Masters Degrees (Human Genetics)

Research profile

The MRC Human Genetics Unit (HGU), is part of the Institute of Genetics and Molecular Medicine (IGMM) within the College of Medicine and Veterinary Medicine at the University of Edinburgh. As well as delivering outstanding research, the institute creates a vibrant scientific community and a friendly research environment rich in both scientific and social opportunities.

The aim of the MRC Human Genetics Unit is to advance the understanding of genetic factors implicated in human disease and normal and abnormal development and physiology. Our PhD and MSc programmes harnesses strengths in different research disciplines (genetics, molecular biology, biochemistry and cell biology) tied to our scientific themes (disease mechanisms, biomedical genomics and genome regulation). Our program also provides a strong focus on computational biology, and state of the art imaging as part of the Edinburgh Super-Resolution Imaging Consortium. Over 30 principal investigators based in the MRC HGU contribute to these cross-disciplinary programmes spanning fundamental to clinical research.

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The Master of Medicine (Reproductive Health Sciences and Human Genetics) and Master of Philosophy double degree is a coursework master’s degree combined with a master’s degree by research. You will enrol part-time in both coursework study and research study at the same time to complete this double degree as a full-time student over two years. The Master of Philosophy is completed under the guidance of a supervisor.

The double degree is available only to international students. Local students may enrol part-time in the two single degrees simultaneously, or they may enrol in the two degrees sequentially. In the latter instance, local students will complete both degrees part-time over four years.

To ask a question about this course, visit http://sydney.edu.au/internationaloffice/

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The Faculty of Medicine of Memorial University of Newfoundland, one of 17 Canadian medical schools, was established in 1967. The Faculty is housed within the Health Sciences Centre in St. John’s, a modern facility which also includes the adult and women’s hospital, the Janeway Children’s Hospital, the H. Bliss Murphy Cancer Centre, and the Schools of Nursing and Pharmacy, plus specialized units and support services. The graduate programs in the Faculty of Medicine are structured to create an academic environment conducive to research training excellence. The programs are designed to provide formal instruction as well as to promote informal exchange in areas of health and health research. There are nine areas of concentration in graduate studies in the Faculty of Medicine: Applied Health Services Research, Cancer Research, Cardiovascular and Renal Sciences, Clinical Epidemiology, Community Health, Human Genetics, Immunology and Infectious Diseases, Neuroscience, and Public Health.

These programs are based upon focal areas of health research within the Faculty and are dependent upon a critical mass of actively engaged faculty researchers in these areas. Each area of concentration has a program coordinator chair or director, and includes a core of graduate courses appropriate to the area of health research and mechanisms for formal and informal exchange of research ideas (journal clubs, seminar series, visiting speakers program). In addition to course work and thesis requirements, the broad education of graduate students includes the opportunity to attend and participate in a number of special events and lectureships. Although these opportunities are not formally required by the program of study, students are strongly encouraged to attend and participate in these events.

The MSc (Med) program involves courses and a thesis and can be completed in two years of full-time study.

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The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents.

Degree Information

The programme provides a thorough grounding in modern approaches to the understanding of the genetics of disease alongside the cutting-edge research methods and techniques used to advance our understanding of development of disease. Core modules provide a broad coverage of the genetics of disease, research skills and social aspects, whilst specialised streams in Inherited Diseases, Pharmacogenetics and Computational Genomics, in which students can qualify, and the research project allow more in-depth analysis in areas of genetics.

Students undertake modules to the value of 180 credits.

The programme consists of four core modules (60 credits) and two specialist modules (30 credits) and a research project culminating in a dissertation (90 credits).

A Postgraduate Diploma consisting of six modules (four core modules in term one and two modules within the selected stream in term two) is offered, full-time nine months.

A Postgraduate Certificate consisting of four core modules in term one (60 credits) is offered, full-time three months.

