This new and innovative course builds upon the integrated nature of the School of Dentistry’s clinical and basic science divisions, and aims to prepare future researchers, from scientific or clinical backgrounds for research careers based in addressing oral health needs. You’ll gain a thorough background in oral sciences, the investigative, cutting edge technologies that enable oral scientific discovery and the necessary training in research governance and rigour. All areas of translational research pathways will be addressed, including aspects of commercialisation which will be taught through the Leeds University Business School (LUBS). Disease focused modules provide opportunities for in-depth exploration with research experts in the fields of Cancer, Musculoskeletal and Oral and systemic disease links.
Our teaching staff includes world leading experts with track records in translating research discoveries into novel healthcare products and practices. Student integration within the wider Dental school will be facilitated by undertaking recently updated modules shared with students from other MSc programmes.
Aimed at dental and biosciences graduates, the course will facilitate a career path focussed on oral research and its translation into positive impacts on health.
The programme will:
Teaching will be split between the Dental school on the main campus and the Wellcome Trust Brenner Building (WTBB) at the St James’s University Hospital. The WTBB is a modern purpose built research facility, housing cutting edge facilities in imaging, tissue and microbiological culture and next generation sequencing technologies. On the main campus students can benefit from all the expertise, facilities (such as the Leeds Dental Translational and Clinical Research Unit) and support provided by the Dental school.
Our course emphasises student directed and multidisciplinary learning. Teaching methods include lectures, seminars and workshops, complemented by e-learning and will be delivered by research active scientists and clinicians with additional input from industrial partners and Leeds University Business School (LUBS) academics.
Summative assessment will provide you with on-going feedback on your depth of subject knowledge and skills. Assessment methods for formative and summative assessment will include oral and poster presentations, unseen examinations and literature reviews. Exercises to identify research questions formulate research plans and prepare mock applications for funding and ethical/ governance approvals will also contribute to assessment.
You will gain insight into all stages of translational research, preparing you for a career working across multi-disciplinary teams within research and innovation management. The course aims to enhance your career prospects of securing PhD studentship positions, whether that be in pre-clinical or clinical research.
The innovation management in practice module enables you to learn about the commercial aspects of translational research. It may be that you want to go into the oral healthcare industry, so knowledge of business skills will be a useful transferable skill.
You may want to go into academic teaching positions within your own country; this MSc will provide the knowledge required to teach oral biology at undergraduate level.
This research-based course has a taught component that is the same as an MSc. It provides a springboard into a career that involves a working knowledge of scientific research.
The course is designed for graduates with a BSc in the life sciences or other science disciplines, and for intercalating and fully qualified MBBS or BDS students. It can be taken either as a stand-alone qualification or as an entry route onto a PhD or MD.
The taught component of the course includes subject-specific content in the area of translational medicine and therapeutics. You have the flexibility to develop your own bespoke course by selecting additional, complementary modules. You will also participate in training in general research principles, and other professional and key skills.
Subject-based modules in translational medicine and therapeutics provide the opportunity to learn about the development and evaluation of new medicines and to develop skills in translational research relating to therapeutics. Teaching and supervision is provided by both university-based academics and experts from the pharmaceutical industry.
Your research project comprises the major element of the course. This project will involve 24 weeks of research in an area of translational medicine and therapeutics under the supervision of an expert academic researcher in the field.
The course allows you to experience an internationally competitive research area, predominantly in academia but also potentially in industry.
Translational Medicine and Therapeutics MRes is closely linked to a suite of MRes courses that you may also be interested in:
Our Medical Sciences Graduate School is dedicated to providing you with information, support and advice throughout your research degree studies. We can help and advise you on a variety of queries relating to your studies, funding or welfare.
Our Research Student Development Programme supports and complements your research whilst developing your professional skills and confidence.
You will make an on-going assessment of your own development and training needs through personal development planning (PDP) in the ePortfolio system. Our organised external events and development programme have been mapped against the Vitae Researcher Development Framework to help you identify how best to meet your training and development needs.
