Our Microbiome in Health & Disease MSc provides students with a unique background in all aspects of both analysis of microbiome and determining the role of microbiome in pathology with experience in both computational and experimental techniques.
Designed and delivered by the newly established Centre for Host-Microbiome Interactions (CHMI) at King’s, the course brings together teaching on a varied course incorporating systems biology and bioinformatics with molecular biology, microbiology, immunology and physiology.
In the post-human genome project world, our health is dependent on more than our genes. High throughput sequencing reveals the amazing complexity and extent of the microbial communities that reside within or upon us. We are also beginning to understand just how dynamic the interactions between the host and members of communities are. Interactions are diverse, and variations observed between individuals depend on a multitude of microbial and host factors, including diet and inflammatory status. More importantly, it is becoming clear that different disease states are linked to significant changes in the make-up of these communities. Scientists who understand the computational analysis of the huge data sets for microbial communities, and who are also able to interpret findings in the context of human and microbial health, will be in demand across this emerging field in academia and in industry.
The MSc Microbiome in Health & Disease will provide you with a deep understanding of microbial communities and their diversity, and the impact of these communities on host health and disease. You will be exposed to the concepts and techniques involved in profiling and analysing large omics data sets associated with characterising and investigating microbial communities.
You will learn to analyse omics data sets, such as genome, transcriptome, metabolome and metagenome data, and how to integrate these data to develop a holistic understanding of the interactions between host and microbial communities in both health and disease states.
You will also learn how these skills apply in industry and have the opportunity to undertake research in collaboration with industrial partners. You will study the intersection between microbiome and engineering and learn how to identify and develop innovative products in different microbiome fields, applying learning from computational, multiomics analysis and basic biology, through advanced synthetic biology tools, and integrative analysis and modelling, to design new engineered therapeutic microbial communities and optimize their effectiveness in clinical, agricultural and environmental challenges.
You will also undertake a 10,000 word supervised dissertation on a subject within the field of microbiome in health and disease.
The course aims to develop students' knowledge of the microbial communities that reside within or upon us, and how they impact our health and disease processes.
It is designed for students who wish to improve their background knowledge and skills prior to applying for a PhD studentship, and also for students who wish to enhance their knowledge and skill set for analysing and interpreting the large, multiple omics data sets that are involved in microbiome research.
The MSc Microbiome in Health & Disease consists of 4 taught modules (two covering microbiology, microbial diversity and host-microbiome interactions, and two covering computational analysis of microbiome, and systems and synthetic biology), followed by a lab-based research project. The taught component will run from September until January, with the research component running from February until August.
Teaching comprises conventional lectures, tutorials and computational workshops, supported by example sessions, project work and independent learning via reading material and online courses. During the computational modules, you will be provided with data sets to analyse for written and oral projects.
After completing the taught component, you will undertake a lab-based research project for which you will provide a proposal and subsequent dissertation and presentation under the guidance of a supervisor.
The typical hours you will spend as you progress through your studies are as follows:
Lectures, seminars & feedback: 214 hours
Self-study: 1586 hours
Contact time is based on 24 academic weeks and self-study time is based on 31 academic weeks.
Typically, one credit equates to 10 hours of work.
You may typically expect assessment by a combination of coursework (76%) and examinations (24%).
The study time and assessment methods detailed above are typical and give you a good indication of what to expect. However, they may change if the course modules change.
This course provides comprehensive knowledge and practical training in the spread of microorganisms (predominantly bacterial and viral pathogens), disease causation and diagnosis and treatment of pathogens significant to public health. The increasing incidence of microbial infections worldwide is being compounded by the rapid evolution of drug-resistant variants and opportunistic infections by other organisms. The course content reflects the increasing importance of genomics and molecular techniques in both diagnostics and the study of pathogenesis.
In response to a high level of student interest in viral infections, the School has decided to offer the opportunity for students who focus on viruses in their module and project choices to be awarded a Master's degree in Medical Microbiology (Virology). This choice will depend on the module selection of the individual student in Terms 2 and 3 and choice of project.
