Masters Degrees in Developmental Biology, United Kingdom

This course provides comprehensive training in molecular cellular and developmental biology, with particular emphasis on animal systems. If you're looking to develop new skills for your career, or prepare for a higher degree such as an MSc or PhD, this is an ideal refresher or top-up course.

We’ll also give you practical training in modern molecular cell biology laboratory techniques, including experimental design, analysis and presentation.

You'll gain in-depth knowledge and understanding of the processes that govern embryonic development. You’ll also learn about the molecular and genetic processes that underpin cell biology of body systems.

Lectures and practicals will highlight the relevance of developmental and cell biology to the fields of stem cell and cancer biology, cellular homeostasis and tissue regeneration, and to the process of normal ageing.

Core modules

Advanced Developmental Biology
Advanced Molecular Biology
Practical Molecular Cell Biology

Teaching

Lectures
Laboratory sessions

Assessment

Essays
Practical work
Exams

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Developmental biology is the science of the processes governing the growth and development of organisms. This programme focuses on the fundamentals of developmental biology in a range of vertebrates, including studies of the genes and molecules that control cell growth, differentiation and morphogenesis that give rise to tissues, organs and individuals.

The MRes provides a unique mix of taught components, extended laboratory projects, literature reviews and preparation of a grant proposal based on a research dissertation. It gives students an insight into a range of state-of-the-art research activities and techniques, and provides generic, transferable skills training needed for all early stage researchers. The programmes also address the scientific, ethical and commercial context within which the research takes place.

All of the MRes programmes can be studied as the first year of our Integrated PhD programme.

Visit the website http://www.bath.ac.uk/science/graduate-school/taught-programmes/mres-developmental-biology/

Why study Biology and Biochemistry with us?

- Biology & Biochemistry ranked 2nd in the Sunday Times University Guide 2013
- 90% of our research judged to be internationally recognised, excellent or world-leading
- Our current research funding portfolio stands at £14 million, supporting internationally excellent research in the biosciences

What will I learn?

MRes degree programmes are designed for graduates who are contemplating a research career and who may go on to study for a PhD or to a position in industry involving interaction with research scientists.

If these do not apply, you might consider an MSc programme (http://www.bath.ac.uk/science/graduate-school/taught-programmes/).

For further details please visit our department pages (http://www.bath.ac.uk/bio-sci/)

Career opportunities

Since graduating, our students have gone on to employment or further research at institutions in the US, Europe, Australia, Asia and Africa.

Recent employers include:

Morvus-Technology Ltd
Janssen-Cilag
Royal United Hospital, Bath
Ministry of Defence
State Intellectual Property Office, Beijing
Wellcome Trust Centre for Human Genetics, Oxford University
AbCam
Salisbury Foundation Trust Hospital
BBSRC
Lonza

Find out more about the department here - http://www.bath.ac.uk/bio-sci/

Find out how to apply here - http://www.bath.ac.uk/science/graduate-school/taught-programmes/how-to-apply/

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Developing your knowledge and skills for a scientific/clinical career

As a graduate in the life-sciences, this MSc in Reproductive and Developmental Biology can help you reach the next stage of your career - be that PhD posts, entry to medical school, or clinical speciality training. With both a full-time MSc and a PGCert (Postgraduate Certificate) on offer, you can choose the pathway most suited to you, and use the specific scientific skills and the transferable skills we give you to take the next step.

Is this programme for you?

Applicants to this course are looking to improve your theoretical knowledge in the areas of reproductive and developmental biology, alongside gaining practical skills within a vibrant research environment.

Please note that we do not provide training in any technologies or techniques of Assisted Reproduction (IVF); however, previous students have gained places on the highly competitive Scientist Training Programme that is now required for those who wish to work as embryologists within the NHS.

You will need to be an independent person, who is looking for a challenge. If you're not afraid of hard work, then we would welcome an application from you.

Application

Offers are made on a first-come, first served basis. Once places are filled, we will close to new applications, so ensure that you submit your application sooner, rather than later.

You will receive notification of a conditional offer or rejection in the weeks following your submission. If you do not hear from us, it is because you have been placed on the waiting list.

Please note that we are unable to consider your application without at least one academic reference from your most recent institution.

