Basic Statistics for Medical Sciences

Specialist modules

In term two you will take specialist modules depending on the specialist stream you select: Inherited Disease (A); Pharmacogenetics (B); Computational Genomics (C). 

• Applications in Human Genetics (A)
• Either Genetics of Cardiovascular Disease or Genetics of Neurological Disease (A)
• Clinical Applications of Pharmacogenetic Tests (B)
• Anti-Cancer Personalised Medicine or Pharmacogenomics, adverse drug reactions and biomarkers (B)
• Applications in Human Genetics (C)
• Statistics for Interpreting Genetic Data (C)

Dissertation/report

Students undertake an original research project investigating topical questions in genetics and genetics of human disease which culminates in a dissertation of 12,000 to 14,000 words and an oral presentation.

Teaching and learning

Students develop their knowledge and understanding of genetics of human diseases through a combination of lectures, seminars, tutorials, presentations and journal clubs. Taught modules are assessed by unseen written examination and/or, written reports, oral presentations and coursework. The research project is assessed by the dissertation and oral presentation. 

Further information on modules and degree structure available on the UCL Genetics Institute website.

Further information on modules and degree structure is available on the department website: Genetics of Human Disease MSc

Careers

Advanced training in genetic techniques including bioinformatic and statistical approaches positions graduates well for PhD studentships in laboratories using genetic techniques to examine diseases such as heart disease, cancer and neurological disorders. Another large group will seek research jobs in the pharmaceutical industry, or jobs related to genetics in healthcare organisations.

Recent career destinations for this degree

• Laboratory Specialist, King Abdullah Medical Complex
• Non-Clinical Research Associate, University of Oxford
• Trainee Geneticist, Oxford University Hospitals NHS Trust
• PhD in Cardiovascular Science, UCL
• Genomic Research Technician, Genome Centre

Employability

The MSc in Genetics of Human Disease facilitates acquisition of knowledge and skills relevant to a career in research in many different biomedical disciplines. About half of our graduates enter a research career by undertaking and completing PhDs and working as research associates/scientists in academia. Some of our graduates go on to jobs in the pharmaceutical industry, while others enter careers with clinical genetic diagnosis services, particularly in molecular genetics, in healthcare organisations and hospitals around the world. Those graduates with a prior medical training often utilise their new skills as clinical geneticists.

Careers data is taken from the ‘Destinations of Leavers from Higher Education’ survey undertaken by HESA looking at the destinations of UK and EU students in the 2013–2015 graduating cohorts six months after graduation.

Why study this degree at UCL?

UCL is in a unique position to offer both the basic science and application of modern genetics to improve human health. The programme is a cross-faculty initiative with teaching from across the School of Life and Medical Sciences (SLMS) at UCL.

Students will be based at the UCL Genetics Institute (UGI), a world-leading centre which develops and applies biostatistical and bioinformatic approaches to human and population genetics. Opportunities to conduct laboratory or computational-based research projects are available in the laboratories of world-leading geneticists affiliated to the UGI.

Research Excellence Framework (REF)

The Research Excellence Framework, or REF, is the system for assessing the quality of research in UK higher education institutions. The 2014 REF was carried out by the UK's higher education funding bodies, and the results used to allocate research funding from 2015/16.

The following REF score was awarded to the department: Division of Biosciences

82% rated 4* (‘world-leading’) or 3* (‘internationally excellent’)

Learn more about the scope of UCL's research, and browse case studies, on our Research Impact website.

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The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Research areas include: genetic medicine, developmental genetics, neuromuscular and neurological genetics, mitochondrial genetics and cardiovascular genetics.

As a research postgraduate in the Institute of Genetic Medicine you will be a member of our thriving research community. The Institute is located in Newcastle’s Life Science Centre. You will work alongside a number of research, clinical and educational organisations, including the Northern Genetics Service.

We offer supervision for MPhil in the following research areas:

Cancer genetics and genome instability

Our research includes:
-A major clinical trial for chemoprevention of colon cancer
-Genetic analyses of neuroblastoma susceptibility
-Research into Wilms Tumour (a childhood kidney cancer)
-Studies on cell cycle regulation and genome instability

Cardiovascular genetics and development

We use techniques of high-throughput genetic analyses to identify mechanisms where genetic variability between individuals contributes to the risk of developing cardiovascular disease. We also use mouse, zebrafish and stem cell models to understand the ways in which particular gene families' genetic and environmental factors are involved in the normal and abnormal development of the heart and blood vessels.