Graduates from this course move into global health careers related to medical microbiology in research or medical establishments and the pharmaceutical industry.
The Bo Drasar Prize is awarded annually for outstanding performance by a Medical Microbiology student. This prize is named after Professor Bohumil Drasar, the founder of the MSc Medical Microbiology course.
The Tsiquaye Prize is awarded annually for the best virology-based project report.
- Full programme specification (pdf) (https://www.lshtm.ac.uk/files/mm_progspec.pdf)
- Intercalating this course (https://www.lshtm.ac.uk/study/courses/ways-study/intercalating-study-masters-degree)
Visit the website https://www.lshtm.ac.uk/study/masters/medical-microbiology
By the end of the course students should be able to:
- demonstrate advanced knowledge and understanding of the nature of viruses, bacteria, parasites and fungi and basic criteria used in the classification/taxonomy of these micro-organisms
- explain the modes of transmission and the growth cycles of pathogenic micro-organisms
- demonstrate knowledge and understanding of the mechanisms of microbial pathogenesis and the outcomes of infections
- distinguish between and critically assess the classical and modern approaches to the development of therapeutic agents and vaccines for the prevention of human microbial diseases
- demonstrate knowledge of the laboratory diagnosis of microbial diseases and practical skills
- carry out a range of advanced skills and laboratory techniques, including the purification of isolated microbial pathogens, study of microbial growth cycles and analyses of their proteins and nucleic acids for downstream applications
- demonstrate research skills
There is a one-week orientation period that includes an introduction to studying at the School, sessions on key computing and study skills and course-specific sessions, followed by two compulsory modules:
- Bacteriology & Virology
- Analysis & Design of Research Studies
Recommended module: Molecular Biology
Sessions on basic computing, molecular biology and statistics are run throughout the term for all students.
Terms 2 and 3:
Students take a total of five modules, one from each timetable slot (Slot 1, Slot 2 etc.). The list below shows recommended modules. There are other modules that can be taken only after consultation with the Course Director.
- Slot 1:
Molecular Biology & Recombinant DNA Techniques
- Slot 2:
Clinical Bacteriology 1
- Slot 3:
Advanced Training in Molecular Biology
- Slot 4:
Clincal Bacteriology 2
Molecular Biology Research Progress & Applications
- Slot 5:
Molecular Cell Biology & Infection
Further details for the course modules - https://www.lshtm.ac.uk/study/courses/masters-degrees/module-specifications
During the summer months (July - August), students complete a laboratory-based original research project on an aspect of a relevant organism, for submission by early September. Projects may take place within the School or with collaborating scientists in other colleges or institutes in the UK or overseas.
The majority of students who undertake projects abroad receive financial support for flights from the School's trust funds set up for this purpose
The Royal College of Pathologists accepts the course as part of the professional experience of both medical and non-medical candidates applying for membership. The course places particular emphasis on practical aspects of the subjects most relevant to current clinical laboratory practice and research.
Find out how to apply here - http://www.lshtm.ac.uk/study/masters/msmm.html#sixth
Why are microbes the most important group of organisms on our planet? How is knowledge of microbiology applied in medicine and industry, or in food production? What research techniques are used to study viruses, bacteria and other microbes? These are important questions, and you can find answers to these and many others in the study of Microbiology and microbial biotechnology.
Upon completing your degree, you will:
Further information about the studies on the Master's programme website.
The key contents of the study programme in Microbiology and microbial biotechnology are:
Our MRes Infection Biology programme will equip you with the knowledge and skills required to join the global fight against infectious diseases which threaten humanity.
Infectious disease remains a major cause of human death but the efficacy of antimicrobial interventions continues to decline. The discovery of novel preventative and therapeutic interventions now critically dependent upon a detailed mechanistic understanding of disease processes, their impact upon human pathobiology and the feasibility of therapeutically targeting such mechanisms.
With a view to training a generation of infection biologists equipped with the skills to tackle this global challenge, the MRes in Infection Biology provides outstanding academic and research training in the molecular and cellular basis of host-microbe interactions in health and disease.
