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Masters Degrees (Pharmacodynamics)

We have 6 Masters Degrees (Pharmacodynamics)

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The Department of Oncology and the Department for Continuing Education’s CPD Centre offer a part-time MSc in Experimental Therapeutics that brings together some of Oxford's leading clinicians and scientists to deliver an advanced modular programme designed for those in full-time employment, both in the UK and overseas. Read more
The Department of Oncology and the Department for Continuing Education’s CPD Centre offer a part-time MSc in Experimental Therapeutics that brings together some of Oxford's leading clinicians and scientists to deliver an advanced modular programme designed for those in full-time employment, both in the UK and overseas.

The Programme draws on the world-class research and teaching in experimental therapeutics at Oxford University and offers a unique opportunity to gain an understanding of the principles that underpin clinical research and to translate this into good clinical and research practice.

Visit the website https://www.conted.ox.ac.uk/about/msc-in-experimental-therapeutics

The first deadline for applications is Friday 20 January 2017

If your application is completed by this January deadline and you fulfil the eligibility criteria, you will be automatically considered for a graduate scholarship. For details see: http://www.ox.ac.uk/admissions/graduate/fees-and-funding/graduate-scholarships.

Programme details

The MSc in Experimental Therapeutics is a part-time course consisting of six modules and a research project and dissertation. The programme is normally completed in two to three years. Students are full members of the University of Oxford and are matriculated as members of an Oxford college.

The modules in this programme can also be taken as individual short courses. It is possible to transfer credit from up to three previously completed modules into the MSc programme, if the time elapsed between commencement of the accredited module(s) and registration for the MSc is not more than two years.

Programme modules:

- The Structure of Clinical Trials and Experimental Therapeutics
- Drug Development, Pharmacokinetics and Imaging
- Pharmacodynamics, Biomarkers and Personalised Therapy
- Adverse Drug Reactions, Drug Interactions, and Pharmacovigilance
- How to do Research on Therapeutic Interventions: Protocol Preparation
- Biological Therapeutics

Course aims

The aim of the MSc programme is to provide students with the necessary training and practical experience to enable them to understand the principles that underpin clinical research, and to enable them to translate that understanding into good clinical and research practice.

By the end of the MSc programme, students should understand the following core principles:

- Development, marketing and regulations of drugs
- Pharmaceutical factors that affect drug therapy
- Pharmacokinetics, pharmacogenetics and pharmacodynamics
- Adverse drug reactions, drug interactions, and pharmacovigilance
- Designing phase I, II and III clinical trials for a range of novel therapeutic interventions (and imaging agents).
- Application of statistics to medicine
- Laboratory assays used to support trial end-points
- Use of non-invasive imaging in drug development
- Application of analytical techniques

By the end of the programme, students should be equipped to:

- demonstrate a knowledge of the principles, methods and techniques for solving clinical research problems and translate this into good clinical and research practice
- apply skills gained in techniques and practical experience from across the medical and biological sciences
- develop skills in managing research-based work in experimental therapeutics
- carry out an extended research project involving a literature review, problem specification and analysis in experimental therapeutics and write a short dissertation

Guidance from the UK Royal College of Physician's Faculty of Pharmaceutical Medicine

The Faculty have confirmed that if enrolled for Pharmaceutical Medicine Specialty Training (PMST), trainees may be able to use knowledge provided by Experimental Therapeutics modules to cover aspects of a module of the PMST curriculum. Trainees are advised to discuss this with their Educational Supervisor.

Experimental Therapeutics modules may also be used to provide those pursuing the Faculty's Diploma in Pharmaceutical Medicine (DPM) with the necessary knowledge required to cover the Diploma syllabus. Applicants for the DPM exam are advised to read the DPM syllabus and rules and regulations.

Members of the Faculty of Pharmaceutical Medicine who are registered in the Faculty's CPD scheme can count participation in Experimental Therapeutics modules towards their CPD record. Non-members may wish to obtain further advice about CPD credit from their Royal College or Faculty.

Assessment methods

To complete the MSc, students need to:

Attend the six modules and complete an assessed written assignment for each module.
Complete a dissertation on a topic chosen in consultation with a supervisor and the Course Director.