Complex disease and quantitative genetics

We work on large-scale studies into the genetic basis of common diseases with complex genetic causes, for example autoimmune disease, complex cardiovascular traits and renal disorders. We are also developing novel statistical methods and tools for analysing this genetic data.

Developmental genetics

We study genes known (or suspected to be) involved in malformations found in newborn babies. These include genes involved in normal and abnormal development of the face, brain, heart, muscle and kidney system. Our research includes the use of knockout mice and zebrafish as laboratory models.

Gene expression and regulation in normal development and disease

We research how gene expression is controlled during development and misregulated in diseases, including the roles of transcription factors, RNA binding proteins and the signalling pathways that control these. We conduct studies of early human brain development, including gene expression analysis, primary cell culture models, and 3D visualisation and modelling.

Genetics of neurological disorders

Our research includes:
-The identification of genes that in isolation can cause neurological disorders
-Molecular mechanisms and treatment of neurometabolic disease
-Complex genetics of common neurological disorders including Parkinson's disease and Alzheimer's disease
-The genetics of epilepsy

Kidney genetics and development

Kidney research focuses on:
-Atypical haemolytic uraemic syndrome (aHUS)
-Vesicoureteric reflux (VUR)
-Cystic renal disease
-Nephrolithiasis to study renal genetics

The discovery that aHUS is a disease of complement dysregulation has led to a specific interest in complement genetics.

Mitochondrial disease

Our research includes:
-Investigation of the role of mitochondria in human disease
-Nuclear-mitochondrial interactions in disease
-The inheritance of mitochondrial DNA heteroplasmy
-Mitochondrial function in stem cells

Neuromuscular genetics

The Neuromuscular Research Group has a series of basic research programmes looking at the function of novel muscle proteins and their roles in pathogenesis. Recently developed translational research programmes are seeking therapeutic targets for various muscle diseases.

Stem cell biology

We research human embryonic stem (ES) cells, germline stem cells and somatic stem cells. ES cell research is aimed at understanding stem cell pluripotency, self-renewal, survival and epigenetic control of differentiation and development. This includes the functional analysis of genes involved in germline stem cell proliferation and differentiation. Somatic stem cell projects include programmes on umbilical cord blood stem cells, haematopoietic progenitors, and limbal stem cells.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.

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Medical Molecular Biology is the application of modern molecular biology and genetics in medical research, medical sciences and the clinic has led to huge advances in the understanding, diagnosis and treatment of human disease. Students choosing to study the Medical Molecular Biology with Genetics program will enjoy a modular, but highly integrated course that delivers the theoretical knowledge and extensive practical laboratory experience required for progress on to PhD studies in medical molecular research and/or employment in molecular diagnostics or medical sciences industries.

Successful graduates will also have attained transferable skills required to independently adapt and optimize scientific methodologies, critically interpret and evaluate self-generated and published scientific literature and data and undertake a predominantly self-reliant approach to laboratory based work, study and research.

Modules:

Research Skills
Medical Biotechnology
Human Molecular Genetics
Human Immunology & Disease
Laboratory Molecular Research
Stem Cells, Disease & Therapy
Applied Anatomy & Histopathology
Research projects are run in the Robert Edwards laboratory and the laboratories of the North West Cancer Research Institute.

Semester 3 consists of a 60-credit laboratory based research project and dissertation.

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The advent of affordable rapid genome sequencing will produce enormous amounts of genetic data on both individuals and populations, and the challenge for scientists is to unlock the potential of this ‘big data’. Doing so requires a new generation of scientists who can combine genetics and bioinformatics to understand how genomic changes cause diseases such as cancer, thus enabling the development of novel treatments, through drugs and gene therapy, and prevention strategies. With the huge expansion in number of individual genomes being sequenced, this is one of the fastest growing areas of biomedical science as we embrace the era of personalised medicine.

See the website http://www.brookes.ac.uk/Courses/Postgraduate/Medical-Genetics-and-Genomics/

Why choose this course?

- This is a 12 month full-time course, with part-time places available.

- Aimed at graduates (UK/ EU, International) wishing to develop skills and knowledge in human genetics and genome analysis for employment in the medical biotechnology/pharma and genomics sector, and those wishing to go on to do research degrees.

- This course will prepare you for entry into a career in medical genetics and genomics.

- Our lecturers conduct first-class research, with over 95% of Biological Science research internationally recognised in the 2014 REF.

