The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents.
The programme provides a thorough grounding in modern approaches to the understanding of the genetics of disease alongside the cutting-edge research methods and techniques used to advance our understanding of development of disease. Core modules provide a broad coverage of the genetics of disease, research skills and social aspects, whilst specialised streams in Inherited Diseases, Pharmacogenetics and Computational Genomics, in which students can qualify, and the research project allow more in-depth analysis in areas of genetics.
Students undertake modules to the value of 180 credits.
The programme consists of four core modules (60 credits) and two specialist modules (30 credits) and a research project culminating in a dissertation (90 credits).
A Postgraduate Diploma consisting of six modules (four core modules in term one and two modules within the selected stream in term two) is offered, full-time nine months.
A Postgraduate Certificate consisting of four core modules in term one (60 credits) is offered, full-time three months.
In term two you will take specialist modules depending on the specialist stream you select: Inherited Disease (A); Pharmacogenetics (B); Computational Genomics (C).
Students undertake an original research project investigating topical questions in genetics and genetics of human disease which culminates in a dissertation of 12,000 to 14,000 words and an oral presentation.
Teaching and learning
Students develop their knowledge and understanding of genetics of human diseases through a combination of lectures, seminars, tutorials, presentations and journal clubs. Taught modules are assessed by unseen written examination and/or, written reports, oral presentations and coursework. The research project is assessed by the dissertation and oral presentation.
Further information on modules and degree structure available on the UCL Genetics Institute website.
Further information on modules and degree structure is available on the department website: Genetics of Human Disease MSc
Advanced training in genetic techniques including bioinformatic and statistical approaches positions graduates well for PhD studentships in laboratories using genetic techniques to examine diseases such as heart disease, cancer and neurological disorders. Another large group will seek research jobs in the pharmaceutical industry, or jobs related to genetics in healthcare organisations.
Recent career destinations for this degree
The MSc in Genetics of Human Disease facilitates acquisition of knowledge and skills relevant to a career in research in many different biomedical disciplines. About half of our graduates enter a research career by undertaking and completing PhDs and working as research associates/scientists in academia. Some of our graduates go on to jobs in the pharmaceutical industry, while others enter careers with clinical genetic diagnosis services, particularly in molecular genetics, in healthcare organisations and hospitals around the world. Those graduates with a prior medical training often utilise their new skills as clinical geneticists.
Careers data is taken from the ‘Destinations of Leavers from Higher Education’ survey undertaken by HESA looking at the destinations of UK and EU students in the 2013–2015 graduating cohorts six months after graduation.
UCL is in a unique position to offer both the basic science and application of modern genetics to improve human health. The programme is a cross-faculty initiative with teaching from across the School of Life and Medical Sciences (SLMS) at UCL.
Students will be based at the UCL Genetics Institute (UGI), a world-leading centre which develops and applies biostatistical and bioinformatic approaches to human and population genetics. Opportunities to conduct laboratory or computational-based research projects are available in the laboratories of world-leading geneticists affiliated to the UGI.
The Research Excellence Framework, or REF, is the system for assessing the quality of research in UK higher education institutions. The 2014 REF was carried out by the UK's higher education funding bodies, and the results used to allocate research funding from 2015/16.
The following REF score was awarded to the department: Division of Biosciences
82% rated 4* (‘world-leading’) or 3* (‘internationally excellent’)
Learn more about the scope of UCL's research, and browse case studies, on our Research Impact website.
Our Master of Research (MRes) in Translational Medicine will give you the research skills you need to use state-of-the-art biotechnologies to rapidly translate disease research into improved clinical healthcare.
Our understanding of the molecular basis of disease and drug mechanisms has improved dramatically in recent years, yet there is a distinct shortage of individuals able to apply this knowledge into effective clinical benefit. The core aim is to train the next generation of scientists able to 'fast-track' biological and scientific data into advanced therapies and diagnostics tools.
With advances in technology, graduates are faced with heightened expectations to conduct effective bioscience research. Employers demand skillsets with biological, medical, physical and computational characteristics, and our course is designed to provide this breadth of training.
You will learn omics skills and techniques such as genetics, genomics, transcriptomics, proteomics and metabolomics. Our training in metabolomic techniques is novel for a UK course, while our teaching on the integration of different omic platforms and data in a systems medicine strategy is also unique.
The MRes course consists of four taught units - which together make up the PGCert - plus an extended 35-week project that can be undertaken at the University, the Manchester Cancer Research Centre or a teaching hospital in Greater Manchester.
You can choose from a range of projects covering areas such as the use of gene expression profiling, proteomics, metabolomics, stem cell research, tissue culture or pharmacogenetics in the biology of cancer, cardiovascular disease, infectious diseases, stroke or diabetes.
Completing our course will open up a route into PhD research. You may also pursue a career in academia or the pharmaceutical or biotechnology industries, or as a clinical academic.
