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Masters Degrees (Metabolic Diseases)

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Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research. Read more

Understanding the molecular basis of disease

Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research.

Only by dissecting the molecular mechanisms that trigger and advance diseases and dysfunctions can we design effective treatments and medicines. The Research Master's in Molecular Mechanisms of Disease (MMD) offers you an intensive two-year programme that provides you with in-depth knowledge and research experience of disease-related molecular mechanisms. In addition, you will acquire skills such as academic writing and presentation skills and learn how to successfully apply for grants and market yourself.

Passion for molecular biomedical research

As an MMD student you will be part of the unique research community that is found within the Radboud Institute for Molecular Life Sciences (RIMLS). Like you, RIMLS researchers have a strong passion for research. They will assist you throughout the programme with guidance and expertise, supporting you in acquiring knowledge and developing excellent research skills. The RIMLS is one of the research institutes of the Radboud university medical center, so their research is closely linked to the clinic and thus aimed at translating results into treatments for patients. Examples include the translation of insights into the biology of antigen-presenting cells into new immunological cancer therapies and understanding the mutations underlying blindness into the development of gene therapies for patients with inherited blindness.

See the website http://www.ru.nl/masters/mmd

Why study Molecular Mechanisms of Disease at Radboud University?

- You will follow a broad biomedical programme that allows you to specialise in your specific field-of-interest.
- You will have intense daily contact with established researchers.
- You will participate in group-oriented education and be part of a small group of highly motivated national and international students.
- A personal mentor will help you to reflect on your study programme and career perspective.
- You will do two 6-months research internships one of which will be abroad.
- There is a 92% pass rate of MMD students within the two years.
- International MMD students can apply for scholarships from the Radboudumc Study Fund.

Career prospects

There is considerable demand for experts in the molecular biomedical sciences as well as in their application to the development of treatments for diseases such as cancer, autoimmune and inflammatory disorders, and metabolic diseases.

Graduates in MMD are equipped with cutting-edge knowledge of multidisciplinary research in the mechanisms of disease and in state-of-the-art diagnostic methods and technologies. During the programme, you will develop a highly critical, independent approach to problem-solving. You will also acquire the basic management skills needed to lead R&D projects in the biotechnology and pharmaceutical industries.

Most of our graduates will enter an international PhD programme to continue with research in academia or industry.

PhD opportunities

The MSc Molecular Mechanisms of Disease aims to provide all skills and knowledge necessary to rapidly enter an international PhD programme. In the Netherlands and many places in Europe, it is impossible to start a PhD programme directly after obtaining a Bachelor's degree. This research Master’s programme seriously increases your chances for obtaining an excellent PhD training position by giving you a mature perspective and a broad range of experimental approaches. In fact, over 90% of our graduates has started a (funded) PhD project.

The Radboud Institute for Molecular Life Sciences (RIMLS) recruits about fifty PhD students a year. MMD graduates are excellent candidates for these positions. Furthermore, the Radboud university medical centre offers the opportunity for its research-oriented Master's students to write their own research project. The best candidates are awarded a fully funded four-year PhD studentship at the department of their choice.

Our approach to this field

The molecular regulation of cellular processes is crucial for human development, and maintenance of health throughout life. It's evident that cellular malfunction is the cause of common multi-factorial diseases such as diabetes, immune and inflammatory disorders, renal disease, cardiovascular, metabolic and neurodegenerative diseases as well as obesity and cancer.

The Radboud Institute for Molecular Life Sciences (RIMLS) Graduate School plays a key role in developing new therapies for the fight against such diseases. RIMLS aims to improve diagnostics and develop new treatments by generating basic knowledge in the molecular biomedical life sciences and translating it into clinical application and experimental research in patients.

The RIMLS – which is part of Radboud university medical center – offers an exclusive Master's programme in Molecular Mechanisms of Disease. Top researchers and clinicians teach the programme.

Key themes

The MMD programme is organised along three major educational themes which reflect the main research areas present in the RIMLS and which each include both a fundamental and a disease-related aspect:
- Theme 1 Infection, Immunity and Regenerative Medicine / Immunity-related Disorders and Immunotherapy
- Theme 2 Metabolism, Transport and Motion / Metabolic Disorders
- Theme 3 Cell Growth and Differentiation / Developmental Disorders and Malignancies

See the website http://www.ru.nl/masters/mmd

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The Clore Laboratory is an internationally recognised centre for integrated research into diabetes, obesity and metabolic diseases. Read more
The Clore Laboratory is an internationally recognised centre for integrated research into diabetes, obesity and metabolic diseases.

