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A Masters’ studentship is available in the group of Dr. Martin Schröder in the School of Biological and Biomedical Sciences at Durham University to study stress signaling mechanisms originating from the endoplasmic reticulum. Read more
A Masters’ studentship is available in the group of Dr. Martin Schröder in the School of Biological and Biomedical Sciences at Durham University to study stress signaling mechanisms originating from the endoplasmic reticulum. Endoplasmic reticulum (ER) stress contributes to the development and progression of many diverse diseases affecting secretory tissues, such as diabetes and neurodegenerative diseases. The successful candidate will employ modern genetic and molecular techniques to understand the underlying cell biological mechanisms in endoplasmic reticulum stress signaling that maintain the homeostasis of the endoplasmic reticulum.

The MRes student will investigate control of ER stress signaling specificity by the dosage of ER stress. You will use a range of molecular biology and biochemical techniques to study (a) how the severity of ER stress alters the signaling outputs of the ER stress sensing protein kinase-endoribonuclease IRE1 or (b) how ER stress regulates transcriptional responses through the Rpd3-Sin3 histone/lysine deacetylase (see for example Schröder et al., 2000; Schröder et al., 2004). These techniques include protein expression and purification, immunoprecipitation, chromatin immunoprecipitation, cloning, transfection, and RNA analysis by real-time PCR or Northern blotting.

Overall, the studentship will provide interdisciplinary training in molecular biology, genetics, and cell biology.

References

M. Schröder, Cell. Mol. Life Sci. 65 (2008) 862-894: Endoplasmic reticulum stress responses.
M. Schröder, C. Y. Liu, R. Clark, and R. J. Kaufman, EMBO J. 23 (2004) 2281-2292: The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase.
M. Schröder, J. S. Chang, and R. J. Kaufman, Genes Dev. 14 (2000) 2962-2975: The unfolded protein response represses nitrogen-starvation induced developmental differentiation in yeast.

To apply

To apply: send a CV including the names of two references and a one page personal statement describing clearly your background, interest and experience in scientific research to . In your cover letter you should clearly identify the funding source to cover living expenses, tuition fees and bench fees. Further information can be found at https://www.dur.ac.uk/martin.schroeder or by contacting Dr. Martin Schroeder.

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The Graduate Program in Pharmaceutical Sciences, located on the Texas Tech University Health Sciences Center (TTUHSC) campus at Amarillo, Texas offers Masters (M.S.) and Doctoral (Ph.D.) degrees in integrated biomedical/pharmaceutical research as part of the TTUHSC Graduate School of Biomedical Sciences. Read more
The Graduate Program in Pharmaceutical Sciences, located on the Texas Tech University Health Sciences Center (TTUHSC) campus at Amarillo, Texas offers Masters (M.S.) and Doctoral (Ph.D.) degrees in integrated biomedical/pharmaceutical research as part of the TTUHSC Graduate School of Biomedical Sciences.

About the Program

Modern pharmaceutical science encompasses a number of disciplines, including biochemistry, molecular biology, physiology, immunology, pharmacology, pharmaceutics, and medicinal chemistry. The field is unified by the search for novel drug targets and the development of new agents and formulations for the treatment biomedical disease. This includes cutting edge techniques to target drugs to sites of therapeutic action and to reduce adverse effects related to drug metabolism, lack of target selectivity, and pharmacogenetic differences within the human population. PhD’s in pharmaceutical science are well trained for drug discovery and development positions in academic labs, government (e.g., Food and Drug Administration), and the pharmaceutical or biotech industries.
Each student completes a core curriculum including foundation training in biochemistry, physiology, pharmacology and pharmaceutics designed to give students a basic understanding of the biomedical processes by which the body operates and the pharmaceutical agents and delivery systems available to interact with these systems. Electives studies offer the student the opportunity for specialization in more focused areas of interest, including receptor biology, molecular drug action, cell signaling, cancer research, pharmacokinetics, drug metabolism, and biotechnology. Communication, research design, professional skills and ethics are developed throughout the curriculum in complementary courses. Students become immersed in the philosophy of life-long learning and the importance of maintaining and updating their knowledge base as critical, independent thinkers and scientists. The faculty sees this integrated approach as one of the primary strengths of the program, combining cutting-edge molecular and biomedical breakthroughs with modern drug development, targeting and formulation. A broad range of biomedical and pharmaceutical research opportunities are available throughout the department. Focus areas of the Department with links to specific faculty interests are listed below:
Aging/Brain/Neuroprotection/Stroke
Blood Brain Barrier and Neurovascular
Cancer and Molecular Biology & Therapy
Cardiovascular Disease & Regulation
Drug Discovery and Formulation & Pharmacokinetics
Receptor Biology, Cell Signaling & Immunotherapy