Core Modules
- Advanced Human Genetics: Research Principles
- Human Genetics in Context
- Core Skills
- Basic Statistics for Medical Sciences

Specialist modules
In term two you will take specialist modules depending on the specialist stream you select: Inherited Disease (A); Pharmacogenetics (B); Computational Genomics (C).
- Applications in Human Genetics (A)
- Either Genetics of Cardiovascular Disease or Genetics of Neurological Disease (A)
- Clinical Applications of Pharmacogenetic Tests (B)
- Anti-Cancer Personalised Medicine or Pharmacogenomics, Adverse Drug Reactions and Biomarkers (B)
- Applications in Human Genetics (C)
- Statistics for Interpreting Genetic Data (C)

Dissertation/report
Students undertake an original research project investigating topical questions in genetics and genetics of human disease which culminates in a dissertation of 12,000 to 14,000 words and an oral presentation.

Teaching and learning
Students develop their knowledge and understanding of genetics of human diseases through a combination of lectures, seminars, tutorials, presentations and journal clubs. Taught modules are assessed by unseen written examination and/or, written reports, oral presentations and coursework. The research project is assessed by the dissertation and oral presentation.

Careers

Advanced training in genetic techniques including bioinformatic and statistical approaches positions graduates well for PhD studentships in laboratories using genetic techniques to examine diseases such as heart disease, cancer and neurological disorders. Another large group will seek research jobs in the pharmaceutical industry, or jobs related to genetics in healthcare organisations.

Employability
The MSc in Genetics of Human Disease facilitates acquisition of knowledge and skills relevant to a career in research in many different biomedical disciplines. About half of our graduates enter a research career by undertaking and completing PhDs and working as research associates/scientists in academia. Some of our graduates go on to jobs in the pharmaceutical industry, while others enter careers with clinical genetic diagnosis services, particularly in molecular genetics, in healthcare organisations and hospitals around the world. Those graduates with a prior medical training often utilise their new skills as clinical geneticists.

Why study this degree at UCL?

UCL is in a unique position to offer both the basic science and application of modern genetics to improve human health. The programme is a cross-faculty initiative with teaching from across the School of Life and Medical Sciences (SLMS) at UCL.

Students will be based at the UCL Genetics Institute (UGI), a world-leading centre which develops and applies biostatistical and bioinformatic approaches to human and population genetics. Opportunities to conduct laboratory or computational-based research projects are available in the laboratories of world-leading geneticists affiliated to the UGI.

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The increasing impact of genetics in healthcare and the development of newer sophisticated technologies requires contributions from research scientists, clinical laboratory scientists and clinicians to investigate the causes of, and therefore permit optimal management for, diseases for which alterations in the genome, either at the DNA sequence level or epigenetic level, play a significant role. Collaboration between staff from the University of Glasgow and the NHS West of Scotland Genetics Service enables the MSc in Medical Genetics and Genomics to provide a state-of-the-art view of the application of modern genetic and genomic technologies in medical genetics research and diagnostics, and in delivery of a high quality genetics service to patients, as well as in design of targeted therapies.