Established in 1986, it currently has a staff 15 of whom five are postdoctoral research scientists. Currently, there are three DPhil students. Students benefit from the holistic nature of the research, which ranges from investigations at the molecular and cellular level through to whole-body physiology, including the role of dietary interaction with the genetic background in producing disease.

The Clore Laboratory was purpose-built for metabolic research and has excellent facilities for molecular and cell biology, as well as biochemistry, physiology and pharmacology. The range of scientific disciplines among the researchers provides an excellent training ground in research methodologies.

In circumstances where it is not possible for students to undertake residency in Buckingham but have full-time access to laboratory facilities, it may be possible to register for an MPhil/DPhil degree, subject to the suitability of the proposed research programme and the availability of local supervision.

The Clore Laboratory is situated in the attractive and rural environment of Buckingham, at the heart of the University campus.

Find out more about our Medical School on http://www.buckingham.ac.uk/medicine.

Research Degrees

DPhil

This is a three-year research programme, the student being initially admitted to an MPhil/DPhil track. Progress from MPhil to DPhil registration is subject to assessment after 18 months. The research programme will be a substantial piece of independent work and will have made an original and significant contribution to knowledge. Examination is by thesis submission and external viva voce .

MPhil

This is a two-year research project with submission of a thesis and viva voce (oral) examination. The research will not have the same depth as a DPhil but will still be an original piece of work.

Supervision

Supervision of postgraduate students is under the control of the Director. On a day-to-day basis students will be supervised in the laboratory by an experienced researcher.

Apply here http://www.buckingham.ac.uk/bitm/postgraduate.

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This rewarding research-based programme will prepare you for a career in nutrition research, clinical environment or the health industry. Read more

Summary

This rewarding research-based programme will prepare you for a career in nutrition research, clinical environment or the health industry. With an increasing need for research experts in nutrition, collaborate with internationally renowned experts in the field to tackle modern metabolic diseases and the impact on human health.

This specialist programme offers a highly topical theoretical and practical training in the science behind nutrition in preparation for your rewarding career within health research, a clinical environment or the health industry.

With the imminent global obesity crisis and the associated increase in human metabolic disorders, there is increasing demand for interventions and experts who can offer solutions for healthy diets and nutrition to tackle these issues.

You will be taught by renowned experts in the field who have made an impact in topical areas of nutrition and metabolism. You will also conduct your own research and could choose from a variety of research topics including: the gut microbiota, Polypehnols and cardiovascular disease, the impact of meal times, the importance of breakfast, type 2 diabetes- insulin secretion and beta cell survival, dietary interventions for obesity, Polycystic Ovary Syndrome and the endocrine regulation of appetite and bodyweight.

The development of your research methods skills is an integral part of the course. You will further your understanding of modern nutrition research with a project which will give you not only experience of specialist research techniques, but also skills in research design and data handling and analysis with the use of statistics.

As a member of the course, you will join the Health Sciences Research Centre and will be encouraged to attend research seminars and lab meetings led by experts who are currently investigating a range of cutting-edge developments in Nutrition and health sciences.

Content

This programme is a research based postgraduate degree which offers research training in nutrition and metabolism with a focus on a research project in a current topical area. The programme has a strong background of research methods with emphasis on research design, ethics and statistical methods. Subject-specific lectures, seminars, tutorials and practical work will both introduce and prepare you for recent advances in the field, both theoretical and technological and their applications in Nutrition.

This modern and unique postgraduate programme prepares you for careers in nutrition and metabolism research: academia, clinical research, industry or government, and forms an excellent foundation for PhD studies.

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Medical Life Sciences is an English-taught two-year Master’s programme in molecular disease research and bridges the gap between the sciences and medical studies. Read more
Medical Life Sciences is an English-taught two-year Master’s programme in molecular disease research and bridges the gap between the sciences and medical studies. You will get to know clinical research from scratch; you will learn how to investigate diseases/disease mechanisms, how to translate research results into prevention, diagnosis and therapies of diseases.
From the basics of medical science to lab experiments for the Master’s thesis, individual scientific training takes first priority. Experimental work in state-of-the-art research labs is essential in Medical Life Sciences; clinical internships, data analysis, lectures, seminars and elective modules complement the Medical Life Sciences curriculum.

To lay the foundation for working in medical research, Medical Life Sciences (MedLife) provides basic knowledge in courses on clinical manifestations of diseases, human biology, molecular pathology and immunology. Lectures, seminars and tutorials in molecular biology, bioinformatics, clinical cell biology, medical statistics, and human genetics broaden your knowledge and make the interfaces between medicine and the sciences visible. You will learn how to acquire knowledge, verify and use it, all of which are important skills in research.