Dissertation:
The dissertation is founded on a research project that builds on material studied in the taught modules. The dissertation should normally not exceed 15,000 words.

The project will normally be supervised by an academic supervisor from the University of Oxford, and an employer-based mentor.

The following are topics of dissertations completed by previous students on the course:

- The outcomes of non-surgical management of tubal pregnancy; a 6 month study of the South East London population

- Analysis of the predictive and prognostic factors of outcome in a cohort of patients prospectively treated with perioperative chemotherapy for adenocarcinoma of the stomach or of the gastroesophageal junction

- Evolution of mineral and bone disorder in early Chronic Kidney Disease (CKD): the role of FGF23 and vitamin D

- Survey of patients' knowledge and perception of the adverse drug reporting scheme (yellow cards) in primary care

- The predictive role of ERCC1 status in oxaliplatin based Neoadjuvant for metastatic colorectal cancer (CRC) to the liver

- Endothelial Pathophysiology in Dengue - Dextran studies during acute infection

- Literature review of the use of thalidomide in cancer

- An investigation into the phenotypical and functional characteristics of mesenchymal stem cells for clinical application

- Identification of genetic variants that cause capecitabine and bevacizumab toxicity

- Bridging the evidence gap in geriatric medicines via modelling and simulations

Teaching methods

The class-based modules will include a period of preparatory study, a week of intensive face-to-face lectures and tutorials, followed by a period for assignment work. Attendance at modules will be a requirement for study. Some non-classroom activities will be provided at laboratory facilities elsewhere in the University. The course will include taught material on research skills. A virtual learning environment (VLE) will provide between-module support.

The taught modules will include group work, discussions, guest lectures, and interaction and feedback with tutors and lecturers. Practical work aims to develop the students' knowledge and understanding of the subject.

Find out how to apply here - http://www.ox.ac.uk/admissions/graduate/applying-to-oxford

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This course is specifically designed for nurses, midwives and allied health professionals who wish to undertake part-time study to prepare them to become a non-medical prescriber. Read more
This course is specifically designed for nurses, midwives and allied health professionals who wish to undertake part-time study to prepare them to become a non-medical prescriber. Nurses and midwives will be awarded the NMC recorded qualification (V300 Independent and Supplementary Prescribing) and allied health professionals will be awarded an annotation with the HPC as a Supplementary Prescriber.
The leading principle within the Non-Medical Prescribing course is to prepare you to deliver high quality care by equipping you to:
- Prescribe safely and effectively
- Use resources to your optimum effect for service users
- Improve well-being and reduce inequalities
- Provide evidence-based effective care
- Engage in policy making and actively participate in the multidisciplinary prescribing team

You can expect to study four modules:

•Pharmacology and therapeutics for prescribers (30 credits) will prepare students to understand and apply the principles of pharmacodynamics and pharmacokinetics directly related to prescribing practice. Practitioners will have the opportunity to critically analyse evidence based practice including risk assessment and management and to synthesise information relating to their own area of practice.
•Outline content includes: pharmacodynamics and pharmacokinetics; adverse drug reactions; numeracy; safe principles of prescribing; anatomy and physiology across the life span.
•Professional, legal and ethical issues for prescribers (15 credits) focuses on critically evaluating and synthesising ideas from the evidence in relation to the legal, ethical and professional issues implicit in non-medical prescribing decision making and consultations. Outline content includes: legislation and policies related to prescribing; accountability and responsibility for assessment, diagnosis and prescribing independently and within the multi-disciplinary team; patient safety in supervising, managing and evaluating prescribing decisions; prescribing effectively within a finite prescribing budget.
•Applied prescribing in the clinical context (15 credits) aims to critically evaluate the skills required for a comprehensive consultation for safe effective prescribing. In addition it is designed to promote synthesis of ideas influential in prescribing decision making. Outline content includes: appraisal of self and others regarding consultation skills in achieving medicines adherence; external pressures impacting on prescribing; different management options used to treat patients.
•Prescribing in practice for nurses and midwives / allied health professionals (0 credits) prepares students to prescribe from the British National Formulary as both independent and supplementary prescribers for nurses and midwives or as a supplementary prescriber for allied health professionals. Outline content includes: application of theory to practice; rationale for prescribing decisions; numeracy skills, writing prescriptions; prescribing in a range of scenarios. All practice experiences and practice outcomes for the whole course are based within this module.
Teaching and assessment
Our student-centred and enquiry-based approach to learning incorporates a wide variety of learning and teaching strategies, including; case studies, scenarios, small group work, action learning sets, workshops, pod casts, reflection, student presentations, supervised consultations with service users in practice and clinically focused tutorials. An essential part of the course will take place in practice settings under the guidance of a Designated Medical Practitioner, facilitated by your personal tutor. Students will also be supported by a designated qualified nurse prescriber, lead midwife for education, or supplementary prescriber for allied health, who will take up the role of preceptor at the end of the course.

