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Masters Degrees (Pharmacogenomics)

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This Clinical Pharmacology degree programme offers focused training which integrates basic and clinical sciences, and equips students with the essential skills required to function effectively as a clinical pharmacologist in the 21st century. Read more

This Clinical Pharmacology degree programme offers focused training which integrates basic and clinical sciences, and equips students with the essential skills required to function effectively as a clinical pharmacologist in the 21st century. As a student on the MSc Clinical Pharmacology programme, you will acquire core skills, enabling an appreciation of how to apply clinical pharmacological, regulatory and ethical principles to the optimisation of therapeutic practice and clinical research. Crucially, in addition to a firm grasp of the principles of molecular pharmacology, you will also gain foundational knowledge in the emerging science of pharmacogenomics and personalised medicine.

Why this programme

  • This Clinical Pharmacology MSc is one of only a few UK postgraduate programmes that cover clinical pharmacology in sufficient detail to allow you to make an informed choice about pursuing clinical pharmacology as a career.
  • You will learn the basics of molecular genetics and population genetics as applied to pharmacogenetics and gene therapy.
  • You will have the opportunity to gain hands-on experience in molecular methods and analysis along with critical interpretation of genomic literature. This will enable you to analyse, synthesise and formulate an action plan for personalised patient care.
  • You will gain the knowledge and experience necessary to engage in and contribute to discussions about therapeutic issues in the commercial and academic research environments. As part of the MSc Clinical Pharmacology degree, you will undertake your own research project under expert supervision, which will allow you to consolidate your knowledge and apply the skills you have acquired.
  • At every stage of the MSc Clinical Pharmacology you will benefit from the close involvement of clinical academics and visiting lecturers from the pharmaceutical industry and national drug regulatory bodies: the programme is specifically designed to prepare graduate for future senior roles within the pharmaceutical medicine. Guest lecturers have recently included staff from Pfizer, Servier, Johnson & Johnson and the Scottish Medicines Consortium.

Programme structure

You will attend lectures, seminars and tutorials and take part in lab, project and team work.

Core courses

  • Principles of Pharmacology
  • Drug Disposition
  • Pharmaceutical Medicine
  • Topics in Therapeutics: General Topics and Cardiovascular Drugs
  • Topics in Therapeutics: Commonly Used Drugs
  • Medical Statistics 1
  • Medical Statistics 2
  • Pharmacogenomics & Molecular Medicine: Fundamentals of Molecular Medicine
  • Pharmacogenomics & Molecular Medicine: Applied Pharmacogenomics & Molecular Medicine

In addition you will undertake a dissertation/project.

Career prospects

Career opportunities include positions in academia, health care and the pharmaceutical industry; returning to more advanced positions within a previous clinical environment (eg pharmacicts, clinicians); and PhD study.



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Stratified Medicine holds huge potential in the timely development of new treatments for human disease. It is among the most important concepts to emerge in 21st century clinical science and will be a crucial component of the global drive to increase the efficacy, safety and cost effectiveness of new treatments. Read more

Stratified Medicine holds huge potential in the timely development of new treatments for human disease. It is among the most important concepts to emerge in 21st century clinical science and will be a crucial component of the global drive to increase the efficacy, safety and cost effectiveness of new treatments. This taught postgraduate Masters programme draws on the current and future needs of the Life Sciences sector, to create a highly skilled workforce. It harnesses Scotland’s strengths in Stratified Medicine, Clinical Trials, Bioinformatics and Pharmacogenomics to provide focused training which integrates basic and clinical sciences, and equips students with grounding in the essential skills required to design, execute and evaluate modern clinical interventions.

Why this programme

  • The programme will cover the principles which underpin the emerging science at the interface between genetics and pharmacology and the clinical evaluation of the resultant new medicines, taught by internationally recognised experts.
  • The aim of this programme is to train researchers who can break down the barriers that currently prevent discoveries at the bench from being translated into treatments at the bedside
  • The University of Glasgow has a global reputation in the field of clinical trials and stratified medicine. You will be taught by a multidisciplinary team of world leading scientists and clinicians within the College of Medical, Veterinary and Life Sciences.
  • Students will gain an understanding of statistical methods used to evaluate the efficacy and cost-effectiveness of new treatments.
  • Students on the programme will undergo theoretical and practical training in state-of-the-art research processes available to researchers in Glasgow, enabling an appreciation of how to apply novel stratified approaches, together with clinical pharmacological, regulatory and ethical principles to the optimisation of future clinical research and therapeutic practice.
  • We have excellent opportunities to engage with industrial and clinical scientists, with guest lecturers from the pharmaceutical industry, medical diagnostic laboratories and bioscience business which will help you understand the science, methodology and terminology used by scientists and clinicians from different disciplines. You will learn to communicate effectively in a multidisciplinary environment, critically evaluate a wide range of scientific data and research strategies and learn how to make a significant contribution to research and treatment in the 21st century.
  • Students will learn how all of the above techniques are applied by academic and industrial researchers in the development of new medicines.
  • Scholarships available

Programme structure

Students will undertake core courses which will account for 90 credits and a further 30 credits from options, which will enable students to personalise their degree to better align it with their future career aspirations. Students will also be offered a choice of project.

Core courses

  • Topics in Therapeutics: General Topics and Cardiovascular Disease
  • Pharmacogenomics and Molecular Medicine: Fundamentals of Molecular Medicine 
  • Medical Statistics 1
  • Evidence Based Research in Medicine 
  • Drug Disposition
  • Clinical Trials: Principles and Methods

Optional courses

  • Pharmacogenomics & Molecular Medicine: Applied Pharmacogenomics and Molecular Medicine
  • Topics in Therapeutics: Commonly Used Drugs
  • Pharmaceutical Medicine
  • Medical Statistics 2
  • Established and Novel Techniques in Cardiovascular & Medical Sciences Research

Project and assessment

The project will account for the remaining 60 credits. The programme will include an opportunity for all students to present the outcomes of their projects to an audience of other students and academics. Assessment will consist of submission of a dissertation and a viva examination.

