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Masters Degrees (Stem Cells)

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. Dementia (including a raft of neurodegenerative diseases such as Alzheimer’s Disease) has recently become the leading cause of death in the UK. Read more

Dementia (including a raft of neurodegenerative diseases such as Alzheimer’s Disease) has recently become the leading cause of death in the UK. Stem cells are a novel and relatively young branch of scientific research that hold the potential for not only therapies but to be able to accurately model these distinctly human diseases.

This unique programme will offer students real-world perspectives from patients, carers, scientists and a range of health care professionals including world-leading experts on the impact of neurological diseases.

This programme offers cutting edge translational neuroscience focused on stem cells, neurodegenerative diseases, regeneration and models (both animal and cell). Furthermore the inclusion of patients and importantly their carers and the real-life impacts of these diseases on individuals will be a common thread running throughout this programme making it truly unique and exceptionally novel.

This programme is designed for medical and/or scientific professionals and aims to introduce students to the fields of neurodegenerative diseases, stem cells, industry and emerging therapeutic opportunities in regenerative / translational neurology. Overall students will gain the knowledge and understanding of the clinical, real-life impact and scientific realities of these fields and thus advance their own learning and be able to carry this forward into their future careers.

Therefore students will be introduced to a range of topics as they progress through the programme from introducing the basic anatomy, structure and development of the central nervous system, a critical understanding of stem cells including sources, locations and roles, an introduction to multiple neurodegenerative diseases (such as Alzheimer’s, Motor Neurone Disease and Parkinson’s disease), from both clinical and patient angles, before being introduced to in vitro and in vivo modelling of these diseases, neuroimaging techniques, stem cells and industry.

Online learning

This part-time, fully online programme will support the need for up-to-date knowledge, skills and theory in a wide variety by the use of not only world leading clinical and scientific experts but also by using the real-life impacts as viewed by patients, the people who care for them and the frontline health professionals. All of this expertise will be presented utilising a range of techniques including: online lectures, practical studies, directed readings and other video and audio resources.

Discussion boards will provide directed assessment tasks while input from expert guest lecturers and tutors offer students opportunity for collaborative critical discourse and debate of current issues.

Programme structure

Within the programme, students can progress from Postgraduate Certificate (60 credits), to Postgraduate Diploma (120credits) and to Master of Science degrees (180 credits) as they successfully complete the required number of credits for each level and can therefore stop at any stage or continue onwards depending on their situation.

Postgraduate Certificate

Composed of 4 core courses to provide the fundamental foundations for the Diploma and MSc but can also be taken as a self-contained PGCert. It will cover fundamental areas including key basic research skills (such as how to critically evaluate scientific manuscripts, as well as a basic understanding of statistics) whilst introducing students to the central nervous system, its basic anatomy and development and stem cells. In parallel students would cover an introduction to neurodegenerative diseases (that would include Alzheimer’s Disease, Parkinson’s Disease and Motor Neurone Disease) before being introduced to in vitro and in vivo modelling of these diseases. Finally students would also learn about neuroimaging and its potential roles for scientific research.

Postgraduate Diploma

Expands on the PGCert courses as well as introducing greater depth to novel areas such as the roles of pharma and industry with respect to stem cells. A proportion of the Diploma credits are elective and students will be assisted in choosing appropriate options from across the broad spectrum available from Edinburgh University that are relevant to their own situation, employment and career goals.

MSc

Students have the opportunity to explore a specialist area from within the broad spectrum of stem cells, regeneration and translational neuroscience in the form of either a dissertation, or, a structured project (the student would themselves have to source this if desired), which would aim to deliver a ‘real world’ project with a direct impact for an employer, organisation or personal goal. A third option available for students is a choice of 60 fully taught credits.

The minimum recommended time for completion of the full Masters programme is three years, and the maximum time for completion is six years. The Certificate and Diploma can be completed on a pro rata basis.

Postgraduate Professional Development (PPD)

Postgraduate Professional Development (PPD) is aimed at working professionals who want to advance their knowledge through a postgraduate-level course(s), without the time or financial commitment of a full Masters, Postgraduate Diploma or Postgraduate Certificate.

You may take a maximum of 50 credits worth of courses over two years through our PPD scheme. These lead to a University of Edinburgh postgraduate award of academic credit. Alternatively, after one year of taking courses you can choose to transfer your credits and continue on to studying towards a higher award on a Masters, Postgraduate Diploma or Postgraduate Certificate programme.