Expertise
Our course team have a wide range of experience in non-medical prescribing provision. A key strength is that most are, or have been, independent and or supplementary prescribers from primary and secondary care in nursing, midwifery and pharmacy practice. The external examiner is also experienced in non-medical prescribing.

Graduate careers
A qualification in non-medical prescribing will be an essential aspect of your professional portfolio and will support your career progression through the advancement of your own practice in providing high quality patient care; thus enhancing your continued professional development needs.

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A master's in Clinical Pharmacology will enable you to gain the knowledge and skills to evaluate the safety of new medicinal products for human studies, write a clinical protocol, and obtain appropriate ethical and legal approval. Read more
A master's in Clinical Pharmacology will enable you to gain the knowledge and skills to evaluate the safety of new medicinal products for human studies, write a clinical protocol, and obtain appropriate ethical and legal approval. One of three modular programmes in Pharmaceutical Medicine designed for working physicians, clinical scientists and allied health professionals interested in the clinical development process.

Key benefits

- King's is ranked 4th in the world for Pharmacy & Pharmacology (QS World University Rankings by Subject 2016)

- Flexible programmes with a part-time option that allows you to fit the modules in with your work schedule.

- Teaching given by leading experts from the academic staff of King’s College London, from the biopharmaceutical sector and the regulatory authorities.

Visit the website: http://www.kcl.ac.uk/study/postgraduate/taught-courses/clinical-pharmacology-msc-pg-dip-pg-cert.aspx

Course detail

- Description -

Pharmaceutical Medicine is the medical scientific discipline concerned with the discovery, development, evaluation, registration, monitoring and medical aspects of the marketing of medicines for the benefit of patients and the health of the community.

In this rapidly expanding field of medicine there is a need for high quality education programmes that are compliant with the PharmaTrain initiative of the European Commission, but also with the Bologna process. The programmes at King’s will be the first in the UK that meet both of these requirements. This, plus the opportunity to study at a world class university makes King’s the ideal place at which to study for one of these MSc subjects.

Clinical Pharmacology is the study of how drugs influence human physiology and the way the body handles drugs. It is a vital part of the early clinical development of new medicines. It requires an understanding of preclinical science, ethical and legal requirements for clinical research programmes and how to design and interpret individual clinical trials. A well designed clinical pharmacology programme informs the final regulatory of a new medicine. Generating skilled clinical pharmacologists is therefore vital to ensure that new medicines are efficiently developed.

- Format and assessment -

Each taught module is delivered as a distinct intensive four or five day taught course, accompanied by distance learning and written assessments.

Core modules:

- ADME, Pharmacokinetics & Pharmacodynamics
- Advanced Clinical Pharmacology
- Clinical Drug Development
- Clinical Pharmacology Research Project
- Drug Development Pharmacology
- Exploratory Drug Development
- Practical Clinical Pharmacology

3 assignments plus 1 online multiple choice test for each module.

- Course purpose -

This programme is for those working in or seeking to work in the field of clinical drug development. It covers all aspects of the clinical development process through from the earliest studies to post marketing activities. It will enhance knowledge and skills in all aspects of clinical research, drug regulation and drug safety.