Translational Cancer Medicine enables you to gain detailed knowledge and understanding of research methods applied to rational drug design, clinical study design, molecular and cell biology, tumour immunology, genetics and cancer imaging. You'll gain practical experience through two six-month laboratory rotations.
The Translational Cancer Medicine MRes study pathway offers unique opportunities for you to join experienced research teams and work on particular projects from the outset. This course will allow you to develop an in-depth understanding of research methods, and of how theoretical academic studies and skills relate to research projects.
You will explore Fundamentals of Translational Cancer Medicine, providing you with advanced knowledge and skills to conceptualise, design, conduct and critically appraise specialist research. You will gain hands on research experience in two six month lab projects.
We use lectures, seminars and group meetings to deliver most of the modules on the course.
On average teaching consists of:
You will also be expected to undertake a significant amount of independent study.
Typically, 1 credit equates to ten hours of work.
Throughout the year, you will also attend literature reviews and journal clubs that the labs/departments organise, as well as any other internal or external seminars deemed relevant to your projects/assignments.
The primary method of assessment for this course is a combination of written essays, a thesis (research report), a presentation/Q&A session regarding the research report and a draft of a scientific paper.
The study time and assessment methods detailed above are typical and give you a good indication of what to expect. However, they are subject to change.
Occupational health clearance will be required for some of the projects.
Future PhD studies. Clinical and non-clinical academic careers in cancer medicine.
This programme will provide a world-class education for advanced training in translational research, from preclinical discovery through to first-time-in-man studies in human and clinical trials in healthy volunteers and patients across neurology and neurodegeneration.
The programme combines theoretical and practical teaching on both the breadth of, and complexity in conducting clinical research. Topics include clinical pharmacology, pharmacokinetics, research governance, statistics and the fundamental principle for using the correct enabling technologies within the context of medical research and drug development.
Students undertake modules to the value of 180 credits.
The programme consists of three core modules (60 credits), and a dissertation/report (120 credits).
There are no optional modules for this programme.
All students undertake a research project which culminates in a dissertation of 15,000 words.
Teaching and learning
The programme will combine lectures, workshops and tutorials. Practicals will focus on the role of surrogate markers and emerging technologies in drug development e.g. preclinical discovery, first-time-in-man studies, and early phase clinical trials in healthy volunteers and patients. Assessment is through short answer unseen examinations, coursework and presentations..
Further information on modules and degree structure is available on the department website: Translational Neurology MRes
The programme is designed to cater to graduates in medicine and biomedical sciences who wish to gain valuable training in clinical research before embarking on a clinical PhD programme, medical training, or professional work in clinical trials. The successful completion of the MRes may also enhance opportunities for graduates to enter medical school or for MBBS graduates to progress to specialist medical training.
Whatever your chosen career pathway, the MRes in Translational Neurology will equip graduates to either get a first step on the ladder, change career directions or help them become more experienced with a specific expertise.
The programme is delivered by the UCL Institute of Neurology, a specialist postgraduate institute and a worldwide centre of excellence in clinical research across neurological diseases, including movement disorders (e.g. Parkinson’s disease), multiple sclerosis, neuro-inflammation, epilepsy, stroke, cognitive dysfunction, Alzheimer’s disease and other dementias.
Students will be taught by experts in the field and have the opportunity to network with internationally recognised opinion leaders in neurology and neurodegeneration.
Dementia (including a raft of neurodegenerative diseases such as Alzheimer’s Disease) has recently become the leading cause of death in the UK. Stem cells are a novel and relatively young branch of scientific research that hold the potential for not only therapies but to be able to accurately model these distinctly human diseases.
This unique programme will offer students real-world perspectives from patients, carers, scientists and a range of health care professionals including world-leading experts on the impact of neurological diseases.