Extensive research experience
The 35-week research project for the MRes award offers the chance to conduct ambitious projects in areas such as cancer, cardiovascular disease, inflammation, mental health, infectious diseases, stroke or diabetes, using methods such as stem cell research, proteomics, metabolomics, tissue culture or pharmacogenetics.
Integrated focus on key topics
Our course has a strong and integrated focus on genetics, genomics, proteomics and metabolomics biotechnology and data interpretation, which are strengths within Manchester and are identified as core areas of bioscience growth.
Teaching comprises four taught units delivered using a variety of face-to-face, workshop and e-learning approaches and an extended 35-week research project for the MRes award.
Examples of research projects include the following.
Find out more by visiting the postgraduate teaching and learning page.
More than 50% of our graduates progress into PhD research at Manchester or other universities such as Cambridge, Imperial College London, Newcastle, Glasgow, Liverpool and Bristol.
Around 15% pursue a career in the pharmaceutical or biotechnology industry in the UK or abroad.
Approximately 25% are intercalating medics who complete their medical education. An estimated 10% pursue an undergraduate medical degree.
This Clinical Pharmacology degree programme offers focused training which integrates basic and clinical sciences, and equips students with the essential skills required to function effectively as a clinical pharmacologist in the 21st century. As a student on the MSc Clinical Pharmacology programme, you will acquire core skills, enabling an appreciation of how to apply clinical pharmacological, regulatory and ethical principles to the optimisation of therapeutic practice and clinical research. Crucially, in addition to a firm grasp of the principles of molecular pharmacology, you will also gain foundational knowledge in the emerging science of pharmacogenomics and personalised medicine.
You will attend lectures, seminars and tutorials and take part in lab, project and team work.
In addition you will undertake a dissertation/project.
Career opportunities include positions in academia, health care and the pharmaceutical industry; returning to more advanced positions within a previous clinical environment (eg pharmacicts, clinicians); and PhD study.
The Department of Oncology and the Department for Continuing Education’s CPD Centre offer a part-time MSc in Experimental and Translational Therapeutics that brings together some of Oxford's leading clinicians and scientists to deliver an advanced modular programme designed for those in full-time employment, both in the UK and overseas.
The Programme draws on the world-class research and teaching in experimental therapeutics at Oxford University and offers a unique opportunity to gain an understanding of the principles that underpin clinical research and to translate this into good clinical and research practice.
Visit the website https://www.conted.ox.ac.uk/about/msc-in-experimental-therapeutics
If your application is completed by this January deadline and you fulfil the eligibility criteria, you will be automatically considered for a graduate scholarship. For details see: http://www.ox.ac.uk/admissions/graduate/fees-and-funding/graduate-scholarships.
The MSc in Experimental and Translational Therapeutics is a part-time course consisting of six modules and a research project and dissertation. The programme is normally completed in two to three years. Students are full members of the University of Oxford and are matriculated as members of an Oxford college.
The modules in this programme can also be taken as individual short courses. It is possible to transfer credit from up to three previously completed modules into the MSc programme, if the time elapsed between commencement of the accredited module(s) and registration for the MSc is not more than two years.
- The Structure of Clinical Trials and Experimental Therapeutics
- Drug Development, Pharmacokinetics and Imaging
- Pharmacodynamics, Biomarkers and Personalised Therapy
- Adverse Drug Reactions, Drug Interactions, and Pharmacovigilance
- How to do Research on Therapeutic Interventions: Protocol Preparation
- Biological Therapeutics
The aim of the MSc programme is to provide students with the necessary training and practical experience to enable them to understand the principles that underpin clinical research, and to enable them to translate that understanding into good clinical and research practice.
By the end of the MSc programme, students should understand the following core principles:
- Development, marketing and regulations of drugs
- Pharmaceutical factors that affect drug therapy
- Pharmacokinetics, pharmacogenetics and pharmacodynamics
- Adverse drug reactions, drug interactions, and pharmacovigilance
- Designing phase I, II and III clinical trials for a range of novel therapeutic interventions (and imaging agents).
- Application of statistics to medicine
- Laboratory assays used to support trial end-points
- Use of non-invasive imaging in drug development
- Application of analytical techniques
By the end of the programme, students should be equipped to:
- demonstrate a knowledge of the principles, methods and techniques for solving clinical research problems and translate this into good clinical and research practice
- apply skills gained in techniques and practical experience from across the medical and biological sciences
- develop skills in managing research-based work in experimental therapeutics
- carry out an extended research project involving a literature review, problem specification and analysis in experimental therapeutics and write a short dissertation
Guidance from the UK Royal College of Physician's Faculty of Pharmaceutical Medicine
The Faculty have confirmed that if enrolled for Pharmaceutical Medicine Specialty Training (PMST), trainees may be able to use knowledge provided by Experimental Therapeutics modules to cover aspects of a module of the PMST curriculum. Trainees are advised to discuss this with their Educational Supervisor.
