This Clinical Pharmacology degree programme offers focused training which integrates basic and clinical sciences, and equips students with the essential skills required to function effectively as a clinical pharmacologist in the 21st century. As a student on the MSc Clinical Pharmacology programme, you will acquire core skills, enabling an appreciation of how to apply clinical pharmacological, regulatory and ethical principles to the optimisation of therapeutic practice and clinical research. Crucially, in addition to a firm grasp of the principles of molecular pharmacology, you will also gain foundational knowledge in the emerging science of pharmacogenomics and personalised medicine.
You will attend lectures, seminars and tutorials and take part in lab, project and team work.
In addition you will undertake a dissertation/project.
Career opportunities include positions in academia, health care and the pharmaceutical industry; returning to more advanced positions within a previous clinical environment (eg pharmacicts, clinicians); and PhD study.
Stratified Medicine holds huge potential in the timely development of new treatments for human disease. It is among the most important concepts to emerge in 21st century clinical science and will be a crucial component of the global drive to increase the efficacy, safety and cost effectiveness of new treatments. This taught postgraduate Masters programme draws on the current and future needs of the Life Sciences sector, to create a highly skilled workforce. It harnesses Scotland’s strengths in Stratified Medicine, Clinical Trials, Bioinformatics and Pharmacogenomics to provide focused training which integrates basic and clinical sciences, and equips students with grounding in the essential skills required to design, execute and evaluate modern clinical interventions.
Students will undertake core courses which will account for 90 credits and a further 30 credits from options, which will enable students to personalise their degree to better align it with their future career aspirations. Students will also be offered a choice of project.
Project and assessment
The project will account for the remaining 60 credits. The programme will include an opportunity for all students to present the outcomes of their projects to an audience of other students and academics. Assessment will consist of submission of a dissertation and a viva examination.
Graduates of this programme will be competitive applicants for the positions in the commercial life sciences sector, or for PhD study in an academic or combined commercial/academic environment.
The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents.
The programme provides a thorough grounding in modern approaches to the understanding of the genetics of disease alongside the cutting-edge research methods and techniques used to advance our understanding of development of disease. Core modules provide a broad coverage of the genetics of disease, research skills and social aspects, whilst specialised streams in Inherited Diseases, Pharmacogenetics and Computational Genomics, in which students can qualify, and the research project allow more in-depth analysis in areas of genetics.
Students undertake modules to the value of 180 credits.
The programme consists of four core modules (60 credits) and two specialist modules (30 credits) and a research project culminating in a dissertation (90 credits).
A Postgraduate Diploma consisting of six modules (four core modules in term one and two modules within the selected stream in term two) is offered, full-time nine months.
A Postgraduate Certificate consisting of four core modules in term one (60 credits) is offered, full-time three months.
In term two you will take specialist modules depending on the specialist stream you select: Inherited Disease (A); Pharmacogenetics (B); Computational Genomics (C).
Students undertake an original research project investigating topical questions in genetics and genetics of human disease which culminates in a dissertation of 12,000 to 14,000 words and an oral presentation.
Teaching and learning
Students develop their knowledge and understanding of genetics of human diseases through a combination of lectures, seminars, tutorials, presentations and journal clubs. Taught modules are assessed by unseen written examination and/or, written reports, oral presentations and coursework. The research project is assessed by the dissertation and oral presentation.
Further information on modules and degree structure available on the UCL Genetics Institute website.
Further information on modules and degree structure is available on the department website: Genetics of Human Disease MSc
Advanced training in genetic techniques including bioinformatic and statistical approaches positions graduates well for PhD studentships in laboratories using genetic techniques to examine diseases such as heart disease, cancer and neurological disorders. Another large group will seek research jobs in the pharmaceutical industry, or jobs related to genetics in healthcare organisations.