Focus Areas

From the second semester, you additionally specialise in one of the following focus areas:

INFLAMMATION takes you deep into the molecular mechanisms of chronic inflammatory diseases, the causal network between inflammatory processes and disease, genetics and environment. New research results for prevention, diagnosis and therapy will be presented and discussed. An internship in specialised clinics helps to see how “bed to bench side”, i.e. translational medicine, works.

EVOLUTIONARY MEDICINE looks at how interrelations between humans and their environment have led to current disease susceptibility. Why do we suffer from chronic diseases such as diabetes, heart disease and obesity? Is our lifestyle making us sick? Why are certain genetic variants maintained in populations despite their disease risk? Evolutionary medicine focuses on bridging the gap between evolutionary biology and medicine by considering the evolutionary origins of common diseases to help find new biomedical approaches for preventing and treating them.

LONGEVITY focuses on molecular mechanisms that seem to counteract the detrimental effect of ageing. The disease resilience and metabolic stability of extraordinarily fit people well over 90 years of age are of special interest. This research is complemented by experiments on model organisms. You will also look at the molecular pathways of ageing, and which role genes and the environment play. How the intricate web of counteracting effects triggering ageing and/or longevity works stands as the central focus of this area.

ONCOLOGY delves deep into molecular research on malignant diseases, the interplay of genetics and environment, cell biology of tumours, and many other aspects. You will achieve a better understanding of unresolved problems and opportunities of current research approaches.

Scientists and clinicians will make you familiar with these topics in lectures and seminars. You will discuss different research approaches, perspectives and the latest developments in medical research. Lab practicals in state-of-the-art research labs, a lab project, and the experimental Master's thesis will provide ample opportunity to be involved in real-time research projects.

Electives

To widen your perspective, you choose one of three electives designed to complement the focus areas. The schedules are designed so that you can take part in more than one elective if places are available. Tracing Disease through Time looks at disease etiology by analysing biomolecules, diets and pathogens in archaeological specimens. You may opt for Epidemiology to immerse yourself in epidemiological approaches with special emphasis on cardiovascular diseases, one of the greatest health threats in modern societies. Another option is Molecular Imaging, which gives you insight into the world of high-tech imaging in medical research.

Additional electives such as Neurology, Tissue Engineering or Epithelial Barrier Functions and Soft Skills courses such as Project Management, Career Orientation and English Scientific Writing are integrated into the curriculum during the entire duration of your studies.

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There is a global epidemic of diabetes and obesity and health professionals need to understand these diseases and be equipped to manage them. Read more
There is a global epidemic of diabetes and obesity and health professionals need to understand these diseases and be equipped to manage them. Our program is developed and delivered by international leaders in the field of diabetes and metabolic health. It provides understanding of and methods to manage diabetes, obesity and associated cardiovascular complications in the general population as well as particular groups, such as pregnant women.

This course will provide you with a unique opportunity to study with your peers and network with clinical and academic leaders. We adopt a case‑based format and offer online tutorials to facilitate discussion and analysis.

This degree is suited to pharmacists and nurses with an interest in the field.

Face-to-face teaching is delivered in the University’s new state-of-the-art Charles Perkins Centre research and education hub.

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There is a global epidemic of diabetes and obesity and clinicians need to understand these diseases and be equipped to manage them. Read more
There is a global epidemic of diabetes and obesity and clinicians need to understand these diseases and be equipped to manage them. Our program is developed and delivered by international leaders in the field of diabetes and metabolic health. It provides understanding of and methods to manage diabetes, obesity and associated cardiovascular complications in the general population as well as particular groups, such as pregnant women.

This course will provide you with a unique opportunity to study with your peers and network with clinical and academic leaders. We adopt a case‑based format and offer online tutorials to facilitate discussion and analysis.

This degree is suitable for medical practitioners working in primary care, emergency medicine, paediatrics and those planning to train in endocrinology.

Face-to-face teaching is delivered in the University’s new state-of-the-art Charles Perkins Centre research and education hub.

To ask a question about this course, visit http://sydney.edu.au/internationaloffice/

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Evolutionary Medicine is a growing and exciting new field that is highly interdisciplinary in nature. We offer the only MSc in Evolutionary Medicine in the world, taught by a unique grouping of world-class researchers specialising in evolutionary approaches to the study of health and disease. Read more
Evolutionary Medicine is a growing and exciting new field that is highly interdisciplinary in nature. We offer the only MSc in Evolutionary Medicine in the world, taught by a unique grouping of world-class researchers specialising in evolutionary approaches to the study of health and disease. A major theme of the course is the mismatch between the environment in which humans evolved and the contemporary environment, and implications for obesity and related metabolic disorders, reproductive health and infant care. Optional courses are offered in palaeopathology and cultural evolution, and in the wider anthropology of health.