Career prospects

Graduates of this programme will be competitive applicants for the positions in the commercial life sciences sector, or for PhD study in an academic or combined commercial/academic environment.



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Pharmacy at Sunderland is ranked sixth in the country, according to The Guardian University Guide 2013. Read more
Pharmacy at Sunderland is ranked sixth in the country, according to The Guardian University Guide 2013.

Course overview

Do you want to contribute to the discovery and development of drugs that could potentially improve the health and well-being of millions of people? The UK has long been a leader in this complex technical area, in which each new drug requires around $1 billion of development work.

Our research-led teaching and state-of-the-art facilities make the University of Sunderland one of the UK's top locations for pharmaceutical science. Our strong links with the pharmaceutical industry ensure a flow of guest speakers and good contacts for your chosen Masters project/dissertation. Previous projects have involved collaborations with companies such as AstraZeneca, Pfizer and Helena Biosciences.

The course covers advanced pharmaceutics, pharmaceutical analysis, drug design, pharmacology, proteomics and pharmacogenomics. You will also cover regulatory processes for medicines, in line with ICH guidelines. The course is a direct response to employers’ search for postgraduates who have a mix of theoretical and practical skills and who will push boundaries in drug development.

With a Masters course, it’s important to consider the relevance of the research interests of tutors who will supervise your dissertation. At Sunderland, our interests include pharmaceutical analysis, process chemistry, various drug discovery programmes, and drug delivery systems, including those for large biological pharmaceuticals. Our academic team have produced some ‘world-leading’ research, according to the latest Research Excellence Framework (2014).

Course content

The course mixes taught elements with self-directed research. The topic of the project / dissertation is negotiated to fit both your personal interests and the expertise of Sunderland's supportive tutors. Modules on this course include:
Core modules
-Essential Research and Study Skills (20 Credits)
-Fundamentals for Pharmaceutical Science (20 Credits)
-The Pharmaceutical R&D Cycle and its Regulation (20 Credits)

Choose four out of the five following modules
-Advanced Pharmacology (15 Credits)
-Pharmacogenomics and Proteomics (15 Credits)
-Advanced Pharmaceutical Analysis (15 Credits)
-Advanced Drug Design (15 Credits)
-Advanced Pharmaceutics (15 Credits)

Choose one Masters option
-Double Project (60 Credits)
Or
-Double Dissertation (60 Credits)
Or
-Single Project (30 Credits) and Single Dissertation (30 Credits)

Teaching and assessment

We use a wide variety of teaching and learning methods which include lectures, seminars, open learning, laboratory work and group work.

The Masters project may involve collaboration with a pharmaceutical company. Previous projects have involved collaborations with companies such as AstraZeneca, Pfizer and Helena Biosciences.

Compared to an undergraduate course, you will find that this Masters requires a higher level of independent working and problem solving. Assessment methods include laboratory reports, oral presentations, case studies, critical reviews, examinations and the Masters project.

Facilities & location

This course is based in the Sciences Complex at our City Campus, which boasts multi-disciplinary laboratories and cutting-edge equipment thanks to multi-million pound investments.

Facilities for Pharmaceutics
We have pharmaceutical-related equipment for wet granulation, spray drying, capsule filling, tablet making, mixing inhalation, film coating and freeze drying. As well as standard pharmacopoeial test methods, such as dissolution testing, friability and disintegration, we also offer highly sophisticated test methods. These include rheometry, thermal analysis (differential scanning calorimetry and hot stage microscopy), tests for powder flow, laser diffraction, photon correlation spectroscopy, image analysis and laser confocal microscopy.

Facilities for Medicinal Chemistry
Our state-of-the-art spectroscopic facility allows us to confirm the structures of new molecules that could be potential pharmaceutical products and to investigate the structures of potential medicinal substances that have been isolated from plants. We are equipped with Liquid Chromatography-Nuclear Magnetic Resonance and Mass Spectroscopy (LC-NMR/MS) platforms; this is an exceptional facility for a university. We also have low and high resolution mass spectrometry, nuclear magnetic resonance and elemental analysis equipment. Our facilities allow you to gain hands-on experience of a wide range of analytical techniques such as atomic absorption spectroscopy and infra-red spectroscopy, which are of great importance in determining both ionic/metal content of pharmaceuticals and simple chemical structures respectively. You will also gain experience of revolutionary protein and DNA separation techniques, as well as Ultra High Performance Liquid Chromatography (x8) and Gas Chromatography for separating all kinds of samples of pharmaceutical or biomedical interest.

Facilities for Pharmacology
Our highly technical apparatus will give you first-hand experience of the principles of drug action and the effects of drugs on pharmacological and cellular models. As a result, you gain a better understanding of the effects of drugs on specific receptors located throughout the human body and related physiological effects.

University Library Services
We’ve got thousands of books and e-books on pharmaceutical and biomedical science, with many more titles available through the inter-library loan service. We also subscribe to a comprehensive range of print and electronic journals so you can access the most reliable and up-to-date academic and industry articles. Some of the most important sources for your studies include:
-Embase, which is a complex database covering drug research, pharmacology, pharmaceutics, toxicology, clinical and experimental human medicine, health policy and management, public health, occupational health, environmental health, drug dependence and abuse, psychiatry, forensic medicine and biomedical engineering/instrumentation
-PsycINF, which includes information about the psychological aspects of medicine, psychiatry, nursing, sociology, pharmacology and physiology
-PubMed, which contains life science journals, online books and abstracts that cover fields such as medicine, nursing, dentistry, veterinary medicine and health care
-Science Direct, which offers more than 18,000 full-text journals published by Elsevier
-Web of Science, which covers a broad range of science areas

Learning Environment
Sunderland Pharmacy School has a rich heritage in scientific studies and our degree courses are extremely well respected in the industry. We are fully plugged into relevant medical and pharmaceutical industry bodies, with strong links and an exchange of ideas and people. Your Masters project may involve collaboration with a pharmaceutical company, including working at their sites.

