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This programme gives you in-depth knowledge of the scientific basis of drug discovery and development, which has revolutionised the pharmaceutical industry in recent years. Read more
This programme gives you in-depth knowledge of the scientific basis of drug discovery and development, which has revolutionised the pharmaceutical industry in recent years. Our involvement with international drug companies has allowed us to keep our courses fully up-to-date. With our excellent facilities, emphasis on practical work, and teaching underpinned by the latest research, you will be qualified for research and development positions in pharmaceutical companies, as well as a wide range of other roles in industry.

About the course

The programme will have a heavy emphasis on practical work and will cover the following areas:
-Pharmacological and relevant physiological principles
-Molecular biology techniques in pharmacology
-The application of bioinformatics to drug discovery
-Quantitative aspects of pharmacology
-Case studies in drug discovery
-Molecular medicine
-Neuro-degenerative diseases
-Safety evaluationResearch project

You will undertake a practical project as part of your MSc enabling you to use our excellent facilities and to gain experience working alongside researchers in our Pharmacology Research Group. Current research projects include studies in:
-Gastrointestinal pharmacology, particularly with respect to diabetes
-Angiogenesis
-Cancer
-Cannabinoids as therapeutic agents
-Molecular pharmacology of vascular disease
-Modelling pharmacokinetics

Why choose this course?

-This is an intensive programme that will provide training in pharmacology, molecular biology and their application to drug discovery, using a problem based learning approach
-You will receive training in a range of pharmacological and molecular practical techniques as well as completing a research project
-Upon completion, you will be able to enter a successful career in the pharmaceutical industry or pursue further postgraduate research
-The School of Life and Medical Science will move into a brand new science building opening in September 2015 providing us with world class laboratories for our teaching and research. At a cost of £50M the new building provides spacious naturally lit laboratories and social spaces creating an environment that fosters multi-disciplinary learning and research

Careers

Graduates of the programme will be qualified for research and development positions in the pharmaceutical industries, to progress to a research degree or to consider regulatory, marketing or management roles in industry.

Teaching methods

Upon entering the programme, students are provided with introductory material to facilitate their transition to Master's level study. Cellular Molecular Biology is taught in parallel with Core Pharmacology, which both involve a high proportion of practical work. Students will experience a range of learning styles including conventional lectures, workshops and problem based learning. Teaching in Molecular Medicine and Pharmacovigilance & Drug Discovery Development uses case studies to foster skills such as working independently or as part of a team, demonstrating initiative and problem solving. You will also study a module in Biosciences Research Methods for Masters. All assessments are coursework only (including in-class tests), which are strategically phased throughout the course to provide regular feedback.

Structure

Modules
-Biosciences Research Methods for Masters
-Cellular Molecular Biology
-Core Pharmacology
-Drug Discovery Development and Pharmacovigilance
-Molecular Medicine
-Project-Mol Biology, Biotechnology, Pharmacology

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This programme will give you hands-on practical experience of both laboratory and bioinformatics techniques. You will also be trained in biotechnology research strategies. Read more
This programme will give you hands-on practical experience of both laboratory and bioinformatics techniques. You will also be trained in biotechnology research strategies. A strong practical foundation is provided in the first semester (Semester A) when you study two modules: 'Cellular Molecular Biology' and 'Core Genetics and Protein Biology'. These modules concentrate on the basic principles and the techniques used in modern molecular biology investigations, and on aspects of cellular molecular biology and development.

The second semester (Semester B) has a problem-based learning approach to the application of the knowledge you gained in Semester A. You will study two modules: 'Industrial Biotechnology' and 'Molecular Biotechnology'. These modules will give you an in depth understanding of the application of molecular biological approaches to the production of industrial and medicinal proteins. You will also learn how to apply and design industrial and environmental biotechnology processes, such as process kinetics and design, reactor design and oxygen transfer, sterilization kinetics and the application of biotechnology processes for the bioremediation of contaminated sites.

In the third semester (Semester C) you undertake a research project to develop your expertise further. The research project falls into different areas and may include aspects of fermentation biotechnology, genetic manipulation and protein engineering, bioinformatics, microbial physiology and environmental biotechnology.

Why choose this course?

-This course gives in-depth knowledge of biotechnology and molecular biology for biosciences or biological chemistry graduates
-It has a strong practical basis giving you training in biotechnology research strategies and hand-on experience of laboratory and bioinformatics techniques
-It equips you for research and development positions in the biotechnology and pharmaceutical industries, as well as a wide range of non-research roles in industry
-Biosciences research facilities cover fermentation biotechnology, high performance liquid chromatography, (HPLC), cell culture, molecular biology and pharmacology
-There are excellent facilities for chemical and biomedical analysis, genetics and cell biology studies and students have access to the latest equipment for chemical synthesis and purification, PCR, qPCR and 2D protein gel analysis systems for use during their final year projects
-The School of Life and Medical Science will move into a brand new science building opening in September 2015 providing us with world class laboratories for our teaching and research. At a cost of £50M the new building provides spacious naturally lit laboratories and social spaces creating an environment that fosters multi-disciplinary learning and research

Careers

On successful completion of the programme you will be well qualified for research and development positions in the biotechnology and pharmaceutical industries, to progress to a research degree or to consider non-research roles in industry such as management, manufacturing and marketing.

Teaching methods

The course consists of five modules including a research project:
-Cellular Molecular Biology
-Core Genetics and Protein Biology
-Industrial Biotechnology
-Molecular Biotechnology
-Biosciences Research Methods for Masters
-Research project

All modules are 100% assessed by coursework which includes in-course tests.

