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Masters Degrees (Prostate Cancer)

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If you are a healthcare professional, this course gives you the knowledge and expertise to develop as a specialist prostate cancer practitioner. Read more
If you are a healthcare professional, this course gives you the knowledge and expertise to develop as a specialist prostate cancer practitioner. Through a combination of online learning and (if appropriate) taught study days you learn how to provide, promote and develop high standards of care.

The postgraduate certificate stage focuses on developing your clinical knowledge and skills. The prostate cancer module gives you an in-depth understanding of managing the stages of the disease including:
-The physical and psychosocial impact.
-Treatment.
-The needs of those affected.
-How these needs can be addressed.

As advanced communication is essential to your clinical role, you take one of two modules on the subject. This helps you develop your knowledge of the concepts underpinning advanced communication strategies used in practice. If you choose to take the advanced communication skills in practice module, you have the opportunity to practice your communication skills during intensive role play, the key learning approach.

During the postgraduate diploma stage you develop your understanding of the wider specialist and advanced practice role in areas such as:
-Leadership.
-Peer support.
-Education.
-Service development and improvement.

You also expand your knowledge of high risk or high priority areas in practice such as:
-Care of African Caribbean men.
-Needs relating to sexual function.
-Survivorship.
-End of life care.

This stage of the course also prepares you for undertaking research by improving your understanding of research methods and helping you develop a research question for investigation.

In the final masters stage you research a specific area of interest relevant to your professional role and priorities in practice. This enables you to specialise in your chosen topic, develop expertise and hopefully influence practice or policy.

Throughout your studies you are encouraged to reflect on your role as:
-An ambassador for your patients and their families.
-A peer supporter for other healthcare professionals involved in caring for people affected by the disease.
-An educator.

You also evaluate your own practice and the practice of others to help you develop ideas for service improvement within your practice and workplace.

For more information, see the website: https://www.shu.ac.uk/study-here/find-a-course/mscpgdippgcert-prostate-cancer-care

Course delivery

This is primarily a distance learning course using online learning. You must have internet access and be prepared to engage with technology. We supply you with a range of online learning and teaching resources, including access to library resources and information databases.

Each module provides clear guidance on how to approach your self-directed study. This learning is enhanced by online, tutor facilitated group discussions allowing you to share views and practice experiences with other students. These sessions are a popular and valuable learning resource, and are also used to support you in your final marked assessment.

Professional recognition

Prostate Cancer UK is a registered charity in England and Wales (1005541) and in Scotland (SC039332). Registered company number 2653887.

Course structure

Distance learning – 3 years. Starts September and January.

The Postgraduate Certificate (PgCert) is achieved by successfully completing 60 credits. The Postgraduate Diploma (PgDip) is achieved by successfully completing 120 credits. The Masters (MSc) award is achieved by successfully completing 180 credits.

Postgraduate Certificate core modules
-Prostate cancer (15 credits)
-Advanced communication and information in supportive care (30 credits)

Postgraduate Diploma core modules
-Advancing practice in prostate cancer care (30 credits)
-Research methods for practice (15 credits)

Masters
-Dissertation (60 credits)

Optional modules (you choose a further 30 credits from the following modules)
-Loss, grief and bereavement (15 credits)
-Complexities in symptom management (15 credits)
-Collaborative working in supportive care (15 credits)
-Informed consent in healthcare practice (15 credits)
-Evidencing your continuing professional development (15 credits)

Assessment: online activities and discussion; essays; project and research work; presentations.

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If you want to pursue a research career in academia or industry, our MSc Cancer Biology will provide you with the essential advanced skills and knowledge for a role in biopharma, healthcare or cancer research. Read more
If you want to pursue a research career in academia or industry, our MSc Cancer Biology will provide you with the essential advanced skills and knowledge for a role in biopharma, healthcare or cancer research. We offer many opportunities for you to explore medically relevant research in the School of Biological Sciences including hospital-based sessions through our collaboration with local cancer specialists and clinicians.