Course content

The programme is designed for students preparing for doctoral research in evolutionary medicine, or for those who would like to apply an evolutionary perspective to their work in health. It is a popular intercalated degree for medical students.

The course is suitable for those with an undergraduate degree in anthropology, psychology, biology, health sciences, nutrition or a related discipline, and for health professionals.

Evolutionary Medicine is a growing and exciting new field that is highly interdisciplinary in nature. We currently offer the only MSc in Evolutionary Medicine in the world, taught by a unique grouping of world-class researchers specialising in evolutionary approaches to the study of health and disease. A major theme of the course is the mismatch between the environment in which humans evolved and the contemporary environment, and implications for obesity and related metabolic disorders, reproductive health and infant care. Optional modules previously offered included palaeopathology and cultural evolution, and in the wider anthropology of health.

The full-time course runs for a full year, from October to September. Students attend classes between October and December (Michaelmas Term) and January and March (Epiphany), with further teaching and assessment in April and May (Easter Term), and then work, under the supervision of a specialist supervisor, to complete a dissertation in September. Students take three core taught modules, designed to provide a foundation in evolutionary theory, quantitative methods used in evolutionary medicine, and an introduction to evolutionary medicine. There is also a range of optional modules available to allow students to focus on areas of particular interest.

Each module we offer has a credit value. To obtain a Master’s degree you must register for and pass modules to the value of 180 credits. In recognition of the emphasis we place on independent research skills, the dissertation is a 60 credit module.

Compulsory modules:
-Dissertation
-Evolutionary Theory
-Evolutionary and Ecological Topics in Medicine and Health
-Statistical Analysis in Anthropology

Previous optional modules have included:
-Academic and Professional Skills in Anthropology
-Evolutionary Perspectives on Western Diseases
-Public Health Anthropology
-Anthropology of Global Health
-Cultural Evolution
-Evolutionary Psychology
-Themes in Palaeopathology
-Evolutionary Perspectives on Reproductive and Infant Health
-Foreign language option.

Please see http://www.durham.ac.uk/anthropology/postgraduatestudy/taughtprogrammes/evolutionarymedicine for further information on modules.

Learning and Teaching

Evolutionary Medicine is a growing and exciting new field that is highly interdisciplinary in nature. We offer the only MSc in Evolutionary Medicine in the world, taught by a unique group of world-class researchers specialising in evolutionary approaches to the study of health and disease. A major theme of the course is the mismatch between the environment in which humans evolved and the contemporary environment, and implications for obesity and related metabolic disorders, reproductive health and infant care. Optional courses are offered in palaeopathology and cultural evolution, and in the wider anthropology of health.

The course runs for a full year, from October to September. Students attend classes between October and December (Michaelmas Term) and January and March (Epiphany), with further teaching and assessment in April (Easter Term), and then work, under the supervision of a specialist supervisor, to complete a dissertation in September. Students take three core taught modules, designed to provide a foundation in evolutionary theory, quantitative methods used in evolutionary medicine, and an introduction to evolutionary medicine. There is also a range of optional modules available to allow students to focus on areas of particular interest.

Each module we offer has a credit value. To obtain a Master’s degree you must register for and pass modules to the value of 180 credits. In recognition of the emphasis we place on independent research skills, the dissertation is a 60 credit module.

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The course involves the detailed study of the physiological consequences of chronic debilitating diseases and highlights the changes that these different diseases cause during exercise testing. Read more
The course involves the detailed study of the physiological consequences of chronic debilitating diseases and highlights the changes that these different diseases cause during exercise testing.

This unique course gives you a solid grounding in theory and application of physiological tests in clinical populations including: graded cardiopulmonary exercise testing; cardiac ultrasound; vascular ultrasound; and muscle function analyses; as well as practical and theoretical elements of Phase IV cardiac rehabilitation.

Throughout the course you will actively participate in practical sessions designed to increase your skills, with supervised practice sessions working alongside University sports teams. Integration of theory and practice ensures you will meet developing statutory professional requirements of practice-specific knowledge, understanding and skills.

Intermediate qualifications available:

• Postgraduate diploma – 120 credits at Masters level https://www.beds.ac.uk/howtoapply/courses/postgraduate/next-year/clinical-exercise-physiology3

• Postgraduate certificate – 60 credits at Masters level

Visit the website: https://www.beds.ac.uk/howtoapply/courses/postgraduate/next-year/clinical-exercise-physiology

Course detail

• Study on a unique course with a multi-disciplinary approach to teaching, with access to world-leading staff expertise and research
• Explore areas including: research design; exercise testing and diagnosis; exercise testing and prescription; physical activity, nutrition and metabolic health; laboratory skills; research methods; advanced exercise testing and diagnosis
• Develop the high-level professional standards demanded of members of a health care team; understanding your ethical, moral and legal responsibilities as well as acquiring the practical competencies, theoretical knowledge and research skills that will help you access careers in health and fitness or academia
• Gain from the opportunity to practice your skills on work placement, and shadow experienced staff
• Benefit from gaining the necessary skills to become a Health Promotion Specialist; Clinical Exercise Physiologist; Clinical Technician or researcher, and/or continue to further research-based study on MSc by research, MPhil or PhD programmes.