Recent career destinations for this degree
The MSc in Genetics of Human Disease facilitates acquisition of knowledge and skills relevant to a career in research in many different biomedical disciplines. About half of our graduates enter a research career by undertaking and completing PhDs and working as research associates/scientists in academia. Some of our graduates go on to jobs in the pharmaceutical industry, while others enter careers with clinical genetic diagnosis services, particularly in molecular genetics, in healthcare organisations and hospitals around the world. Those graduates with a prior medical training often utilise their new skills as clinical geneticists.
Careers data is taken from the ‘Destinations of Leavers from Higher Education’ survey undertaken by HESA looking at the destinations of UK and EU students in the 2013–2015 graduating cohorts six months after graduation.
UCL is in a unique position to offer both the basic science and application of modern genetics to improve human health. The programme is a cross-faculty initiative with teaching from across the School of Life and Medical Sciences (SLMS) at UCL.
Students will be based at the UCL Genetics Institute (UGI), a world-leading centre which develops and applies biostatistical and bioinformatic approaches to human and population genetics. Opportunities to conduct laboratory or computational-based research projects are available in the laboratories of world-leading geneticists affiliated to the UGI.
The Research Excellence Framework, or REF, is the system for assessing the quality of research in UK higher education institutions. The 2014 REF was carried out by the UK's higher education funding bodies, and the results used to allocate research funding from 2015/16.
The following REF score was awarded to the department: Division of Biosciences
82% rated 4* (‘world-leading’) or 3* (‘internationally excellent’)
Learn more about the scope of UCL's research, and browse case studies, on our Research Impact website.
We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments.
As a student you will be registered with a University research institute, for many this is the Institute for Cellular Medicine (ICM). You will be supported in your studies through a structured programme of supervision and training via our Faculty of Medical Sciences Graduate School.
We undertake the following areas of research and offer MPhil, PhD and MD supervision in:
Newcastle hosts one of the most comprehensive organ transplant programmes in the world. This clinical expertise has developed in parallel with the applied immunobiology and transplantation research group. We are investigating aspects of the immunology of autoimmune diseases and cancer therapy, in addition to transplant rejection. We have themes to understand the interplay of the inflammatory and anti-inflammatory responses by a variety of pathways, and how these can be manipulated for therapeutic purposes. Further research theme focusses on primary immunodeficiency diseases.
There is strong emphasis on the integration of clinical investigation with basic science. Our research include:
We also research the effects of UVR on the skin including mitochondrial DNA damage as a UV biomarker.
This area emphasises on translational research, linking clinical- and laboratory-based science. Key research include:
Focus is on applied research and aims to underpin future clinical applications. Technology-oriented and demand-driven research is conducted which relates directly to health priority areas such as:
This research is sustained through extensive internal and external collaborations with leading UK and European academic and industrial groups, and has the ultimate goal of deploying next-generation diagnostic and therapeutic systems in the hospital and health-care environment.
There is a number of research programmes into the genetics, immunology and physiology of kidney disease and kidney transplantation. We maintain close links between basic scientists and clinicians with many translational programmes of work, from the laboratory to first-in-man and phase III clinical trials. Specific areas:
We have particular interests in:
Novel non-invasive methodologies using magnetic resonance are developed and applied to clinical research. Our research falls into two categories:
Our studies cover a broad range of topics (including diabetes, dementia, neuroscience, hepatology, cardiovascular, neuromuscular disease, metabolism, and respiratory research projects), but have a common theme of MR technical development and its application to clinical research.
We focus on connective tissue diseases in three, overlapping research programmes. These programmes aim to understand:
This research theme links with other local, national and international centres of excellence and has close integration of basic and clinical researchers and hosts the only immunotherapy centre in the UK.
Genetic approaches to the individualisation of drug therapy, including anticoagulants and anti-cancer drugs, and in the genetics of diverse non-Mendelian diseases, from diabetes to periodontal disease, are a focus. A wide range of knowledge and experience in both genetics and clinical sciences is utilised, with access to high-throughput genotyping platforms.