Employment & careers

Graduates from this course can pursue a variety of careers in the following areas; Drug Design, Pharmaceutical Analysis and Research, Pre-clinical Research in Experimental and Biological Studies, Formulation and Product Development, Pharmacogenomics and Proteomics, Clinical Research, Product Registration, Licensing and Regulatory Affairs.

Previous Sunderland graduates have been employed in companies such as GSK, Eisai, Reckitt Benckiser, Merck, Sharp & Dohme and Norbrook Laboratories.

Some students may apply for a PhD programme or those who already hold a Pharmacy degree can pursue MSc/PG Pharmaceutical Sciences for the Overseas Pharmacist Assessment Programme (OSPAP) and go through one-year pre-registration training.

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Stratified Medicine holds huge potential in the timely development of new treatments for human disease. It is among the most important concepts to emerge in 21st century clinical science and will be a crucial component of the global drive to increase the efficacy, safety and cost effectiveness of new treatments. Read more

Stratified Medicine holds huge potential in the timely development of new treatments for human disease. It is among the most important concepts to emerge in 21st century clinical science and will be a crucial component of the global drive to increase the efficacy, safety and cost effectiveness of new treatments. This new taught postgraduate Masters programme draws on the current and future needs of the Life Sciences sector, to create a highly skilled workforce and is being developed in conjunction with the industrial partners of the Stratified Medicine Scotland Innovation Centre (SMS-IC). It harnesses Scotland’s strengths in Stratified Medicine, Clinical Trials, Bioinformatics and Pharmacogenomics to provide focused training which integrates basic and clinical sciences, and equips students with grounding in the essential skills required to design, execute and evaluate modern clinical interventions.

Why this programme

  • Students will be given the unique opportunity to undertake an industry placement as their main project. This fantastic opportunity will be offered by partner commercial organisations/companies and universities.
  • The programme will cover aspects of commercial innovation and entrepreneurial skills, together with the principles which underpin the emerging science at the interface between genetics and pharmacology.
  • Students on the programme will undergo theoretical and practical training in state-of-the-art research processes, enabling an appreciation of how to applynovel stratified approaches, together with clinical pharmacological, regulatory and ethical principles to the optimisation of future clinical research and therapeutic practice.
  • Students will also gain an understanding of statistical methods used to evaluate the efficacy and cost-effectiveness of new treatments, and direct experience of how all of these techniques are applied by academic and industrial researchers in the development of new medicines.
  • Following successful completion of the programme a joint master’s degree will be awarded.
  • The five stakeholder universities, Glasgow, Aberdeen, Strathclyde, Dundee and Edinburgh are internationally recognised as leaders in biomedical research, hosting highly collaborative and productive groups with the requisite expertise in pharmacology, clinical trial methodology, pharmacogenomics, and life sciences. This vibrant environment, coupled with Scotland’s tradition of excellence in clinical research and significant recent investment in the new science of Stratified Medicine make it the ideal place to acquire the transferrable skills required for a successful and fulfilling career in 21st century biomedicine.

Programme structure

This MSc degree is awarded jointly by the Universities of Glasgow, Aberdeen and Strathclyde. Courses included in this programme are delivered by these three institutions as well as the Universities of Dundee and Edinburgh. Students will be offered a choice of base institution, either Glasgow or Aberdeen. Each base campus has its own programme structure; however students from both campuses will study courses covering three themes totalling 120 credits. Sample course are included below. For the most up to date information on the courses available at each campus please contact 

Scientific basis of stratified medicine

  • Small molecule drug discovery
  • Biological drug discovery
  • Pharmacogenomics and molecular medicine.

Commercialisation of science

  • Introduction to bio-business
  • Advanced bio-business
  • New venture creation
  • Regulation and governance of new therapies

Application of research and evaluation of new technologies

  • Clinical trials: principles and methods
  • Applied statistics with routine health datasets
  • Spatial epidemiology
  • Applied health economics

Project and Assessment

The project will account for the remaining 60 credits. All projects will either have an industrial placement or a project which addresses an industrial need. The programme will include an opportunity for all students to present the outcomes of their projects to an audience of other students, academics and industry representatives. Assessment will consist of submission of a dissertation and presentation

Career prospects

Graduates will be able to pursue careers in a variety of academic and industrial areas including clinical research, preclinical lab-based research, business development with expert knowledge in life sciences and bioinformatics/biostatistics. 



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The course will provide a robust and wide-reaching education in fundamental and applied cancer biology, and focused training in laboratory research and associated methodology. Read more
The course will provide a robust and wide-reaching education in fundamental and applied cancer biology, and focused training in laboratory research and associated methodology.

Why study Cancer Biology at Dundee?

The MRes Cancer Biology is a research-centred taught Masters programme providing a focused training in molecular cancer research. It covers both the fundamental and translational science of carcinogenesis, cancer biology, diagnosis and therapy.

The programme delivers outstanding research-focused teaching from internationally-renowned scientists and clinicians.

Dundee University is internationally renowned for the quality of its cancer research and has over 50 cancer research groups: current funding for cancer research is about £40 million from research councils and charities. In 2009 the university became the first Scottish university to be awarded Cancer Centre status by the CRUK.

What's so good about studying Cancer Biology at Dundee?

The MRes Cancer Biology has been developed from the innovative collaboration between the College of Medicine, Dentistry and Nursing and the School of Life Sciences, and it complements the establishment of the Cancer Research UK (CRUK) Centre here in Dundee.

The Dundee Cancer Centre aims to enhance cancer research and apply discoveries to improve patient care. Key to this is training the next generation of cancer researchers.