- You will be taught by Oxford Brookes staff, with specialist lectures provided by staff of other partners in the Oxford Academic Health Sciences Centre, and will have a range of project opportunities using human genome data.

- The Faculty will invest over £8M in Bioscience facilities from 2015, with funding from HEFCE.

- Projects may be linked to specific needs and interests in the work-place, at Brookes or within other genomic laboratories under Brookes supervision. We also have strong links with local industry.

- We develop your transferable skills, particularly communication, organisation and research planning, which will assist you when carrying out your research project and can provide a basis for application for a research degree or career in genomics research.

Teaching and learning

The taught programme will be available with options for full-time and part-time MSc (180 credits), as well as individual CPD modules. Postgraduate Certificate and Diploma qualifications are also possible, requiring 60 and 120 credits, respectively.

Approach to assessment

Assessment methods used within the course are varied and are designed to be stimulating as well as academically rigorous. They are based on your learning needs, individual aims and the academic standards expected for the course.

You will receive unparalleled support from tutors and have access to state-of-the-art learning technologies via our Moodle platform. Our tutors have reputations for excellence and have established links with colleagues, organisations and institutions at national and international levels.

Embedded throughout the curriculum are skills that are essential to achieve quality outcomes for genomic medicine in practice. This will develop skills culminating in the research project, which will enable students to undertake research and evaluate new findings to implement in patient diagnosis, treatment and care, problem-based learning, work-based learning and inter-professional learning to develop skills for working in specialist and interdisciplinary teams. The development of skills in bioinformatics and use of genomic data will be a key outcome so the programme has a large proportion of hands on experience.

How this course helps you develop

You will develop the in-depth knowledge and specialised skills required to apply genetics and genomics theory to practical problems in the biomedical and pharmaceutical industries, and to undertake research in genetics and genome analysis.

Students will acquire knowledge and skills for employment or PhD positions in the expanding fields of genomics, bioinformatics, or other medically-related research, and academia.

During the course of this programme you will develop a network of colleagues and experts from this field.

Careers

- Research Degree/ PhD
- Pharmaceutical Industry
- Biomedical Industry
- NHS Scientist
- Medical Research
- Academia

Free language courses for students - the Open Module

Free language courses are available to full-time undergraduate and postgraduate students on many of our courses, and can be taken as a credit on some courses.

Please note that the free language courses are not available if you are:
- studying at a Brookes partner college
- studying on any of our teacher education courses or postgraduate education courses.

Research highlights

RESEARCH EXCELLENCE FRAMEWORK (REF) 2014
- Top post '92 University Biological Sciences submission

- 95% of research internationally recognised

- Double the percentage 4* and treble the percentage 3* research compared to 2008, with 58% of research being world leading or internationally excellent

- 80% of impact rated 3* or 4*

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The revolution in genetic mapping technology and the advent of whole genome sequences has turned quantitative genetics into one of the fastest growing areas of biology.

Quantitative Genetics & Genome Analysis is part of a suite of programmes offering specialist routes in Animal Breeding & Genetics, Evolutionary Genetics, or Human Complex Trait Genetics.

Based in the internationally renowned Institute of Evolutionary Biology, this MSc draws from the wealth of expertise available there, as well as the teaching, research expertise and facilities of Scotland’s Rural College, the University’s Centre for Molecular Medicine, the Medical Research Council’s Human Genetics Unit and the Roslin Institute (birthplace of Dolly the sheep).

Each year the syllabus is fine-tuned to suit current issues in evolutionary, plant, human and animal genetics.

Applicants who wish to select their area of specialisation during the programme should apply for this umbrella programme. Applicants with a preferred programme option should apply via the following links:

• Animal Breeding and Genetics
• Evolutionary Genetics
• Human Complex Trait Genetics

Programme structure

This programme consists of two semesters of taught courses followed by a research project, leading to a dissertation.

Compulsory courses

• Population and Quantitative Genetics
• Genetic Interpretation
• Statistics and Data Analysis
• Linkage and Association in Genome Analysis
• Research Proposal
• Dissertation

Option courses (selected according to degree specialisation):

• Quantitative Genetic Models
• Molecular Evolution
• Genetics of Human Complex Traits
• Animal Genetic Improvement
• Functional Genomic Technologies
• Molecular Phylogenetics
• Bioinformatics
• Evolutionary Quantitative Genetics

Career opportunities

You will develop the in-depth knowledge and specialised skills required to apply quantitative genetics theory to practical problems, in both the biomedical and animal science industries, and to undertake research in evolutionary genetics, population genetics and genome analysis.

