The MRes in Biomedical Research: Bacterial Pathogenesis and Infection is a 12 month postgraduate course providing exemplary academic and research training. The Bacterial Pathogenesis and Infection stream is a specialised stream on a larger course (the MRes in Biomedical Research). This programme will provide research training in fundamental aspects of bacterial pathogenesis, host immunity and antibiotic resistance, with particular attention to the scientific, technical and professional acumen required to establish research independence. The emphasis will be on molecular approaches to understanding bacterial infection biology, as a function of bacterial pathogenic strategy and physiology, as well as resistance to host defences and antibiotic therapy, and is comprised of two 20-week research projects embedded within research-intensive groups and a series of lectures, seminars, tutorials and technical workshops.
Based in the MRC Centre for Molecular Bacteriology and Infection, the course provides an opportunity to learn directly from internationally-respected scientists through sustained interaction for the duration of the course. This programme will deliver training in: Molecular microbiology, including integration of molecular and cellular information to understand the genetic basis of virulence; modelling host and microbial aspects of infection to help characterise the host-pathogen interaction and immunity; functionality and physiological relevance of microbial virulence factors; mechanisms of antibiotic resistance and persistence; derivation of mechanistic approaches to problem-solving in molecular and cellular biomedical science.
Course Objectives The emphasis is on molecular approaches to understanding infection as a function of bacterial pathogenic strategy and physiology. This research-oriented approach to training in biomedical science will comprise both theoretical and practical elements. The course will expose students to the latest developments in the field through two mini-research projects and a series of technical workshops. Students will gain experience in applying technologically advanced approaches to biomedical research questions.
Specifically the course will deliver research training in:
• Molecular bacteriology, integrating molecular and cellular information to understand the genetic basis of microbial virulence. • Modelling host and microbial aspects of infection to help characterise the host-pathogen interaction and immunity. • By experimentation, understanding the biochemical functions and physiological relevance of microbial virulence factors and antibiotic resistance. • Derivation of mechanistic approaches to problem-solving in molecular and cellular biomedical science.
Individuals who successfully complete the course will have developed the ability to:
• Demonstrate practical dexterity in the commonly employed and more advanced practical techniques of molecular and cellular microbiology • Exercise theoretical and practical knowledge and competence required for employment in a variety of biomedical environments • Identify appropriate methodology during experimental planning • Interpret and present scientific data • Interrogate relevant scientific literature and develop research plans • Recognise the importance of justifying expenditure (cost and time) during experimental planning • Recognise potential methodological failings and strategise accordingly • Perform novel laboratory-based research, and exercise critical scientific thought in the interpretation of findings • Write and defend research reports, which appraise the results of laboratory based scientific study • Communicate effectively through writing, oral presentations and IT to facilitate further study or employment in molecular, cellular and physiological science • Exercise a range of transferable skills
This will be achieved by providing:
• A course of lectures, seminars, tutorials and technical workshops. The programme is underpinned by the breadth and depth of scientific expertise in the participating department. • Hands-on experience of a wide repertoire of scientific methods • Two research projects • Training in core transferable skills
Candidates are expected to hold a good first degree (upper second class or better) from a UK university or an equivalent qualification if obtained outside the UK.
Please visit the course website for more information about how to apply, and for more information about the various streams of specialism which run within the course.
Early application is strongly advised. Please note that while applications can be considered after receipt of one recent reference, two will be required as standard for confirmation of acceptance by College.
----------------------------------------------- Home, EU and Overseas applicants hoping to start this course in October 2017 will be eligible to apply for the Faculty of Medicine Dean's Master’s Scholarships. This scheme offers a variety of awards, including full tuition payment and a generous stipend. For more information, please visit http://www.imperial.ac.uk/medicine/study/postgraduate/deans-masters-scholarships/. Applications for 2017 are not yet open (do check the website again early in the new year).