An important and exciting part of your programme is an extensive independent research project, based in one of our academic research groups using advanced laboratories facilities and bioinformatics tools. There are also opportunities for research projects to take place within an industrial or clinical setting.

Throughout the course, you develop your knowledge in the essential areas of molecular and cellular biology which complement your specialist modules in cancer biology. You gain expertise in areas including:
-Specific cancer types (including breast, prostate, pancreatic and colon cancer)
-Clinical aspects of cancer
-Emerging trends in cancer research

You are also trained in modern research methods and approaches which will develop your skills in complex biological data analysis and specific techniques in cancer research.

Within our School of Biological Sciences, two-thirds of our research is rated “world-leading” or “internationally excellent” (REF 2014), and you will learn from and work alongside our expert staff as you undertake your own research.

Our expert staff

We have a very strong research team in the area of cancer biology, who are well placed to deliver the specialist teaching on this course.

The team includes the course leader Professor Elena Klenova (molecular oncology and cancer biomarkers), Dr Ralf Zwacka (apoptotic and survival signalling in cancer), Dr Greg Brooke (steroid hormone receptor signalling in cancer), Dr Metodi Metodiev (clinical proteomics and bioinformatics), Dr Pradeepa Madapura (cancer epigenetics), Dr Vladimir Teif (computational and systems biology), Professor Nelson Fernandez (tumour immunology) and Dr Filippo Prischi (structural biology and biophysics of novel drug targets).

External experts also input to your teaching, including guest speakers from hospitals and research institutions, who deliver classes both on-campus and within the hospital environment.

As one of the largest schools at Essex, we offer a lively, friendly and supportive environment with research-led study and high-quality teaching, and you benefit from our academics’ wide range of expertise and research.

The University of Essex has a Women's Network to support female staff and students and was awarded the Athena SWAN Institutional Bronze Award in November 2013 in recognition of its continuing work to support women in STEM.

Specialist facilities

Recent investment has provided modern facilities for functional genomics, computational biology and imaging biological systems. On our course you have the opportunity to:
-Study in an open and friendly department, with shared staff-student social spaces
-Carry out your research project in shared lab space, alongside PhD students and researchers engaged in cutting-edge cancer research
-Learn to use state-of-the-art research facilities, including an advanced microscopy suite, proteomics laboratory, cell culture, bioinformatics and genomics facilities, modern molecular biology laboratories, and protein structure analysis

Your future

Graduates who are skilled in the research methods embedded into your course are in demand from the biotechnology and biomedical research industries in this area of the UK and beyond.

Many of our Masters students progress to study for a PhD, and there are many opportunities within our school leading to a career in science.

We work with our University’s Employability and Careers Centre to help you find out about further work experience, internships, placements, and voluntary opportunities.

Example structure

-Advanced Cancer Biology
-Practical Skills in Cancer Research
-Gene Technology and Synthetic Biology
-Protein Technologies
-Professional Skills and the Business of Molecular Medicine
-Cancer Biology (optional)
-Research Project: MSc Cancer Biology
-Genomics (optional)
-Cell Signalling (optional)
-Molecular Medicine and Biotechnology (optional)
-Human Molecular Genetics (optional)
-Molecular and Developmental Immunology (optional)
-Creating and Growing a New Business Venture (optional)
-Rational Drug Design (optional)

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If you are a therapeutic radiographer or another healthcare professional working within radiotherapy and oncology, this course offers you the opportunity to progress in your specialism. Read more
If you are a therapeutic radiographer or another healthcare professional working within radiotherapy and oncology, this course offers you the opportunity to progress in your specialism. The modules cover a wide range of topics relevant to this area of clinical practice, allowing you to tailor the course to your own career development needs.

Some of the modules you can take are radiotherapy specific, while others take a wider perspective and look at the interdisciplinary nature of approaches in oncology. All modules are designed to support your continuing professional development and the development of skills needed to plan and evidence this.