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The revolution in genetic mapping technology and the advent of whole genome sequences have turned quantitative genetics into one of the fastest growing areas of biology.

Based in the internationally renowned Institute of Evolutionary Biology, this MSc draws from the wealth of expertise available there, as well as the teaching, research expertise and facilities of Scotland’s Rural College, the University’s Centre for Molecular Medicine, the Medical Research Council’s Human Genetics Unit and the Roslin Institute (birthplace of Dolly the sheep).

Each year the syllabus is fine-tuned to suit current issues in evolutionary, plant, human and animal genetics.

This programme forms part of the quantitative genetics and genome analysis suite of programmes offering specialist routes, which include Animal Breeding & Genetics and Evolutionary Genetics.

Programme structure

This programme consists of two semesters of taught courses followed by a research project, leading to a dissertation.

Courses are taught via lectures, tutorials, seminars and computer practicals. Assessment is by written examinations, in-course assignments and project work.

Compulsory courses:

• Population and Quantitative Genetics
• Genetic Interpretation
• Linkage and Association in Genome Analysis
• Genetics of Human Complex Traits
• Quantitative Genetic Models
• Statistics and Data Analysis
• Research Project Proposal
• Dissertation.

Option courses:

• Molecular Phylogenetics
• Bioinformatics
• Molecular Evolution
• Quantitative Genetic Models
• Functional Genomic Technologies
• Animal Genetic Improvement
• Evolutionary Quantitative Genetics

Learning outcomes

You will gain the knowledge and skills required to apply quantitative genetics theory to practical problems in the biomedical industry, and to undertake research in quantitative and population genetics and genome analysis.

• A thorough understanding of general concepts in population and quantitative genetics and genomics
• In-depth knowledge of complex trait genetics in humans
• A solid grounding in the statistical methods required for quantitative biology
• Development of independent research skills through individual mini- and maxi-research projects
• Development of generic skills (IT skills, experience in writing scientific papers, the ability to work independently)
• Presentation skills through student seminars, scientific presentation of project work and independent research projects.

Career opportunities

You will develop the in-depth knowledge and specialised skills required to apply quantitative genetics theory to practical problems, in both the biomedical and animal science industries, and to undertake research in evolutionary genetics, population genetics and genome analysis.

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Overview
Advances in molecular biology have enabled major developments in biotechnology which in turn has lead to huge advances in medicine, molecular biology and industry. Students choosing this MSc degree will enjoy a comprehensive course that covers the key aspects of practical and theoretical medically-related molecular biology, developing advanced skills in this area.

Description
The course is composed of a modular 120-credit taught component and a 60-credit research project and dissertation. The taught component covers a broad range of medical molecular topics and techniques and includes thorough laboratory training. The course is run in conjuncture with our School of Medicine to ensure that students gain a broad view of modern molecular biology and laboratory techniques.

Overseas Students
A two-year course aimed at students from non-European Union countries who come to the UK requiring pre-MSc level training in English language and basic pre-MSc molecular biology. The first year of this course will bring students up to a level where they will be capable of studying for a full MSc degree and it will develop English language skills to the minimum level required for MSc level learning. Year one will be run in conjunction with ELCOS (English Language Courses for Overseas Students). Students can obtain the minimal English certification for MSc entry.

Module list (1st year of English-life sciences modules)
The English language content and life sciences teaching are integrated to enable students to undertake MSc level life-sciences modules through the medium of English

Life-sciences for none native English speakers - 50 credits
Academic Writing & Grammar
Speaking & Listening
Ad.Vocabulary Use & Reading
Near Native English 1
Near Native English 2

Modules list: (for first year of 1 year course and 2nd year of 2 year course)

Semester 1
Molecular and Medical Techniques
Techniques of molecular biology and biotechnology
Medical microbes viruses and parasites
Development, cancer and the human body
Genomes and Genetics
IT skills for medical and molecular research

Semester2
Project preparation course
Medical Biotechnology
Cellular causes of disease
Biomarkers in autoimmunity

Summer term
Research Project (Experimental research into a medical/molecular or genetics research topic)

Aims and Objectives
* Provide an excellent grounding in laboratory techniques and a critical approach to research planning and implementation.
* Develop understanding of molecular biology and the molecular basis of disease.
* Develop transferable skills, including their ability to work as a member of a team, and communicate in scientific writing and speech.
* Provide the opportunity for students to gain and enhance skills required by research organisations and biotechnology companies.
*Provide the ability to attain a level required to carry out research for a higher degree (PhD) in medical molecular and related areas.

