The Centre for Integrative Physiology (CIP) fosters research into fundamental mechanisms and pathways relevant to human function and disease.
CIP investigators exploit rapid advances in the enabling technologies available from genomics, proteomics, imaging, informatics, and in vivo analysis to understand the function of gene products at the cell, organ and whole-animal level.
Importantly, CIP investigators exploit the most appropriate model organisms/systems to investigate the key physiological question being posed: a delicate balance between high biomedical relevance (for example human, mouse, rat) and high genetic power (such as Drosophila and fish).
Our MSc by Research is a full-time 1-year research project done under the supervision of a CIP Researcher. This programme has no taught component and is therefore only suitable for highly motivated students with a clear idea of their research interests and goals, with significant theoretical or practical knowledge of a chosen field. An MSc by full-time research provides an excellent training in laboratory research and a strong grounding for further study at the level of PhD. Initial enquires should be made directly to [email protected].
MSc students will work full-time on their research project with the additional option of taking selected transferable skills courses. Each student will have two supervisors. After 3 months study a short presentation and report of completed and proposed work will be made to the supervisors, at which point progression from Diploma to full Masters will be considered. Students that demonstrate sufficient progress and aptitude will progress for a further 9 months full-time research after which a Dissertation will be presented and assessed for the award of MSc.
If you're interested in applying for the MSc by Research, please review the Research Profiles and recent publications from members of the CIP:
A preliminary email briefly outlining your research interests and identifying up to three potential supervisors from the CIP should be sent directly to Dr Paul Skehel. If appropriate, students will then be invited to submit a short 400-word general outline for a potential MSc project with specific supervisors. Applicants progressing to this point will then be guided to make a formal application on this page. Please note that the MSc by Research has additional programme costs of £5,000.
The core of the CIP occupies the newly refurbished Hugh Robson Building and has facilities for all aspects of modern molecular, cellular and systems biology.
Research is mainly funded by grants from the MRC, the BBSRC and industrial companies.
We offer a comprehensive research programme suitable for PhDs and MScs covering a diverse range of musculoskeletal disorders.
There are ongoing projects in the following areas:
Students are assigned to the relevant research group. Each student's progress is monitored by a thesis committee convened from members within these groups. Students participate in a monthly graduate seminar programme, presenting their analysis of original research. All students are encouraged to present their findings at national and international conferences and to publish their findings in international journals, in advance of submission of their PhD theses for examination.
The orthopaedic engineering unit and the musculoskeletal research unit along with the microCT facilities are based within the Chancellor's Building. Facilities for collaborative projects are based in the centre for regenerative medicine and the centre for integrative physiology. The outcome performance assessment facilities are based within the clinical department in the Royal Infirmary.
Translating fundamental biomedical discoveries into applied clinical practice and public health issues
Human Biology is the only specialisation in the Netherlands that combines fundamental human biology with clinical studies. It provides you with an extensive biological knowledge, and experience in working with animal and patient samples. In this way you’ll be trained to bridge the gap between early biomedical research results and clinical practice.
This wouldn’t be possible within the walls of the Faculty of Science. That’s why there’s an extensive collaboration between the Faculty of Science and the Radboud university medical center in the field of Human Biology. You’ll get the best of both worlds: a thorough background in for example molecular oncology, human genetics, physiology and metabolism as well as a clinical view on diseases. This is an excellent background for a medical researcher or a job at the interface of science and society, such as a consultant, policy officer or communications advisor in the area of food or health.
See the website http://www.ru.nl/masters/humanbiology
- It is the only programme in the Netherlands that bridges the gap between fundamental biomedical research and clinical treatments.
- You’ll get the opportunity to work together with researchers from the Radboud university medical center.
- Radboud biologists and clinicians stand out in the fields of animal and human physiology, human genetics and disease, and molecular and cellular clinical studies.
- Clinical Biology offers internships at multiple related research institutes, such as the Radboud Institute for Molecular Life Sciences (RIMLS), the Radboud Institute for Health Sciences (RIHS) and the Donders Institute for Brain, Cognition and Behaviour (DI).
- There are various opportunities to do an internship abroad thanks to our wide network of cooperating research groups.
After graduation, our students quickly take up positions as researchers in government departments, research organisations and medical or pharmaceutical companies. However, many of our graduates also apply their academic background to societal issues, for example as a communications or policy officer. In general, clinical biologists end up as a:
- Researcher in a hospital or a university
- Researcher in a company, either a large or a start-up company
- Supervisor of clinical trials
- Consultant in the area of health or food
- Policy officer in the area of health or food
- Communications officer at a hospital or a governmental organisation, like RIVM
- Teacher in biology or medical biology
PhD positions at Radboud University
Each year, Radboudumc offers PhD positions in this field of research. Of course, many graduates also apply for a PhD position at related departments in the Netherlands, or abroad.
- From human biology to clinical treatment
Human Biology at Radboud University connects fundamental biological research to clinical treatments. The courses will provide you with a solid background in human physiology and molecular biology, which you’ll apply in developing clinically-oriented research questions. As there’s an extensive collaboration between the Faculty of Science and the Radboud university medical center, you’ll become familiar with both perspectives.
In your internships you’ll work with biomaterials, such as patient and animal samples. This means you’ll apply your biological knowledge to real-life situations. Clinical biologists do not work with patients or clinical treatments directly.
- Three focus areas
This Master’s specialisation focuses on three main topics:
- Molecular Mechanisms of Novel Therapeutics
Which molecular mechanisms lead to cancer? And how can these be translated into clinical practice? These are key questions in the specialisation in Human Biology. For example, we’ll dive into the functioning of epigenetics (heritable modifications of chromosomes without altering the nucleotide sequence), transcription factors, tumour suppressors and immunotherapy.
- Human Genetics and Physiology
This part is about how new developments and discoveries in genetic and molecular fields can help individual patients to improve functionality, independence and quality of life. You’ll study genetic pathways and the functionality of individual organs, organ systems, regulatory mechanisms, and individuals as a whole, in an integrative way.
- Metabolism, Transport and Mobility
The energy balance in our body is one of the most important factors in health and disease. We’ll teach you how energy and metabolites are integrated into the larger cellular networks for metabolism, transport and motility.
See the website http://www.ru.nl/masters/humanbiology