Xi’an Jiaotong-Liverpool University Featured Masters Courses
University of East London Featured Masters Courses
University of Portsmouth Featured Masters Courses
University of the Arts London Featured Masters Courses
Manchester Metropolitan University Featured Masters Courses

MDP in Biomedical Sciences: Medicinal and Radiopharmaceutical Chemistry

    University of Turku Master's Programmes Logo
  • Study Type

    Full time available

  • Subject Areas

    Chemistry

    Medicine

  • Start Date

    August

  • Course Duration

    2 academic years

  • Course Type

    Other

  • Course Fees

    Free for citizens of EU/EEA countries or Switzerland.

    For other countries, please visit website for details.

  • Last Updated

    15 October 2019

The Master's Degree Programme in Biomedical Sciences – Medicinal and Radiopharmaceutical Chemistry specialisation track equips you with theoretical and practical skills in drug screening, identification, design and targeting.

How to find, identify, design and target new drugs?

The programme provides you with strong knowledge on one or more of the following topics that covers the chemistry of drug development from slightly different perspectives: bio-organic chemistry, radiopharmaceutical chemistry and natural compound chemistry. In addition, you will learn to master the state-of-the-art methods needed for the full identification of drug molecules and for their quantitation from different types of tissues and metabolite mixtures. Our approach gives you strong hands-on knowledge on medicinal chemistry, since practical laboratory work forms the soul of our programme.

ACADEMIC EXCELLENCE & EXPERIENCE

Our approach on medicinal and radiopharmaceutical chemistry is a unique combination of research areas that are closely related, but that require different type of expertise. All of the three options are represented by well-established, top of the line research groups: Bioorganic GroupRadiopharmaceutical Chemistry Group, and Natural Chemistry Research Group.

The main target in studies of Bio-organic Chemistry is to master the key concepts of organic reactions, stereochemistry and physical organic chemistry. This way the student can design and execute organic syntheses and understand chemical biology. The Bioorganic Group is specialized into the synthesis of biopolymers (oligonucleotides, oligosaccharides and peptides), their interaction mechanisms at the molecular level and to the application of this knowledge into solving medicinal problems.

Students of Radiopharmaceutical Chemistry can specialize into radiochemistry, i.e. the synthesis and use of short-lived, isotopically labelled positron emitting organic tracers. These tracers are used in positron emission tomography (PET) that enables imaging of biochemical processes in vivo in both health and disease. The synthesis of radiotracers involves both low molecular weight small molecules as well as macromolecules, typically peptides, proteins and their fragments. Teaching of radiopharmaceutical chemistry takes place in close collaboration with the Turku PET Centre, a National Institute jointly owned by the University of Turku, the Åbo Akademi University and the Hospital District of Southwestern Finland.

With Natural Compound Chemistry you learn to master numerous chromatographic and mass spectrometric techniques together with other methods used for characterization and activity measurement of plant-derived biomolecules. The Natural Chemistry Research Group is specialized into the screening of the plant kingdom for bioactive molecules, especially large polyphenols such as ellagitannins. The screening phase can be accompanied by purification of active substances and measuring their structure/activity relationships, or developing new activity methods.

The facilities of Medicinal and Radiopharmaceutical Chemistry are state-of-the-art. We have direct access to the Turku PET Centre preclinical and clinical groups. The PET Centre has four cyclotrons for radionuclide production and 25 hot cells for radiotracer synthesis. At the Department of Chemistry we have recently updated NMR facilities with modern 500 and 600 MHz magnets with cryo-probes that facilitate operation at low drug concentrations. We have direct access to UPLC-MS/MS instruments with both triple quadrupole and high-resolution mass spectrometry detectors. An efficient ECD spectrometer complements the equipment needed for the accurate identification of the produced and purified drug candidates. To know how to master these equipment and techniques is a true advantage to the chemist who graduates from our programme.

CAREER OPTIONS

Competence Description

After completing the studies, depending on your specialization, you will

  • know how to design and execute multistep synthesis routes to produce organic compounds
  • know the special requirements to work in the radiopharmaceutical chemistry laboratory
  • know the basics of bioimaging
  • know how to design and execute synthesis routes for compounds used in bioimaging
  • know how to isolate and purify organic compounds
  • know how to characterize structures of organic compounds
  • understand how reactivity and bioactivity is related both to the structure and reaction conditions
  • know the chemical properties, functionality and biological significance of biopolymers and their structural units
  • know the classes of plant bioactive compounds, their biosynthesis routes and chemical properties and their most important structure/activity-relationships
  • be able to use and develop liquid chromatographic and mass spectrometric methods
  • know how to measure different types of bioactivities for pure compounds and compound mixtures, and to develop new types of activity methods

Job Options

Medicinal and Radiopharmaceutical Chemistry track has close connections to the pharma industry at the Turku region and international collaborative networks. These provide the students with opportunities to do the Master’s Laboratory Project in their facilities or in collaboration. They may offer internships and job opportunities for the graduates as well.

You will be equipped with skills that provide you with multiple career options. You will be able to join the industry in Finland or abroad, or to enter the public sector, for example, in various authoritative duties.

The studies in Medicinal and Radiopharmaceutical Chemistry provide excellent possibilities for a career in life sciences. For example, you can:

  • continue as a postgraduate student to pursue a career as a scientist
  • work in industry as a researcher or quality manager
  • work in a core facility management taking care of e.g. the mass spectrometers
  • work in science administration nationally or internationally
  • work in hospital research laboratories
  • be a product manager or a project coordinator

Career in Research

The Master of Science degree completed in the Programme qualifies the graduates for PhD studies in Turku, elsewhere in Finland or universities worldwide.

Graduates from the programme are eligible to apply for a position in the University of Turku Graduate School, UTUGS. The Graduate School consists of doctoral programmes, which cover all disciplines and doctoral candidates of the University.

Together with the doctoral programmes, the Graduate School provides systematic and high quality doctoral training. UTUGS aims to train highly qualified experts with the skills required for both professional career in research and other positions of expertise.

Several doctoral programmes at University of Turku are available for graduates:


Visit the MDP in Biomedical Sciences: Medicinal and Radiopharmaceutical Chemistry page on the University of Turku website for more details!

Loading...

Loading...

Loading...

Loading...


Enquire About This Course

Recipient: University of Turku

* required field

Please correct the errors indicated below to send your enquiry


Your enquiry has been emailed successfully