Programme structure

Both courses start with six months of teaching on our current understanding of key topics in reproductive and developmental biology. This is split into 6 topics:

•Development of the Male and Female Reproductive Systems
•Endocrinology - Activation of the Gonads and Regulation of Gametogenesis
•Fertilisation and Early Embryo Development
•Experimental Approaches to Improved Understanding of Reproduction and Development
•Pregnancy
•Development and Stem Cell Biology

During this taught component, you will receive practical training in, for example:

•Microscopy (dissection, confocal, and fluorescence)
•QPCR
•Western Blotting

You will be assessed throughout the course component, with the PG Certificate concluding with the final examination in March. At this point, MSc students will enter their research project.

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This programme focuses on the science of the processes governing the growth and development of organisms. It includes studies of the genes and molecules that control cell growth, differentiation and morphogenesis that give rise to tissues, organs and individuals.

The department has outstanding facilities for experimental work using a range of model vertebrate organisms.

The MSc programmes in Biology & Biochemistry are designed for students who wish to specialise further in a particular field or wish to change direction from their first degree (in a related area).

If you already have extensive and relevant research experience and would like to specialise, you might consider an MRes programme (http://www.bath.ac.uk/science/graduate-school/taught-programmes/).

Why study Biology and Biochemistry with us?

- Biology & Biochemistry ranked 2nd in the Sunday Times University Guide 2013
- 90% of our research judged to be internationally recognised, excellent or world-leading
- Our current research funding portfolio stands at £14 million, supporting internationally excellent research in the biosciences

What will I learn?

The aim of each of our MSc programmes in Biology and Biochemistry is to provide professional-level training that will develop highly skilled bioscientists with strong theoretical, research and transferable skills, all of which are necessary to work at the forefront of modern biosciences.

For further information please see our department pages (http://www.bath.ac.uk/bio-sci/)

Career opportunities

Since graduating, our students have gone on to employment or further research at institutions in the US, Europe, Australia, Asia and Africa.

Recent employers include:

Morvus-Technology Ltd
Janssen-Cilag
Royal United Hospital, Bath
Ministry of Defence
State Intellectual Property Office, Beijing
Wellcome Trust Centre for Human Genetics, Oxford University
AbCam
Salisbury Foundation Trust Hospital
BBSRC
Lonza

Find more about the department here - http://www.bath.ac.uk/bio-sci/

Find out how to apply here - http://www.bath.ac.uk/science/graduate-school/taught-programmes/how-to-apply/

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Within the Developmental Biology research area a number of model systems are being used to study various aspects of vertebrate development with a major focus being on the development of stem cells. Specific projects include: the development of blood stem cells and vasculature in zebrafish; the development of neural stem cells in zebrafish and in mice; the properties of mesenchymal stem cells; primordial germ cells and gene networks that govern the development of vertebrate embryos.

APPLICATION PROCEDURES

After identifying which Masters you wish to pursue please complete an on-line application form
http://www.nottingham.ac.uk/pgstudy/apply/apply-online.aspx

Mark clearly on this form your choice of course title, give a brief outline of your proposed research and follow the automated prompts to provide documentation. Once the School has your application and accompanying documents (eg referees reports, transcripts/certificates) your application will be matched to an appropriate academic supervisor and considered for an offer of admission.

COURSE STRUCTURE
The MRes degree course consists of two elements:
160 credits of assessed work. The assessed work will normally be based entirely on a research project and will be the equivalent of around 10 ½ months full-time research work. AND
20 credits of non-assessed generic training. Credits can be accumulated from any of the courses offered by the Graduate School. http://www.nottingham.ac.uk/gradschool/research-training/index.phtml The generic courses should be chosen by the student in consultation with the supervisor(s).

ASSESSMENT
The research project will normally be assessed by a dissertation of a maximum of 30,000 to 35,000 words, or equivalent as appropriate*. The examiners may if they so wish require the student to attend a viva.
*In consultation with the supervisor it maybe possible for students to elect to do a shorter research project and take a maximum of 40 credits of assessed modules.

The School of Life Sciences will provide each postgraduate research student with a laptop for their exclusive use for the duration of their studies in the School.

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This MSc is aimed at students who wish to extend their knowledge and expertise in the eye as an integrated biological system. The programme provides a unique and integrated review of the physiology and biology of the eye, covering molecular and developmental cell biology, complex genetics, immunology and behavioural neuroscience.

Degree information

The programme offers students the opportunity to develop their knowledge and expertise in ocular cell biology, genetics, visual neuroscience, development and immunology. On completion of the programme, students gain an enhanced knowledge and understanding of scientific communication skills, scientific design and analysis, sophisticated laboratory techniques and valuable research experience.