You will learn directly from internationally recognised scientists through joint research, thereby securing a sustained interaction with expert mentors for the duration of the course.
The course provides research training in fundamental aspects of infectious diseases, microbial pathogenesis, host interactions, antimicrobial immunity, and antimicrobial therapy. For the talented student this course provides an excellent training prior to registration for a PhD.
This course will equip you with:
This course aims to:
Unique in New Zealand
The breadth and depth of Massey University’s postgraduate microbiology programme is unique in New Zealand.
Find out more about the Master of Science parent structure.
The Massey University Master of Science (Microbiology) is a multi-disciplinary postgraduate qualification that will give you the research skills to move up the hierarchy of your career, or move onto more in-depth research.
You will learn from world-leading specialists in microbiology and related areas like biochemistry, genetics, biotechnology, food science, plant pathology, immunology and epidemiology.
At Massey we use a diverse range of molecular, cellular, plant and animal model tools to investigate the molecular biology of diseases. We also use metagenomics and other advanced genomic technologies to study microbial communities in the environment, including those that may be health threat if found in food or medical environments.
Our biomedical interests are diverse. We research the mechanisms of neurological, skeletal and muscular disorders, infectious microbial diseases and cancer.
Facilities available to you include our microscopy and imaging centre, genomics and dna sequencing facility, protein analysis suite (mass spectroscopy, x-ray crystallography, nmr), bioreactors and fermentation facilities.
Microbiology is an essential science that helps us understand the microbes in the environment, including those that dwell in the soil, air and water, in our food and inside people, animals and plants.
Understanding microbiology can:
You will gain the advantage of learning in a multi-disciplinary environment. Massey has world-leading expertise in many areas of science, especially veterinary, animal, health and environmental science. You can take advantage of this for your learning and research to look at microbiological sub-disciplines, such as environment/ecology, food and biotechnology.
During your study you will gain a contemporary, relevant view of microbiology which is in line with topical research and developments in the area. You will be exposed to the latest discoveries and research.
There is a well-established community of fundamental scientists and students involved in a broad range of microbiological and microbiology-inspired research at Massey. We work together to share discoveries and research and provide peer support.
Postgraduate study is hard work but hugely rewarding and empowering. The workload of the Master of Science (Microbiology) replicates the high-pressure environment of senior workplace roles.
Postgraduate study is not just ‘more of the same’ as undergraduate study. Our experts are there to guide but if you have come from undergraduate study, you will find that postgraduate study demands more in-depth and independent study. It takes you to a new level in knowledge and expertise especially in planning and undertaking research.
This MRes Molecular Microbiology course will provide you with a strong grounding in microbial genetics and molecular biology, through the exploration of microbial structure, physiology, and behaviour at the molecular level. The course includes optional modules for you to select depending upon your aspirations and interests.
The MRes courses are divided into a taught element (60 credit points) and a laboratory-based research project (120 credit points). You will complete the extended research project in one of our highly rated research teams.
This exciting MSc Molecular Microbiology course is designed to provide you with a multidisciplinary approach to the study of the molecular biology of micro-organisms. You'll study the key concepts associated with molecular microbiology and use these when considering their role in health, disease and in the natural environment.
Practical work forms a large proportion of your learning to ensure that you have extensive skills for employment or research and there is an emphasis on developing knowledge and understanding such that you acquire the skills, qualities and attributes expected by employers or for postgraduate research.
The MSc is divided into 60 credit point taught modules and the research project is worth 60 credit points.
Visit us on campus throughout the year, find and register for our next open event on http://www.ntu.ac.uk/pgevents.
Radboud University’s Master’s specialisation in Microbiology deals with the interface between fundamental biological and medical sciences. It focuses on molecular, medical and environmental microbiology to improve our health and environment and provides in-depth insight into present-day microbial research in general and clinical microbiology.
The major topics of the Microbiology specialisation are:
Microorganisms can be used to break down environmental pollutants and toxic chemicals. Therefore microbiology has the potential to replace common energy-intensive chemical processes with more sustainable solutions. Radboud University collaborates closely with environmental scientists and industrial partners to create energy-efficient and environmentally friendly solutions for societal waste problems.