This programme offers cutting edge translational neuroscience focused on stem cells, neurodegenerative diseases, regeneration and models (both animal and cell). Furthermore the inclusion of patients and importantly their carers and the real-life impacts of these diseases on individuals will be a common thread running throughout this programme making it truly unique and exceptionally novel.
This programme is designed for medical and/or scientific professionals and aims to introduce students to the fields of neurodegenerative diseases, stem cells, industry and emerging therapeutic opportunities in regenerative / translational neurology. Overall students will gain the knowledge and understanding of the clinical, real-life impact and scientific realities of these fields and thus advance their own learning and be able to carry this forward into their future careers.
Therefore students will be introduced to a range of topics as they progress through the programme from introducing the basic anatomy, structure and development of the central nervous system, a critical understanding of stem cells including sources, locations and roles, an introduction to multiple neurodegenerative diseases (such as Alzheimer’s, Motor Neurone Disease and Parkinson’s disease), from both clinical and patient angles, before being introduced to in vitro and in vivo modelling of these diseases, neuroimaging techniques, stem cells and industry.
This part-time, fully online programme will support the need for up-to-date knowledge, skills and theory in a wide variety by the use of not only world leading clinical and scientific experts but also by using the real-life impacts as viewed by patients, the people who care for them and the frontline health professionals. All of this expertise will be presented utilising a range of techniques including: online lectures, practical studies, directed readings and other video and audio resources.
Discussion boards will provide directed assessment tasks while input from expert guest lecturers and tutors offer students opportunity for collaborative critical discourse and debate of current issues.
Within the programme, students can progress from Postgraduate Certificate (60 credits), to Postgraduate Diploma (120credits) and to Master of Science degrees (180 credits) as they successfully complete the required number of credits for each level and can therefore stop at any stage or continue onwards depending on their situation.
Composed of 4 core courses to provide the fundamental foundations for the Diploma and MSc but can also be taken as a self-contained PGCert. It will cover fundamental areas including key basic research skills (such as how to critically evaluate scientific manuscripts, as well as a basic understanding of statistics) whilst introducing students to the central nervous system, its basic anatomy and development and stem cells. In parallel students would cover an introduction to neurodegenerative diseases (that would include Alzheimer’s Disease, Parkinson’s Disease and Motor Neurone Disease) before being introduced to in vitro and in vivo modelling of these diseases. Finally students would also learn about neuroimaging and its potential roles for scientific research.
Expands on the PGCert courses as well as introducing greater depth to novel areas such as the roles of pharma and industry with respect to stem cells. A proportion of the Diploma credits are elective and students will be assisted in choosing appropriate options from across the broad spectrum available from Edinburgh University that are relevant to their own situation, employment and career goals.
Students have the opportunity to explore a specialist area from within the broad spectrum of stem cells, regeneration and translational neuroscience in the form of either a dissertation, or, a structured project (the student would themselves have to source this if desired), which would aim to deliver a ‘real world’ project with a direct impact for an employer, organisation or personal goal. A third option available for students is a choice of 60 fully taught credits.
The minimum recommended time for completion of the full Masters programme is three years, and the maximum time for completion is six years. The Certificate and Diploma can be completed on a pro rata basis.
Postgraduate Professional Development (PPD)
Postgraduate Professional Development (PPD) is aimed at working professionals who want to advance their knowledge through a postgraduate-level course(s), without the time or financial commitment of a full Masters, Postgraduate Diploma or Postgraduate Certificate.
You may take a maximum of 50 credits worth of courses over two years through our PPD scheme. These lead to a University of Edinburgh postgraduate award of academic credit. Alternatively, after one year of taking courses you can choose to transfer your credits and continue on to studying towards a higher award on a Masters, Postgraduate Diploma or Postgraduate Certificate programme.
Although PPD courses have various start dates throughout a year you may only start a Masters, Postgraduate Diploma or Postgraduate Certificate programme in the month of September. Any time spent studying PPD will be deducted from the amount of time you will have left to complete a Masters, Postgraduate Diploma or Postgraduate Certificate programme.