Students undertake modules to the value of 180 credits. The programme consists of four core modules (60 credits), one or two optional modules (30 credits) and a research project (90 credits).

Core modules
-Ocular Cell Biology
-Genetics and Epidemiology of Ocular Disease
-Ocular Immunology
-Ocular Development in Health and Disease

Optional modules
Either
-Advanced Visual Neuroscience (30 credits)
Or
-Microvascular Biology (15 credits) and Visual Neuroscience (15 credits)

Dissertation/research project
All MSc students undertake either a research or informatics project using state-of-the-art techniques and equipment. The project culminates in a dissertation of 15,000–18,000 words.

Teaching and learning
The programme is delivered through a combination of lectures, seminars, tutorials, problem classes, journal clubs, self-directed studies and laboratory practical courses. Assessment is through long essays, coursework, laboratory practicals, oral examination and the research dissertation.

Careers

This programme provides excellent preparation for a PhD or a successful research career in academia or for positions in the public or commercial sectors. Previous students have also successfully obtained specialist trainee positions in ophthalmology at hospitals across the country.

Top career destinations for this degree:
-PG Dip Clinical Ophthalmology, University College London (UCL)
-Research Degree: Institute of Ophthalmology, University College London (UCL)
-Doctor, Mile End Hospital (NHS)
-GP (General Practitioner), Barnet Hospital (NHS)
-Research Associate, Sandwell and West Birmingham Hospitals NHS Trust

Employability
The programme aims to train first-class basic and clinical scientists in the field of ophthalmology.

Why study this degree at UCL?

The UCL Institute of Ophthalmology is one of the premier centres in the world for the study of vision and the mechanisms, diagnosis and therapy of eye disease. We embrace fundamental research, through the entire spectrum of translational medicine to clinical trials.

This MSc programme draws upon the extensive basic and clinical research experience available at the institute and at Moorfields Eye Hospital. Students gain expertise in basic cell biology, genetics, neuroscience and physiology, specialise in the biology of the eye as an integrated biological system and conduct a six-month research project within a world-class research environment.

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The Master of Science by Research degree in Marine Biology is a 12-month, research only degree, in which the candidate will undertake a supervised research project in the area of Marine Biology, in the School of Biology, University of St Andrews.

The candidate will be based in the interdisciplinary Scottish Oceans Institute (SOI), based at East Sands, St Andrews. The SOI is home to the world famous Sea Mammal Research Unit (SMRU), and hosts a wide-range of researchers with interests ranging from the deep oceans to the coasts, and from the people who use and interact with the sea, to the biological and physical processes that make the oceans function.

There are four research themes running through the SOI: Global Change and Planetary Evolution; Ecology, Fisheries and Resource management; Developmental and Evolutionary Genomics; the Sea Mammal Research Unit. As such, the SOI brings together behavioural and population ecologists, evolutionary biologists, geneticists, conservationists, mathematicians and environmental scientists to contribute towards understanding and managing the future of our oceans and the organisms, big and small, that live within them. Further details about the SOI can be found here: http://soi.st-andrews.ac.uk/.

Candidates may approach potential supervisors in the SOI directly (https://synergy.st-andrews.ac.uk/research/phd-study/phd-study-supervisors/phd-study-soi-supervisors/) or via advertised projects listed here (https://synergy.st-andrews.ac.uk/research/mscres/). We strongly recommend that potential candidates make contact with a potential supervisor before applying.

The School of Biology provides a unique and supportive environment for scholarship, amid a beautiful setting for university life. We are a highly research active School, with a diverse and vigorous post-graduate community. The School comprises a large number of research groups organised into three interdisciplinary Research Centres: the Scottish Oceans Institute (SOI), the Biomedical Sciences Research Complex (BSRC) and the Centre for Biological Diversity (CBD). Together these centres encompass the full spectrum of research in biological sciences, spanning investigations on the properties and behaviour of individual molecules through to planetary environmental dynamics. Our postgraduate students enjoy a supportive and welcoming environment, including the student-led ‘Bionet’ society that provides a wide range of networking and social opportunities.

Progression and Assessment

Students in the MSc(Res) program will be assigned an Internal Examiner (IE) and Post-Graduate Tutor by the School. There will be a progress review meeting at three months to monitor and evaluate student progression, convened by the IE, with the student and Tutor in attendance.