Our scientists and clinicians use in situ cellular technologies and large-scale gene expression profiling to study the normal and pathophysiological remodelling of vascular and uteroplacental tissues. Novel approaches to cellular interactions have been developed using a unique human tissue resource. Our research themes include:
We also have preclinical molecular biology projects in breast cancer research.
We conduct a broad range of research activities into acute and chronic lung diseases. As well as scientific studies into disease mechanisms, there is particular interest in translational medicine approaches to lung disease, studying human lung tissue and cells to explore potential for new treatments. Our current areas of research include:
Our research projects are concerned with the harmful effects of chemicals, including prescribed drugs, and finding ways to prevent and minimise these effects. We are attempting to measure the effects of fairly small amounts of chemicals, to provide ways of giving early warning of the start of harmful effects. We also study the adverse side-effects of medicines, including how conditions such as liver disease and heart disease can develop in people taking medicines for completely different medical conditions. Our current interests include: environmental chemicals and organophosphate pesticides, warfarin, psychiatric drugs and anti-cancer drugs.
Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.
Our MSc in Genomic Medicine is accredited by Health Education England and designed to fulfil the aspirations of the 100,000 Genome Project to create a world-class NHS workforce that understands and applies genomics for patient care.
This course is ideal whether you are a member of NHS staff or a science graduate. NHS professionals will learn how genomics impact on their area of clinical practice, while science graduates will receive training to help them gain employment in the healthcare sector (eg as a biomedical scientist or in genomic counselling) or pursue a PhD in the field.
We emphasise the practice of genomics and bioinformatics in the NHS and academia as a partnership between multiple stakeholders, including clinical, academic and industrial involvement.
As such, you will learn from clinical experts from the Manchester Centre for Genomic Medicine , The University of Manchester, Liverpool University, Public Health England, AstraZeneca and Qiagen.
Our MSc consists of taught units and a literature review or a bioinformatics-based project. You will be encouraged to use your intellectual curiosity, creativity and critical thinking in the practical application of genomics and bioinformatics.
MRes students will write a literature review and a research proposal (project 1) before going on to complete a six-month practical research project.
We take a student-focused and patient-centred approach to teaching and learning.
The course content is delivered using a combination of online and face-to-face methods including lectures, problem and evidence-based learning, workshops and collaborative learning.
The face-to-face elements are designed to help you develop the deeper contextualised specialist knowledge and critical evaluative skills necessary for a questioning and innovative approach to your learning and clinical practice.
You will learn from healthcare professionals and industry partners who are working at the forefront of practice and clinical research and can draw on their scholarship and expertise to help you build your knowledge.
If you choose to study the MRes qualification, the 25-week lab-based research project will provide excellent practical training in a number of research methods and techniques.
The MSc is divided into 15-credit core and optional units. Full-time students will normally do a 60-credit research project, and part-time students a 30-credit literature review.
We collaborate with the following organisations to deliver this MSc:
"So far, I have completed four modules on Bioinformatics, Human Genetics, Pharmacogenomics and Genetic Counselling. I can honestly say that I have thoroughly enjoyed each of these and they have opened my eyes to the potential transformation of healthcare in the NHS through genomic medicine."
Bradley Horn, Genetic Technologist
Practical support and advice for current students and applicants is available from the Disability Advisory and Support Service .
Several units from this MSc can be taken as standalone courses for continuing professional development (CPD). Please visit the Genomic Medicine (CPD units) page for further information.
Our course is designed to support and upskill healthcare professionals working in the NHS in areas where genomic medicine is becoming part of clinical practice.
Our science graduates have gone on to apply their new skills in service labs in their home countries, gained employment in the NHS, undertaken further study for genomic counselling, or have continued their research to pursue a PhD in the field.
This course is accredited by Health Education England.
Our flexible, blended MSc Molecular Pathology course will enable you to take advantage of growing opportunities within this field, which is critically important for translational medicine, both in cancer and non-cancer diseases.
