This Masters in Bioinformatics (formerly Bioinformatics, Polyomics and Systems Biology) is an exciting and innovative programme that has recently been revamped. Bioinformatics is a discipline at the interface between biology, computing and statistics and is used in organismal biology, molecular biology and biomedicine. This programme focuses on using computers to glean new insights from DNA, RNA and protein sequence data and related data at the molecular level through data storage, mining, analysis and graphical presentation - all of which form a core part of modern biology.
Bioinformatics helps biologists gain new insights about genomes (genomics) and genes, about RNA expression products of genes (transcriptomics) and about proteins (proteomics); rapid advances have also been made in the study of cellular metabolites (metabolomics) and in a newer area, systems biology.
‘Polyomics’ is an intrinsically systems-level approach involving the integration of data from these ‘functional genomics’ areas - genomics, transcriptomics, proteomics and metabolomics - to derive new insights about how biological systems function.
The programme structure is designed to equip students with understanding and hands-on experience of both computing and biological research practices relating to bioinformatics and functional genomics, to show students how the computing approaches and biological questions they are being used to answer are connected, and to give students an insight into new approaches for integration of data and analysis across the 'omics' domains.
On this programme, you will develop a range of computing and programming skills, as well as skills in data handling, analysis (including statistics) and interpretation, and you will be brought up to date with recent advances in biological science that have been informed by bioinformatics approaches.
The programme has the following overall structure
Additional information about the programme can be found in the Bioinformatics MSc Programme Structure 2017-18.
Please note: students undertaking the three month PgCert will also be required to take two exams in March/April.
Most of our graduates embark on a University or Institute-based research career path, here in the UK or abroad, using the skills they've acquired on our programme. These skills are now of primary relevance in many areas of modern biology and biomedicine. Many are successful in getting a PhD studentship. Others are employed as a core bioinformatician (now a career path within academia in its own right) or as a research assistant in a research group in basic biological or medical science.
A postgraduate degree in bioinformatics is also valued by many employers in the life sciences sector - eg computing biology jobs in biotechnology, biosciences, neuroinformatics and the pharma industries.
Some of our graduates have entered science-related careers in scientific publishing or education. Others have gone into computing-related jobs in non-bioscience industry or the public sector.
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Instructions in English:
In the 2016-2017 academic year, the University of Padova inaugurated a new curriculum of the Master Degree “Biotechnology applied to Food Security and Nutrition” (Second Cycle Degree) entitled “Biotechnologies for Food Science " to be entirely taught in English.
The “Biotechnologies for Food Science " Master degree (MSc) is an interdisciplinary and research-oriented Master of Science Programme and explores how to produce healthier and safer food following a cross-cutting, farm/field-to-fork approach. It is focused on the application of advanced biotechnologies in food production and safety and it is the ideal trait-d’union between the requests of consumers, of producers in the agro-food sector and research applied to production and food-safety.
The course has a strong component on cutting-edge methods, such as genomics, bioinformatics, proteomics, metabolomics, nanotechnologies, all in the context of animal and crop production as well as food quality and safety. Theoretical lessons are mixed with practical training, offering hands-on experience in advanced DNA, RNA, and protein analysis together with substantial lab sessions in bioinformatics. Lectures will deal with food production, hygiene and quality, molecular methods of agro-food analyses, effects of agro-biotech products on human beings and environments. Moreover environmental stresses, disease mechanisms, pathogens and pests will be treated as essential to understand how to protect crop and farm animals and how food might impact on human health: the lectures move across animal infectious disease, immunology, microbiology, plant pests and pathogens as well as abiotic stresses to show how biotechnology might help preventing disease and improve food production. As consumers are increasingly worried about the presence of contaminants in food and on the real origin of what they eat; the Programme includes a course in food toxicology and regulation, and one on traceability for food authentication.
Our Programme is based at the Agripolis campus, where are located four departments of the School of Agriculture and Veterinary Medicine of the University of Padova, all of which contribute to the MSc course, offering the best opportunities for a rich, cross-disciplinary experience in a highly qualified scientific environment.