In addition to the project-specific training that you will receive during your degree, Msc(Res) students will also have access to a wide range of training in transferable skills through the award-winning University of St Andrews GradSkills program, run by our Professional Development Unit CAPOD. Specific post-graduate programs run within the School of Biology may also offer additional training, for instance in statistical, bioinformatics or molecular techniques.

The degree requires submission and examination of a dissertation at the end of the one-year program. This thesis will consist of up to 30,000 words. The thesis will be evaluated by the IE and an External Examiner appointed at time of submission. Evaluation will be based on the written submission and there is no requirement for a viva voce examination.

Fees

For details of post-graduate tuition fees relevant to our research degrees including the MSc(Res), please visit:
http://www.st-andrews.ac.uk/study/pg/fees-and-funding/research-fees/

Application

Please apply via the University’s Post-Graduate Application portal: https://www.st-andrews.ac.uk/pgr/home.htm

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About the course

Our department is home to a world-renowned sensory neuroscience research group. Their projects provide the basis for teaching and research training on this MSc.

The course covers molecular, cell and developmental biology of auditory and visual systems. Advanced imaging and behavioural analysis focus on information processing: from sensory transduction to the central nervous system and behaviour. You’ll also study animal models of sensory deficits and the development of therapeutic treatments for hearing loss and blindness.

Where your masters can take you

Graduates with skills in stem cell and regenerative medicine are in demand. Your degree will prepare you for a career in research in academia or industry, or in a clinical-related field. Our graduates are working all over the world – from the UK to China, India and the USA – and over half go on to doctoral study.

Learn from the experts

The 2014 Research Excellence Framework (REF) rates us No 1 in the UK for research in this field. Our international reputation attracts highly motivated staff and students. Sheffield is a vibrant place to take a masters based on pioneering research.

Regular seminars from distinguished international experts help you to connect your studies to the latest developments. We’re also part of collaborative research groups for developmental biology, cell biology, physiology, pharmacology, neuroscience, models of human disease, stem cell science and regenerative medicine.

Our three research centres focus on translating laboratory research to the clinical environment: Bateson Centre, the Centre for Stem Cell Biology, and the Centre for Membrane Interactions and Dynamics.

Leaders in our field

We have a long track record of groundbreaking discoveries. These include breakthroughs in human stem cells for hearing repair, and the generation of animal models for Parkinson’s disease, schizophrenia, muscular dystrophies and their use for therapeutic studies.

Labs and equipment

We have purpose-built facilities for drosophila, zebrafish, chick and mouse genetics and for molecular physiology. Other facilities provide all the tools you’ll need to examine and analyse a range of cellular structures. We have an electron and a light microscopy centre, a PCR robotics facility, a flow cytometry unit and an RNAi screening facility.

Teaching and assessment

There are lectures, practical classes, tutorials and seminars. In small group teaching classes you’ll discuss, debate and present on scientific and ethical topics. Laboratory placements within the department provide you with one-to-one attention, training and support to do your individual research project. Assessment is by formal examinations, coursework assignments, debates, poster presentations and a dissertation.

Our teaching covers ethics, practical scientific skills and an overview of the current literature. You’ll also develop useful career skills such as presentation, communication and time management.

Core modules

Literature Review; Practical Research Project; Analysis of Current Science; Ethics and Public Understanding.

Examples of optional modules

Integrated Mammalian Biology; Practical Developmental Genetics; Neuroscience Techniques; Sensory Neuroscience; Developmental Neurobiology; Computational Neuroscience.

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Research projects are available in the field of Molecular Cell Biology that include; the analysis of structure, function and dynamics of telomeres in yeast and parasites, and of centromeric DNA in mammalian cells; investigation of stress-response networks in the nematode Caenorhabditis elegans and of micro RNAs during the evolution of developmental processes in Drosophila; establishment of the relationship between nuclear structure and function using the giant nuclei of amphibian oocytes; analysis of biological membranes, biomaterials and biophysical aspects of cellular interactions as well as filopodia, lamellipodia and stress fiber formation; investigation of blood substitutes from microbial cell factories and of artificial gas-carrying fluids for enhancing growth of cells in culture.

APPLICATION PROCEDURES

After identifying which Masters you wish to pursue please complete an on-line application form
https://pgapps.nottingham.ac.uk/
Mark clearly on this form your choice of course title, give a brief outline of your proposed research and follow the automated prompts to provide documentation. Once the School has your application and accompanying documents (eg referees reports, transcripts/certificates) your application will be matched to an appropriate academic supervisor and considered for an offer of admission.