Why this programme

◾This is a fully up-to-date Medical Genetics degree delivered by dedicated, multi-award-winning teaching and clinical staff of the University, with considerable input from hospital-based Regional Genetics Service clinicians and clinical scientists.
◾The full spectrum of genetic services is represented, from patient and family counselling to diagnostic testing of individuals and screening of entire populations for genetic conditions: eg the NHS prenatal and newborn screening programmes.
◾The MSc Medical Genetics Course is based on the south side of the River Clyde in the brand new (2015) purpose built Teaching & Learning Centre, at the Queen Elizabeth University Hospitals (we are located 4 miles from the main University Campus). The Centre also houses state of the art educational resources, including a purpose built teaching laboratory, computing facilities and a well equipped library. The West of Scotland Genetic Services are also based here at the Queen Elizabeth Campus allowing students to learn directly from NHS staff about the latest developments to this service.
◾The Medical Genetics MSc Teaching Staff have won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering). These awards recognise and reward excellence and good practice in postgraduate education.
◾The close collaboration between university and hospital staff ensures that the Medical Genetics MSc provides a completely up-to-date representation of the practice of medical genetics and you will have the opportunity to observe during clinics and visit the diagnostic laboratories at the new Southern General Hospital laboratory medicine building.
◾The Medical Genetics degree explores the effects of mutations and variants as well as the current techniques used in NHS genetics laboratory diagnostics and recent developments in diagnostics (including microarray analysis and the use of massively parallel [“next-generation”] sequencing).
◾New developments in medical genetics are incorporated into the lectures and interactive teaching sessions very soon after they are presented at international meetings or published, and you will gain hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenesis of DNA sequence variants.
◾You will develop your skills in problem solving, experimental design, evaluation and interpretation of experimental data, literature searches, scientific writing, oral presentations, poster presentations and team working.
◾This MSc programme will lay the academic foundations on which some students may build in pursuing research at PhD level in genetics or related areas of biomedical science or by moving into related careers in diagnostic services.
◾The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.
◾For doctors: The Joint Royal Colleges of Physicians’ Training Board (JRCPTB) in the UK recognises the MSc in Medical Genetics and Genomics (which was established in 1984) as counting for six months of the higher specialist training in Clinical Genetics.
◾The Medical Council of Hong Kong recognises the MSc in Medical Genetics and Genomics from University of Glasgow in it's list of Quotable Qualifications.

Programme structure

Genetic Disease: from the Laboratory to the Clinic

This course is designed in collaboration with the West of Scotland Regional Genetics Service to give students a working knowledge of the principles and practice of Medical Genetics and Genomics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease. The link from genotype to phenotype, will be explored, with consideration of how this knowledge might contribute to new therapeutic approaches.

Case Investigations in Medical Genetics and Genomics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Clinical Genomics

Students will take this course OR Omic Technologies for Biomedical Sciences OR Frontiers in Cancer Science.

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussion the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Omic technologies for the Biomedical Sciences: from Genomics to Metabolomics

Students will take this course OR Clinical Genomics OR Frontiers in Cancer Science.

Visit the website for further information

Career prospects

Research: About half of our graduates enter a research career and most of these graduates undertake and complete PhDs; the MSc in Medical Genetics and Genomics facilitates acquisition of skills relevant to a career in research in many different bio-molecular disciplines.

Diagnostics: Some of our graduates enter careers with clinical genetic diagnostic services, particularly in molecular genetics and cytogenetics.

Clinical genetics: Those of our graduates with a prior medical / nursing training often utilise their new skills in careers as clinical geneticists or genetic counsellors.

Other: Although the focus of teaching is on using the available technologies for the purpose of genetic diagnostics, many of these technologies are used in diverse areas of biomedical science research and in forensic DNA analysis. Some of our numerous graduates, who are now employed in many countries around the world, have entered careers in industry, scientific publishing, education and medicine.

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The science of human genetics has been transformed in the past decade. Following the sequencing of the entire human genome, a wealth of resources is now available to researchers aiming to identify the genetic variants that influence human health. These findings will shed light on the underlying molecular pathology of many diseases that are poorly understood at present, eventually paving the way for novel treatment and prevention strategies. The speed at which these discoveries are being made is accelerating, and it is likely that molecular genetics will soon underpin much of modern medicine.

Career Pathways:
The MSc in Human Molecular Genetics programme is designed to prepare you for a genetics research career, either in human gene function and genetic disease, or molecular approaches to diagnosis and health care biotechnology. It provides a broad grounding in Human Genetics, with emphasis on molecular aspects, to give a solid basis for subsequent academic or industrial research, or for entry to NHS Genetics training. Approximately 40% of our students go on to do a PhD, 40% become research assistants/associates, while others go on to jobs in industry or further studies (bioinformatics/computing medicine). One or two students every year enter the NHS in clinical genetics training posts.

Programme Structure:
You will study the fundamentals of human and molecular genetics, models of inheritance for rare and common/ complex polygenic diseases, cytogenetics, analytical methods in human genetics and genomics, animal models and transgenesis, gene therapy, epigenetics, cancer genetics and an introduction to clinical genetics and genetic counselling services.