Opportunities for both independent study and work-based learning are included as part of the course structure. Both allow you to negotiate learning objectives that can be centred on your own area of interest within the workplace.

You may also be eligible to apply for accreditation of work-based projects and prior certificated learning, which will count towards your final award. Please contact us for more information.

For more information, see the website: https://www.shu.ac.uk/study-here/find-a-course/mscpgdippgcert-radiotherapy-and-oncology

Study individual modules

You can study individual modules from this course and gain academic credit towards a qualification. Visit our continuing professional development website for more information: http://www4.shu.ac.uk/faculties/hwb/cpd/modules/

Professional recognition

The course is accredited by the College of Radiographers.

Course structure

Distance learning - 3 years. Starts September and January.

Course structure
The Postgraduate Certificate (PgCert) is achieved by successfully completing 60 credits. The Postgraduate Diploma (PgDip) is achieved by successfully completing 120 credits. The masters (MSc) award is achieved by successfully completing 180 credits.

Postgraduate Certificate core modules
-Fundamentals of radiotherapy and oncology practice (15 credits)
-Professional practice portfolio (15 credits)
-Plus a further 30 credits from the optional module list below.

Postgraduate Diploma core modules
-Research methods for practice (15 credits)
-Personalised study module or work based learning for service development modules (15 credits)
-Plus a further 30 credits from the optional module list below.

Masters
-Dissertation (60 credits)

Optional modules
-Technical advances in radiotherapy (15 credits)
-Informed consent in healthcare practice (15 credits)
-Image guided radiotherapy (15 credits)
-Brachytherapy: principles in practice (15 credits)
-Evidencing your CPD (15 credits)
-Prostate cancer (15 credits)
-Breast cancer radiotherapy (15 credits)
-Loss, grief and bereavement (15 credits)
-Advanced planning (30 credits)
-Fundamentals of radiotherapy planning (30 credits)
-Advancing practice in prostate cancer care (30 credits)
-Advanced communication and information in supportive care (30 credits)
-Psychology of cancer care (30 credits)
-Expert practice (30 credits)
-End of life decision making (30 credits)
-Head and neck cancer (15 credits)
-Collaborative working in supportive and palliative care (15 credits)
-Complexities of symptom management (15 credits)

Assessment
We use various assessment methods, supporting the development of both your academic and professional skills.Short online activities are used to promote engagement with the distance learning materials, provide support for the final assignment and facilitate online discussion with fellow peers on the module. Other methods of assessment include: essays; business cases or journal article; project and research work; poster and PowerPoint presentation; case studies; service improvement proposal and plans; critical evaluations; profiles of evidence; planning portfolio.

Other admission requirements

You must also have: access to and the ability to use IT software such as Word and PowerPoint; access to a computer with reliable internet access; confidence in accessing and using web-based materials. We determine you suitability for the course and your ability to complete it through your application, references and CV. You may also have an advisory interview with the course leader or nominated tutor to: ascertain your needs and aspirations; decide on a course of study; give you guidance to prepare for any claims for credit through our accreditation of prior certificated learning (APCL) or accreditation of prior experiential learning (APEL) procedures.

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Clinicians, scientists and students engaged in cancer research at Newcastle share a common purpose. to improve treatment outcomes for patients with cancer. Read more

Programme Overview

Clinicians, scientists and students engaged in cancer research at Newcastle share a common purpose: to improve treatment outcomes for patients with cancer. Work covers a broad spectrum - understanding the biological and molecular differences between normal and malignant cells and using this knowledge to develop new anti-cancer drugs.

Research Supervision

Exploratory biology, target and biomarker discovery
Molecular genetic and mechanistic studies are used to identify critical molecular changes in cancer and their relevance to disease development and progression, and to validate these as biomarkers and targets for therapeutic intervention. A wide range of contemporary genomic, bioinformatic, molecular biology, biochemical and cell biology techniques are used.