Career prospects

It is expected that students who complete this programme will be able to work in the clinical research arena at a higher level and this will open up job opportunities that might have previously been beyond their reach and enhance their value to their employers.

How to apply: http://www.kcl.ac.uk/study/postgraduate/apply/taught-courses.aspx

About Postgraduate Study at King’s College London:

To study for a postgraduate degree at King’s College London is to study at the city’s most central university and at one of the top 20 universities worldwide (2015/16 QS World Rankings). Graduates will benefit from close connections with the UK’s professional, political, legal, commercial, scientific and cultural life, while the excellent reputation of our MA and MRes programmes ensures our postgraduate alumni are highly sought after by some of the world’s most prestigious employers. We provide graduates with skills that are highly valued in business, government, academia and the professions.

Scholarships & Funding:

All current PGT offer-holders and new PGT applicants are welcome to apply for the scholarships. For more information and to learn how to apply visit: http://www.kcl.ac.uk/study/pg/funding/sources

Free language tuition with the Modern Language Centre:

If you are studying for any postgraduate taught degree at King’s you can take a module from a choice of over 25 languages without any additional cost. Visit: http://www.kcl.ac.uk/mlc

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This modular part-time programme is particularly suitable for academically gifted medical and dental trainees with the potential to be the independent researchers of the future. Read more
This modular part-time programme is particularly suitable for academically gifted medical and dental trainees with the potential to be the independent researchers of the future.

Applications for admisson in October 2016 are now open, the deadline to receive applications by is Friday 29 July 2016 (12 noon UK time).

Description

This progamme is designed to be taken by Academic Clinical Fellows alongside work commitments, the Health Research programme exists to enable students to:

- develop skills of research, design and data analysis in both qualitative and quantitative research

- critically evaluate health research

- identify, critically appraise and incorporate the results of medical and social science research into the day-to-day decision-making of clinical, scientific and administrative practice

- apply the principles of evidence-based practice in health care settings

- plan how to implement the findings of research to improve health care

- use theories and principles underpinning clinical research to inform their own research practice.

The programme is delivered through the Department for Continuing Education, with the expertise in curriculum design and teaching drawn from the Nuffield Department of Primary Care Health Sciences, the Centre for Evidence-Based Medicine, and the Oxford University Clinical Academic Graduate School.

Visit the website https://www.conted.ox.ac.uk/about/postgraduate-certificate-in-health-research

Programme details

The Postgraduate Certificate is normally completed between 1-2 years. It consists of three assessed taught modules and includes thorough introductions to the principles of evidence-based practice in health, and to study design and research methods.

Compulsory Modules

• The Practice of Evidence-Based Health Care
• Introduction to Study Design and Research Methods

The third module may be chosen from the following list:

- Clinical Trial Management
- Ethics for Biosciences
- Mixed Methods in Health Research
- Knowledge into Action
- Evidence-based Diagnosis and Screening
- Introduction to Statistics for Health Care Research
- Systematic Reviews
- Randomized Controlled Trials
- Qualitative Research Methods
- The Structure of Clinical Trials and Experimental Therapeutics
- How to do Research on Therapeutic Interventions: Protocol preparation
- Biological Therapeutics
- Pharmacodynamics, Biomarkers and Personalised Therapy
- Adverse drug reactions, drug interactions and Pharmacovigilance
- Drug development, Pharmacokinetics and Imaging

Course aims

At the end of the course students will be able to:

- demonstrate a knowledge of the principles, methods and techniques appropriate for solving evidence-based health care/health-research problems and be able to translate (through a critical comprehension of the relative advantages and disadvantages) that understanding into good clinical practice

- demonstrate a range of research skills enabling them to complete research successfully, either as part of a research team or as an individual

- acquire, interpret and analyse biological information with a critical understanding of the appropriate contexts for their use through the study of the existing primary literature in the field

- apply skills and expertise gained across the medical and biological sciences expected of professional researchers

Students will know and understand:

- health-care organizations, their management and the changing context in which they operate

- the ethical issues in health research and research governance

- methods to integrate and synthesise different sorts of information, from diverse sources, when making both individual patient and health-policy decisions in a wide range of situations

- the key issues for evidence-based practice in their own professional area or specialty

- how to work comfortably in situations of uncertainty and make sound judgements in the absence of definitive evidence

- research methods and concepts in the field of health and health care

All graduates of the Postgraduate Certificate in Health Research will be able to:

- understand the role of most commonly used methods appropriate for specifying problems through a critical comprehension of the relative advantages and disadvantages of these methods

- understand and express the main principles of some commonly applied techniques and methods

- explain the rationale for the selection of tools used in the analysis of phenomena.