Areas of particular strength at the University of Dundee are in surgical oncology for breast and colon cancer, radiation biology and clinical oncology, skin cancer and pharmacogenomics. Areas of strength in basic cancer biology are DNA replication, chromosome biology and the cell cycle, cell signalling and targets for drug discovery.

Teaching and Assessment

This course is taught by staff based in the College of Medicine, Dentistry and Nursing and the School of Life Sciences.

The MRes will be taught full-time over one year (September to August).

How you will be taught

The course will be taught through a combination of face-to-face lectures, tutorials, discussion group work and journal clubs, self-directed study and supervised laboratory research.

What you will study

The MRes degree course is taught full-time over three semesters.

The first semester provides in-depth teaching and directed study on the molecular biology of cancer, and covers:

Basic cell and molecular biology, and introduction to cancer biology
Cell proliferation, cell signalling and cancer
Cancer cell biology
Carcinogenesis, cancer treatment and prevention
Specific training in research methodology and critical analysis

Students will also be required to take part in a journal club to further develop their critical review skills.

In semesters two and three students will be individually guided to focus on a specific cancer research topic which will be the subject of a literature review and associated laboratory research project. The research project is based in laboratories with state-of-the-art facilities, and under the leadership of world-class researchers.

How you will be assessed

Exams on the taught element of the programme will be held at the end of semester one. Essays and assignments will also contribute to the final mark, and the dissertation will be assessed through the production of a thesis and a viva exam.

Places on the course are limited, so early applications are strongly encouraged.
Apply early to avoid disappointment.
Follow us on Twitter to keep up with news from the MRes Cancer Biology @Mrescancerbiol

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The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents. Read more

The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents.

About this degree

The programme provides a thorough grounding in modern approaches to the understanding of the genetics of disease alongside the cutting-edge research methods and techniques used to advance our understanding of development of disease. Core modules provide a broad coverage of the genetics of disease, research skills and social aspects, whilst specialised streams in Inherited Diseases, Pharmacogenetics and Computational Genomics, in which students can qualify, and the research project allow more in-depth analysis in areas of genetics.

Students undertake modules to the value of 180 credits.

The programme consists of four core modules (60 credits) and two specialist modules (30 credits) and a research project culminating in a dissertation (90 credits).

A Postgraduate Diploma consisting of six modules (four core modules in term one and two modules within the selected stream in term two) is offered, full-time nine months.

A Postgraduate Certificate consisting of four core modules in term one (60 credits) is offered, full-time three months.

Core modules

  • Advanced Human Genetics: Research Principles
  • Understanding Bioinformatics Resources and their Applications
  • Human Genetics: Core Skills
  • Basic Statistics for Medical Sciences

Specialist modules

In term two you will take specialist modules depending on the specialist stream you select: Inherited Disease (A); Pharmacogenetics (B); Computational Genomics (C). 

  • Applications in Human Genetics (A)
  • Either Genetics of Cardiovascular Disease or Genetics of Neurological Disease (A)
  • Clinical Applications of Pharmacogenetic Tests (B)
  • Anti-Cancer Personalised Medicine or Pharmacogenomics, adverse drug reactions and biomarkers (B)
  • Applications in Human Genetics (C)
  • Statistics for Interpreting Genetic Data (C)

Dissertation/report

Students undertake an original research project investigating topical questions in genetics and genetics of human disease which culminates in a dissertation of 12,000 to 14,000 words and an oral presentation.

Teaching and learning

Students develop their knowledge and understanding of genetics of human diseases through a combination of lectures, seminars, tutorials, presentations and journal clubs. Taught modules are assessed by unseen written examination and/or, written reports, oral presentations and coursework. The research project is assessed by the dissertation and oral presentation. 

Further information on modules and degree structure available on the UCL Genetics Institute website.

Further information on modules and degree structure is available on the department website: Genetics of Human Disease MSc

Careers

Advanced training in genetic techniques including bioinformatic and statistical approaches positions graduates well for PhD studentships in laboratories using genetic techniques to examine diseases such as heart disease, cancer and neurological disorders. Another large group will seek research jobs in the pharmaceutical industry, or jobs related to genetics in healthcare organisations.

Recent career destinations for this degree

  • Laboratory Specialist, King Abdullah Medical Complex
  • Non-Clinical Research Associate, University of Oxford
  • Trainee Geneticist, Oxford University Hospitals NHS Trust
  • PhD in Cardiovascular Science, UCL
  • Genomic Research Technician, Genome Centre

Employability

The MSc in Genetics of Human Disease facilitates acquisition of knowledge and skills relevant to a career in research in many different biomedical disciplines. About half of our graduates enter a research career by undertaking and completing PhDs and working as research associates/scientists in academia. Some of our graduates go on to jobs in the pharmaceutical industry, while others enter careers with clinical genetic diagnosis services, particularly in molecular genetics, in healthcare organisations and hospitals around the world. Those graduates with a prior medical training often utilise their new skills as clinical geneticists.

Careers data is taken from the ‘Destinations of Leavers from Higher Education’ survey undertaken by HESA looking at the destinations of UK and EU students in the 2013–2015 graduating cohorts six months after graduation.

Why study this degree at UCL?

UCL is in a unique position to offer both the basic science and application of modern genetics to improve human health. The programme is a cross-faculty initiative with teaching from across the School of Life and Medical Sciences (SLMS) at UCL.

Students will be based at the UCL Genetics Institute (UGI), a world-leading centre which develops and applies biostatistical and bioinformatic approaches to human and population genetics. Opportunities to conduct laboratory or computational-based research projects are available in the laboratories of world-leading geneticists affiliated to the UGI.

Research Excellence Framework (REF)

The Research Excellence Framework, or REF, is the system for assessing the quality of research in UK higher education institutions. The 2014 REF was carried out by the UK's higher education funding bodies, and the results used to allocate research funding from 2015/16.