There are four weeks of intensive laboratory practical sessions, as well as computer science practicals applied to problems in genetics, genomics and bioinformatics, regular research seminars on site, student seminar and journal presentations, study group activities and a six-month full-time research project in the summer.

The programme is based on an average 20 hours contact time per week. This will vary between 15 hours in most weeks and approximately 40 hours during intensive practicals and projects. Private study time is included within the schedule: you are expected to contribute an additional 10-15 hours private study per week to the course. We do not recommend you try to support yourself by taking a part-time employment whilst studying as your work may suffer.

Assessment:
There are 3 x 3-hour written papers in late February, coursework assessments (poster presentation, analytical methods in genetics, oral presentation), a project report and a viva examination in September.

Programme Location:
The programme is primarily based at Hammersmith Campus in West London although some teaching modules are held at St Mary's Campus and the Northwick Park Campus.

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Translating fundamental biomedical discoveries into applied clinical practice and public health issues

Clinical Biology is the only specialisation in the Netherlands that combines fundamental human biology with clinical studies. It provides you with an extensive biological knowledge, and experience in working with animal and patient samples. In this way you’ll be trained to bridge the gap between early biomedical research results and clinical practice.

This wouldn’t be possible within the walls of the Faculty of Science. That’s why there’s an extensive collaboration between the Faculty of Science and the Radboud university medical center in the field of Clinical Biology. You’ll get the best of both worlds: a thorough background in for example molecular oncology, human genetics, physiology and metabolism as well as a clinical view on diseases. This is an excellent background for a medical researcher or a job at the interface of science and society, such as a consultant, policy officer or communications advisor in the area of food or health.

See the website http://www.ru.nl/masters/clinicalbiology

Why study Clinical Biology at Radboud University?

- It is the only programme in the Netherlands that bridges the gap between fundamental biomedical research and clinical treatments.
- You’ll get the opportunity to work together with researchers from the Radboud university medical center.
- Radboud biologists and clinicians stand out in the fields of animal and human physiology, human genetics and disease, and molecular and cellular clinical studies.
- Clinical Biology offers internships at multiple related research institutes, such as the Radboud Institute for Molecular Life Sciences (RIMLS), the Radboud Institute for Health Sciences (RIHS) and the Donders Institute for Brain, Cognition and Behaviour (DI).
- There are various opportunities to do an internship abroad thanks to our wide network of cooperating research groups.

Career prospects

After graduation, our students quickly take up positions as researchers in government departments, research organisations and medical or pharmaceutical companies. However, many of our graduates also apply their academic background to societal issues, for example as a communications or policy officer. In general, clinical biologists end up as a:
- Researcher in a hospital or a university
- Researcher in a company, either a large or a start-up company
- Supervisor of clinical trials
- Consultant in the area of health or food
- Policy officer in the area of health or food
- Communications officer at a hospital or a governmental organisation, like RIVM
- Teacher in biology or medical biology

PhD positions at Radboud University
Each year, Radboudumc offers PhD positions in this field of research. Of course, many graduates also apply for a PhD position at related departments in the Netherlands, or abroad.

Our approach to this field

- From human biology to clinical treatment
Clinical Biology at Radboud University connects fundamental biological research to clinical treatments. The courses will provide you with a solid background in human physiology and molecular biology, which you’ll apply in developing clinically-oriented research questions. As there’s an extensive collaboration between the Faculty of Science and the Radboud university medical center, you’ll become familiar with both perspectives.

- Biomaterials
In your internships you’ll work with biomaterials, such as patient and animal samples. This means you’ll apply your biological knowledge to real-life situations. Clinical biologists do not work with patients or clinical treatments directly.

- Three focus areas
This Master’s specialisation focuses on three main topics:

- Molecular Mechanisms of Novel Therapeutics
Which molecular mechanisms lead to cancer? And how can these be translated into clinical practice? These are key questions in the specialisation in Clinical Biology. For example, we’ll dive into the functioning of epigenetics (heritable modifications of chromosomes without altering the nucleotide sequence), transcription factors, tumour suppressors and immunotherapy.