This programme is open to Italian and foreign students from the EU and abroad, interested in learning and implementing effective value-added practices for the production of high-quality food products both in the EU and in international markets. English knowledge must be minimum at B2 level (CEFR). Applying students might possibly have a three-year Bachelor’s degree in a field connected with the Master’s curriculum. Good background in molecular biology, biochemistry, and microbiology is requested.
Biotechnologies for Food Science is a 2-year Master programme (120 ECTS, equivalent to a Master of Science). Requirements for graduation include courses and preparation and defense of the Master thesis. Students will be encouraged to spend a period of their studies abroad, through Erasmus+ or other local programmes and agreements. Financial support to meet part of the cost for thesis work is granted to best students.
Visit the MSc “Biotechnologies for Food Science” page on the Università di Padova web-site (http://www.unipd.it/en/biotecnologie-alimentazione) for more details.
Teaching takes place in an international environment and includes lectures and laboratory activities, practical exercises and seminars by experts; opportunities for intensive tutoring and for master thesis-related stages of at least six months duration will be available with outstanding companies in the sector of the food industry or with other relevant organisations in the private or public sphere. The Programme assists students to find suitable internship opportunities with qualified laboratories in Italy and abroad.
Examinations are written or oral and assess students’ participation also through reports, presentations, and group work.
During the first year of the programme the student will acquire knowledge on animal and crop genomics, focusing on the most advanced methods for high throughput genomic analysis (transcriptomics, genome-wide SNP analysis, epigenomics) and on the most recent approaches for selective breeding (genomic selection, genomic prediction). In parallel, the student will learn how bioinformatics tools might be applied to manage large sets of data, how biological data bases are organized and how to link different types of data. Extensive practical training in bioinformatics will be offered with various sessions in a dedicated lab. Food-borne pathogens and the positive role of microorganisms in food processes will be examined in an integrated microbiology course, while the molecular basis of pathology, host-response to infection, epidemiology, and diagnostics of transmissible diseases will form the basis of two courses. A course on biotechnology for crop production will introduce the molecular and physiological basis of crop production. Biotechnological approaches to improve crop yield, with particular attention to fruit production, and to reduce impact of abiotic stresses will examined. Molecular tools for food traceability and an intensive practical lab in DNA/RNA/protein analysis applied to food control will conclude the first year.
In the second year, the first semester have three courses. One will focus on novel technologies (proteomics, metabolomics, nanotechnology) and their application to food production. A second one will extend knowledge on plant biotechnology exploring advanced technologies for crop disease and pest management. A third one will deal with contaminants in food and food legislation. The second semester is completely dedicated to lab internship. It is possible to join a research lab in the campus or to have a working stage in the private sector.
link to the Campus descriptions:
The University of Padova, the Veneto Region and other organisations offer various scholarship schemes to support students. Below is a list of the funding opportunities that are most often used by international students in Padova.
You can find more information below and on our website here: http://www.unipd.it/en/studying-padova/funding-and-fees/scholarships
You can find more information on fee waivers here: http://www.unipd.it/en/fee-waivers
Bioinformatics is a new scientific discipline with roots in computer science, statistics and molecular biology. It was developed to cope with the output of genome sequencing initiatives, that result in an ever-increasing amount of data available about DNA (public databases currently contain over 100 Gigabases of DNA), RNA and derived proteins. Bioinformaticians apply information technology to store, retrieve and manipulate these data and employ statistical methods capable of analysing large amounts of biological data to predict gene functions and to demonstrate the relationship between genes and proteins.
There is a world-wide lack in trained Bioinformaticians resulting in long lists of positions that remain open. Some years ago Wageningen University in the Netherlands started with one of the first fully dedicated MSc curricula in Bioinformatics. Graduates are already in high demand both in industry and in academic research including medical sciences.
On the programme of Bioinformatics page you can find the general outline of the programme and more detailed information about courses, theses and internships.