The following REF score was awarded to the department: Division of Biosciences

82% rated 4* (‘world-leading’) or 3* (‘internationally excellent’)

Learn more about the scope of UCL's research, and browse case studies, on our Research Impact website.



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We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments. Read more

We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments.

As a student you will be registered with a University research institute, for many this is the Institute for Cellular Medicine (ICM). You will be supported in your studies through a structured programme of supervision and training via our Faculty of Medical Sciences Graduate School.

We undertake the following areas of research and offer MPhil, PhD and MD supervision in:

Applied immunobiology (including organ and haematogenous stem cell transplantation)

Newcastle hosts one of the most comprehensive organ transplant programmes in the world. This clinical expertise has developed in parallel with the applied immunobiology and transplantation research group. We are investigating aspects of the immunology of autoimmune diseases and cancer therapy, in addition to transplant rejection. We have themes to understand the interplay of the inflammatory and anti-inflammatory responses by a variety of pathways, and how these can be manipulated for therapeutic purposes. Further research theme focusses on primary immunodeficiency diseases.

Dermatology

There is strong emphasis on the integration of clinical investigation with basic science. Our research include:

  • cell signalling in normal and diseased skin including mechanotransduction and response to ultraviolet radiation
  • dermatopharmacology including mechanisms of psoriatic plaque resolution in response to therapy
  • stem cell biology and gene therapy
  • regulation of apoptosis/autophagy
  • non-melanoma skin cancer/melanoma biology and therapy.

We also research the effects of UVR on the skin including mitochondrial DNA damage as a UV biomarker.

Diabetes

This area emphasises on translational research, linking clinical- and laboratory-based science. Key research include:

  • mechanisms of insulin action and glucose homeostasis
  • insulin secretion and pancreatic beta-cell function
  • diabetic complications
  • stem cell therapies
  • genetics and epidemiology of diabetes.

Diagnostic and therapeutic technologies

Focus is on applied research and aims to underpin future clinical applications. Technology-oriented and demand-driven research is conducted which relates directly to health priority areas such as:

  • bacterial infection
  • chronic liver failure
  • cardiovascular and degenerative diseases.

This research is sustained through extensive internal and external collaborations with leading UK and European academic and industrial groups, and has the ultimate goal of deploying next-generation diagnostic and therapeutic systems in the hospital and health-care environment.

Kidney disease

There is a number of research programmes into the genetics, immunology and physiology of kidney disease and kidney transplantation. We maintain close links between basic scientists and clinicians with many translational programmes of work, from the laboratory to first-in-man and phase III clinical trials. Specific areas:

  • haemolytic uraemic syndrome
  • renal inflammation and fibrosis
  • the immunology of transplant rejection
  • tubular disease
  • cystic kidney disease.

The liver

We have particular interests in:

  • primary biliary cirrhosis (epidemiology, immunobiology and genetics)
  • alcoholic and non-alcoholic fatty liver disease
  • fibrosis
  • the genetics of other autoimmune and viral liver diseases

Magnetic Resonance (MR), spectroscopy and imaging in clinical research

Novel non-invasive methodologies using magnetic resonance are developed and applied to clinical research. Our research falls into two categories:

  • MR physics projects involve development and testing of new MR techniques that make quantitative measurements of physiological properties using a safe, repeatable MR scan.
  • Clinical research projects involve the application of these novel biomarkers to investigation of human health and disease.

Our studies cover a broad range of topics (including diabetes, dementia, neuroscience, hepatology, cardiovascular, neuromuscular disease, metabolism, and respiratory research projects), but have a common theme of MR technical development and its application to clinical research.

Musculoskeletal disease (including auto-immune arthritis)

We focus on connective tissue diseases in three, overlapping research programmes. These programmes aim to understand:

  • what causes the destruction of joints (cell signalling, injury and repair)
  • how cells in the joints respond when tissue is lost (cellular interactions)
  • whether we can alter the immune system and ‘switch off’ auto-immune disease (targeted therapies and diagnostics)

This research theme links with other local, national and international centres of excellence and has close integration of basic and clinical researchers and hosts the only immunotherapy centre in the UK.

Pharmacogenomics (including complex disease genetics)

Genetic approaches to the individualisation of drug therapy, including anticoagulants and anti-cancer drugs, and in the genetics of diverse non-Mendelian diseases, from diabetes to periodontal disease, are a focus. A wide range of knowledge and experience in both genetics and clinical sciences is utilised, with access to high-throughput genotyping platforms.

Reproductive and vascular biology

Our scientists and clinicians use in situ cellular technologies and large-scale gene expression profiling to study the normal and pathophysiological remodelling of vascular and uteroplacental tissues. Novel approaches to cellular interactions have been developed using a unique human tissue resource. Our research themes include:

  • the regulation of trophoblast and uNk cells
  • transcriptional and post-translational features of uterine function
  • cardiac and vascular remodelling in pregnancy

We also have preclinical molecular biology projects in breast cancer research.

Respiratory disease

We conduct a broad range of research activities into acute and chronic lung diseases. As well as scientific studies into disease mechanisms, there is particular interest in translational medicine approaches to lung disease, studying human lung tissue and cells to explore potential for new treatments. Our current areas of research include:

  • acute lung injury - lung infections
  • chronic obstructive pulmonary disease
  • fibrotic disease of the lung, both before and after lung transplantation.

Pharmacology, Toxicology and Therapeutics

Our research projects are concerned with the harmful effects of chemicals, including prescribed drugs, and finding ways to prevent and minimise these effects. We are attempting to measure the effects of fairly small amounts of chemicals, to provide ways of giving early warning of the start of harmful effects. We also study the adverse side-effects of medicines, including how conditions such as liver disease and heart disease can develop in people taking medicines for completely different medical conditions. Our current interests include: environmental chemicals and organophosphate pesticides, warfarin, psychiatric drugs and anti-cancer drugs.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.