- Human Genetics and Physiology
This part is about how new developments and discoveries in genetic and molecular fields can help individual patients to improve functionality, independence and quality of life. You’ll study genetic pathways and the functionality of individual organs, organ systems, regulatory mechanisms, and individuals as a whole, in an integrative way.

- Metabolism, Transport and Mobility
The energy balance in our body is one of the most important factors in health and disease. We’ll teach you how energy and metabolites are integrated into the larger cellular networks for metabolism, transport and motility.

See the website http://www.ru.nl/masters/clinicalbiology

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The increasing impact of genetics in healthcare and the development of newer sophisticated technologies requires close collaboration between research scientists, clinical laboratory scientists and clinicians to deliver a high quality service to patients. The Clinical Genetics MSc has a specific focus on delivery of the clinical service to patients including risk analysis and application of modern genetic and genomic technologies in medical genetics research and in diagnostics and population screening.

● This is a fully up-to-date Clinical Genetics degree delivered by dedicated, multi-award-winning teaching and clinical staff of the University, with considerable input from hospital-based Regional Genetics Service clinicians and clinical scientists.
● The full spectrum of genetic services is represented, from patient and family counselling to diagnostic testing of individuals and screening of entire populations for genetic conditions: eg the NHS prenatal and newborn screening programmes.
● The Clinical Genetics MSc Teaching Staff won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering). These awards recognise and reward excellence and good practice in postgraduate education.
● The close collaboration between university and hospital staff ensures that the Clinical Genetics MSc provides a completely up-to-date representation of the practice of medical genetics and you will have the opportunity to observe during clinics at the new Queen Elizabeth University Hospital laboratory medicine building.
● The Clinical Genetics degree explores the effects of mutations and variants as well as the theoretically basis of current techniques used in NHS genetics laboratory diagnostics and recent developments in diagnostics (including microarray analysis and the use of massively parallel [“next-generation”] sequencing).
● New developments in genetics are incorporated into the lectures and interactive teaching sessions very soon after they are presented at international meetings or published, and you will gain hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenesis of DNA sequence variants.
● You will develop your skills in problem solving, evaluation and interpretation of genetic data, literature searches, scientific writing, oral presentations, poster presentations and team working.
● This MSc programme will lay the academic foundations on which some students with prior MBChB or MBBS may build in pursuing careers in Clinical Genetics.
● The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.
● For doctors: The Joint Royal Colleges of Physicians’ Training Board (JRCPTB) in the UK recognises the MSc in Clinical Genetics (which was established in 1984) as counting for six months of the higher specialist training in Clinical Genetics.

Programme Structure

Genetic Disease and Clinical Practice

This course is designed in collaboration with the West of Scotland Regional Genetics Service to give students a working knowledge of the principles and practice of Clinical Genetics and Genomics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease. The link from genotype to phenotype, will be explored, with consideration of how this knowledge might contribute to new therapeutic approaches.

Distress or Disorder: Reactions to a medical diagnosis

This course outlines the process of psychosocial adjustment to a diagnosis or test result allowing participants to establish if and when a distress reaction develops into an adjustment disorder. The implications of diagnosis are explored and evidence considered allowing informed decisions about appropriate referrals to other agencies.

Patient Empowerment: Supporting decisions relating to new diagnoses

This course reflects on evidence and experience to explore the psychological and social impact of a diagnosis, or illness, and provides strategies to support resilience and coping in patients. Factors related to lived experience, personal beliefs and values, culture, adjustment processes, decision-making, misconceptions, secrecy and guilt are considered to equip participants in the promotion of patient-centred care.

Effective listening and communication skills

With a focus on experiential learning and student led study, this course outlines the role of counselling skills to facilitate adjustment and to allow an individual to come to terms with change in a safe way to minimise impact. The focus will be on the theory supporting counselling, developing key listening and communication skills and on establishing reflective practice.