Studies focus on haematological malignancies (leukaemia and lymphoma), paediatric solid tumours (neuroblastoma and medulloblastoma), and adult solid tumours (eg breast, ovarian, prostate, bladder and liver cancers).

Drug development
The exploitation of novel targets is achieved by the use of rational drug design, notably the use of structure-based design, in conjunction with medium-throughput screening. Target molecule synthesis and multiple parallel synthesis approaches are used for lead optimisation, and candidate drugs are evaluated in cell-free and whole cell target-based assays.

Biomarker development
We exploit critical molecular defects as biomarkers to enhance disease detection and diagnosis, prediction of disease course, sensitivity to specific drugs and therapeutic monitoring. We play leading roles in molecular diagnostics, biomarker assessment and therapeutic monitoring for national and international clinical trials.

Clinical trials
Clinical trials (Phase I/II/III) are undertaken in both adults and children. Trials have a strong hypothesis-testing translational research component and are performed under the auspices of national or international research networks (eg CR–UK, CCLG, EORTC), as well as directly in collaboration with the pharmaceutical industry.

Training and Skills

As a research student you will receive a tailored package of academic and support elements to ensure you maximise your research and future career. The academic information is in the programme profile and you will be supported by our Faculty of Medical Sciences Graduate School.

For further information see http://www.ncl.ac.uk/postgraduate/courses/degrees/cancer-mphil-phd-md/#training&skills

How to apply

For course application information see http://www.ncl.ac.uk/postgraduate/courses/degrees/cancer-mphil-phd-md/#howtoapply

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If you are a practitioner working in an extended role or at an advanced practice level in your clinical field, this course is designed to help you develop your practice. Read more
If you are a practitioner working in an extended role or at an advanced practice level in your clinical field, this course is designed to help you develop your practice. You can tailor course content to reflect your evolving scope of practice, individual development needs and service requirements.

You critically evaluate theoretical perspectives and relevant research to help inform and underpin your clinical decision-making and develop your ability to work collaboratively across professional boundaries.

The course improves your independent and active learning ability, so you can:
-Advance your knowledge, understanding and skills.
-Review and enhance your own and others practice.
-Develop your management of complex issues and problems.
-Lead practice developments.

It also supports and enables you to work towards developing a profile that satisfies professional body requirements for advanced practice (for UK practitioners) and statutory requirements for continuing professional development (CPD). This may also meet the requirements of advanced practice in other countries, which increases your employability and career potential. It is a requirement for all students to have a tripartite agreement with employer support to undertake the course. You must be in a role where there is an opportunity to practice advanced skills under the guidance and mentorship of someone appropriately qualified.

Study individual modules

You can study individual modules from this course and gain academic credit towards a qualification. Visit our continuing professional development website for more information: http://www.shu.ac.uk/faculties/hwb/cpd/modules.html

Professional recognition

The course is recognised by the College of Radiographers for the purposes of professional accreditation.

Course structure

Distance learning – 3 years. A mix of e-learning and work-based learning although you can study optional taught modules. Starts January and September

Course structure
The Postgraduate Certificate (PgCert) is achieved by successfully completing 60 credits. The Postgraduate Diploma (PgDip) is achieved by successfully completing 120 credits. The Masters (MSc) award is achieved by successfully completing 180 credits.

Postgraduate Certificate core modules
-Expert practice (30 credits)
-Plus a further 30 credits of optional module list below

Postgraduate Diploma core modules
-Advancing practice (15 credits)
-Research methods for practice (15 credits)
-Personalised study module or work-based learning for service development (15 credits)
-Plus a further 15 credits from the optional module list below

Options
-Informed consent in healthcare practice (15 credits)
-Evidencing your CPD (15 credits)
-Prostate cancer (15 credits)
-Technical advances in radiotherapy (15 credits)
-Image guided radiotherapy (15 credits)

MSc
-Dissertation (60 credits)

Assessment: demonstrate clinical competencies in your field of expertise; individually negotiated assignment; portfolio; outline; business case; journal article; oral viva.