Modules

• Laboratory Skills
• Cardiopulmonary Exercise Testing and Interpretation
• Exercise Testing and Diagnosis
• Exercise Prescription for Clinical Populations
• Research Methods
• Clinical Exercise Physiology Dissertation
• Psychological Approaches to Public Health*
• Professional Skills for Healthcare Providers*
• Metabolic Health*
• Sport Science Support*
• Placement (short)*
• Placement (long)*
*denotes options

Assessment

A variety of assessment formats are used and are designed to develop your transferable skills such as written and oral communication, the ability to follow logical instructions, problem solving and time management.

Some assessments are designed to mimic the scenarios that you may find in the clinical environment, such as practical exams, assess client care, technical skills, analysis and interpretation of test results.

All of these assessments are considered to be the best method to assess the learning outcomes of the particular unit, as well as developing professional and transferable skills.

• Written assessments – dissertation, projects, reports, lab reports (approx. 85%)
• Exams and tests (5%)
• Presentations and practicals (approx. 10%)

Careers

You will experience hands-on practical experience from the start of the course developing confidence for meeting and assessing patients in the clinical setting.

You will be introduced to a range of specialist equipment that you become competent in, allowing you to transfer your practical skills to clinical environment.

The placement units allow you to experience the clinical setting and different clinical populations.

Clinical practitioners deliver some of the lecture and practical content ensuring that you can receive insight into the setting in which you are likely to work.

Graduates can to apply for positions such as: Health Promotion Specialist, Clinical Exercise Physiologist, Clinical Technician. Previous graduates have gone on to train as cardiologists, including a specialist in congenital and adult heart disease in the Evelina Children’s Hospital and Guy's and St Thomas’.

You could also apply for further study, such as a PhD or the NHS Scientific Training Programme.

Funding

For information on available funding, please follow the link: https://www.beds.ac.uk/howtoapply/money/scholarships/pg

How to apply

For information on how to apply, please follow the link: https://www.beds.ac.uk/howtoapply/course/applicationform

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The MRes in Biomedical Research - Molecular Basis of Human Disease provides training and teaching in multidisciplinary approach to understand disease mechanisms. Read more
The MRes in Biomedical Research - Molecular Basis of Human Disease provides training and teaching in multidisciplinary approach to understand disease mechanisms. The emphasis of the MRes is on a broad range of training from structural and chemical biology to clinical applications in order to gain knowledge across the biological scales from atoms, molecules to whole cell/organisms on pressing human diseases such as cancer, cardiovascular and pulmonary diseases, metabolic and cellular disease as well as pathogen infection and resistance.

Like the other MRes streams, this course exposes students to the latest developments in the field through two research projects that are complementary in training, with one focusing on molecular mechanism while the other one on disease pathways and/or clinical applications. This course is further supplemented by lectures, tutorials and seminars.

Students will gain experience in applying technologically advanced approaches to biomedical questions. Individuals who successfully complete the course will have developed the ability to:

-Perform novel laboratory based research and exercise critical scientific thought in the interpretation of results.
-Undertake two research projects in line with the multidisciplinary culture of the Section and Division.
-Demonstrate practical and intellectual dexterity in the research project elements.
-Develop an appreciation of cutting edge technologies addressing molecular mechanisms and current understanding of key diseases pathways and mechanisms.
-Be able to interpret and present scientific data
-Be able to interrogate relevant scientific literature and develop research plans.
-Be able to write a grant application, through the taught grant-writing exercise common to all MRes streams.
-Be able to write and defend research reports through writing, poster presentations and seminars.
-Exercise a range of transferable skills by taking a minimum number of short courses taught through the Graduate School.

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Gain the essential skillsets as a nutritionist to help improve people’s health and well-being in the context of the malnutrition, obesity, metabolic response to injury and chronic disease. Read more

Summary

Gain the essential skillsets as a nutritionist to help improve people’s health and well-being in the context of the malnutrition, obesity, metabolic response to injury and chronic disease.

This was the first MSc in Clinical Nutrition to be established in the UK and has gained an international reputation, attracting students from around the world. You will consider the patient’s journey from birth to extreme age in the context of the metabolic response to injury or to chronic disease. The course is designed for all members of nutrition support teams and is also suitable for students who wish to pursue clinically-based nutrition research.