Case Investigations in Medical Genetics and Genomics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Clinical Genomics

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussion the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Disease Screening in Populations

This course will cover the rationale for, and requirements of, population screening programmes to detect individuals at high risk of particular conditions, who can then be offered diagnostic investigations. Students will work in groups to investigate and report on, a screening programme of their choice from any country.

Dissertation

The course will provide students with the opportunity to carry out an independent investigative project in the field of Medical Genetics and Genomics.

Teaching and Learning Methods

A variety of methods are used, including problem-based learning, case-based learning, lectures and tutorials. These are supplemented by a wide range of course-specific electronic resources for additional learning and self-assessment. As a result, you will develop a wide range of skills relevant to careers in clinical genetics. These skills include team-working and data interpretation. You will use the primary scientific literature as an information resource, although textbooks such as our own Essential Medical Genetics will also be useful. You will have the options of: attending genetic counselling clinics and gaining hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenicity of DNA sequence variants.

Visit the website for more information http://www.gla.ac.uk/postgraduate/taught/clinicalgenetics/#/programmestructure

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The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Research areas include: genetic medicine, developmental genetics, neuromuscular and neurological genetics, mitochondrial genetics and cardiovascular genetics.

As a research postgraduate in the Institute of Genetic Medicine you will be a member of our thriving research community. The Institute is located in Newcastle’s Life Science Centre. You will work alongside a number of research, clinical and educational organisations, including the Northern Genetics Service.

We offer supervision for MPhil in the following research areas:

Cancer genetics and genome instability

Our research includes:
-A major clinical trial for chemoprevention of colon cancer
-Genetic analyses of neuroblastoma susceptibility
-Research into Wilms Tumour (a childhood kidney cancer)
-Studies on cell cycle regulation and genome instability

Cardiovascular genetics and development

We use techniques of high-throughput genetic analyses to identify mechanisms where genetic variability between individuals contributes to the risk of developing cardiovascular disease. We also use mouse, zebrafish and stem cell models to understand the ways in which particular gene families' genetic and environmental factors are involved in the normal and abnormal development of the heart and blood vessels.

Complex disease and quantitative genetics

We work on large-scale studies into the genetic basis of common diseases with complex genetic causes, for example autoimmune disease, complex cardiovascular traits and renal disorders. We are also developing novel statistical methods and tools for analysing this genetic data.

Developmental genetics

We study genes known (or suspected to be) involved in malformations found in newborn babies. These include genes involved in normal and abnormal development of the face, brain, heart, muscle and kidney system. Our research includes the use of knockout mice and zebrafish as laboratory models.

Gene expression and regulation in normal development and disease

We research how gene expression is controlled during development and misregulated in diseases, including the roles of transcription factors, RNA binding proteins and the signalling pathways that control these. We conduct studies of early human brain development, including gene expression analysis, primary cell culture models, and 3D visualisation and modelling.

Genetics of neurological disorders

Our research includes:
-The identification of genes that in isolation can cause neurological disorders
-Molecular mechanisms and treatment of neurometabolic disease
-Complex genetics of common neurological disorders including Parkinson's disease and Alzheimer's disease
-The genetics of epilepsy

Kidney genetics and development

Kidney research focuses on:
-Atypical haemolytic uraemic syndrome (aHUS)
-Vesicoureteric reflux (VUR)
-Cystic renal disease
-Nephrolithiasis to study renal genetics

The discovery that aHUS is a disease of complement dysregulation has led to a specific interest in complement genetics.

Mitochondrial disease

Our research includes:
-Investigation of the role of mitochondria in human disease
-Nuclear-mitochondrial interactions in disease
-The inheritance of mitochondrial DNA heteroplasmy
-Mitochondrial function in stem cells

Neuromuscular genetics

The Neuromuscular Research Group has a series of basic research programmes looking at the function of novel muscle proteins and their roles in pathogenesis. Recently developed translational research programmes are seeking therapeutic targets for various muscle diseases.