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This MSc aims to provide medical and science students with a comprehensive knowledge and understanding of the field of prenatal genetics and fetal medicine, specifically human genetics, human embryonic development and fetal medicine. There is a strong focus on the development of key skills and careers advice in the programme.

About this degree

Students will develop a knowledge and understanding of the field of prenatal genetics and fetal medicine, specifically in the areas of basic genetics and technology, genetic mechanisms, medical genetics, organogenesis and fetal development, gametogenesis and IVF, prenatal diagnosis and screening, fetal and perinatal medicine, and preimplantation genetic diagnosis and developing technology. They gain transferable skills including information technology, analysis of scientific papers, essay writing, seminar presentation, research techniques, peer review and laboratory skills.

Students undertake modules to the value of 180 credits.

The programme consists of eight core modules (120 credits) and a research project (60 credits).

A Postgraduate Diploma consisting of eight core modules (120 credits, full-time nine months, flexible study two to five years) is offered.

Mandatory modules

• Basic Genetics and Technology
• Gametogenesis, Preimplantation Development and IVF
• Genetic Mechanisms
• Medical Genetics
• Organogenesis and Fetal Development
• Prenatal Diagnosis and Screening
• Fetal and Perinatal Medicine
• Preimplantation Genetic Diagnosis and Developing Technology

Optional modules

There are no optional modules for this programme.

Dissertation/report

All MSc students undertake a clinical, laboratory, audit or library-based research project, which culminates in a dissertation of 10,000 words.

Teaching and learning

The programme is delivered through a combination of lectures, seminars, tutorials, practical demonstrations in laboratories, observation days in fetal medicine and IVF units, and student presentations. There are a number of peer-led learning activities. Assessment is through essays, patient case reports, critical reviews of papers, online problem booklet, examinations and the dissertation.

Further information on modules and degree structure is available on the department website: Prenatal Genetics and Fetal Medicine MSc

Funding

For a comprehensive list of the funding opportunities available at UCL, including funding relevant to your nationality, please visit the Scholarships and Funding website.

Careers

On completion of the programme, all students will have gained knowledge of both the clinical and laboratory aspects of prenatal genetics and fetal medicine. This will enable the science-orientated students to go on to pursue research degrees, further training for careers in prenatal diagnosis or embryology, or other careers in the field or in general science. Medically-orientated students will be able to develop their careers in the field of fetal medicine.

Recent career destinations for this degree

• Doctor, South West Yorkshire Partnership NHS Foundation Trust
• Senior Genetic Counsellor, King Faisal Specialist Hospital & Research Centre
• Trainee Clinical Embryologist, George's Memorial Medical Centre
• Clinical Research Nurse, UCL
• PhD in Prenatal Diagnosis, National and Kapodistrian University of Athens

Employability

Throughout the MSc programme students learn key skills through peer-led activities, such as evaluating and presenting orally on patient cases and media coverage of scientific papers. Students learn how to write essays and patient case reports and how to critically evaluate papers. They also have the opportunity to take part in debates and ethical discussions and to learn basic laboratory techniques. We offer a comprehensive careers programme involving our alumni, covering job applications, CV writing, general careers in science and specific advice on careers in embryology, clinical genetics, medicine and research degrees.

Careers data is taken from the ‘Destinations of Leavers from Higher Education’ survey undertaken by HESA looking at the destinations of UK and EU students in the 2013–2015 graduating cohorts six months after graduation.

Why study this degree at UCL?

The UCL Institute for Women’s Health delivers excellence in research, clinical practice, education and training in order to make a real and sustainable difference to women's and babies' health worldwide.

The institute's UCL/UCL Hospitals NHS Foundation Trust collaboration provides an academic environment in which students can pursue graduate studies taught by world-class researchers and clinicians.

Our diversity of expertise in maternal and fetal medicine, neonatology, reproductive health and women's cancer ensures a vibrant environment in which students develop subject-specific and generic transferable skills, supporting a broad range of future employment opportunities.

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Our Medical Genetics MRes is a research-based course with a taught component that is equivalent to an MSc. It provides a springboard into a career that involves a working knowledge of scientific research.

The course is designed for graduates with a BSc in the life sciences or other science disciplines, and for intercalating and fully qualified MBBS or BDS students. It can be taken either as a stand-alone qualification or as an entry route onto a PhD or MD.