COURSE STRUCTURE
The MRes degree course consists of two elements:
160 credits of assessed work. The assessed work will normally be based entirely on a research project and will be the equivalent of around 10 ½ months full-time research work. AND
20 credits of non-assessed generic training. Credits can be accumulated from any of the courses offered by the Graduate School. http://www.nottingham.ac.uk/gradschool/research-training/index.phtml The generic courses should be chosen by the student in consultation with the supervisor(s).

ASSESSMENT
The research project will normally be assessed by a dissertation of a maximum of 30,000 to 35,000 words, or equivalent as appropriate*. The examiners may if they so wish require the student to attend a viva.
*In consultation with the supervisor it maybe possible for students to elect to do a shorter research project and take a maximum of 40 credits of assessed modules.

The School of Life Sciences will provide each postgraduate research student with a laptop for their exclusive use for the duration of their studies in the School.

SCHOLARSHIPS FOR INTERNATIONAL STUDENTS
http://www.nottingham.ac.uk/studywithus/international-applicants/scholarships-fees-and-finance/scholarships/masters-scholarships.aspx

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The course provides training in reproductive and developmental medicine for scientists, clinicians and others, for instance ethical advisers or lawyers looking to specialise. It’s a good platform for a research career or a career in clinical laboratory training for IVF or embryology. Through the taught modules you’ll develop a solid understanding of reproductive science relevant to clinical applications.
We cover the breadth of processes from gonadal development and production of gametes through to pregnancy and parturition. Each module is taught by leading scientists and clinicians in that field. You’ll also have the opportunity to learn about the ethical issues and international laws regulating reproductive medicine. Finally, you’ll undertake a research project to develop a depth of knowledge in a specialist topic.

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About the course

Lead academic 2016: Dr Mark Fenwick

The course provides training in reproductive and developmental medicine for scientists, clinicians and others, for instance ethical advisers or lawyers looking to specialise. It’s a good platform for a research career or a career in clinical laboratory training for IVF or embryology.

Through the taught modules you’ll develop a solid understanding of reproductive science relevant to clinical applications. We cover the breadth of processes from gonadal development and production of gametes through to pregnancy and parturition. Each module is taught by leading scientists and clinicians in that field.

You’ll also have the opportunity to learn about the ethical issues and international laws regulating reproductive medicine. Finally, you’ll undertake a research project to develop a depth of knowledge in a specialist topic.

Our study environment

You’ll be based in teaching hospitals that serve a population of over half a million people and refer a further two million. We also have close links with the University’s other health-related departments.

Our research funding comes from many sources including the NIHR, MRC, BBSRC, EPSRC, the Department of Health, EU, and prominent charities such as the Wellcome Trust, ARC, YCR, Cancer Research UK and BHF. Our partners and sponsors include Novartis, GlaxoSmithKline, Pfizer, Astra Zeneca and Eli Lilly.

You’ll also benefit from our collaboration with the Department of Biomedical Sciences.

How we teach

Classes are kept small (15–20 students) to make sure you get the best possible experience in laboratories and in clinical settings.

Our resources

We have a state-of-the-art biorepository and a £30m stem cell laboratory. The Sheffield Institute of Translational Neuroscience (SITraN) opened in November 2010. We also have microarray, genetics, histology, flow cytometry and high-throughput screening technology, and the latest equipment for bone and oncology research.

At our Clinical Research Facility, you’ll be able to conduct studies with adult patients and volunteers. The Sheffield Children’s Hospital houses a complementary facility for paediatric experimental medical research.

Hepatitis B policy

If your course involves a significant risk of exposure to human blood or other body fluids and tissue, you’ll need to complete a course of Hepatitis B immunisation before starting. We conform to national guidelines that are in place to protect patients, health care workers and students.

Core modules

Research Skills in Reproductive Medicine; Gonads to Gametes: fundamentals of reproduction; Fertilisation, Implantation and Embryology; Fetal Development, Pregnancy and Parturition; Reproductive Technology and Infertility; Law, Ethics and Policy in Reproductive Medicine.

