We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments.
As a student you will be registered with a University research institute, for many this is the Institute for Cellular Medicine (ICM). You will be supported in your studies through a structured programme of supervision and training via our Faculty of Medical Sciences Graduate School.
We undertake the following areas of research and offer MPhil, PhD and MD supervision in:
Newcastle hosts one of the most comprehensive organ transplant programmes in the world. This clinical expertise has developed in parallel with the applied immunobiology and transplantation research group. We are investigating aspects of the immunology of autoimmune diseases and cancer therapy, in addition to transplant rejection. We have themes to understand the interplay of the inflammatory and anti-inflammatory responses by a variety of pathways, and how these can be manipulated for therapeutic purposes. Further research theme focusses on primary immunodeficiency diseases.
There is strong emphasis on the integration of clinical investigation with basic science. Our research include:
We also research the effects of UVR on the skin including mitochondrial DNA damage as a UV biomarker.
This area emphasises on translational research, linking clinical- and laboratory-based science. Key research include:
Focus is on applied research and aims to underpin future clinical applications. Technology-oriented and demand-driven research is conducted which relates directly to health priority areas such as:
This research is sustained through extensive internal and external collaborations with leading UK and European academic and industrial groups, and has the ultimate goal of deploying next-generation diagnostic and therapeutic systems in the hospital and health-care environment.
There is a number of research programmes into the genetics, immunology and physiology of kidney disease and kidney transplantation. We maintain close links between basic scientists and clinicians with many translational programmes of work, from the laboratory to first-in-man and phase III clinical trials. Specific areas:
We have particular interests in:
Novel non-invasive methodologies using magnetic resonance are developed and applied to clinical research. Our research falls into two categories:
Our studies cover a broad range of topics (including diabetes, dementia, neuroscience, hepatology, cardiovascular, neuromuscular disease, metabolism, and respiratory research projects), but have a common theme of MR technical development and its application to clinical research.
We focus on connective tissue diseases in three, overlapping research programmes. These programmes aim to understand:
This research theme links with other local, national and international centres of excellence and has close integration of basic and clinical researchers and hosts the only immunotherapy centre in the UK.
Genetic approaches to the individualisation of drug therapy, including anticoagulants and anti-cancer drugs, and in the genetics of diverse non-Mendelian diseases, from diabetes to periodontal disease, are a focus. A wide range of knowledge and experience in both genetics and clinical sciences is utilised, with access to high-throughput genotyping platforms.
Our scientists and clinicians use in situ cellular technologies and large-scale gene expression profiling to study the normal and pathophysiological remodelling of vascular and uteroplacental tissues. Novel approaches to cellular interactions have been developed using a unique human tissue resource. Our research themes include:
We also have preclinical molecular biology projects in breast cancer research.
We conduct a broad range of research activities into acute and chronic lung diseases. As well as scientific studies into disease mechanisms, there is particular interest in translational medicine approaches to lung disease, studying human lung tissue and cells to explore potential for new treatments. Our current areas of research include:
Our research projects are concerned with the harmful effects of chemicals, including prescribed drugs, and finding ways to prevent and minimise these effects. We are attempting to measure the effects of fairly small amounts of chemicals, to provide ways of giving early warning of the start of harmful effects. We also study the adverse side-effects of medicines, including how conditions such as liver disease and heart disease can develop in people taking medicines for completely different medical conditions. Our current interests include: environmental chemicals and organophosphate pesticides, warfarin, psychiatric drugs and anti-cancer drugs.
Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.
Gain the essential skillsets as a nutritionist to help improve people’s health and well-being in the context of the malnutrition, obesity, metabolic response to injury and chronic disease.
This was the first MSc in Clinical Nutrition to be established in the UK and has gained an international reputation, attracting students from around the world. You will consider the patient’s journey from birth to extreme age in the context of the metabolic response to injury or to chronic disease. The course is designed for all members of nutrition support teams and is also suitable for students who wish to pursue clinically-based nutrition research.
After establishing a firm foundation in physiology and the biochemistry of nutrition, this course will cover the nutritional management for clinical conditions such as gastro-enteral problems, long-term disablement and intensive care. It also includes a focus on nutrition support in paediatric, adult, older adult and critically ill patients.
This course is perfect for nutrition support teams or those who want to pursue a career or a doctorate in clinically-based nutrition. The course will provide an important insight into contemporary developments in clinical nutrition for a wide range of healthcare professionals.
You will have access to our state-of-the art facilities and excellent laboratories including a food lab complete with sensory analysis tasting booths and specialist laboratories for physiology, microbiology and computing.
Please note this programme does not lead to a qualification in the UK as a registered Dietitian. It is an accredited course with the Association for Nutrition, and does enable you to become a registered nutritionist, once you have complete two years in the nutrition field.
This course is accredited by the Association for Nutrition.
We offer a diverse range of modules to build your knowledge and enable you to focus on topics that interest you. Recent examples of these topics have included: macronutrient and micronutrient metabolism in health and disease, nutrient digestion and absorption and gastrointestinal disease, nutritional support in paediatric, adult, older adult and critically ill patients, the effect of disease on nutrition status.
Research areas that are also included in the programme are dietary management strategies in women with polycystic ovary syndrome; the role of brain–gut interaction in obesity, eating disorders, and irritable bowel syndrome; the role of the enteric nervous system in known intestinal diseases; vitamin E status in health and disease; the role of microbiota in food and nutritional systems; food bioactives for a healthy gut, brain and vascular system; the regulation of insulin secretion and glucose metabolism in health and diabetes.
Here are examples of the modules:
Nutritionist (public sector, private commercial or independent), public health nutritionist, academia research/teaching, commercial research, NHS (various roles) and local and central government (roles in policy and health promotion). In addition, many students are already health professionals and study the course as part of their career development and specialisation.
This accredited course co-ordinates specialist contributions from clinical scientists, consultants, clinical networks and departments. It uses facilities from Newcastle University and Newcastle Hospitals NHS Foundation Trust. The course offers specialist pathways in medical physics and physiological sciences and is available to the healthcare science workforce and through competitive national recruitment.
This specialist course runs under the NHS Scientist Training Programme (STP) and is accredited by the National School for Healthcare Science Accreditation Unit. Combining academic and workplace learning, the formal teaching element is delivered through structured residential teaching blocks and online study.
There are two pathways.
Medical Physics offers specialisms in:
-Radiation safety physics
-Imaging with ionising radiation
-Imaging with non-ionising radiation
Physiological Sciences offers specialisms in:
-Respiratory and sleep science
HOW TO APPLY:
To study on these courses you will need to apply through the National School of Healthcare Science - Scientist Training Programme.
The site includes frequently asked questions about application and eligibility.
The Faculty of Medical Sciences website has further information about Medical Physics and Physiological Sciences pathways.