Although PPD courses have various start dates throughout a year you may only start a Masters, Postgraduate Diploma or Postgraduate Certificate programme in the month of September. Any time spent studying PPD will be deducted from the amount of time you will have left to complete a Masters, Postgraduate Diploma or Postgraduate Certificate programme.

Career opportunities

Potential career paths, exits routes and employers are very diverse and depend on the students chosen carer. For students working in a clinical environment this programme would offer them career advancement/specialism within their clinical setting.

For students coming from a scientific background there is the opportunity to improve carer prospects in laboratory research settings or alternatively to help in progressing to a PhD.



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Course Description. The MRes offers exciting opportunities to develop advanced scientific, research and transferable skills required to become an independent researcher. Read more

Course Description

The MRes offers exciting opportunities to develop advanced scientific, research and transferable skills required to become an independent researcher.

The MRes is organised by the Centre for Human Development, Stem Cells & Regeneration (CHDSCR) which undertakes fundamental research into early development and stem cells, together with applied translational research targeting the NHS and patient benefit.

Through research projects totalling 32 weeks, you will develop a broad range of laboratory skills and work in different research environments. You will be supervised by internationally recognised academic researchers. In addition to providing broader training in scientific research, the course will develop your transferable skills including time and project management, public speaking, critical appraisal and scientific writing, thus aiding employability for a variety of careers.

Key Information

The intake for this MRes is 15-20 students.

What does this MRes provide?

During the one year, full time programme that commences in September/October, MRes students undertake taught modules in Research Skills in Biomedical Sciences, Stem Cells, Development & Regenerative Medicine, and Advanced Scientific Skills. Students also undertake two research projects totalling 32 weeks, to develop a broad range of laboratory skills and gain experience of working in different research environments. Students are supervised by internationally recognised Academic researchers in the CHDSCR.

Why study this MRes at the University of Southampton?

The University of Southampton is consistently ranked in the top 10 national and the top 100 international Universities. We are a world leading research intensive university, with a strong emphasis on education and are renowned for our innovation and enterprise. The CHDSCR is a Centre for excellence and strategic importance. Students work within vibrant and thriving interdisciplinary research programmes that harness the translational strength of the University, together with an outstanding clinical infrastructure and enterprise to translate pioneering developmental and stem cell science for patient benefit.

Who should apply?

High-achieving Biological/Biomedical Science graduates interested in developing further laboratory based research skills and subject specific knowledge before committing to a PhD programme, or a career in academia, industry, government policy or science journalism.

How will this MRes enhance your career prospects?

In addition to providing broader training in the intellectual basis of scientific research in Stem Cells, Development and Regenerative Medicine, the course will develop your transferable skills including time and project management, public speaking, critical appraisal and scientific writing, thus aiding employability for a variety of careers.

What will you learn in the modules?

i) Stem Cells, Development & Regenerative Medicine module

Students are introduced to core concepts through a series of facilitator-led workshops focussing on key research publications. Students critically appraise primary research papers and develop the skills required to understand, critique and interpret research findings. Integral to these workshops is the requirement for students to present their thoughts and participate in group discussions with both their peers and academic facilitators.

ii) Research Skills in Biomedical Sciences (RSBS) module

A combination of taught and practical sessions are used to introduce students to the core concepts underlying statistical analysis and study design that support students in handling their own data and critically appraising data published by others.

iii) Advanced Scientific Skills module

A series of taught and practical sessions introduce students to additional core concepts used in Biomedical Sciences such as the analysis and critical appraisal of large data sets. In addition, key principles required to relay research to both a scientific and lay audience are introduced. Students write both a scientific and lay abstract for a published primary paper and give a research presentation suitable for a lay audience. Thus, students develop the skills required to communicate their research to both scientists and non-specialists.

iv) Research Project modules

In the two research projects, students are introduced to a range of laboratory skills gaining valuable practical experience of research methodology, experimental design, data interpretation, viva voce, scientific writing, oral and poster presentations.

What teaching and learning methods will be used?

A variety of methods are used including lectures, research seminars, small group discussions, journal club presentations, analysis of large data sets and in depth research projects which incorporate the evaluation and presentation of research findings within the field of stem cell biology. A range of summative and formative assessment methods are used to assess student performance. These include oral presentation, poster presentation, written assignments/critical review, viva voce, laboratory proficiency, analysis of large datasets, lay/scientific abstracts and preparation of a research proposal.

What are the entry requirements for this MRes?

The minimum classification normally expected for a degree entrant is at least a second class upper division (1st or 2:1) in Biological/Biomedical Sciences or a closely related subject from any approved University.