Other admission requirements

We consider applicants on an individual basis. To be accepted, you need to satisfy the course leader that you have an ability to complete the course. A telephone conversation may be arranged with the course leader to discuss your role and the suitability of the course, before a place is offered.

You must be prepared to be intellectually challenged and to reflect on your clinical practice and consider how it may be improved based on critical evaluation. You need to be motivated, able to contribute to the online discussion and debate, and be prepared to study independently to explore the research literature that underpins practice.

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This course is for therapeutic radiographers and will enable you to develop your professional knowledge and enhance your clinical and research skills. Read more
This course is for therapeutic radiographers and will enable you to develop your professional knowledge and enhance your clinical and research skills. The modules on this course have been selected with the development and progression of the therapeutic radiography profession in mind.

Teaching, learning and assessment

The teaching and assessment strategies will enable you to develop your full potential by recognising and building on prior knowledge and experience and by facilitating development of subject-related and transferable skills. There are various forms of assessment including case study analysis, portfolio of evidence of practice, essays, written examination and a project containing evidence of research methods and analysis will be used to monitor your progress. Class sizes for attendance based modules are normally around 8-10 students. This ensures that students receive excellent support from tutors and benefit from sharing experiences with peers.

Teaching hours and attendance

Each module which you study on campus will require you to attend classes and carry out independent work. Your attendance at QMU will depend on which module you are studying.

Links with industry/professional bodies

On graduation you will be accredited by the Society and College of Radiographers.

Modules

The full MSc Radiotherapy award of 180 credits will require study of two modules of 90 credits - Research Methods (30 credits), a project (60 credits), and the remaining 90 credits to be taken from the following modules:

30 credits (distance learning): Emerging Technologies in Radiotherapy/ Management of Prostate Cancer/ Management of Breast Cancer

30 credits: Radiotherapy Verification and Analysis/Decision Taking in Radiotherapy Planning for Palliative Cancers/Decision Taking in Radiotherapy Planning for Breast Cancer/ The Principles of Gynaecological Brachytherapy/ The Clinical Practice of Vaginal Vault Brachytherapy/Planning and Delivery of Gynaecological Brachytherapy/ Ultrasound Localisation Procedures for Intrauterine Brachytherapy Insertions/ 3-D Computerised Tomography (CT) Treatment Planning for Vaginal Vault Brachytherapy/ Imaging Modalities (Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography for Therapeutic Radiographers/Image Interpretation and Pattern Recognition for Therapeutic Radiographers (choice of Abdomen/Pelvis – Thorax/CNS-Head/ Neck)/Independent Study/ Current Developments

15 credits : The Principals of Gynaecological Brachytherapy/Leading in Healthcare/Managing Change in Healthcare/Independent Study

Careers

This course is part of continuing professional development and is designed to improve the delivery of the service. Gaining this qualification may enhance your career prospects within the profession of radiography.

Quick Facts

- This course is accredited by the Society and College of Radiographers.
- The course offers advanced practice modules.
- The course offers a flexible approach to learning.

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If you are a therapeutic radiographer, dosimetrist or other healthcare professional working in radiotherapy and oncology, this course can help you develop your knowledge of radiotherapy planning. Read more
If you are a therapeutic radiographer, dosimetrist or other healthcare professional working in radiotherapy and oncology, this course can help you develop your knowledge of radiotherapy planning. It’s a highly focused course that gives you a thorough understanding of the key practices surrounding simulating and evaluating radiation doses for radiotherapy.

You gain an in-depth understanding of current and future radiotherapy planning issues and, crucially, develop the ability to apply critical thinking skills to practice. You gain general critical thinking and literature skills as well as more specific planning theory and plan evaluation skills.

Your studies cover core modules involving fundamental planning theories, plan evaluation, advanced planning and image guided radiotherapy. We also introduce you to research skills, which you use to produce a final dissertation.