The taught component of the course includes subject-specific content in the area of medical genetics. You have the flexibility to develop your own bespoke course by selecting additional, complementary modules. You will also participate in training in general research principles, and other professional and key skills.

Your research project comprises the major element of the course. This project will involve 24 weeks of research in an area of medical genetics under the supervision of an expert academic researcher in the field.

The course allows you to experience an internationally competitive research area, predominantly in academia but also potentially in industry.

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This course aims to inform and equip the practitioner with the necessary skills to function in a modern biomedical/clinical environment specialising in caring for the patient with a genetic disorder.

Why Study Medical Genetics with us?

You will receive training in the skills required in the reading and interpretation of the literature and translating that into evidence-based practice. We aim to develop your research and writing skills so that you will be in a position to contribute to the scientific literature in an effective manner.

The course culminates in the Research Dissertation, which will be assessed through your production of two publishable scientific articles.

The content of the course is mapped to The Joint Royal Colleges of Physicians Training Board Speciality Training Curriculum for Clinical Genetics.

If biomedical or clinical research is your interest, successful completion of the MSc will allow you to directly register onto PhD study and join our team of researchers at the Institute of Medicine.

What will I learn?

You will study how to apply molecular approaches to the diagnosis and treatment of a range of conditions that have a genetic component. We will discuss novel approaches to prevention and treatment, plus the increasing potential of genomics. We will also consider ethical implications of interventions, and the role/nature of genetic counselling. You will carry out a research project in one of these areas.

Seminars and tutorials will be held with various healthcare professionals and clinical researchers.

How will I be taught?

Our course consists of taught modules and a Research Dissertation.

We deliver taught modules as three-day intensive courses to facilitate attendance from students in employment. Weekly support sessions and journal club supplement learning – all held in our modern facilities in Bache Hall.

How will I be assessed?

You will be assessed via clinical reviews, laboratory reports, posters, oral presentations, or data manipulation exercises.

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The MSc Molecular Genetics and Diagnostics is suitable for graduates in life sciences, biomedical sciences and allied subjects, as well as people already employed in related fields who wish to improve and update their knowledge and gain valuable experience.

The course is designed to explain the technology, theory and practical approaches of molecular genetic methods to the diagnosis and understanding of human disease.

The course has a start date in September,

The course aims to:

• Provide an advanced course of study in the theoretical and practical aspects of the genetic basis and diagnosis of human disease
• Allow students adequate time to integrate into an active research laboratory where they are able to develop the skills which are essential when considering a career in research
• Train students to carry out critical evaluation of published scientific papers so that they develop the ability to report and interpret results

The academic staff involved with the course are recognised at an international level for their work on the genetic basis of complex diseases, including chronic obstructive pulmonary disease (COPD), Alzheimer's disease and infectious disease caused by clinically relevant microbial pathogens such as Pseudomonas spp., Yersinia spp. and Staphylococcus spp. Colleagues working in Molecular Diagnostics and Clinical Genetics within the NHS also contribute to the teaching on the course.

Key Facts

• The MSc Molecular Genetics and Diagnostics was previously known as the MSc Molecular Diagnostics, and has been running since 2004
• One of the many strengths of the course is the five-month research project that is conducted in the laboratory with a member research staff within the School
• The latest Research Assessment Exercise (RAE) confirmed The University of Nottingham's position as a world class research-led institution. Over 60% of the University's RAE scores identified research as being of a level of international excellence.
• This achievement has helped put Nottingham in the world’s top 1% of Universities internationally according to the latest (2014) QS World University Ranking.
• The peer-reviewed research carried out within the Human Genetics and Molecular and Cellular Bacteriology groups is recognized as being of either international or world-class standard.
• The MSc Molecular Genetics and Diagnostics is coordinated by academic staff within the Molecular and Cellular Bacteriology Research Group, part of the School of Life Sciences. Staff are based either within the Centre for Biomedical Science, a new state of the art research and teaching centre, the adjacent medical school which itself is located in the Queen’s Medical Centre or the Nottingham City Hospital.
• Extensive IT facilities are available across all campuses, including several computer rooms within the medical school.
• The University library service provides access to more than a million books and journals. The Greenfield Medical Library houses a broadly-based collection of biomedical, nursing and healthcare-related books and periodicals and holds current subscriptions to 780 journals, reports and series titles. In addition to the print versions housed in the library, the majority of journals can be accessed electronically.