Qualifications from non-UK institutions must be of an equivalent standard to those of UK Universities. Before commencing the course, non-UK applicants should obtain an overall IELTS score of 7.0, with a minimum of 6.0 in each component.

What are the fees for this MRes?

Home/EU: £5,900 tuition fee + £5,100 bench fee

Overseas: £18,800 tuition fee + £5,100 bench fee

Scholarships

The University of Southampton offers a number of Scholarships. Please refer to: http://www.southampton.ac.uk/uni-life/fees-funding/international-fees-funding/funding-by-country.page

To Apply

Please click on the “Apply Now” button on our website

Please state Faculty of Medicine in the drop down menu as this Programme is delivered by the Faculty of Medicine. Or click on the link below

https://studentrecords.soton.ac.uk/BNNRPROD/bzsksrch.P_Search

To register interest, or for further Programme information please contact:

Programme Leader: Dr Franchesca Houghton

Deputy Programme Leader: Dr Rahul Tare

Email:

For general enquiries please contact:

Email:



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The Master's in Cancer, Stem Cells and Developmental Biology guides you in exploring the mysteries of embryonic growth, stem cells, evolution and development in relation to health and disease. Read more

Cancer, Stem Cells and Developmental Biology

The Master's in Cancer, Stem Cells and Developmental Biology guides you in exploring the mysteries of embryonic growth, stem cells, evolution and development in relation to health and disease.

This Master's programme combines research in the fields of oncology,molecular developmental biology and genetics in animals and humans. During the major (9 months) and minor (6 months) research projects on topics of your own choice, you learn sophisticated modern techniques of genomics, proteomics and bioinformatics. It is possible to complete the minor research project in a laboratory of your choice abroad. During the two year research programme, you are required to take 10 weeks of theoretical courses in the areas grouped in five broad subject areas. You may choose your favourite courses from the list of courses organized by our programme, as well as by other programmes and institutes. Moreover, you are required to attend seminars that present research covering the full range of topics related to biomedical and life sciences.

A final Master's thesis, based on literature research on a relevant topic, completes your programme. It should present a clear overview of recent literature on the topic of interest and demonstrate your ability to critically evaluate hypotheses and results, present your own views and draw conclusions that may lead to the formulation of new research goals.

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This innovative distance-learning programme is taught online and will provide you with knowledge and understanding in the highly topical and exciting field of stem cell biology and regeneration. Read more
This innovative distance-learning programme is taught online and will provide you with knowledge and understanding in the highly topical and exciting field of stem cell biology and regeneration. You will be guided from the origins of this field through to its application (and potential applications) in treating human disease, covering the latest tools and technologies available for study in this area. Programme content is delivered by researchers active in the field, ensuring that the latest breakthroughs are communicated.

Using a creative distance-learning model, the programme delivers lectures, online discussions and assessments over the internet. This offers you more flexibility than traditional campus-based courses as you can study in your own environment. You will only be required to visit Bristol for your formal examinations at the end of the academic year. This distance-learning model, together with a part-time study option, makes the programme particularly appealing to those students who wish to combine full-time employment with study.

Programme structure

Core units
-Introduction to Stem Cells and Regeneration
-Neurodegeneration and Ophthalmic Disorders
-Molecular Tools in Stem Cells and Regeneration
-Peripheral Neuropathy and Spine
-Cell Signalling
-Biomaterials and their Use in the Skeletal System
-Stem Cells in Cardiac Systems
-Research Project/Dissertation

Careers

The programme can open up a number of different career opportunities. It can be used as a pathway to further studies (eg PhD) which in turn could lead to a research or academic career in the field. It can also open up opportunities in private industry, for example:
-Biotechnology sector research/sales
-Stem cell business development
-Stem cell banking
-Stem cell patents
-Stem cell clinical translation
-Charity research development
-Pharmaceutical industry
-Stem cell regulatory bodies

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Our Stem Cells and Regenerative Medicine MRes is a research-based course with a taught component that is equivalent to an MSc. It provides a springboard into a career that involves a working knowledge of scientific research. Read more
Our Stem Cells and Regenerative Medicine MRes is a research-based course with a taught component that is equivalent to an MSc. It provides a springboard into a career that involves a working knowledge of scientific research.

The course is designed for graduates with a BSc in the life sciences or other science disciplines, and for intercalating and fully qualified MBBS or BDS students. It can be taken either as a stand-alone qualification or as an entry route onto a PhD or MD.