Stem cell biology

We research human embryonic stem (ES) cells, germline stem cells and somatic stem cells. ES cell research is aimed at understanding stem cell pluripotency, self-renewal, survival and epigenetic control of differentiation and development. This includes the functional analysis of genes involved in germline stem cell proliferation and differentiation. Somatic stem cell projects include programmes on umbilical cord blood stem cells, haematopoietic progenitors, and limbal stem cells.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.

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Within the Human Molecular Genetics area there is an emphasis on the role of repetitive DNA sequences in health and disease, and in chromosome stability. Research projects include: studies to understand the molecular basis of myotonic dystrophy, the identification of genes involved in human developmental heart disorders; cardiac stem cells; the role of apoptosis in brain tumour development and therapy; artificial chromosomes and chromosome segregation; human genetic diversity; copy number analysis; molecular genetics of muscle disease; mouse models of muscle disorders; and molecular genetic approaches to anthropology and human population genetics.

APPLICATION PROCEDURES

After identifying which Masters you wish to pursue please complete an on-line application form
https://pgapps.nottingham.ac.uk/
Mark clearly on this form your choice of course title, give a brief outline of your proposed research and follow the automated prompts to provide documentation. Once the School has your application and accompanying documents (eg referees reports, transcripts/certificates) your application will be matched to an appropriate academic supervisor and considered for an offer of admission.

COURSE STRUCTURE
The MRes degree course consists of two elements:
160 credits of assessed work. The assessed work will normally be based entirely on a research project and will be the equivalent of around 10 ½ months full-time research AND
20 credits of non-assessed generic training. Credits can be accumulated from any of the courses offered by the Graduate School. http://www.nottingham.ac.uk/gradschool/research-training/index.phtml The generic courses should be chosen by the student in consultation with the supervisor(s).

ASSESSMENT
The research project will normally be assessed by a dissertation of a maximum of 30,000 to 35,000 words, or equivalent as appropriate*. The examiners may if they so wish require the student to attend a viva.
*In consultation with the supervisor it maybe possible for students to elect to do a shorter research project and take a maximum of 40 credits of assessed modules.

The School of Life Sciences will provide each postgraduate research student with a laptop for their exclusive use for the duration of their studies in the School.

SCHOLARSHIPS FOR INTERNATIONAL STUDENTS
http://www.nottingham.ac.uk/studywithus/international-applicants/scholarships-fees-and-finance/scholarships/masters-scholarships.aspx

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Molecular genetics is the study of genes at the molecular level. It focuses on the processes that underlie the expression of the genetic information from the DNA into the functional proteins that execute the genetic programme. Within the School of Life Sciences research in molecular genetics is concentrated in the Human Genetics, Fungal Biology, and Developmental Genetics and Gene Control groups. In the Human Genetics group research in this area includes studies of the molecular basis of myotonic dystrophy and the identification of genes involved in cardiac development; the molecular genetics of muscle disease; mouse models of muscle disorders and molecular genetic approaches to anthropology and human population genetics. In the Fungal Biology group there are studies on the molecular events that determine stress responses during polarised growth, protein folding and secretion in yeasts and filamentous fungi; the molecular and cellular effects of stress on yeast cells and the genetic mechanisms that control sex in fungi. The Developmental Genetics and Gene Control group focuses on the mechanisms of eukaryotic gene expression and the genetics of vertebrate embryonic development. Developmental studies are focussed largely upon the mechanisms that control stem cell fate. Projects on the control of gene expression address the machinery used by cells to achieve appropriate levels of functional transcripts. These studies include control of transcription and the mechanisms of RNA maturation.

APPLICATION PROCEDURES
After identifying which Masters you wish to pursue please complete an on-line application form
https://pgapps.nottingham.ac.uk/
Mark clearly on this form your choice of course title, give a brief outline of your proposed research and follow the automated prompts to provide documentation. Once the School has your application and accompanying documents (eg referees reports, transcripts/certificates) your application will be matched to an appropriate academic supervisor and considered for an offer of admission.