The course is delivered using our virtual learning environment, known as Blackboard. You don't need to attend the university and you can study via the web in your own time, which means you can fit the course around your clinical work. The web-based learning materials are designed to help improve your radiotherapy knowledge, as well as share experiences with other students through our e-based discussion forum. If you are not confident with computers, help and support is available.

For some modules there is a requirement to produce a plan for the course and you must have access to a clinical radiotherapy planning environment. This helps support the demands of your postgraduate work.

You may be eligible to apply for accreditation of work-based projects and prior certificated learning, which will count towards your final award.

For more information, see the website: https://www.shu.ac.uk/study-here/find-a-course/mscpgdippgcert-radiotherapy-planning

Study individual modules

You can study individual modules from our courses and gain academic credit towards a qualification. Visit our continuing professional development website for detailed information about the modules we offer.

Professional recognition

This course is accredited by the College of Radiographers.

Course structure

Distance learning – typically 3 years. Starts September and January.

Course structure
The Postgraduate Certificate (PgCert) is achieved by successfully completing 60 credits.
The Postgraduate Diploma (PgDip) is achieved by successfully completing 120 credits.
The Masters (MSc) award is achieved by successfully completing 180 credits.

Postgraduate Certificate core modules
-Fundamentals of radiotherapy planning (30 credits)
-Image guided radiotherapy (15 credits)
-Plus a further 15 credits from the optional modules list below.

Postgraduate Diploma core modules
-Advanced radiotherapy planning (30 credits)
-Research methods for practice (15 credits)
-Plus a further 15 credits from optional module list below.

Masters
-Dissertation (60 credits)

Optional modules
-Personalised study module or work-based learning for service development (15 credits)
-Technical advances in radiotherapy (15 credits)
-Breast cancer radiotherapy (15 credits)
-Prostate cancer (15 credits)
-Head and neck cancer (15 credits)
-Expert practice (30 credits)
-Brachytherapy: principles to practice (15 credits)
-Fundamentals of radiotherapy and oncology practice (15 credits)

Assessment
We use various assessment methods, supporting the development of both your academic and professional skills. Short online activities are used to promote engagement with the distance learning materials, provide support for the final assignment and facilitate online discussion with fellow peers. Other methods of assessment include: essays; business cases or journal article; project and research work; poster and PowerPoint presentation; case studies; service improvement proposal and plans; critical evaluations; profiles of evidence; planning portfolio.

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The only Master’s specialisation in the Netherlands covering the function of our epigenome, a key factor in regulating gene expression and in a wide range of diseases. Read more

Master's specialisation in Medical Epigenomics

The only Master’s specialisation in the Netherlands covering the function of our epigenome, a key factor in regulating gene expression and in a wide range of diseases.
Our skin cells, liver cells and blood cells all contain the same genetic information. Yet these are different types of cells, each performing their own specific tasks. How is this possible? The explanation lies in the epigenome: a heritable, cell-type specific set of chromosomal modifications, which regulates gene expression. Radboud University is specialised in studying the epigenome and is the only university in the Netherlands to offer a Master’s programme in this field of research.

Health and disease

The epigenome consists of small and reversible chemical modifications of the DNA or histone proteins, such as methylation, acetylation and phosphorylation. It changes the spatial structure of DNA, resulting in gene activation or repression. These processes are crucial for our health and also play a role in many diseases, like autoimmune diseases, cancer and neurological disorders. As opposed to modifications of the genome sequence itself, epigenetic modifications are reversible. You can therefore imagine the great potential of drugs that target epigenetic enzymes, so-called epi-drugs.

Big data

In this specialisation, you’ll look at a cell as one big and complex system. You’ll study epigenetic mechanisms during development and disease from different angles. This includes studying DNA and RNA by next-generation sequencing (epigenomics) and analysing proteins by mass spectrometry (proteomics). In addition, you‘ll be trained to design computational strategies that allow the integration of these multifaceted, high-throughput data sets into one system.

Why study Medical Epigenomics at Radboud University?