Assessment methods

To complete the Postgraduate Certificate students must:

- Attend and complete the 2 compulsory modules and 1 option module.

Students will also be expected to complete three written assignments, usually of no more than 4000 words, one on each of the chosen modules above.

With the exception of the online modules, the EBHC modules are based on an eight week study cycle. Week One is a preparatory week where you may be required to undertake some pre-reading and to familiarise yourself with the Virtual Learning Environment. During Week Two you are required to attend the face to face teaching week in Oxford. This is followed by an additional six weeks where you are expected to participate in online activities and submit your assignment

Level and demands

Candidates will, in all but exceptional circumstances be admitted to the Postgraduate Certificate with optional progression on successful completion to the Diploma, provided that a candidate:

- has successfully completed the final year of the Bachelor of Medicine and Bachelor of Surgery or Bachelor of Dental Surgery or equivalent; or

- has an appropriate degree or equivalent professional qualification in a profession allied to medicine with post-qualification experience

Applicants will be expected to demonstrate an approach to their study which includes demonstrable skills of critical analysis, wide contextual knowledge and the ability to manage their own time.

Additionally candidates should:

- have a good working knowledge of email, internet, word processing and Windows applications (for communications with course members, course team and administration)

- show evidence of the ability to commit time to study and an employer's commitment to make time available to study, complete course work and attend course and University events and modules

Successful candidates will normally provide evidence of all of the following:

- A professional interest in Health Research, evidenced by prior experience, qualification and work

- Motivation and ability to complete the course

- A clear and well argued understanding of the benefits of the course to the candidate's current employment and future prospects

Find out how to apply here - http://www.ox.ac.uk/admissions/graduate/applying-to-oxford

Visit the Postgraduate Certificate in Health Research page on the University of Oxford website for more details!

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These are modular part-time programmes, particularly suitable for academically gifted medical and dental trainees with the potential to be the independent researchers of the future. Read more
These are modular part-time programmes, particularly suitable for academically gifted medical and dental trainees with the potential to be the independent researchers of the future.

It consists of two compulsory modules and four option modules selected from an extensive list of subjects. This provides the students with an opportunity to learn how the principles of health research can be translated into practical actions in selected areas.

The programmes are delivered through the Department for Continuing Education, with the expertise in curriculum design and teaching drawn from the Nuffield Department of Primary Care Health Sciences, the Centre for Evidence-Based Medicine, the Clinical Academic Graduate School and the Department of Statistics.

The two compulsory modules are:

- The Practice of Evidence-Based Health Care
- Introduction to Study Design and Research Methods

Three further modules may be chosen from List B
One further module either from List B or List C

List B:
- Clinical Trial Management
- Ethics for Biosciences
- Mixed Methods in Health Research
- Knowledge into Action
- Evidence-based Diagnosis and Screening
- Introduction to Statistics for Health Care Research
- Systematic Reviews
- Randomized Controlled Trials
- Qualitative Research Methods
- Essential Medical Statistics
- The Structure of Clinical Trials and Experimental Therapeutics
- How to do Research on Therapeutic Interventions: Protocol preparation
- Biological Therapeutics
- Pharmacodynamics, Biomarkers and Personalised Therapy
- Adverse drug reactions, drug interactions and Pharmacovigilance
- Drug development, Pharmacokinetics and Imaging

List C:
- Quality Improvement Science and Systems Analysis
- Human Factors, Teamwork and Communication
- Becoming a Medical Educator
- Teaching Evidence-Based Practice
- History and Philosophy of Evidence-Based Health Care

Course aims

This progamme is designed to enable students to:

- develop skills of research, design and data analysis in both qualitative and quantitative research

- critically evaluate health research

- identify, critically appraise and incorporate the results of medical and social science research into the day-to-day decision-making of clinical, scientific and administrative practice

- apply the principles of evidence-based practice in health care settings

- plan how to implement the findings of research to improve health care

- use theories and principles underpinning clinical research to inform their own research practice.