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Modern genetics has today evolved beyond its traditional boundaries to become a fundamental part of biology and medicine. The Department reflects this pervasiveness, with research interests encompassing several high impact themes, including functional genomics and systems biology, developmental genetics, epigenetic Inheritance, evolution and population genetics, microbial genetics, and cell biology. The Department of Genetics hosts between 50 and 65 postgraduate students across 25 research groups, researching a wide range of biological problems, from population genetics and ecology, to the detailed analysis of genome sequence. The Department is based in a historic building on the Downing Site but has research groups located in the Gurdon Institute, Cambridge Systems Biology Centre and Sainsbury Labs as well as an impressive range of local, national and international collaborations.

MPhil students in the Department will undertake a 1-year project under the supervision of one of our Group Leaders, where they will develop an original research question and address this through laboratory or computer based research. They will receive training in appropriate research methods and in literature research skills to prepare them for writing an MPhil thesis within the year.

See the website http://www.graduate.study.cam.ac.uk/courses/directory/blgempmbs

Course detail

By the end of the programme, students will have:

- a comprehensive understanding of techniques, and a thorough knowledge of the literature, applicable to their own research;
- demonstrated originality in the application of knowledge, together with a practical
- understanding of how research and enquiry are used to create and interpret knowledge in their field;
- shown abilities in the critical evaluation of current research and research techniques and methodologies;
- demonstrated some self-direction and originality in tackling and solving problems, and acted autonomously in the planning and implementation of research.

Format

- Supervision meetings once every one or two weeks.

- Weekly Departmental seminars.

- Annual Research In Genetics day with poster sessions

Assessment

Thesis required of not more than 20,000 words in length, excluding figures, tables, footnotes, appendices and bibliography. The examination will include an oral examination on the thesis and on the general field of knowledge within which it falls.

Continuing

Candidates wishing to progress to the PhD degree after successful completion of an MPhil will be considered by the Departmental Graduate Education Committee on a case by case basis. Candidates will be expected to have identified a suitable research group to host the PhD research and identify an appropriate source of funding.

How to apply: http://www.graduate.study.cam.ac.uk/applying

Funding Opportunities

There are no specific funding opportunities advertised for this course. For information on more general funding opportunities, please follow the link below.

General Funding Opportunities http://www.graduate.study.cam.ac.uk/finance/funding

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This programme focuses in particular on modern research in developmental biology, stem cell biology and tissue engineering with its potential applications to medicine and is a collaborative programme within the Centre for Regenerative Medicine.

The MRes provides a unique mix of taught components, extended laboratory projects, literature reviews and preparation of a grant proposal based on a research dissertation.It gives students an insight into a range of state-of-the-art research activities and techniques, and provides generic, transferable skills training needed for all early stage researchers. The programmes also address the scientific, ethical and commercial context within which the research takes place.All of the MRes programmes can be studied as the first year of our Integrated PhD programme.

Visit the website http://www.bath.ac.uk/science/graduate-school/taught-programmes/mres-regen-medicine/

Why study Biology and Biochemistry with us?

- Biology & Biochemistry ranked 2nd in the Sunday Times University Guide 2013
- 90% of our research judged to be internationally recognised, excellent or world-leading
- Our current research funding portfolio stands at £14 million, supporting internationally excellent research in the biosciences

What will I learn?

MRes degree programmes are designed for graduates who are contemplating a research career and who may go on to study for a PhD or to a position in industry involving interaction with research scientists.

If these do not apply, you might consider an MSc programme (http://www.bath.ac.uk/science/graduate-school/taught-programmes/).

For further information please visit our department pages (http://www.bath.ac.uk/bio-sci/)

Career opportunities

Since graduating, our students have gone on to employment or further research at institutions in the US, Europe, Australia, Asia and Africa.

Recent employers include:

Morvus-Technology Ltd
Janssen-Cilag
Royal United Hospital, Bath
Ministry of Defence
State Intellectual Property Office, Beijing
Wellcome Trust Centre for Human Genetics, Oxford University
AbCam
Salisbury Foundation Trust Hospital
BBSRC
Lonza

Find out more about the department here - http://www.bath.ac.uk/bio-sci/

Find out how to apply here - http://www.bath.ac.uk/science/graduate-school/taught-programmes/how-to-apply/