Potential career paths, exits routes and employers are very diverse and depend on the students chosen carer. For students working in a clinical environment this programme would offer them career advancement/specialism within their clinical setting.
For students coming from a scientific background there is the opportunity to improve carer prospects in laboratory research settings or alternatively to help in progressing to a PhD.
Our Master of Research (MRes) in Translational Medicine will give you the research skills you need to use state-of-the-art biotechnologies to rapidly translate disease research into improved clinical healthcare.
Our understanding of the molecular basis of disease and drug mechanisms has improved dramatically in recent years, yet there is a distinct shortage of individuals able to apply this knowledge into effective clinical benefit. The core aim is to train the next generation of scientists able to 'fast-track' biological and scientific data into advanced therapies and diagnostics tools.
With advances in technology, graduates are faced with heightened expectations to conduct effective bioscience research. Employers demand skillsets with biological, medical, physical and computational characteristics, and our course is designed to provide this breadth of training.
You will learn omics skills and techniques such as genetics, genomics, transcriptomics, proteomics and metabolomics. Our training in metabolomic techniques is novel for a UK course, while our teaching on the integration of different omic platforms and data in a systems medicine strategy is also unique.
The MRes course consists of four taught units - which together make up the PGCert - plus an extended 35-week project that can be undertaken at the University, the Manchester Cancer Research Centre or a teaching hospital in Greater Manchester.
You can choose from a range of projects covering areas such as the use of gene expression profiling, proteomics, metabolomics, stem cell research, tissue culture or pharmacogenetics in the biology of cancer, cardiovascular disease, infectious diseases, stroke or diabetes.
Completing our course will open up a route into PhD research. You may also pursue a career in academia or the pharmaceutical or biotechnology industries, or as a clinical academic.
Extensive research experience
The 35-week research project for the MRes award offers the chance to conduct ambitious projects in areas such as cancer, cardiovascular disease, inflammation, mental health, infectious diseases, stroke or diabetes, using methods such as stem cell research, proteomics, metabolomics, tissue culture or pharmacogenetics.
Integrated focus on key topics
Our course has a strong and integrated focus on genetics, genomics, proteomics and metabolomics biotechnology and data interpretation, which are strengths within Manchester and are identified as core areas of bioscience growth.
Teaching comprises four taught units delivered using a variety of face-to-face, workshop and e-learning approaches and an extended 35-week research project for the MRes award.
Examples of research projects include the following.
Find out more by visiting the postgraduate teaching and learning page.
More than 50% of our graduates progress into PhD research at Manchester or other universities such as Cambridge, Imperial College London, Newcastle, Glasgow, Liverpool and Bristol.
Around 15% pursue a career in the pharmaceutical or biotechnology industry in the UK or abroad.
Approximately 25% are intercalating medics who complete their medical education. An estimated 10% pursue an undergraduate medical degree.
The Department of Oncology and the Department for Continuing Education’s CPD Centre offer a part-time MSc in Experimental and Translational Therapeutics that brings together some of Oxford's leading clinicians and scientists to deliver an advanced modular programme designed for those in full-time employment, both in the UK and overseas.
The Programme draws on the world-class research and teaching in experimental therapeutics at Oxford University and offers a unique opportunity to gain an understanding of the principles that underpin clinical research and to translate this into good clinical and research practice.
Visit the website https://www.conted.ox.ac.uk/about/msc-in-experimental-therapeutics
If your application is completed by this January deadline and you fulfil the eligibility criteria, you will be automatically considered for a graduate scholarship. For details see: http://www.ox.ac.uk/admissions/graduate/fees-and-funding/graduate-scholarships.
The MSc in Experimental and Translational Therapeutics is a part-time course consisting of six modules and a research project and dissertation. The programme is normally completed in two to three years. Students are full members of the University of Oxford and are matriculated as members of an Oxford college.