- Radboud University combines various state-of-the-art technologies – such as quantitative mass spectrometry and next-generation DNA sequencing – with downstream bioinformatics analyses in one department. This is unique in Europe.
- This programme allows you to work with researchers from the Radboud Institute for Molecular Life sciences (RIMLS), one of the leading multidisciplinary research institutes within this field of study worldwide.
- We have close contacts with high-profile medically oriented groups on the Radboud campus and with international institutes (EMBL, Max-Planck, Marie Curie, Cambridge, US-based labs, etc). As a Master’s student, you can choose to perform an internship in one of these related departments.
- Radboud University coordinates BLUEPRINT, a 30 million Euro European project focusing on the epigenomics of leukaemia. Master’s students have the opportunity to participate in this project.

Career prospects

As a Master’s student of Medical Epigenomics you’re trained in using state-of-the art technology in combination with biological software tools to study complete networks in cells in an unbiased manner. For example, you’ll know how to study the effects of drugs in the human body.
When you enter the job market, you’ll have:
- A thorough background of epigenetic mechanisms in health and disease, which is highly relevant in strongly rising field of epi-drug development
- Extensive and partly hands-on experience in state-of-the-art ‘omics’ technologies: next-generation sequencing, quantitative mass spectrometry and single cell technologies;
- Extensive expertise in designing, executing and interpreting scientific experiments in data-driven research;
- The computational skills needed to analyse large ‘omics’ datasets.

With this background, you can become a researcher at a:
- University or research institute;
- Pharmaceutical company, such as Synthon or Johnson & Johnson;
- Food company, like Danone or Unilever;
- Start-up company making use of -omics technology.

Apart from research into genomics and epigenomics, you could also work on topics such as miniaturising workflows, improving experimental devices, the interface between biology and informatics, medicine from a systems approach.

Or you can become a:
- Biological or medical consultant;
- Biology teacher;
- Policy coordinator, regarding genetic or medical issues;
- Patent attorney;
- Clinical research associate;

PhD positions at Radboud University

Each year, the Molecular Biology department (Prof. Henk Stunnenberg, Prof. Michiel Vermeulen) and the Molecular Developmental Biology department (Prof. Gert-Jan Veenstra) at the RIMLS offer between five and ten PhD positions. Of course, many graduates also apply for a PhD position at related departments in the Netherlands, or abroad.

Our approach to this field

- Systems biology
In the Medical Epigenomics specialisation you won’t zoom in on only one particular gene, protein or signalling pathway. Instead, you’ll regard the cell as one complete system. This comprehensive view allows you to, for example, model the impact of one particular epigenetic mutation on various parts and functions of the cell, or study the effects of a drug in an unbiased manner. One of the challenges of this systems biology approach is the processing and integration of large amounts of data. That’s why you’ll also be trained in computational biology. Once graduated, this will be a great advantage: you’ll be able to bridge the gap between biology, technology and informatics , and thus have a profile that is desperately needed in modern, data-driven biology.

- Multiple OMICS approaches
Studying cells in a systems biology approach means connecting processes at the level of the genome (genomics), epigenome (epigenomics), transcriptome (transcriptomics), proteome (proteomics), etc. In the Medical Epigenomics specialisation, you’ll get acquainted with all these different fields of study.

- Patient and animal samples
Numerous genetic diseases are not caused by genetic mutations, but by epigenetic mutations that influence the structure and function of chromatin. Think of:
- Autoimmune diseases, like rheumatoid arthritis and lupus
- Cancer, in the forms of leukaemia, colon cancer, prostate cancer and cervical cancer
- Neurological disorders, like Rett Syndrome, Alzheimer, Parkinson, Multiple Sclerosis, schizophrenia and autism

We investigate these diseases on a cellular level, focusing on the epigenetic mutations and the impact on various pathways in the cell. You’ll get the chance to participate in that research, and work with embryonic stem cell, patient, Xenopus or zebra fish samples.

See the website http://www.ru.nl/masters/medicalbiology/epigenomics

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