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Molecular genetics is the study of genes at the molecular level. It focuses on the processes that underlie the expression of the genetic information from the DNA into the functional proteins that execute the genetic programme. Within the School of Life Sciences research in molecular genetics is concentrated in the Human Genetics, Fungal Biology, and Developmental Genetics and Gene Control groups. In the Human Genetics group research in this area includes studies of the molecular basis of myotonic dystrophy and the identification of genes involved in cardiac development; the molecular genetics of muscle disease; mouse models of muscle disorders and molecular genetic approaches to anthropology and human population genetics. In the Fungal Biology group there are studies on the molecular events that determine stress responses during polarised growth, protein folding and secretion in yeasts and filamentous fungi; the molecular and cellular effects of stress on yeast cells and the genetic mechanisms that control sex in fungi. The Developmental Genetics and Gene Control group focuses on the mechanisms of eukaryotic gene expression and the genetics of vertebrate embryonic development. Developmental studies are focussed largely upon the mechanisms that control stem cell fate. Projects on the control of gene expression address the machinery used by cells to achieve appropriate levels of functional transcripts. These studies include control of transcription and the mechanisms of RNA maturation.

APPLICATION PROCEDURES
After identifying which Masters you wish to pursue please complete an on-line application form
https://pgapps.nottingham.ac.uk/
Mark clearly on this form your choice of course title, give a brief outline of your proposed research and follow the automated prompts to provide documentation. Once the School has your application and accompanying documents (eg referees reports, transcripts/certificates) your application will be matched to an appropriate academic supervisor and considered for an offer of admission.

COURSE STRUCTURE
The MRes degree course consists of two elements:
160 credits of assessed work. The assessed work will normally be based entirely on a research project and will be the equivalent of around 10 ½ months full-time research work. AND
20 credits of non-assessed generic training. Credits can be accumulated from any of the courses offered by the Graduate School. http://www.nottingham.ac.uk/gradschool/research-training/index.phtml The generic courses should be chosen by the student in consultation with the supervisor(s).

ASSESSMENT
The research project will normally be assessed by a dissertation of a maximum of 30,000 to 35,000 words, or equivalent as appropriate*. The examiners may if they so wish require the student to attend a viva.
*In consultation with the supervisor it maybe possible for students to elect to do a shorter research project and take a maximum of 40 credits of assessed modules.

The School of Life Sciences will provide each postgraduate research student with a laptop for their exclusive use for the duration of their studies in the School.

SCHOLARSHIPS FOR INTERNATIONAL STUDENTS
http://www.nottingham.ac.uk/studywithus/international-applicants/scholarships-fees-and-finance/scholarships/masters-scholarships.aspx

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A Masters’ studentship is available in the group of Dr. Martin Schröder in the School of Biological and Biomedical Sciences at Durham University to study stress signaling mechanisms originating from the endoplasmic reticulum. Endoplasmic reticulum (ER) stress contributes to the development and progression of many diverse diseases affecting secretory tissues, such as diabetes and neurodegenerative diseases. The successful candidate will employ modern genetic and molecular techniques to understand the underlying cell biological mechanisms in endoplasmic reticulum stress signaling that maintain the homeostasis of the endoplasmic reticulum.

The MRes student will investigate control of ER stress signaling specificity by the dosage of ER stress. You will use a range of molecular biology and biochemical techniques to study (a) how the severity of ER stress alters the signaling outputs of the ER stress sensing protein kinase-endoribonuclease IRE1 or (b) how ER stress regulates transcriptional responses through the Rpd3-Sin3 histone/lysine deacetylase (see for example Schröder et al., 2000; Schröder et al., 2004). These techniques include protein expression and purification, immunoprecipitation, chromatin immunoprecipitation, cloning, transfection, and RNA analysis by real-time PCR or Northern blotting.

Overall, the studentship will provide interdisciplinary training in molecular biology, genetics, and cell biology.

References

M. Schröder, Cell. Mol. Life Sci. 65 (2008) 862-894: Endoplasmic reticulum stress responses.
M. Schröder, C. Y. Liu, R. Clark, and R. J. Kaufman, EMBO J. 23 (2004) 2281-2292: The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase.
M. Schröder, J. S. Chang, and R. J. Kaufman, Genes Dev. 14 (2000) 2962-2975: The unfolded protein response represses nitrogen-starvation induced developmental differentiation in yeast.

To apply

To apply: send a CV including the names of two references and a one page personal statement describing clearly your background, interest and experience in scientific research to [email protected]. In your cover letter you should clearly identify the funding source to cover living expenses, tuition fees and bench fees. Further information can be found at https://www.dur.ac.uk/martin.schroeder or by contacting Dr. Martin Schroeder.

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