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About the course. Lead academics. Dr Janine Kirby and Dr Dennis Wang. This course draws on expertise from three University faculties – Medicine, Dentistry and Health, Science, and Social Sciences – and the Sheffield Genetics Diagnostic Service (Sheffield Children’s Hospital NHS Foundation Trust). Read more

About the course

Lead academics: Dr Janine Kirby and Dr Dennis Wang

This course draws on expertise from three University faculties – Medicine, Dentistry and Health, Science, and Social Sciences – and the Sheffield Genetics Diagnostic Service (Sheffield Children’s Hospital NHS Foundation Trust). It’s aimed at students as well as professionals from healthcare and science backgrounds.

The syllabus was developed in partnership with Health Education England (HEE), in order to educate the next generation of healthcare professionals. This covers the scope and application of genomics in medicine and biomedical research as well as the ethical, social and legal issues relating to this field.

The course is taught by academics, scientists and clinicians. Learning methods range from lectures and tutorials to interaction with patients and online activities. You’ll get first-hand experience of hypothesis-driven research by carrying out your own project in Genomic Medicine.

How we teach

Classes are kept small (15–20 students) to make sure you get the best possible experience in laboratories and in clinical settings.

Our resources

We have a state-of-the-art biorepository and a £30m stem cell laboratory. The Sheffield Institute of Translational Neuroscience (SITraN) opened in November 2010. We also have microarray, genetics, histology, flow cytometry and high-throughput screening technology, and the latest equipment for bone and oncology research.

At our Clinical Research Facility, you’ll be able to conduct studies with adult patients and volunteers. The Sheffield Children’s Hospital houses a complementary facility for paediatric experimental medical research.

Hepatitis B policy

If your course involves a significant risk of exposure to human blood or other body fluids and tissue, you’ll need to complete a course of Hepatitis B immunisation before starting. We conform to national guidelines that are in place to protect patients, health care workers and students.

Core modules

  • Fundamentals in Human Genetics and Genomics
  • Omics Techniques and Application to Genomic Medicine
  • Genomics of Common and Rare Inherited Diseases
  • Molecular Pathology of Cancer
  • Introduction to Bioinformatics and Interpretation of Genomes
  • Genomics Research Project

Examples of optional modules

  • Advanced Bioinformatics and Genomic Data Analysis
  • Introduction to Counselling Skills used in Genomic Medicine
  • Application of Genomics in Infectious Disease
  • Pharmacogenomics and Stratified Health Care
  • Workplace-Based Genomic Medicine
  • Professional and Research Skills
  • Literature Review

Teaching and assessment

The MSc Genomic Medicine offers a wide range of delivery methods for providing theoretical knowledge, from lectures, laboratory sessions and tutorials to computer-based analysis workshops as well as the opportunity to gain input from internationally renowned experts in their fields. The inclusion of problem-based learning is embedded within the course and features in combinations of online and in-person interpretive class formats. Tutorials, seminars and individual meetings with staff provide opportunities for discussion and feedback. Each of the departments delivering the programme fosters an environment that provides many opportunities for individual and group learning.

PG Diploma, PG Certificate and Continuing Professional and Personal Development (CPPD) options are available as entry and exit options on both a full-time (over 1 year) or part-time basis (over 2 years).



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The UBC Department of Medical Genetics is an inspiring and productive community of scholars of genetics and genomics; an outstanding provider of knowledge… Read more

The UBC Department of Medical Genetics is an inspiring and productive community of scholars of genetics and genomics; an outstanding provider of knowledge, technical expertise, and compassionate care for our patients. The Department is composed of dozens of faculty members at the forefront of their fields who use cutting edge genetic, epigenetic, genomic, and bioinformatic methodologies to gain insight into diseases such as cancer, diabetes, obesity, neurodegenerative and neurological disorders, and other genetic diseases. Research is highly interactive and often involves local, national, and international collaborations which further enrich the research experience.

Individual labs conduct clinical and/or translational research and basic experimental research engaging a wide variety of approaches including the use of model organisms such as mice, flies (D. melanogaster), worms (C. elegans), and yeast (S. cerevisiae).

What makes the program unique?

The mission of the Department of Medical Genetics is to pursue basic and clinical research for diagnosis, prevention and treatment of genetic disease. Our goal is to be a world leader in the research, clinical practice and teaching of Genetic Medicine.

Research focus

Research in the Department of Medical Genetics covers the study of human genetics with areas of focus in mammalian development, regulation of gene expression, genetic diseases due to single gene or complex inheritance, birth defects, reproduction, cancer, immunology, genomics, bioinformatics, ethics and population health.

  • Research Areas of Expertise:
  • Cancer Genetics and Genomics;
  • Developmental Genetics & Birth Defects;
  • Epigenetics, Epigenomics & Chromosome Transmission;
  • Gene Expression, Genomics & Bioinformatics;
  • Genetic Epidemiology & Human Gene Mapping;
  • Neurogenetics & Immunogenetics;
  • Stem Cells & Gene Therapy;
  • Pharmacogenomics;
  • Proteomics; and
  • Clinical Genetics, Genetic Counselling and Ethics & Policy.

Program components

Medical Genetics Rotation Program: MSc and PhD applicants who have applied for the September-start, and who are highest ranked by the Medical Genetics Admissions Committee, will be offered the opportunity to join the Medical Genetics Rotation Program. The four top-ranked applicants offered these positions will also receive one-year Rotation Program Awards. Rotation Program students rotate through three different laboratories before choosing a final, thesis lab. Rotations are for nine-weeks each, from September to April. The Rotation Program is open to Canadians, Permanent Residents of Canada, and international applicants.