After establishing a firm foundation in physiology and the biochemistry of nutrition, this course will cover the nutritional management for clinical conditions such as gastro-enteral problems, long-term disablement and intensive care. It also includes a focus on nutrition support in paediatric, adult, older adult and critically ill patients.

This course is perfect for nutrition support teams or those who want to pursue a career or a doctorate in clinically-based nutrition. The course will provide an important insight into contemporary developments in clinical nutrition for a wide range of healthcare professionals.

You will have access to our state-of-the art facilities and excellent laboratories including a food lab complete with sensory analysis tasting booths and specialist laboratories for physiology, microbiology and computing.

Please note this programme does not lead to a qualification in the UK as a registered Dietitian. It is an accredited course with the Association for Nutrition, and does enable you to become a registered nutritionist, once you have complete two years in the nutrition field.

Content

We offer a diverse range of modules to build your knowledge and enable you to focus on topics that interest you. Recent examples of these topics have included: macronutrient and micronutrient metabolism in health and disease, nutrient digestion and absorption and gastrointestinal disease, nutritional support in paediatric, adult, older adult and critically ill patients, the effect of disease on nutrition status.

Research areas that are also included in the programme are dietary management strategies in women with polycystic ovary syndrome; the role of brain–gut interaction in obesity, eating disorders, and irritable bowel syndrome; the role of the enteric nervous system in known intestinal diseases; vitamin E status in health and disease; the role of microbiota in food and nutritional systems; food bioactives for a healthy gut, brain and vascular system; the regulation of insulin secretion and glucose metabolism in health and diabetes.

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The two-year MSc Bioinformatics concerns a new scientific discipline with roots in computer science, statistics and molecular biology. Read more

MSc Bioinformatics

The two-year MSc Bioinformatics concerns a new scientific discipline with roots in computer science, statistics and molecular biology. Bioinformaticians apply information technology to store, retrieve and manipulate these data and employ statistical methods capable of analysing large amounts of biological data to predict gene functions and to demonstrate relationships between genes and proteins.

Programme summary

DNA contains information about life, but how is this information used? Biological data, such as DNA and RNA sequence information produced by next-generation sequencing techniques, is accumulating at an unprecedented rate. Life scientists increasingly use bioinformatics resources to address their specific research questions. Bioinformaticians bridge the gap between complex biological research questions and this complex data. Bioinformaticians use and develop computational tools to predict gene function(s) and to demonstrate and model relationships between genes, proteins and metabolites in biological systems. Bioinformatics is an interdisciplinary field that applies computational and statistical techniques to the classification, interpretation and integration of large-scale biological data sets. If different data types are joined then complex interactions in biological systems can be studied. The use of systems biology methods to study complex biological interactions offers a wealth of possibilities to understand various levels of aggregation and enables control of biological systems on different scales. Systems biology approaches are therefore quickly gaining importance in many disciplines of life sciences, such as in applied biotechnology where these methods are now used to develop strategies for improving production in fermentation. Other examples include bioconversion and enzymatic synthesis, and in the study of human metabolism and its alterations where systems biology methods are applied to understand a variety of complex human diseases, including metabolic syndromes and cancer. The Wageningen Master programme focuses on the practical application of bioinformatics and systems biology approaches in many areas of the Life Sciences. To ensure that students acquire a high level of understanding of modelling and computing principles, the students are trained in the fundamentals of database management, computer programming, structural and functional genomics, proteomics and systems biology methods. This training includes advanced elective courses in molecular biology and biostatistics.

Thesis tracks

Bioinformatics
The bioinformatics track focuses on the practical application of bioinformatics knowledge and skills in molecular life sciences. It aims at creating and using bioinformatics resources to address specific research questions. The knowledge and skills gained can be applied in many life science disciplines such as molecular & cell biology, biotechnology, (human) genetics, health & medicine and environmental & biobased technology.

Systems Biology
The systems biology track focuses on the study of the complex interactions in biological systems and on the emerging properties derived from these. Systems biology approaches to complex biological problems offer a wealth of possibilities to understand various levels of aggregation. It enables control of biological systems on completely different scales, ranging from the molecular cellular level to marine, plant, or animal ecosystems to a desired state. The knowledge and skills gained can be applied in many life science disciplines including molecular & cell biology, applied biotechnology, genetics, medicine and vaccine development, environmental and biobased technology.