Funding

Typically, students may complete a course of study for a Ph.D. degree within 4-5 years or a Masters degree in about half that time (2-2.5 years). Funding is available in the form of stipends ($23,000) from the Department/Graduate School and from individual faculty research resources. These stipends are awarded on a competitive basis to qualifying Ph.D. candidates. Currently, the Department has 43 funded graduate students.

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The William Harvey Research Institute is currently the UK’s largest academic pharmacological research institute and has a long history of training talented scientists for careers in translational research. Read more
The William Harvey Research Institute is currently the UK’s largest academic pharmacological research institute and has a long history of training talented scientists for careers in translational research.

During the year students will obtain a comprehensive training in in vivo techniques, key laboratory skills, research governance, the application of state-of-the-art imaging techniques and generic transferable skills followed by an opportunity to conduct an in-vivo based research project. The highest ranking students may be offered the opportunity to build upon their MRes studies and conduct a fully-funded 3 year PhD within the WHRI with their chosen supervisor.

All students will be based in the attractive Charterhouse Square campus in the City of London with access to exceptional scientific and recreational facilities.

This training will be an invaluable foundation for individuals wishing to pursue a career in industry or academic research, particularly in the areas of inflammation science, cardiovascular research or cell signaling.

http://www.qmul.ac.uk/postgraduate/coursefinder/courses/121370.html

For further information, please contact:

Dr Nina Ravic


or

Prof Amrita Ahluwalia



To apply
https://mysis.qmul.ac.uk/urd/sits.urd/run/siw_ipp_lgn.login?process=siw_ipp_app&code1=PFQM-A3R2-09&code2=0004&code3=GUEST

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The programme includes the following profiles. This profile introduces students into the study of animal and plant development, microbiology, cell signaling pathways, cytoskeleton dynamics, cancer biology, virology and immunology. Read more
The programme includes the following profiles:

Genetics, Cell and Developmental Biology

This profile introduces students into the study of animal and plant development, microbiology, cell signaling pathways, cytoskeleton dynamics, cancer biology, virology and immunology. Courses of this profile span multiple levels of biological organization, from whole organisms down to the molecular level. Students choosing this profile not only receive up-to-date knowledge on these topics but also acquire the laboratory skills required to engage in cutting-edge research.

Environment, Biodiversity and Ecosystems

This profile allows students to gain experience in the research methods used to study the evolution and ecology of organisms found in terrestrial, freshwater and coastal ecosystems. A staff of experts teaches up-to-date knowledge on individual organisms, populations, species communities and ecosystems, backed up by their active research experience in taxonomy and phylogeny, vertebrate and invertebrate ecology, evolutionary ecology, biogeography, plant ecology, plant-animal interactions, and nature management. In addition, students are introduced into ecological research by means of practical field training and excursions in Belgium and abroad.

Herpetology

This unique profile addresses biology students with a passion for amphibians and reptiles. An international team of visiting scientists organizes lectures on diversity, ecology, physiology, behavior, evolution and conservation biology and prepares students for a professional career in herpetology. Ecological and herpetological field courses in European and tropical countries form an important part of this programme. As a student, you will be in a stimulating environment, with fellow students and top-experts sharing your passion. For more information, have a look at http://www.herpetology.be.

Human Ecology

This profile focuses on the interaction between humans and their natural environment. The increasing impact of the human population on ecosystems worldwide stresses the urgent need for researchers with a multidisciplinary background, that engage in developmental plans for a durable use and management of natural resources. The profile Human Ecology addresses an international audience of students and offers a course programme that, besides scientific topics, also addresses technological, socio-economical and political aspects. For more information, have a look at http://www.humanecology.be.