- demonstrate an ability to apply health research techniques appropriately for the solution of research questions;

- be able to apply health research solutions in a novel manner when analysing health research problems.

Find out how to apply here - http://www.ox.ac.uk/admissions/graduate/applying-to-oxford

Visit the Postgraduate Diploma in Health Research page on the University of Oxford website for more details!

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Our MSc Model-based Drug Development course provides the knowledge and skills for making evidence-based decisions at various stages of drug development. Read more
Our MSc Model-based Drug Development course provides the knowledge and skills for making evidence-based decisions at various stages of drug development.

It covers the scientific and regulatory aspects of evaluating a drug, with emphasis on the use of modelling and simulation methods. You will learn why these methods are so highly valued by industry and regulatory authorities as effective, cost-saving, decision-making tools. Learning is reinforced via hands-on application of the skills to real data.

The course has been developed with an emphasis on mechanistic approaches to assessing and predicting pharmacokinetics and pharmacodynamics (PKPD), such as physiologically-based pharmacokinetics (PBPK).

As this comes under the general umbrella of systems biology, you will be able to apply your knowledge of modelling and simulation in various areas of research within the pharmaceutical industry.

Full-time students benefit from immersion in the varied biomedical research environment at The University of Manchester, including interaction with research staff at the renowned Centre for Applied Pharmacokinetic Research.

Alternatively, part-time students already working in the pharmaceutical industry can take advantage of the flexible, distance learning mode of the course, which allows you to fit study around other commitments.

Aims

The aim of the course is to provide specialist knowledge and skills that are highly relevant for a career linked to drug development and pharmaceutical industry.

It is designed for science, engineering or mathematics graduates who want to acquire:
-Awareness of the commercial and regulatory factors in drug development
-Understanding of the physiological, chemical, and mathematical foundations used to define the safe and effective use of potential medicines
-Training in the use of mathematical modelling and simulation methods to guide drug development

The course aims to:
-Provide background information on the theory and methods for quantitative assessment of drug absorption, distribution and elimination
-Provide an understanding of the role of pharmacometrics in the process of drug development
-Provide background information on in vitro assays used to characterise ADME properties of new drug entities
-Indicate the mathematical framework that is capable of integrating in vitro information with knowledge of the human body to predict pharmacokinetics
-Provide familiarity and experience of using different software platforms related to pharmacometric data analysis including R, Phoenix, NONMEM, MATLAB, Simcyp, WinBUGS and MONOLIX
-Equip you to reflect upon influential research publications in the field, to critically assess recent published literature in a specific area
-Provide awareness of the elements of a convincing research proposal based on modelling and simulation
-Provide the opportunity to undertake a project and carry out original research

Teaching and learning

The course emphasises the development of problem-solving skills. A large portion of the learning involves structured problems requiring the you to apply theory and practical skills to solve typical problems that arise in drug development.

The following teaching and learning methods are used throughout the course:
-Taught lectures
-Hands-on workshops
-Self-directed learning to solve given problems
-Webinars and tutorials by leading scientists in industry/academia
-Supervised research
-Mentorship in solving problems and writing the research dissertation
-Independent study

Career opportunities

This course was originally developed for scientists working within the pharmaceutical industry who wished to qualify as modellers with hands-on experience. The qualification will enhance your abilities within your current role or provide you with skills to progress into new posts.

The course is also appropriate for science and engineering graduates who wish to enter the industry. The role of modelling and simulation or pharmacometrics is assuming greater and greater importance in the pharmaceutical industry. Pharmaceutical companies and government regulatory agencies are recognising its value in making best use of laboratory and clinical data, guiding and expediting development, saving time and costs and a range of well paid jobs exist in this area across the globe. Scientific and industry publications often discuss the current shortage and growing need for modellers.

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