Depending on the candidate's skills and interest advanced courses in 3D protein modelling, genome annotation or in software design can be taken. The last part of the programme consists of a Bioinformatics thesis period of 6 months. Typical thesis projects include genome annotation, design and testing of mutant proteins, and development of new algorithms to facilitate protein domain recognition. The programme commences annually in September and February.
Bioinformatics is a new fast growing field of research poorly served by traditional curricula in Life Sciences. As the demand has outpaced the supply of bioinformaticians the first job after graduation is often a PhD project at a research institute or at an University in or outside the Netherlands. Read more about career perspectives and opportunities after finishing the programme.
In recent years, biological research has become increasingly interdisciplinary, focusing heavily on mathematical modeling and on the analysis of system-wide quantitative information. Sophisticated high-throughput techniques pose new challenges for data integration and data interpretation. The Computational Life Science (CompLife) MSc program at Jacobs University meets these challenges by covering computational, theoretical and mathematical approaches in biology and the life sciences. It is geared towards students of bioinformatics, computer science, physics, mathematics and related areas.
The CompLife program is located at Jacobs University, a private and international English-language academic institution in Bremen, Germany. CompLife students at Jacobs University take a tailor-made curriculum comprising lectures, seminars and laboratory trainings. Courses cover foundational as well as advanced topics and methods. Core components of the program and areas of specialization include:
- Computational Systems Biology
- Computational Physics and Biophysics
- RNA Biology
- Imaging and Modeling in Medicine
- Ecological Modeling
- Theoretical Biology
- Applied Mathematics
- Numerical Methods
For more details on the CompLife curriculum, please visit the program website at http://www.jacobs-university.de/complife.
Graduates of the CompLife program are prepared for a career in biotechnology and biomedicine. Likewise, graduates of the program are qualified to move on to a PhD.
The CompLife program starts in the first week of September every year. Please visit http://www.jacobs-university.de/graduate-admission or use the contact form to request details on how to apply. We are looking forward to receiving your inquiry.
All applicants are automatically considered for merit-based scholarships of up to € 12,000 per year. Depending on availability, additional scholarships sponsored by external partners are offered to highly gifted students. Moreover, each admitted candidate may request an individual financial package offer with attractive funding options. Please visit http://www.jacobs-university.de/study/graduate/fees-finances to learn more.
Jacobs University’s green and tree-shaded campus provides much more than buildings for teaching and research. It is home to an intercultural community which is unprecedented in Europe. A Student Activities Center, various sports facilities, a music studio, a student-run café/bar, concert venues and our Interfaith House ensure that you will always have something interesting to do. In addition, Jacobs University offers accommodation for graduate students on or off campus.
The only Master’s specialisation in the Netherlands covering the function of our epigenome, a key factor in regulating gene expression and in a wide range of diseases.
Our skin cells, liver cells and blood cells all contain the same genetic information. Yet these are different types of cells, each performing their own specific tasks. How is this possible? The explanation lies in the epigenome: a heritable, cell-type specific set of chromosomal modifications, which regulates gene expression. Radboud University is specialised in studying the epigenome and is the only university in the Netherlands to offer a Master’s programme in this field of research.
The epigenome consists of small and reversible chemical modifications of the DNA or histone proteins, such as methylation, acetylation and phosphorylation. It changes the spatial structure of DNA, resulting in gene activation or repression. These processes are crucial for our health and also play a role in many diseases, like autoimmune diseases, cancer and neurological disorders. As opposed to modifications of the genome sequence itself, epigenetic modifications are reversible. You can therefore imagine the great potential of drugs that target epigenetic enzymes, so-called epi-drugs.
In this specialisation, you’ll look at a cell as one big and complex system. You’ll study epigenetic mechanisms during development and disease from different angles. This includes studying DNA and RNA by next-generation sequencing (epigenomics) and analysing proteins by mass spectrometry (proteomics). In addition, you‘ll be trained to design computational strategies that allow the integration of these multifaceted, high-throughput data sets into one system.