The number of academic pathologists trained in molecular pathology has steadily declined over the past 20 years. As such, it has been identified as an area requiring support and development by the Medical Research Council (MRC) and the Royal College of Pathologists, creating careers opportunities for students and professionals alike.
Our master's course is aimed at medical students, biomedical scientists, medical practitioners and trainee pathologists who want to learn more about molecular pathology. Trainee pathologists can take our course as part of an existing training programme.
You will benefit from a unique focus on the molecular analysis of tissue samples and take optional units in various areas of laboratory medicine and emerging diagnostic methods, such as proteomics and chemical pathology.
Students will also become part of Manchester's world leading precision medicine research community, learning practical skills that will be directly applicable to this emerging field.
In addition, you will benefit from our association with the network of MRC and Engineering and Physical Sciences Research Council funded Molecular Pathology nodes, which have been partly established to train more scientists to work in this field. This will enable you to connect with colleagues and related opportunities across the UK.
This course aims to provide you with a wide and detailed understanding of the various aspects of molecular pathology.
Provided as part of The University of Manchester MRC/EPSRC Molecular Pathology node (Manchester Molecular Pathology Innovation Centre), we recognise the need for providing more training in molecular pathology among histopathology trainees, clinical scientists and biomedical scientists.
As such, the course addresses a wide audience, and has a broad range of both core and non-core course units to facilitate the different learning and training needs of different groups of professionals.
In addition to the taught components, which will give an in-depth understanding of molecular pathology and associated disciplines (including genomics and bioinformatics), the full MSc course will also develop your experience of and skills in scientific investigation, analytical thought and scientific criticism.
Professional input into course content
This course has been designed to take into consideration the training requirements of biomedical scientists, clinical scientists and medical histopathologists. We have consulted with local Postgraduate Deaneries and associated professional bodies including the Institute of Biomedical Scientists (IBMS) and the Royal College of Pathologists to tailor the content.
The option to take the course over four years will particularly appeal to specialist trainee pathologists, who will be able to fit study around their clinical training. They can also use Year 4 to undertake the research project over three months on a full-time, salaried basis, as per RCPath regulations and Deanery funding.
Teaching is largely delivered through face-to-face, interactive sessions, consisting of some lecture material, with discussions and group work, and with a range of audio-visual stimuli including PowerPoint slides, images and videos.
All units are supported by the use of Blackboard (a virtual learning environment) on which staff post lecture slides, reading lists and other accompanying material.
Each unit on Blackboard also has its own discussion board, where you can interact with staff and other students on the course, for example, by posting and responding to questions, and making comments related to the course.
For students completing the full MSc, a significant amount of teaching and learning will take place through the dissertation research unit (60 credits or 30 credits), in which you will be expected to take a lead role in developing a research project with regular support, input, and mentorship from your project supervisor.
Formative assessments will be given throughout the taught component of the course and will take the form of MCQs, short answer questions, verbal presentations, data and method analysis exercises.
A range of summative assessments will be employed to assess your knowledge and understanding, and the development of your intellectual and transferable skills including:
The assessment methods employed by each unit will vary and will be tailored to match the material delivered and stated ILOs of that particular unit.
Your ability to gather information from a wide range of sources, evaluate and critically analyse information, make considered judgments about that information and synthesise material into logical and coherent pieces of work will all be assessed.
Examples of the marking proformas used in the assessment of verbal and written assignments will be provided in student handbooks and on Blackboard, the University's virtual learning environment.
As per the postgraduate taught degree regulations, students exiting with a postgraduate diploma (or postgraduate certificate) may be permitted to rescind this award and upgrade to a master's (or postgraduate diploma) by successfully completing the appropriate further component of the course, providing the following conditions are met:
Course content for Year 1
Optional units (max 1 per semester):
Course content for Year 2
Optional units (max 1 per semester):