Experimental Therapeutics modules may also be used to provide those pursuing the Faculty's Diploma in Pharmaceutical Medicine (DPM) with the necessary knowledge required to cover the Diploma syllabus. Applicants for the DPM exam are advised to read the DPM syllabus and rules and regulations.
Members of the Faculty of Pharmaceutical Medicine who are registered in the Faculty's CPD scheme can count participation in Experimental Therapeutics modules towards their CPD record. Non-members may wish to obtain further advice about CPD credit from their Royal College or Faculty.
To complete the MSc, students need to:
Attend the six modules and complete an assessed written assignment for each module.
Complete a dissertation on a topic chosen in consultation with a supervisor and the Course Director.
The dissertation is founded on a research project that builds on material studied in the taught modules. The dissertation should normally not exceed 15,000 words.
The project will normally be supervised by an academic supervisor from the University of Oxford, and an employer-based mentor.
The following are topics of dissertations completed by previous students on the course:
- The outcomes of non-surgical management of tubal pregnancy; a 6 month study of the South East London population
- Analysis of the predictive and prognostic factors of outcome in a cohort of patients prospectively treated with perioperative chemotherapy for adenocarcinoma of the stomach or of the gastroesophageal junction
- Evolution of mineral and bone disorder in early Chronic Kidney Disease (CKD): the role of FGF23 and vitamin D
- Survey of patients' knowledge and perception of the adverse drug reporting scheme (yellow cards) in primary care
- The predictive role of ERCC1 status in oxaliplatin based Neoadjuvant for metastatic colorectal cancer (CRC) to the liver
- Endothelial Pathophysiology in Dengue - Dextran studies during acute infection
- Literature review of the use of thalidomide in cancer
- An investigation into the phenotypical and functional characteristics of mesenchymal stem cells for clinical application
- Identification of genetic variants that cause capecitabine and bevacizumab toxicity
- Bridging the evidence gap in geriatric medicines via modelling and simulations
The class-based modules will include a period of preparatory study, a week of intensive face-to-face lectures and tutorials, followed by a period for assignment work. Attendance at modules will be a requirement for study. Some non-classroom activities will be provided at laboratory facilities elsewhere in the University. The course will include taught material on research skills. A virtual learning environment (VLE) will provide between-module support.
The taught modules will include group work, discussions, guest lectures, and interaction and feedback with tutors and lecturers. Practical work aims to develop the students' knowledge and understanding of the subject.
Find out how to apply here - http://www.ox.ac.uk/admissions/graduate/applying-to-oxford
This course is for graduates of biological sciences who want to extend their studies into the professional field of dietetics. Dietetics is the management of diseases that are amenable to dietary intervention and the prevention of nutrition related disorders. A dietitian influences food selection and eating behaviour of an individual based on specific nutritional or food requirements.
With a clinical and health promotion focus, this course includes three blocks of integrated practice placements of 4, 12 and 12 weeks duration within a hospital and/or primary care setting.
The emphasis is on student-centred learning where your previous knowledge and skills are used to develop your new subject area. Learning activities include lectures, tutorials, workshops and practical classes and are guided using web-based supported materials.
You will also attend three practical placements to enable the integration of theoretical knowledge with practical experience. A variety of assessment methods are used across the course. Normally, there are 12 – 15 students on this course. This ensures that individuals receive excellent support and benefit from sharing their experiences with classmates.
Each module is equivalent to a notional 150 hours of work which is made up of attendance in class and independent work. The structure of each module is different with different attendance requirement for each timetabled module. Over an average semester the expectation is that during 14 weeks of teaching this will equate to approx. 40 hours per week of student effort (contact classes plus independent study time). Students normally complete the course via a full time route but part-time routes are available and can be discussed with the Programme Leader.
All placements are completed on a full-time basis, normally Monday – Friday, 9am – 5pm.
This course provides eligibility to apply for registration as a dietitian with the Health and Care Professions Council. It is also accredited by the British Dietetic Association.
15 credits: Food and Nutrition/ Principles of Nutrition Science/ Clinical Sciences/ Therapeutic Interventions/ Professional Studies/ Professional Practice/ Evaluation of Practice/ Pharmacology and Pharmacogenetics. You will also carry out practice placements, which you must pass but which do not carry any credit. If studying for an MSc, you will also complete a dissertation (60 credits).
Career prospects on completion of the course are varied. Most graduates normally choose to work within the NHS as dietitians. Others will work in health education, health promotion, general practice, private healthcare and government advisory posts. Opportunities also exist in the food and pharmaceutical industries in, for example: food labelling; nutrient profiling; product and recipe development; product evaluation and special diet foods. Some graduates may apply for the opportunity to study for a higher degree (MPhil or PhD).