- Radboud University combines various state-of-the-art technologies – such as quantitative mass spectrometry and next-generation DNA sequencing – with downstream bioinformatics analyses in one department. This is unique in Europe.
- This programme allows you to work with researchers from the Radboud Institute for Molecular Life sciences (RIMLS), one of the leading multidisciplinary research institutes within this field of study worldwide.
- We have close contacts with high-profile medically oriented groups on the Radboud campus and with international institutes (EMBL, Max-Planck, Marie Curie, Cambridge, US-based labs, etc). As a Master’s student, you can choose to perform an internship in one of these related departments.
- Radboud University coordinates BLUEPRINT, a 30 million Euro European project focusing on the epigenomics of leukaemia. Master’s students have the opportunity to participate in this project.
As a Master’s student of Medical Epigenomics you’re trained in using state-of-the art technology in combination with biological software tools to study complete networks in cells in an unbiased manner. For example, you’ll know how to study the effects of drugs in the human body.
When you enter the job market, you’ll have:
- A thorough background of epigenetic mechanisms in health and disease, which is highly relevant in strongly rising field of epi-drug development
- Extensive and partly hands-on experience in state-of-the-art ‘omics’ technologies: next-generation sequencing, quantitative mass spectrometry and single cell technologies;
- Extensive expertise in designing, executing and interpreting scientific experiments in data-driven research;
- The computational skills needed to analyse large ‘omics’ datasets.
With this background, you can become a researcher at a:
- University or research institute;
- Pharmaceutical company, such as Synthon or Johnson & Johnson;
- Food company, like Danone or Unilever;
- Start-up company making use of -omics technology.
Apart from research into genomics and epigenomics, you could also work on topics such as miniaturising workflows, improving experimental devices, the interface between biology and informatics, medicine from a systems approach.
Or you can become a:
- Biological or medical consultant;
- Biology teacher;
- Policy coordinator, regarding genetic or medical issues;
- Patent attorney;
- Clinical research associate;
Each year, the Molecular Biology department (Prof. Henk Stunnenberg, Prof. Michiel Vermeulen) and the Molecular Developmental Biology department (Prof. Gert-Jan Veenstra) at the RIMLS offer between five and ten PhD positions. Of course, many graduates also apply for a PhD position at related departments in the Netherlands, or abroad.
- Systems biology
In the Medical Epigenomics specialisation you won’t zoom in on only one particular gene, protein or signalling pathway. Instead, you’ll regard the cell as one complete system. This comprehensive view allows you to, for example, model the impact of one particular epigenetic mutation on various parts and functions of the cell, or study the effects of a drug in an unbiased manner. One of the challenges of this systems biology approach is the processing and integration of large amounts of data. That’s why you’ll also be trained in computational biology. Once graduated, this will be a great advantage: you’ll be able to bridge the gap between biology, technology and informatics , and thus have a profile that is desperately needed in modern, data-driven biology.
- Multiple OMICS approaches
Studying cells in a systems biology approach means connecting processes at the level of the genome (genomics), epigenome (epigenomics), transcriptome (transcriptomics), proteome (proteomics), etc. In the Medical Epigenomics specialisation, you’ll get acquainted with all these different fields of study.
- Patient and animal samples
Numerous genetic diseases are not caused by genetic mutations, but by epigenetic mutations that influence the structure and function of chromatin. Think of:
- Autoimmune diseases, like rheumatoid arthritis and lupus
- Cancer, in the forms of leukaemia, colon cancer, prostate cancer and cervical cancer
- Neurological disorders, like Rett Syndrome, Alzheimer, Parkinson, Multiple Sclerosis, schizophrenia and autism
We investigate these diseases on a cellular level, focusing on the epigenetic mutations and the impact on various pathways in the cell. You’ll get the chance to participate in that research, and work with embryonic stem cell, patient, Xenopus or zebra fish samples.
See the website http://www.ru.nl/masters/medicalbiology/epigenomics