The modules in this programme can also be taken as individual short courses. It is possible to transfer credit from up to three previously completed modules into the MSc programme, if the time elapsed between commencement of the accredited module(s) and registration for the MSc is not more than two years.
- The Structure of Clinical Trials and Experimental Therapeutics
- Drug Development, Pharmacokinetics and Imaging
- Pharmacodynamics, Biomarkers and Personalised Therapy
- Adverse Drug Reactions, Drug Interactions, and Pharmacovigilance
- How to do Research on Therapeutic Interventions: Protocol Preparation
- Biological Therapeutics
The aim of the MSc programme is to provide students with the necessary training and practical experience to enable them to understand the principles that underpin clinical research, and to enable them to translate that understanding into good clinical and research practice.
By the end of the MSc programme, students should understand the following core principles:
- Development, marketing and regulations of drugs
- Pharmaceutical factors that affect drug therapy
- Pharmacokinetics, pharmacogenetics and pharmacodynamics
- Adverse drug reactions, drug interactions, and pharmacovigilance
- Designing phase I, II and III clinical trials for a range of novel therapeutic interventions (and imaging agents).
- Application of statistics to medicine
- Laboratory assays used to support trial end-points
- Use of non-invasive imaging in drug development
- Application of analytical techniques
By the end of the programme, students should be equipped to:
- demonstrate a knowledge of the principles, methods and techniques for solving clinical research problems and translate this into good clinical and research practice
- apply skills gained in techniques and practical experience from across the medical and biological sciences
- develop skills in managing research-based work in experimental therapeutics
- carry out an extended research project involving a literature review, problem specification and analysis in experimental therapeutics and write a short dissertation
Guidance from the UK Royal College of Physician's Faculty of Pharmaceutical Medicine
The Faculty have confirmed that if enrolled for Pharmaceutical Medicine Specialty Training (PMST), trainees may be able to use knowledge provided by Experimental Therapeutics modules to cover aspects of a module of the PMST curriculum. Trainees are advised to discuss this with their Educational Supervisor.
Experimental Therapeutics modules may also be used to provide those pursuing the Faculty's Diploma in Pharmaceutical Medicine (DPM) with the necessary knowledge required to cover the Diploma syllabus. Applicants for the DPM exam are advised to read the DPM syllabus and rules and regulations.
Members of the Faculty of Pharmaceutical Medicine who are registered in the Faculty's CPD scheme can count participation in Experimental Therapeutics modules towards their CPD record. Non-members may wish to obtain further advice about CPD credit from their Royal College or Faculty.
To complete the MSc, students need to:
Attend the six modules and complete an assessed written assignment for each module.
Complete a dissertation on a topic chosen in consultation with a supervisor and the Course Director.
The dissertation is founded on a research project that builds on material studied in the taught modules. The dissertation should normally not exceed 15,000 words.
The project will normally be supervised by an academic supervisor from the University of Oxford, and an employer-based mentor.
The following are topics of dissertations completed by previous students on the course:
- The outcomes of non-surgical management of tubal pregnancy; a 6 month study of the South East London population
- Analysis of the predictive and prognostic factors of outcome in a cohort of patients prospectively treated with perioperative chemotherapy for adenocarcinoma of the stomach or of the gastroesophageal junction
- Evolution of mineral and bone disorder in early Chronic Kidney Disease (CKD): the role of FGF23 and vitamin D
- Survey of patients' knowledge and perception of the adverse drug reporting scheme (yellow cards) in primary care
- The predictive role of ERCC1 status in oxaliplatin based Neoadjuvant for metastatic colorectal cancer (CRC) to the liver
- Endothelial Pathophysiology in Dengue - Dextran studies during acute infection
- Literature review of the use of thalidomide in cancer
- An investigation into the phenotypical and functional characteristics of mesenchymal stem cells for clinical application
- Identification of genetic variants that cause capecitabine and bevacizumab toxicity
- Bridging the evidence gap in geriatric medicines via modelling and simulations
The class-based modules will include a period of preparatory study, a week of intensive face-to-face lectures and tutorials, followed by a period for assignment work. Attendance at modules will be a requirement for study. Some non-classroom activities will be provided at laboratory facilities elsewhere in the University. The course will include taught material on research skills. A virtual learning environment (VLE) will provide between-module support.