The taught component of the course includes subject-specific content in the area of stem cells and regenerative medicine. You have the flexibility to develop your own bespoke course by selecting additional, complementary modules. You will also participate in training in general research principles, and other professional and key skills.

The subject-based modules focus on interdisciplinary research that seeks to convert stem cell research and technologies into cost-effective, ethically robust 21st century health solutions that will ameliorate degenerative diseases, the effects of ageing and serious injury. This strand is delivered jointly with Durham University, with project opportunities in both universities.

Your research project comprises the major element of the course. This project will involve 24 weeks of research in an area of stem cells and regenerative medicine under the supervision of an expert academic researcher in the field.

The course allows you to experience an internationally competitive research area, predominantly in academia but also potentially in industry.

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Academic, practical and research teaching covering all aspects of the latest developments in regenerative dentistry including dental stem cell culture, iPS and ES cells, tooth bioengineering, the role of stem cells in tooth repair and regeneration. Read more

Academic, practical and research teaching covering all aspects of the latest developments in regenerative dentistry including dental stem cell culture, iPS and ES cells, tooth bioengineering, the role of stem cells in tooth repair and regeneration. A major feature of the course is a research project carried out in one of our research labs and supported by practical demonstrations and evaluation of research publication.

Key benefits

  • Training in research methodologies and the critical evaluation of data.
  • Taught course on the very latest advances of stem cell research.
  • World renowned department.
  • Original research project.

Description

Taught course elements include: Introduction to stem cells, ES and iPS, Dental stem cells, Endogenous dentine repair, Endodontic applications of stem cells, Whole tooth regeneration, Scaffolds and bone regeneration, Salivary gland regeneration, Periodontal ligament restoration, GMP cell culture.

Research and practical elements include a research project, practical demonstrations of dental pulp stem cell culture combined with critical evaluation of research methods and approaches in dental stem cell biology.

Examples of research projects:

  • Salivary gland stem cells
  • Stem cells in the middle ear and their role in homeostasis and repair
  • Development of replacement teeth: location of stem cell niches in a range of species
  • A chemical genetics screen for regulators of cranial muscle stem cells
  • Dental pulp stem cells in tooth repair
  • Exploring the relationship between surface free energy and osseointegration with modifiable ceramic coatings
  • Human Embryonic tooth mesenchymal cells and bio-tooth engineering
  • Periodontal tissue regeneration - evaluating different human dental stem cell populations
  • Neural crest stem cells and ossification of the mandible

Course purpose

Regenerative dentistry is for both dentists and biological scientists who desire to learn more about the latest advances in cell and molecule-based dentistry and also gain experience in carrying out laboratory-based, cutting-edge research in dental stem cell biology.

Course format and assessment

Written exam, practical tests and written reports, seminar presentation.



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The utilisation of stem cells in the clinical arena is one of the most exciting areas of medicine today. Our MSc is designed to enable you to develop an up-to-date, advanced understanding of this exciting area of medicine and clinical research. Read more
The utilisation of stem cells in the clinical arena is one of the most exciting areas of medicine today. Our MSc is designed to enable you to develop an up-to-date, advanced understanding of this exciting area of medicine and clinical research. Regenerative medicine has the potential to impact on conditions as varied as spinal injury, coronary heart disease and type 1 diabetes.

Why Study Stem Cells and Regenerative Medicine with us?

You will receive training in the skills required in the reading and interpretation of the literature and translating that into evidencebased practice. We will develop your research and writing skills so that you will be in a position to contribute to the scientific literature in an effective manner.

The course culminates in the Research Dissertation, which will be assessed through your production of two publishable scientific articles.

If biomedical or clinical research is your interest, successful completion of the MSc will allow you to directly register onto PhD study and join our team of researchers at the Institute of Medicine.

What will I learn?

Our course is designed to provide an in-depth, current look at stem cell technology and its application in medicine. We look at stem cell theory and then apply this to clinical problems. You will develop critical analytical skills so that you will be able to evaluate new developments in research into regenerative medicine. You will also carry out a research project in one of these areas.

Seminars and tutorials will be held with various healthcare professionals and clinical researchers.

How will I be taught?

Our course consists of taught modules and a Research Dissertation.

We deliver taught modules as three-day intensive courses to facilitate attendance from students in employment. Weekly support sessions and journal club supplement learning – all held in our modern facilities in Bache Hall.

How will I be assessed?

You will be assessed via clinical reviews, laboratory reports, posters, oral presentations, or data manipulation exercises.