Structure

Core Modules
-Biosciences Research Methods for Masters
-Cellular Molecular Biology
-Core Genetics and Protein Biology
-Industrial Biotechnology
-Molecular Biotechnology
-Project-Mol Biology, Biotechnology, Pharmacology

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This interuniversity 'master after master' program (60 ECTS) is jointly organized by the Belgian Nuclear Higher Education Network (BNEN), a consortium of six Belgian universities. Read more

Organizing institutions

This interuniversity 'master after master' program (60 ECTS) is jointly organized by the Belgian Nuclear Higher Education Network (BNEN), a consortium of six Belgian universities: Vrije Universiteit Brussel, Katholieke Universiteit Leuven, Universiteit Gent, Université de Liège , Université Catholique de Louvain et Université Libre de Bruxelles and the Belgian Nuclear Research Centre (SCK-CEN). Students can enroll for this master program at each of the six partner universities. The program is built up of 31 ECTS of common compulsory courses, 9 ECTS of elective courses and a compulsory Master Thesis of 20 ECTS.

The primary objective of the programme is to educate young engineers in nuclear engineering and ts applications and to develop and maintain high-level nuclear competences in Belgium and abroad. BNEN catalyses networking between academia, research
centres, industry and other nuclear stakeholders. Courses are organised in English and in a modular way: teaching in blocks of one to three weeks for each course, allowing for optimal time management for professional students and facilitating registration for individual modules.
All courses take place at SCK•CEN, in Mol, Belgium. The lectures take place in a dedicated, brand-new classroom in the conference centre of SCK•CEN (Club-House), located in a wooded area and nearby the SCK•CEN restaurant and library services. SCK•CEN offers a variety of accommodation options: houses, villas, studios and dormitories. For more information visit: http://www.sckcen.be

About the programme

The one-year progamme was created in close collaboration with representatives of the utility companies and power plants and teaches students in all aspects of nuclear technology and its applications, creating nuclear engineering
experts in the broad sense. Exercises and hands-on sessions in the specialised laboratories of SCK•CEN complement the theoretical classes and strengthen the development of nuclear skills and attitudes in a research environment. Various technical visits
are organised to research and industrial nuclear facilities.
The programme can be divided into three core blocks:
ƒ- A set of introductory courses allowing refreshing or first contact with the basic notions of nuclear physics, material sciences and the
principles of energy production through use of nuclear phenomena.
ƒ- A core block of nuclear engineering applied to power generation and reactor use; theory of reactors and neutronics, thermal hydraulic problems encountered in reactor exploitation, the nuclear fuel cycle and the specific material corrosion problems.
-ƒ An applications block where safe and reliable operation of nuclear power plants and the legal and practical aspects of radiation protection and nuclear measurements are discussed.

Scholarships

BNEN grants are available for full-time students.

Curriculum

http://www.vub.ac.be/en/study/nuclear-engineering/programme

Nuclear energy: introduction 3 ECTS credits
Introduction to nuclear physics 3 ECTS
Nuclear materials I 3 ECTS
Nuclear fuel cycle and applied radiochemistry 3 ECTS
Nuclear materials II 3 ECTS
Nuclear reactor theory 8 ECTS
Nuclear thermal hydraulics 6 ECTS
Radiation protection and nuclear measurements 6 ECTS
Operation and control 3 ECTS
Reliability and safety 3 ECTS
Advanced courses 4 ECTS
Master thesis 15 ECTS
Total 60 ECTS

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A Masters’ studentship is available in the group of Dr. Martin Schröder in the School of Biological and Biomedical Sciences at Durham University to study stress signaling mechanisms originating from the endoplasmic reticulum. Read more
A Masters’ studentship is available in the group of Dr. Martin Schröder in the School of Biological and Biomedical Sciences at Durham University to study stress signaling mechanisms originating from the endoplasmic reticulum. Endoplasmic reticulum (ER) stress contributes to the development and progression of many diverse diseases affecting secretory tissues, such as diabetes and neurodegenerative diseases. The successful candidate will employ modern genetic and molecular techniques to understand the underlying cell biological mechanisms in endoplasmic reticulum stress signaling that maintain the homeostasis of the endoplasmic reticulum.

The MRes student will investigate control of ER stress signaling specificity by the dosage of ER stress. You will use a range of molecular biology and biochemical techniques to study (a) how the severity of ER stress alters the signaling outputs of the ER stress sensing protein kinase-endoribonuclease IRE1 or (b) how ER stress regulates transcriptional responses through the Rpd3-Sin3 histone/lysine deacetylase (see for example Schröder et al., 2000; Schröder et al., 2004). These techniques include protein expression and purification, immunoprecipitation, chromatin immunoprecipitation, cloning, transfection, and RNA analysis by real-time PCR or Northern blotting.

Overall, the studentship will provide interdisciplinary training in molecular biology, genetics, and cell biology.

References

M. Schröder, Cell. Mol. Life Sci. 65 (2008) 862-894: Endoplasmic reticulum stress responses.
M. Schröder, C. Y. Liu, R. Clark, and R. J. Kaufman, EMBO J. 23 (2004) 2281-2292: The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase.
M. Schröder, J. S. Chang, and R. J. Kaufman, Genes Dev. 14 (2000) 2962-2975: The unfolded protein response represses nitrogen-starvation induced developmental differentiation in yeast.

To apply

To apply: send a CV including the names of two references and a one page personal statement describing clearly your background, interest and experience in scientific research to . In your cover letter you should clearly identify the funding source to cover living expenses, tuition fees and bench fees. Further information can be found at https://www.dur.ac.uk/martin.schroeder or by contacting Dr. Martin Schroeder.

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