The taught modules will include group work, discussions, guest lectures, and interaction and feedback with tutors and lecturers. Practical work aims to develop the students' knowledge and understanding of the subject.
Find out how to apply here - http://www.ox.ac.uk/admissions/graduate/applying-to-oxford
Lead academic: Dr Jonathan Wood
Translational Neuroscience looks at how laboratory research relating to brain structure and function informs the development of new therapies for diseases of the nervous system.
Combining the research strengths from the Faculty of Medicine, Dentistry and Health and the Faculty of Science, leading international basic and clinical scientists will provide an innovative and progressive programme. You’ll study basic neurobiology and molecular biology through to neuroimaging and applied clinical practice.
The MSc will provide you with up-to-date knowledge of advances in the field, research experience with internationally renowned research groups and transferable skills to provide a springboard for your future career.
You’ll be based in teaching hospitals that serve a population of over half a million people and refer a further two million. We also have close links with the University’s other health-related departments.
Our research funding comes from many sources including the NIHR, MRC, BBSRC, EPSRC, the Department of Health, EU, and prominent charities such as the Wellcome Trust, ARC, YCR, Cancer Research UK and BHF. Our partners and sponsors include Novartis, GlaxoSmithKline, Pfizer, Astra Zeneca and Eli Lilly.
You’ll also benefit from our collaboration with the Department of Biomedical Sciences.
Classes are kept small (15–20 students) to make sure you get the best possible experience in laboratories and in clinical settings.
We have a state-of-the-art biorepository and a £30m stem cell laboratory. The Sheffield Institute of Translational Neuroscience (SITraN) opened in November 2010. We also have microarray, genetics, histology, flow cytometry and high-throughput screening technology, and the latest equipment for bone and oncology research.
At our Clinical Research Facility, you’ll be able to conduct studies with adult patients and volunteers. The Sheffield Children’s Hospital houses a complementary facility for paediatric experimental medical research.
If your course involves a significant risk of exposure to human blood or other body fluids and tissue, you’ll need to complete a course of Hepatitis B immunisation before starting. We conform to national guidelines that are in place to protect patients, health care workers and students.
A 20-week Research Project will be undertaken in the summer term.
Lectures, seminars, tutorials, laboratory demonstrations, computer practicals and student-led group work.
Assessment is primarily by written assignments and coursework, although there are some written examinations and oral presentations. The research project is assessed by a thesis and presentation.
Upon graduation, the student is expected
Further information about the studies on the Master's programme website.
The TRANSMED studies are built upon three themes:
Development of research skills
The curriculum includes courses in statistics and the R programming language, bioinformatics, research ethics, and principles of clinical investigation. You will also practice the writing of research proposals and develop your skills in research methodologies during a training period in a research group.
Studies in human disease
The courses range from normal human physiology and anatomy, and basic biomedical courses, to more advanced studies covering topics pertinent to the specialist option. You supplement these studies with clinical rounds, during which you have the opportunity to study selected patient cases in hospital wards, under the supervision of a clinician mentor.
Development of communication skills
Communication skills are promoted through interactive approaches and discussions, groupwork, team-based learning and oral presentations. In TRANSMED you will have opportunities for direct interactions with medical students, scientists and clinical teachers to enable you to practice and adopt interdisciplinary communication skills. At the end of the course of study, your communication skills will be evaluated in a Research Proposal Exam, during which you will orally present and defend your research plan to expert examiners.