Career options

The MSc program in Medical Genetics is a research-based, thesis-based program which generally takes two - three years to complete. Graduates find employment in the public and private sector, and also pursue further studies in the field of Medical Genetics. Following is a brief sample of occupations that our graduates are pursuing:

Training:

  • Genetic Counselling
  • Medical Doctor
  • Clinical Genetics Technology

Industry / Clinical Careers:

  • Molecular Diagnostic Technologist
  • Research Associate
  • Data Management Coordinator
  • Research Program Manager
  • Online Marketing Coordinator
  • Scientific Sales Representative
  • Research and Development Scientist


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Genomic Medicine MSc is suitable for doctors, healthcare professionals and other students with an interest in Genomic Medicine. Overview. Read more

Genomic Medicine MSc is suitable for doctors, healthcare professionals and other students with an interest in Genomic Medicine.

Overview

This course follows a curriculum designed by Health Education England and is suitable for healthcare professionals and other students with an interest in Genomic Medicine. As a jointly taught programme delivered by St George’s, University of London and King's College London, students will benefit from the breadth of expertise provided by both institutions.

Students will learn how recent technological advances have transformed how genetic data is generated, analysed and presented and its relevance to a range of clinical scenarios. This will be a flexible programme, structured to provide options for PGCert and PgDip awards as well as the MSc.

Funding is available from Health Education England (HEE) for NHS employees wishing to apply for the programme (and individual modules). Prospective students wishing to apply for this funding should do so before applying for the course.

Highlights

- Taught jointly by St George’s and King's

- Institutions with world-class research, clinical and teaching expertise across the full spectrum of Genomic Medicine

- Integrated within the South London Genomic Medicine Centre

- Both campuses are co-located with leading teaching hospitals

- Institutional expertise in multi-professional education

- St George’s scored 92% overall student satisfaction in Postgraduate Taught Experience Survey 2014

- King’s clinical research ranked third in the UK, eleventh in the world

- St George’s clinical research ranked 4th for impact

- Both institutions are ranked among the top 200 universities in the world according to the recent Times Higher Education World University Rankings

Modules

This MSc award will consist of 8 core modules with a selection of optional modules.

Core modules:

- Fundamentals of human genetics and genomics (15 credits)

- Omics techniques and their application to genomic medicine (15 credits)

- Bioinformatics, interpretation, statistics and data quality assurance (15 credits)

- 60 Credit Research project or 30 Credit library-based dissertation

Core elective modules:

-Genomics of common and rare inherited diseases (15 credits)

-Application of genomics in infectious disease (15 credits)

-Pharmacogenomics and stratified healthcare (15 credits)

- Molecular pathology of cancer and application in diagnosis, screening and treatment (15 credits)

Optional modules

-Teaching, Learning, and Assessment in Healthcare and Science Education

- Counselling skills in genomics (15 credits)

- Cardiovascular genetics and genomics (15 credits)

-Ethical, legal and social issues in applied genomics (15 credits)

Careers

This course is designed for students who wish to acquire training in genomic technologies and the interpretation of their findings within a medical context. An MSc in Genomic Medicine will provide career opportunities for a range of professions from laboratory based researchers to diagnostic and healthcare professionals.

Studying

Teaching will be delivered at both St George’s and King's sites and will include a variety of methods including lectures, seminars, workshops and online formats.

Progress throughout the course will be assessed through a variety of methods, including MCQ, written and oral presentations.



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Our MSc in Genomic Medicine is accredited by Health Education England and designed to fulfil the aspirations of the . 100,000 Genome Project. Read more

Our MSc in Genomic Medicine is accredited by Health Education England and designed to fulfil the aspirations of the 100,000 Genome Project to create a world-class NHS workforce that understands and applies genomics for patient care.

This course is ideal whether you are a member of NHS staff or a science graduate. NHS professionals will learn how genomics impact on their area of clinical practice, while science graduates will receive training to help them gain employment in the healthcare sector (eg as a biomedical scientist or in genomic counselling) or pursue a PhD in the field.

We emphasise the practice of genomics and bioinformatics in the NHS and academia as a partnership between multiple stakeholders, including clinical, academic and industrial involvement.

As such, you will learn from clinical experts from the Manchester Centre for Genomic Medicine , The University of Manchester, Liverpool University, Public Health England, AstraZeneca and Qiagen.

Our MSc consists of taught units and a literature review or a bioinformatics-based project. You will be encouraged to use your intellectual curiosity, creativity and critical thinking in the practical application of genomics and bioinformatics.

MRes students will write a literature review and a research proposal (project 1) before going on to complete a six-month practical research project.

Teaching and learning

We take a student-focused and patient-centred approach to teaching and learning.

The course content is delivered using a combination of online and face-to-face methods including lectures, problem and evidence-based learning, workshops and collaborative learning.

The face-to-face elements are designed to help you develop the deeper contextualised specialist knowledge and critical evaluative skills necessary for a questioning and innovative approach to your learning and clinical practice.

You will learn from healthcare professionals and industry partners who are working at the forefront of practice and clinical research and can draw on their scholarship and expertise to help you build your knowledge.

If you choose to study the MRes qualification, the 25-week lab-based research project will provide excellent practical training in a number of research methods and techniques.

Course unit details

The MSc is divided into 15-credit core and optional units. Full-time students will normally do a 60-credit research project, and part-time students a 30-credit literature review.

Course collaborators

We collaborate with the following organisations to deliver this MSc:

What our students say

"So far, I have completed four modules on Bioinformatics, Human Genetics, Pharmacogenomics and Genetic Counselling. I can honestly say that I have thoroughly enjoyed each of these and they have opened my eyes to the potential transformation of healthcare in the NHS through genomic medicine."

Bradley Horn, Genetic Technologist

Disability support

Practical support and advice for current students and applicants is available from the Disability Advisory and Support Service .

CPD opportunities

Several units from this MSc can be taken as standalone courses for continuing professional development (CPD). Please visit the Genomic Medicine (CPD units) page for further information.