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Genetics is the scientific study of inheritance and as such is a very broad research area. Within the School of Life Sciences, research in Genetics is focussed on the Institute of Genetics, most groups of which are located within the Queen's Medical Centre. Projects in genetics cover a wide spectrum from population and evolutionary genetics through to molecular and biochemical genetics. They have the common aim of understanding how the genetic material achieves its functions and how it is passed down through generations. Some of the research involves classic genetic approaches including the isolation of mutants with specific phenotypes and the study of their behaviour in genetic crosses. These studies involve model organisms that include bacteria, yeasts and other fungi, Xenopus, zebrafish and mice. Other research in Genetics at Nottingham employs molecular techniques and bioinformatics to address fundamental evolutionary problems such as the evolution of AIDS viruses, the genetic changes that are associated with speciation and the evolution of transposable elements and genome structure. There also projects available in Genetics research groups who are focussing on the systems responsible for maintaining gene and genome integrity and securing accurate chromosome transmission in bacteria, archaea, yeast and vertebrates.

APPLICATION PROCEDURES

After identifying which Masters you wish to pursue please complete an on-line application form
https://pgapps.nottingham.ac.uk/
Mark clearly on this form your choice of course title, give a brief outline of your proposed research and follow the automated prompts to provide documentation. Once the School has your application and accompanying documents (eg referees reports, transcripts/certificates) your application will be matched to an appropriate academic supervisor and considered for an offer of admission.

COURSE STRUCTURE
The MRes degree course consists of two elements:
160 credits of assessed work. The assessed work will normally be based entirely on a research project and will be the equivalent of around 10 ½ months full-time research work. AND
20 credits of non-assessed generic training. Credits can be accumulated from any of the courses offered by the Graduate School. http://www.nottingham.ac.uk/gradschool/research-training/index.phtml The generic courses should be chosen by the student in consultation with the supervisor(s).

ASSESSMENT
The research project will normally be assessed by a dissertation of a maximum of 30,000 to 35,000 words, or equivalent as appropriate*. The examiners may if they so wish require the student to attend a viva.
*In consultation with the supervisor it maybe possible for students to elect to do a shorter research project and take a maximum of 40 credits of assessed modules.

The School of Life Sciences will provide each postgraduate research student with a laptop for their exclusive use for the duration of their studies in the School.

SCHOLARSHIPS FOR INTERNATIONAL STUDENTS
http://www.nottingham.ac.uk/studywithus/international-applicants/scholarships-fees-and-finance/scholarships/masters-scholarships.aspx

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Your programme of study

Genetics at University of Aberdeen is taught at the heart of a very large teaching hospital at Foresterhill. This gives you access to experts within a wide variety of areas including bioinformatics, mendelian genetics, applied statistics and immunogenetics. The MSc degree in Genetics will take you through a wide-ranging curriculum describing some of the latest advances in genetics. You understand how diversity influences clinical outcomes, transplants, infections, autoimmune disease, cancer, immunodeficiency and human reproduction. We have the best support services in the UK to ensure you have guidance from the start.

Graduates from this programme can go on to work in hospital and research laboratories, projects at national and international level to understand health issues, training, scientific publishing, civil service, regulatory areas, government agencies and as consultants to regulators.

Courses listed for the programme

Semester 1

• Compulsory
• Bioinformatics
• Applied Statistics
• Generic Skills
• Basic Skills - Induction
• Introduction to Molecular Biology

Optional

• Introductory Immunology
• Introduction to Microbiology

Semester 2

• Genome - Enabled Medicine
• Research Tutorials
• Immunogenetics
• Mendelian Genetics

Semester 3

• Masters Research Project

Find out more detail by visiting the programme web page

Why study at Aberdeen?

• You are taught by leading genetics and bioscience researchers with immunogenetics unique to Aberdeen
• You have access to a large teaching hospital with dynamic research culture
• Researchers at Aberdeen invented insulin treatment winning the Nobel Prize

Where you study

• University of Aberdeen
• Full Time or Part Time
• 12 months or 24 months
• September start

International Student Fees 2017/2018

Find out about fees

*Please be advised that some programmes have different tuition fees from those listed above and that some programmes also have additional costs.