Unfortunately some microorganisms make us ill. A better understanding of battle between our immune system and these microorganisms will lead to the development of improved vaccines.
The genome of a microorganism is a key factor in research, because it determines how the organisms interact with the host cell and how they cause diseases. Molecular Microbiology acts on the interface between microbiology, molecular biology and genetics and is fundamental for the development of novel antibiotics and improvement of vaccines against microorganisms.
The department of Microbiology at Radboud University has been bestowed with the most prestigious science prizes, including two ERC Advanced Grants, a Spinoza Prize, and two Gravitation Grants. Additionally, many of out students have been awarded prizes for best thesis, poster and paper. The department works at the forefront of environmental microbiology and is specialised in the discovery of ‘impossible’, new anaerobic micro-organisms. The laboratory is equipped with state-of-the-art bioreactors, electron microscopy, GC-MS, metagenomics, and metaproteomics facilities to grow and study micro-organisms that contribute to a better environment by consuming greenhouse gasses and nitrogenous pollutants.
- Research themes
The Master's specialisation Microbiology is mainly focused on research. You can choose one of the following themes as the subject of your research internship:
- Environmental Microbiology & Biotechnology
For students who are intrigued by questions like: How does life without oxygen work? How do global biogeochemical (nutrient) cycles govern the functioning of the Earth? Can we use microorganisms to create a more sustainable wastewater industry? How do microorganisms break down environmental pollutants and toxic chemicals?
You will do research at the interface between Microbiology, environmental sciences and biochemistry. The research questions cover several levels, from gaining fundamental understanding of energy metabolism of bacteria to their applications in wastewater treatment.
Societal relevance: Microbiology has the potential to replace common energy-intensive chemical processes by more sustainable solutions. Radboud University collaborates closely with environmental scientists, animal ecologists and industrial partners to create energy-efficient and environmentally friendly solutions for societal waste problems.
For students who are intrigued by questions like: Why do some bacteria make us ill whereas others do not? How do bacteria outsmart our immune system? What are the mechanisms of human defence against microorganisms?
You will do research at the interface between Microbiology, Immunology and Cell Biology, and can, for example, work on how microorganisms are recognised by the host defence system
Societal relevance: A better understanding of host defence will lead to the development of improved vaccines against microorganisms.
- Molecular Microbiology
For students who are intrigued by questions like: How are microorganisms able to persist inside the human body and how do they cause diseases? What does gene regulation tell us about their pathogenic capabilities? Can microbial genomes help us determine how microorganisms interact with human host cells?
You will do research at the interface between Microbiology, molecular biology and genetics, and can, for example, work on functional gene analyses by mutagenesis studies and on the interaction between epithelial cells and pathogenic bacteria.
Societal relevance: Understanding host-pathogen interactions is fundamental for the development of novel antibiotics and improvement of vaccines. Radboudumc collaborates with public health institutes – such as the RIVM (National Institute of Public Health) – and with industrial partners.
- Personal tutor
Our top scientists are looking forward to guiding you during a challenging and inspiring scientific journey. This programme offers you many opportunities to follow your own interests under the excellent supervision of a personal tutor. This allows you to specialise in a field of personal interest.
- The Nijmegen approach
The first thing you will notice as you enter our Faculty of Science is the open atmosphere. This is reflected by the light and transparent building and the open minded spirit of the people working, exploring and studying there. It is no wonder students from all over the world have been attracted to Nijmegen. You study in small groups, with direct and open contact with members of the staff. In addition, Nijmegen has excellent student facilities, such as high-tech laboratories, libraries and study ‘landscapes'.
Studying by the ‘Nijmegen approach' is a way of living. We will equip you with tools which are valuable for the rest of your life. You will be challenged to become aware of your intrinsic motivation. In other words, what is your passion in life? With this question in mind we will guide you to translate your passion into a personalised Master's in Biology.
See the website http://www.ru.nl/masters/microbiology