Career opportunities

Our course is designed to support and upskill healthcare professionals working in the NHS in areas where genomic medicine is becoming part of clinical practice.

Our science graduates have gone on to apply their new skills in service labs in their home countries, gained employment in the NHS, undertaken further study for genomic counselling, or have continued their research to pursue a PhD in the field.

Accrediting organisations

This course is accredited by Health Education England.



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Our flexible, blended MSc Molecular Pathology course will enable you to take advantage of growing opportunities within this field, which is critically important for translational medicine, both in cancer and non-cancer diseases. Read more

Our flexible, blended MSc Molecular Pathology course will enable you to take advantage of growing opportunities within this field, which is critically important for translational medicine, both in cancer and non-cancer diseases.

The number of academic pathologists trained in molecular pathology has steadily declined over the past 20 years. As such, it has been identified as an area requiring support and development by the Medical Research Council (MRC) and the Royal College of Pathologists, creating careers opportunities for students and professionals alike.

Our master's course is aimed at medical students, biomedical scientists, medical practitioners and trainee pathologists who want to learn more about molecular pathology. Trainee pathologists can take our course as part of an existing training programme.

You will benefit from a unique focus on the molecular analysis of tissue samples and take optional units in various areas of laboratory medicine and emerging diagnostic methods, such as proteomics and chemical pathology.

Students will also become part of Manchester's world leading precision medicine research community, learning practical skills that will be directly applicable to this emerging field.

In addition, you will benefit from our association with the network of MRC and Engineering and Physical Sciences Research Council funded Molecular Pathology nodes, which have been partly established to train more scientists to work in this field. This will enable you to connect with colleagues and related opportunities across the UK.

Aims

This course aims to provide you with a wide and detailed understanding of the various aspects of molecular pathology.

Provided as part of The University of Manchester MRC/EPSRC Molecular Pathology node (Manchester Molecular Pathology Innovation Centre), we recognise the need for providing more training in molecular pathology among histopathology trainees, clinical scientists and biomedical scientists.

As such, the course addresses a wide audience, and has a broad range of both core and non-core course units to facilitate the different learning and training needs of different groups of professionals.

In addition to the taught components, which will give an in-depth understanding of molecular pathology and associated disciplines (including genomics and bioinformatics), the full MSc course will also develop your experience of and skills in scientific investigation, analytical thought and scientific criticism.

Special features

Professional input into course content

This course has been designed to take into consideration the training requirements of biomedical scientists, clinical scientists and medical histopathologists. We have consulted with local Postgraduate Deaneries and associated professional bodies including the Institute of Biomedical Scientists (IBMS) and the Royal College of Pathologists to tailor the content.

Flexible learning

The option to take the course over four years will particularly appeal to specialist trainee pathologists, who will be able to fit study around their clinical training. They can also use Year 4 to undertake the research project over three months on a full-time, salaried basis, as per RCPath regulations and Deanery funding.

Teaching and learning

Teaching is largely delivered through face-to-face, interactive sessions, consisting of some lecture material, with discussions and group work, and with a range of audio-visual stimuli including PowerPoint slides, images and videos.

All units are supported by the use of Blackboard (a virtual learning environment) on which staff post lecture slides, reading lists and other accompanying material.

Each unit on Blackboard also has its own discussion board, where you can interact with staff and other students on the course, for example, by posting and responding to questions, and making comments related to the course.

For students completing the full MSc, a significant amount of teaching and learning will take place through the dissertation research unit (60 credits or 30 credits), in which you will be expected to take a lead role in developing a research project with regular support, input, and mentorship from your project supervisor.

Coursework and assessment

Formative assessments will be given throughout the taught component of the course and will take the form of MCQs, short answer questions, verbal presentations, data and method analysis exercises.

A range of summative assessments will be employed to assess your knowledge and understanding, and the development of your intellectual and transferable skills including:

  • verbal presentations;
  • written assignments;
  • data analysis and interpretation exercises;
  • analytical method analysis;
  • evaluation and formal unseen written examinations consisting of short answer questions and essays.

The assessment methods employed by each unit will vary and will be tailored to match the material delivered and stated ILOs of that particular unit.

Your ability to gather information from a wide range of sources, evaluate and critically analyse information, make considered judgments about that information and synthesise material into logical and coherent pieces of work will all be assessed. 

Examples of the marking proformas used in the assessment of verbal and written assignments will be provided in student handbooks and on Blackboard, the University's virtual learning environment.

As per the postgraduate taught degree regulations, students exiting with a postgraduate diploma (or postgraduate certificate) may be permitted to rescind this award and upgrade to a master's (or postgraduate diploma) by successfully completing the appropriate further component of the course, providing the following conditions are met:

  • the rescinding occurs within five years of your initial registration on the original course, subject to the course still being available;
  • an overall pass at the appropriate standard to assure admission to a master's course has been obtained for the postgraduate diploma (or postgraduate certificate), including any capped or compensated grades.

Course unit details

Course content for Year 1

Core units:

  • Professional and Research Skills (S1)
  • Molecular Pathology of Cancer (S2)
  • Omics Techniques and their Application to Genomic Medicine (S2)

Optional units (max 1 per semester):

  • Introduction to Clinical Biochemistry (S1)
  • Analytical Methods (S1)
  • Bioinformatics, Interpretation, Statistics and Data Quality Assurance (S2)
  • Diseases of Major Organs (S2)

Course content for Year 2

Core units:

  • Molecular Pathology of Non-malignant Disease (S1)
  • Diagnostic Histopathology and Molecular Diagnostic Pathology (S2)

Optional units (max 1 per semester):

  • Pharmacogenomics and Stratified Healthcare (S1)
  • Immunology and Infection (S1)
  • Diseases of Major Organs (S2)
  • Health Economics (S2)


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