Scholarships

View all funding options on our funding database via the programme page

Living in Aberdeen

Find out more about:

Your Accommodation

• Catered Accommodation
• Self-Catering     

Campus Facilities

• University of Aberdeen: A Global Community
• University of Aberdeen: We are international
• Aberdeen City and Aberdeenshire
• Student Support
• Clubs and Societies
• Sport
• Societies
• Review

Find out more about living in Aberdeen and living costs

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The MSc in Genetic and Genomic Counselling is designed to give students a working knowledge of the principles and practice of Genetic Counselling which will qualify them to practice as Genetic and Genomic Counsellors. The programme will be delivered by University of Glasgow staff in collaboration with NHS staff from the West of Scotland Genetics Service, so that a current perspective on both laboratory diagnostics and clinical services will be obtained. This programme is accredited by the UK Genetic Counsellor Registration Board.

Why this programme

-◾Teaching is based at the Queen Elizabeth University Hospital (QEUH), which includes adult services, children’s services and maternity services, as well as one of the largest diagnostic laboratories in Europe, and a new, purpose-built teaching and learning facility. The close collaboration between University and NHS staff ensures that the MSc in Genetic and Genomic Counselling provides a completely up-to-date representation of genetic services.
◾Counselling and psychology theoretical and research-focused courses are delivered by University staff trained in psychology, providing a firm foundation for the subsequent acquisition of knowledge and skills in genetic counselling facilitated by GCRB-registered Genetic Counsellors.
◾The University of Glasgow Medical Genetics Teaching Staff won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering), to recognise and reward excellence and good practice; they were also finalists in the 2013 awards and are finalists in the category of "Outstanding support for students" in The Herald Higher Education Awards for Scotland in association with UWS 2016.
◾You will develop your skills in problem solving, evaluation and interpretation of diagnostic data, communication of the results of genome testing to patients, literature searches, scientific writing, oral presentations, poster presentations and team working.
◾The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.

Programme structure

Component courses are as follows:

Genetic Disease in Clinical Practice

This course is designed in collaboration with the West of Scotland Genetics Service to give students a working knowledge of the principles and practice of Clinical Genetics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease, and explore the links between genotype and phenotype.

Case Investigations in Medical Genetics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Distress or disorder: reactions to a medical diagnosis

Note: this 10 credit course may be taken by visiting students, for example as professional development.

This course outlines the process of psychosocial adjustment to a diagnosis or test result allowing participants to establish if and when a distress reaction develops into an adjustment disorder. The implications of diagnosis are explored and evidence considered allowing informed decisions about appropriate referrals to other agencies.

Patient empowerment: supporting decisions relating to new diagnoses

Note: this 10 credit course may be taken by visiting students, for example as professional development.

This course reflects on evidence and experience to explore the psychological and social impact of a diagnosis, or illness, and provides strategies to support resilience and coping in patients. Factors related to lived experience, personal beliefs and values, culture, adjustment processes, decision-making, misconceptions, secrecy and guilt are considered to equip participants in the promotion of patient-centred care.

Effective listening and communication skills

Note: this 10 credit course may be taken by visiting students, for example as professional development.

With a focus on experiential learning and student led study, this course outlines the role of counselling skills to facilitate adjustment and to allow an individual to come to terms with change in a safe way to minimise impact. The focus will be on the theory supporting counselling, developing key listening and communication skills and on establishing reflective practice.

Genetic counselling in clinical practice

This course is designed in collaboration with the West of Scotland Clinical Service, and will be delivered by NHS staff, to provide students with in depth understanding of the practical skills required in genetic counselling. The course will facilitate development of appropriate critical understanding, reflective practice and skills in relation to genetic counselling for providing accurate complex genetic information for patients and their families.

Social science research methods

The research methods course will focus on developing students’ research skills primarily in questionnaire-based qualitative and quantitative observational research methods and students will be introduced to ethics procedures for the college of MVLS.

Community placements 1 & 2

These placements, for 16 days and 20 days respectively, will each take place in one or more care settings for individuals with complex needs (adults or children or both) to enable students to gain insight into effects of complex needs on affected individuals and on their family.

Genetic counselling placement 1 & 2

These placements, for eight weeks and six weeks respectively, in different genetics centres will allow students to observe clinical practice in a variety of contexts, and to undertake relevant tasks under supervision within a clinical team that is delivering a genetic service, to enable the student to develop their own skills as a future genetic counsellor. Following each placement students will discuss and share experiences, facilitated by one of the NHS lead team and a counselling supervisor, to further develop their ability to deal with practical and emotional challenges in genetic counselling.

Clinical genomics

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussing the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Career prospects

The programme aims to provide students with skills to work as Genetic Counsellors. This programme is accredited by the Genetic Counsellor Registration Board (GCRB) producing graduates who are eligible for entry as a ‘trainee genetic counsellor’.

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