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This programme aims to provide a high level of scientific knowledge and understanding of stem cell biology and regenerative medicine - from the molecular to the whole system level. Read more
This programme aims to provide a high level of scientific knowledge and understanding of stem cell biology and regenerative medicine - from the molecular to the whole system level.

Course Outline & Modules

This programme aims to provide a high level of scientific knowledge and understanding of stem cell biology and regenerative medicine - from the molecular to the whole system level. The programme aims to enable students to develop an informed and critical appreciation of recent scientific developments in these areas of modern biomedical sciences and its clinical and industrial application, as well as a practical skill set for further research and learning, e.g. PhD studies.

The opportunity to undertake a work experience placement will enable students to further their employability and transferable skills and develop links with participating clinical and industrial partners.

This course offers a flexible framework of core and optional modules. The core modules are:
-Advanced Laboratory Skills with data analysis and interpretation
-Understanding Professional Practice & Enhancing your Employability
-Mammalian Cell Biology and Culture
-Stem Cells and Tissue Engineering Technology
-Tissue Formation, Function and Repair
-Models of Regeneration I

Optional modules include, but are not limited to:
-Ageing and Regenerative Medicine
-Transplantation Biology
-Finance and Business Management

Note that not all options may be available in any one year and that options will not proceed if the minimum student intake number is not reached.

Learning, Teaching & Assessment

The programme is delivered using a combination of lectures, practical classes, tutorials and seminars. Some modules will include group work. The core employability module will use visiting lecturers from industry to illustrate the potential employment avenues for graduates of this course. The course includes a research project, this is likely to be a laboratory-based project where students will collect and analyse their own data. Assessment methods employed include examinations and continuous assessment through coursework; these will differ for individual modules.

Career Opportunities

Completion of this course prepares students for a research-focussed role in industry, including the developing clinical field of stem cell therapies of regenerative medicine, or academia. Graduates can therefore expect to enter further research, in the form of a PhD or research assistant, or may undertake a career in the commercial or clinical sector.

Personal Development

Completion of this course prepares students for a research-focussed role in industry, including the developing clinical field of stem cell therapies of regenerative medicine, or academia. Graduates can therefore expect to enter further research, in the form of a PhD or research assistant, or may undertake a career in the commercial or clinical sector.

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The course is a unique combination of. in advanced therapeutic medicines and will provide academic and laboratory research training in three key areas (streams). Read more
The course is a unique combination of

'hot' and rapidly developing topics

in advanced therapeutic medicines and will provide academic and laboratory research training in three key areas (streams):

•Gene and Nucleic Acid Based Therapies
•Regenerative Medicine
•New Horizons in Pharmacology

The main purpose of this programme is to facilitate state-of-the-art education in next generation therapies for scientist and clinicians, who will be equipped to significantly contribute to these rapidly expanding fields.

A major focus is training in

translational research

illustrating all steps required to progress novel therapies from bench-to-bedside and towards drug licensing.

It is the provision of teaching in all three areas of advanced therapeutic development which makes our programme unique.

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The minimum entry criteria for the PgCert/PgDip Stem Cell Biology are as follows. Read more

Entry Requirements

The minimum entry criteria for the PgCert/PgDip Stem Cell Biology are as follows:

(a) Applicants must hold a degree in a relevant life science discipline or another related discipline from a University in the United Kingdom or the Republic of Ireland, or from an institution which is recognised by the Senate for this purpose; or

(b) Candidates who do not meet the above requirements but who hold other qualifications and professional experience may be considered eligible for admission to the programme by accreditation of prior experiential learning (APEL). Those candidates who wish to be considered in terms of experiential learning must complete an APEL form and send this with their application.

(c) Candidates will have to provide evidence of adequate English language skills. Overseas applicants may demonstrate competence through either a TOEFL score of 550 (or computer based), or an IELTS score 6.0.

Course Description

The cutting edge PgCert course will provide you with knowledge and skills required to pursue a career in the rapidly expanding field of stem cell biology. The PgDip will further develop your skills in experimental design and stem cell commercialization. Successful completion of the course will allow you to capitalise on opportunities in areas such as research, law, clinics and industry. You will study in a supportive and collaborative online environment where you will be supported by an e-tutor. The course will cover the latest exciting advances in stem cell science and equip you with the skills to critically analyse these discoveries not only during the course but during your future career.