EMMC Tropical Biodiversity and Ecosystems

The world faces a crisis risking extinction of species through global warming. Due to impact of e.g., changes in land use and destruction of habitats, tropical rain forests, mangrove forests and coral reefs are disappearing and with them ecosystem functions, goods and services on which human populations are dependent. In order to conserve nature, to manage or even to restore tropical biodiversity and ecosystems, we must understand patterns of tropical biodiversity, study how organisms interact with their environment and how they respond to perturbations and change. Next to research, this is dealt with in this unique masters programme. http://www.tropimundo.eu

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The Centre for Digestive and Gut Health at Imperial College London has developed this unique MRes stream course, which provides core training in microbiology, nutrition, hepatology and microbial signalling, as well as analytical technologies. Read more

Course Overview

The Centre for Digestive and Gut Health at Imperial College London has developed this unique MRes stream course, which provides core training in microbiology, nutrition, hepatology and microbial signalling, as well as analytical technologies. Students will learn about multidisciplinary approaches to systemic understanding of the gut microbiome and developing new targets for disease prevention and treatment.

This course exposes students to the latest developments in the field through two mini-research projects of 20 weeks' lab time, supplemented by lectures and journal clubs. The MRes course provides specific Gut Health teaching in microbiology, nutrition, microbial signaling and liver and gastrointestinal diseases, as well as analytical technology teaching aligned with the MRes in Biomedical Research. In addition to structured teaching, the MRes year consists of two 5-month laboratory research attachments.

Course Objectives

Students will gain experience in applying technologically advanced approaches to biomedical questions. Individuals who successfully complete the course will have developed the ability to:
• Perform novel laboratory based research and exercise critical scientific thought in the interpretation of results
• Undertake two research projects in line with the multidisciplinary culture of the Centre
• Demonstrate practical and intellectual dexterity in the research project elements
• Develop an appreciation of cutting edge technologies discovering host-microbial communication and current understanding of this association in human health and disease by attending the taught course elements
• Be able to interpret and present scientific data
• Be able to interrogate relevant scientific literature and develop research plans
• Be able to write a grant application, through the taught grant-writing exercise
• Be able to write and defend research reports through writing, poster presentations and seminars
• Exercise a range of transferable skills by taking a minimum number of short courses taught through the Graduate School

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For more information about the Centre for Digestive and Gut Health, please visit http://www1.imperial.ac.uk/centrefordigestiveandguthealth/

For more course information, please contact Dr. Jia Li (see the contact details above)

For online application, please visit https://apply.embark.com/grad/imperial/

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The MRes in Biochemistry and Cell Biology at University College Cork is a research-intensive course designed to maximize a student's hands-on laboratory experience and research skills. Read more

Key Features of the MRes in Biochemistry and Cell Biology

The MRes in Biochemistry and Cell Biology at University College Cork is a research-intensive course designed to maximize a student's hands-on laboratory experience and research skills. The 12-month research project is supervised by an internationally-recognized investigator based in the School of Biochemistry and Cell Biology. Research projects are available in the areas of bioanalysis, bioinformatics, proteomics, cancer biology, cell signaling, gene expression, trafficking, molecular genetics, neurobiology, RNA biology, translational control and synthetic biology. The MRes has a strong focus on presentation and writing skills that are required for a successful research career, including research planning proposal writing. In addition to this, students develop their general and transferable skills in laboratory techniques and safety, research ethics and integrity, information literary, science communication and statistics. Students are also required to attend weekly research seminars presented by both external and internal speakers.

Core and Elective Modules

Students in the MRes programme begin their research projects with a selected supervisor in week two, following a research induction and orientation. In addition to the research component, the following modules must be completed:
- Scientific Communication of Current Topics in Molecular Cell Biology
- Scientific Research Planning and Proposals
Students must also complete one (10-credit) or two (5-credit) electives from several options:
- Scientific Training for Enhanced Postgraduate Studies
- Biotechniques
- Information Literacy Skills
- Scientific Outreach and Communication
- Introduction to Research Ethics
- Statistics and Data Analysis for Postgraduate Research Students

Why choose the MRes in Biochemistry and Cell Biology?

With an emphasis on the individual, the MRes has a dedicated director and experienced academic staff who will help students fulfill their research career ambitions. The School of Biochemistry and Cell Biology is a strong research unit based at University College Cork, Ireland's first 5 star university (QS) and the world's first 'Green Campus'. Recently named 'University of the Year 2016' by The Sunday Times and located within walking distance of Cork city centre, UCC enjoys a great location and a vibrant campus.
Students who complete the MRes will be competitive to secure a PhD position or enter directly into employment within the biotechnology or pharmaceutical sectors. All of the students in our current class have ambitions of continuing on to a PhD.

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