Your future career

Bioinformatics and Systems Biology are new fast growing biology based interdisciplinary fields of research poorly served by the traditional curricula of Life Sciences. As demand has outpaced the supply of bioinformaticians, the first job after graduation is often a PhD project at a research institute or university. It is expected that five years after graduation, about one third will stay employed as a scientist at a university or research centre, while the others choose for careers at research-oriented pharmaceutical and biotechnological companies.

Alumnus Tom van den Bergh.
"It is sometimes difficult for doctors to diagnose genetic diseases caused by missense mutations. A missense mutation does not necessarily mean that you have the gene-associated disease and will become ill since not all missense mutations lead to appreciable protein changes." Tom created a database for Fabry’s disease for his final thesis. He wrote a computer programme that reads publications and stores all information about Fabry mutations in its database. Genetic researchers can, in turn, quickly access this database to determine if the mutation they found in a patient has already been addressed in literature and what the effects were.

Related programmes:
MSc Biotechnology
MSc Molecular Life Sciences
MSc Plant Biotechnology

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Study how stress affects illness and examine ways to improve individual wellbeing through practical applications in stress management. Read more

Summary

Study how stress affects illness and examine ways to improve individual wellbeing through practical applications in stress management.

Our programme is designed for graduates in psychology and the biological sciences, and professionals from a range of backgrounds including healthcare and counselling. You will gain a robust science-based qualification in the study of stress, dealing specifically with the mechanisms by which psychological stress can induce illnesses and examining issues of measurement, prevalence and management. This is especially pertinent today as you will study occupational stress and management for people in the workplace.

Taught by leading experts in the field, you will learn about how stress medicine and psychoneuroimmunology are growth areas in the discipline. You will be able to conduct and present your research project in an area of your interest. There will be an opportunity to gain practical, hands-on experience by recruiting a sample group of subjects for a stress assessment. You will then produce an assessment report which will form the basis of risk assessment and guidance for intervention.

You will gain access to state-of-the-art laboratories and resources for conducting research projects.

Content

In your first semester, you will develop a strong understanding how psychological states can affect physical wellbeing, in particular the role of stress in the development of various diseases, such as coronary heart disease and metabolic disorders including diabetes and mental illnesses. You will gain an in-depth understanding of the health care field and the current developments in stress management.

After the first semester, the emphasis will be on independent study, and you will undertake an in-depth piece of original research. You will learn to collect, combine and analyse data from a range of sources, making critical assessments as you progress. Hands-on experience gained in the recruitment of test group will be invaluable experience for your career in the healthcare.

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Many patients who go to the dental surgery to receive dental treatment are of an advanced age, with systemic illnesses which require accurate knowledge… Read more
Many patients who go to the dental surgery to receive dental treatment are of an advanced age, with systemic illnesses which require accurate knowledge of them and their implications and interactions in the field of dentistry, or with cardiovascular, immunological, endocrinal and metabolic pathologies, which the dentist must understand to provide treatment correctly, in a manner that is safe to both patient and dentist. Likewise, those with any type of disability present complex challenges that are difficult for dentists to resolve. In addition to this is the appearance of secondary oral lesions as a result of taking certain medications or interactions between them, or as oral manifestations of underlying systemic diseases. All of these are considered special patients.

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Preventative Cardiovascular Medicine is a rapidly evolving branch of medicine involved in the prevention of cardiovascular diseases such as stroke, coronary heart disease and peripheral vascular disease. Read more
Preventative Cardiovascular Medicine is a rapidly evolving branch of medicine involved in the prevention of cardiovascular diseases such as stroke, coronary heart disease and peripheral vascular disease.

This masters online course is designed to be practical and clinically focused and will focus on applying scientific principles to direct patient care. It aims to create professionals who can independently access information and use the information to critically assess, evaluate and disseminate the evidence base related to Preventative Cardiovascular Medicine. It will develop problem solving and clinical skills together with preparing students to take a leadership role.

On completion of the course, you will be able to:
- Deliver management strategies for the investigation and treatment of patients at increased cardiovascular risk.
- Demonstrate knowledge and competence in Preventative Cardiovascular Medicine.
- Develop and deliver Preventative Cardiovascular interventions for the wider population.

See the website http://courses.southwales.ac.uk/courses/1797-msc-preventative-cardiovascular-medicine-online-delivery

Facilities

As part of your online studies you will have access to the Learning Resources Centre materials at the University of South Wales. FINDit is the University’s portal which allows you to search for over 13,000 full-text journal articles, news articles, conference proceedings and approximately 160 databases via one search box- the majority of these materials are accessible online. Interactive study skills modules are available to study via Blackboard to enable you to utilise the library services fully.