Visit: http://www.ulster.ac.uk/course/pgcert-stem-cell-biology-pt-e

Structure and Content

The PgCert course consists of two modules (60 credit points). The first module in Stem Cell Biology will equip you with up to date knowledge on various topics such as sources of stem cells e.g. adult, embryonic and induced pluripotent stem cells, pluripotency, current and future uses of stem cells and bioethics. This module also introduces you to the skills which will enable you to evaluate future advances in stem cell research following the end of the course. The second module in Evidence Based Healthcare Practice will allow you to evaluate how stem cells are currently used and inform future practice in this area.
The PgDip course consists of a further 3 modules in Techniques in Stem Cell Biology, Commercialization of Stem Cells and Research Skills & Statistics (5 modules worth 120 credit points in total). These modules will equip you with the knowledge to design experiments involving stem cells and lead you through the commercialization process, topics which our Industrial Advisory Board recommend are highly sought after skills in stem cell industry employees.

Teaching Methods and Assessment

The course is delivered as a series of online lectures designed by a range of experts and multimedia resources in the various areas of stem cell biology. The flexible nature of the course allows you to study at your own pace. You can study 1 or two modules each semester. The course will be supplemented by online discussions with e-tutors, access to specialist online talks and interactive quizzes.

Assessment will be by 100% coursework which will take various forms including contributions to online discussions, online quizzes and various pieces of written work.

Why Choose Ulster University ?

1. Over 92% of our graduates are in work or further study six months after graduation.
2. We are a top UK university for providing courses with a period of work placement.
3. Our teaching and the learning experience we deliver are rated at the highest level by the Quality Assurance Agency.
4. We recruit international students from more than 100 different countries.
5. More than 4,000 students from over 50 countries have successfully completed eLearning courses at Ulster University.

Flexible payment

To help spread the cost of your studies, tuition fees can be paid back in monthly instalments while you learn. If you study for a one-year, full-time master’s, you can pay your fees up-front, in one lump sum, or in either five* or ten* equal monthly payments. If you study for a master’s on a part-time basis (e.g. over three years), you can pay each year’s fees up-front or in five or ten equal monthly payments each year. This flexibility allows you to spread the payment of your fees over each academic year. Find out more by visiting https://www.ulster.ac.uk/apply/fees-and-finance/postgraduate

Scholarships

A comprehensive range of financial scholarships, awards and prizes are available to undergraduate, postgraduate and research students. Scholarships recognise the many ways in which our students are outstanding in their subject. Individuals may be able to apply directly or may automatically be nominated for awards. Visit the website: https://www.ulster.ac.uk/apply/fees-and-finance/scholarships

English Language Tuition

CELT offers courses and consultations in English language and study skills to Ulster University students of all subjects, levels and nationalities. Students and researchers for whom English is an additional language can access free CELT support throughout the academic year: https://www.ulster.ac.uk/international/english-language-support

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This pioneering course aims to maximise the employability of students. Our track record shows 90% of graduates secure ste cell technology-related posts including PhDs, positions in industry and government-funded agencies (e.g. Read more

Overview

This pioneering course aims to maximise the employability of students. Our track record shows 90% of graduates secure ste cell technology-related posts including PhDs, positions in industry and government-funded agencies (e.g. stem cell banks).

The course content has been designed in consultation with stem cell experts and potential employers in biotechnology, academia, industry and bodies regulating stem cells, to provide the necessary expertise to compete in an ever changing world.

Highlights

- Students learn a broad range of transferable skills including critical analysis, data handling, and oral and written skills.
- Teaching is by leading research scientists who are working at the cutting edge of new developments, ensuring the most recent research is integrated into the course.
- Teaching also incorporates guest speakers recognised as international experts in the stem cell technology field, including clinicians who want to use stem cells in regenerative medicine.

Modules

The course incorporates the following modules:

- Cell, Developmental and Molecular Biology
- Module 2: Embryonic Stem Cells
- Module 3: Adult and Fetal Stem Cells
- Module 4: Translational Technologies for Stem Cells
- Module 5: Research Skills & Stem Cell Technology Exploitation
- Module 6: Regenerative Medicine Research Project

Approximately 40% of the taught modules encompass direct laboratory training. This high level of practical work means we take a maximum of 16 students. This ensures we have good tutor/student ratios and specialist equipment is widely accessible.

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The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Read more
The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Research areas include: genetic medicine, developmental genetics, neuromuscular and neurological genetics, mitochondrial genetics and cardiovascular genetics.

As a research postgraduate in the Institute of Genetic Medicine you will be a member of our thriving research community. The Institute is located in Newcastle’s Life Science Centre. You will work alongside a number of research, clinical and educational organisations, including the Northern Genetics Service.

We offer supervision for MPhil in the following research areas:

Cancer genetics and genome instability

Our research includes:
-A major clinical trial for chemoprevention of colon cancer
-Genetic analyses of neuroblastoma susceptibility
-Research into Wilms Tumour (a childhood kidney cancer)
-Studies on cell cycle regulation and genome instability

Cardiovascular genetics and development

We use techniques of high-throughput genetic analyses to identify mechanisms where genetic variability between individuals contributes to the risk of developing cardiovascular disease. We also use mouse, zebrafish and stem cell models to understand the ways in which particular gene families' genetic and environmental factors are involved in the normal and abnormal development of the heart and blood vessels.

Complex disease and quantitative genetics

We work on large-scale studies into the genetic basis of common diseases with complex genetic causes, for example autoimmune disease, complex cardiovascular traits and renal disorders. We are also developing novel statistical methods and tools for analysing this genetic data.

Developmental genetics

We study genes known (or suspected to be) involved in malformations found in newborn babies. These include genes involved in normal and abnormal development of the face, brain, heart, muscle and kidney system. Our research includes the use of knockout mice and zebrafish as laboratory models.

Gene expression and regulation in normal development and disease

We research how gene expression is controlled during development and misregulated in diseases, including the roles of transcription factors, RNA binding proteins and the signalling pathways that control these. We conduct studies of early human brain development, including gene expression analysis, primary cell culture models, and 3D visualisation and modelling.

Genetics of neurological disorders

Our research includes:
-The identification of genes that in isolation can cause neurological disorders
-Molecular mechanisms and treatment of neurometabolic disease
-Complex genetics of common neurological disorders including Parkinson's disease and Alzheimer's disease
-The genetics of epilepsy

Kidney genetics and development

Kidney research focuses on:
-Atypical haemolytic uraemic syndrome (aHUS)
-Vesicoureteric reflux (VUR)
-Cystic renal disease
-Nephrolithiasis to study renal genetics

The discovery that aHUS is a disease of complement dysregulation has led to a specific interest in complement genetics.

Mitochondrial disease

Our research includes:
-Investigation of the role of mitochondria in human disease
-Nuclear-mitochondrial interactions in disease
-The inheritance of mitochondrial DNA heteroplasmy
-Mitochondrial function in stem cells

Neuromuscular genetics

The Neuromuscular Research Group has a series of basic research programmes looking at the function of novel muscle proteins and their roles in pathogenesis. Recently developed translational research programmes are seeking therapeutic targets for various muscle diseases.

Stem cell biology

We research human embryonic stem (ES) cells, germline stem cells and somatic stem cells. ES cell research is aimed at understanding stem cell pluripotency, self-renewal, survival and epigenetic control of differentiation and development. This includes the functional analysis of genes involved in germline stem cell proliferation and differentiation. Somatic stem cell projects include programmes on umbilical cord blood stem cells, haematopoietic progenitors, and limbal stem cells.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.

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Within the Developmental Biology research area a number of model systems are being used to study various aspects of vertebrate development with a major focus being on the development of stem cells. Read more
Within the Developmental Biology research area a number of model systems are being used to study various aspects of vertebrate development with a major focus being on the development of stem cells. Specific projects include: the development of blood stem cells and vasculature in zebrafish; the development of neural stem cells in zebrafish and in mice; the properties of mesenchymal stem cells; primordial germ cells and gene networks that govern the development of vertebrate embryos.

APPLICATION PROCEDURES

After identifying which Masters you wish to pursue please complete an on-line application form
http://www.nottingham.ac.uk/pgstudy/apply/apply-online.aspx

Mark clearly on this form your choice of course title, give a brief outline of your proposed research and follow the automated prompts to provide documentation. Once the School has your application and accompanying documents (eg referees reports, transcripts/certificates) your application will be matched to an appropriate academic supervisor and considered for an offer of admission.

COURSE STRUCTURE
The MRes degree course consists of two elements:
160 credits of assessed work. The assessed work will normally be based entirely on a research project and will be the equivalent of around 10 ½ months full-time research work. AND
20 credits of non-assessed generic training. Credits can be accumulated from any of the courses offered by the Graduate School. http://www.nottingham.ac.uk/gradschool/research-training/index.phtml The generic courses should be chosen by the student in consultation with the supervisor(s).

ASSESSMENT
The research project will normally be assessed by a dissertation of a maximum of 30,000 to 35,000 words, or equivalent as appropriate*. The examiners may if they so wish require the student to attend a viva.
*In consultation with the supervisor it maybe possible for students to elect to do a shorter research project and take a maximum of 40 credits of assessed modules.