Teaching

You will be taught by healthcare professionals who are recognised experts in Preventative Cardiovascular Medicine and are experienced in delivering online learning:

- Dr. Alan Rees – Consultant Physician, RCP vice president for Wales, Medical Director HEART UK

- Dr. Dev Datta – Consultant in Medical Biochemistry and Metabolic Medicine

- Dr. Ian McDowell – Senior Lecturer and Consultant, Chair of Familial Hypercholesterolaemia (FH) Wales Cascade Service, Chair of FH Wales Professional Advisory Group

- Dr. Devaki Nair– Consultant Lipidologist and Chemical Pathologist

- Dr. Steve Davies – Consultant Endocrinologist and Director of Diploma MSc

Work and Study Placements

Students will usually be employed as health care professionals before commencing this course. Consequently work or study placements are not available.

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Preventative Cardiovascular Medicine is a rapidly evolving branch of medicine involved in the prevention of cardiovascular diseases such as stroke, coronary heart disease and peripheral vascular disease. Read more
Preventative Cardiovascular Medicine is a rapidly evolving branch of medicine involved in the prevention of cardiovascular diseases such as stroke, coronary heart disease and peripheral vascular disease. Our postgraduate diploma online course aims to create professionals who can independently access information and use the information to critically assess, evaluate and disseminate the evidence base related to Preventative Cardiovascular Medicine. It will develop problem solving and clinical skills together with preparing students to take a leadership role in this medical area.

On completion of the course you will be able to:
- Demonstrate advanced knowledge and competence.
- Deliver management strategies for the investigation and treatment of patients at increased cardiovascular risk.
- Develop and deliver interventions for the wider population and safely use preventative cardiovascular approaches in specific cases.

See the website http://courses.southwales.ac.uk/courses/1798-postgraduate-diploma-in-preventative-cardiovascular-medicine-online-delivery

What you will study

The course consists of 6 modules per year, each of 6 weeks duration:

Principles of Preventative Cardiovascular Medicine (20 credits)
This module focuses on the science underpinning preventative cardiovascular medicine and the assessment of cardiovascular risk as applied to clinical practice.

Cardiovascular Risk Management (20 credits)
This modules aims to develop a critical understanding of nutrition and lifestyle factors in the development of cardiovascular disease.
- Lipid Metabolism in Clinical Practice (20 credits)*
This module develops a comprehensive understanding of lipid metabolism and disorders, and their presentation and assessment in clinical practice.

Management of Lipid Disorders (20 credits)
This module ensures that students develop a comprehensive understanding of lipid metabolism and disorders, and their presentation and assessment in clinical practice.

Hypertension: Diagnosis and Management (20 credits)
This module enables students to develop a critical understanding of the pathophysiology and management of hypertension.

Preventative Cardiovascular Medicine in Special Situations (20 credits)
This module involves gaining a critical understanding of preventative cardiovascular medicine in a wide range of relevant clinical conditions.

Learning and teaching methods

Each of the 6 modules is taught online and includes self-directed learning, tutor stimulated discussion on case scenarios, examinations, group projects and independent projects. Reflective practice is also studied which involves considering how you can apply the knowledge gained into everyday work and practice.

Work Experience and Employment Prospects

The course promotes and enhances professional skills and knowledge among its students that have direct relevance and application to the demands of their working roles. There is increasing competition for employment in the healthcare arena, with increasing specialisation. It is envisaged that students will be GPs, medical trainees in Diabetes, Vascular surgery, Cardiology, Medical Biochemistry in addition to Allied Health Professionals, and Practice Nurses running CV clinics.

Assessment methods

Assessment methods will vary for each module and include case-based examinations, discussions and scenarios, reflective portfolio, forum discussions and group activities.

Facilities

As part of your online studies you will have access to the Learning Resources Centre materials at the University of South Wales. FINDit is the University’s portal which allows you to search for over 13,000 full-text journal articles, news articles, conference proceedings and approximately 160 databases via one search box, the majority of these materials are accessible online. Interactive study skills modules are available to study via Blackboard to enable you to utilise the library services fully.

Teaching

You will be taught by healthcare professionals who are recognised experts in Preventative Cardiovascular Medicine and are experienced in delivering online learning:
- Dr. Alan Rees – Consultant Physician, RCP vice president for Wales, Medical Director HEART UK
- Dr. Dev Datta – Consultant in Medical Biochemistry and Metabolic Medicine
- Dr. Ian McDowell – Senior Lecturer and Consultant, Chair of Familial Hypercholesterolaemia (FH) Wales Cascade Service, Chair of - FH Wales Professional Advisory Group
- Dr. Devaki Nair– Consultant Lipidologist and Chemical Pathologist
- Dr. Steve Davies – Consultant Endocrinologist and Director of Diploma MSc

Work and Study Placements

Students will usually be employed as health care professionals before commencing this course. Consequently work or study placements are not available.

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