The School of Life Sciences will provide each postgraduate research student with a laptop for their exclusive use for the duration of their studies in the School.

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The Transplantation MRes enables you to experience an internationally competitive research area, predominantly in academia but also potentially in industry. Read more

The Transplantation MRes enables you to experience an internationally competitive research area, predominantly in academia but also potentially in industry. The MRes can be taken either as a stand-alone qualification or provide an entry route onto a PhD or MD.

The course is designed for graduates with a BSc in the life sciences and is also suitable for graduates from other science disciplines and intercalating and fully qualified MBBS or BDS students.

What you'll learn

There is a taught component with subject-specific content in the area of Transplantation. Subject-based modules provide a broad exposure to diverse aspects of transplantation, from clinical concepts to cutting edge scientific development. There will be a unique opportunity to gain insights into the speciality of transplantation sciences in the context of transplantation of haematopoietic stem cells, corneal/limbal stem cells and a variety of solid organs.

The modules aim to:

  • provide sound understanding of the scientific basis underlying the therapeutic benefits and adverse effects of clinical transplants
  • highlight the research areas where applications of immunology and cell biology can improve transplant outcome and patient wellbeing
  • provide a view of bench to bedside translational links between scientific research and clinical practice

The course emphasises the clinical practice driven research, which prepares students for a future career in either medical practice or broad biomedical research. 

Main topics covered include:

  • transplantation immunology related to cellular and molecular basis of allogeneic immune responses, tolerance, immunosuppression
  • the genetic and molecular basis of HLA system, non-HLA immunogenetics, histocompatibility, impact of HLA matching in choice of donor and transplant outcome
  • transplantation pathology related to graft-versus-host disease following haematopoietic stem cell transplant, rejection following solid organ transplant, tissue damage and loss of graft function
  • manipulation of haematopoietic stem cells for clinical use
  • development of novel therapeutic strategies to aid improvement of clinical transplant outcome

It has the flexibility for you to develop your own bespoke course by choosing additional, complementary modules from a wide selection. You will also undertake training in general research principles and other professional and key skills.

Your project

The research project comprises the major element of the course. This project will involve 24 weeks’ carrying out research in the area of transplantation under the supervision of an expert academic researcher in the field.

Our MRes courses

Transplantation MRes is closely linked to a suite of MRes courses that you may also be interested in:

Faculty of Medical Sciences Graduate School

Our Medical Sciences Graduate School is dedicated to providing you with information, support and advice throughout your research degree studies. We can help and advise you on a variety of queries relating to your studies, funding or welfare.

Our Research Student Development Programme supports and complements your research whilst developing your professional skills and confidence.

You will make an on-going assessment of your own development and training needs through personal development planning (PDP) in the ePortfolio system. Our organised external events and development programme have been mapped against the Vitae Researcher Development Framework to help you identify how best to meet your training and development needs.



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The pharmaceutical and life sciences industries are investing in stem cells, either in direct applications where the stem cells themselves would be used for therapy or indirectly, where stem cell derived tissues will be used for drug screening and toxicity testing. Read more

The pharmaceutical and life sciences industries are investing in stem cells, either in direct applications where the stem cells themselves would be used for therapy or indirectly, where stem cell derived tissues will be used for drug screening and toxicity testing.

This programme is intended to meet current and future needs of the pharmaceutical industry and health care providers by providing a cadre of well-trained scientists capable of fulfilling managerial, administrative, research and technical roles within the developing commercial regenerative medicine sector.

Our programme covers key theoretical and practical aspects of the growth and maintenance of pluripotent stem cell lines, the directed differentiation of these cells into defined tissue phenotypes, and the maintenance of the differentiated state under conditions suitable for drug testing/screening programs.

Essential elements of good practice will also be included, such as quality assurance and the regulatory framework that surrounds the derivation, storage and use of human cells.

Our teaching is multidisciplinary, with contributions from the fields of medicine, biology, chemistry and bioinformatics.

Programme structure

The programme contains both taught and independent project components.

Compulsory courses

  • Fundamental Biology of Stem Cells
  • Basic Techniques in Regenerative Medicine
  • Stem Cells and Regenerative Medicine
  • Production of Differentiated Cells
  • Regenerative Medicine and the Clinic or Regenerative Medicine and Industry

Industrial placement

There will be an industrial placement of three months, situated within a life sciences company specialising in aspects of regenerative medicine. Financial assistance may be available to cover travel expenses to the location of the industrial placement.

Career opportunities

Graduates will be equipped for a variety of roles within the developing commercial regenerative medicine sector.



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