COURSE STRUCTURE
The MRes degree course consists of two elements:
160 credits of assessed work. The assessed work will normally be based entirely on a research project and will be the equivalent of around 10 ½ months full-time research work. AND
20 credits of non-assessed generic training. Credits can be accumulated from any of the courses offered by the Graduate School. http://www.nottingham.ac.uk/gradschool/research-training/index.phtml The generic courses should be chosen by the student in consultation with the supervisor(s).

ASSESSMENT
The research project will normally be assessed by a dissertation of a maximum of 30,000 to 35,000 words, or equivalent as appropriate*. The examiners may if they so wish require the student to attend a viva.
*In consultation with the supervisor it maybe possible for students to elect to do a shorter research project and take a maximum of 40 credits of assessed modules.

The School of Life Sciences will provide each postgraduate research student with a laptop for their exclusive use for the duration of their studies in the School.

SCHOLARSHIPS FOR INTERNATIONAL STUDENTS
http://www.nottingham.ac.uk/studywithus/international-applicants/scholarships-fees-and-finance/scholarships/masters-scholarships.aspx

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About the course

This MSc gives students excellent postgraduate training, and leads to exciting careers in research, industry, the NHS and other clinical institutions. Many of our graduates have also gone on to study bioscience at PhD level.

You’ll develop an in-depth knowledge of medical and molecular genetics, and receive clinical genetics training to prepare you for a research project in a modern research facility. You’ll have the chance to collaborate with top genetics research laboratories and clinical partners.

This MSc was developed in partnership with the Sheffield Diagnostic Genetics Service (NHS), which is a world-renowned clinical genetics facility. This relationship is unique to this course and gives you the opportunity to be taught by the Director of the Sheffield Diagnostic Genetics Service, Sheffield Children’s Hospital NHS Foundation Trust, 
and their Head of Pharmacogenetics.

Where your masters can take you

Our graduates work in health care, pharmaceuticals, food safety and production, brewing and agrochemicals. Many of our masters students go on to do a PhD then pursue a career in research; others have gained entry to the prestigious NHS Scientist Training Programme (STP).

An international reputation

The 2014 Research Excellence Framework (REF) ranks Sheffield No 1 for biomedical research and in the UK top five for biological sciences generally. We have regular seminars from distinguished experts, and our motivated staff undertake collaborative research ranging from biotechnology to medicine.

Teaching and assessment

Our masters courses give you a solid grounding in experimental science, with personal supervision and tutorials by experienced scientists, based in modern and well-equipped labs, leading on to a research project in which you design and conduct your own research. You will learn cutting edge science from research leaders, and gain practice in reading the scientific literature and writing reports. Assessment is based on a combination of coursework, project work, formal examinations and a dissertation.

Modules

Genome Stability and Genetic Change; Human Genetics I; Human Genetics II; Advanced Research Topics; Laboratory Techniques in Molecular Bioscience; Literature Review; Research Project.

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The MSc in Biomedical Science (Online) is a part-time, distance learning programme designed for students working in a hospital/laboratory setting. The programme comprises 4 structured stand-alone online learning modules from the Biomed Online Learning Programme and a workplace based project.

Students apply for the MSc programme after completing four online modules and once they have their project idea approved. The project is conceived by the individual but carefully scrutinised by a suitably qualified team drawn from the university and workplace before implementation and normally conducted in the workplace under guidance of a suitably qualified practitioner, and the whole overseen by an academic supervisor from the university. This helps to ground the programme with relevance to workplace requirements.

The online learning modules each offer Continuing Professional Development credits and each has been designed to be relevant to workplace practice. Students are given a free choice of modules, currently sixteen, so that they can tailor their studies to the needs of their workplace and their individual areas of interest. The online modules run for two intakes each year - October to January, and April to July.

The programme is not intended to be an 'end point' in an individual's personal development, but as a stage from which they can continue career development and increase their potential to make greater contributions to overall employer needs.

The Biomed Online Learning programme is managed by a consortium of NHS Trusts, Pathology Joint Ventures, Public Health England and the University of Greenwich.

For further Information please contact the Biomed Admin Manager:
E-mail: [email protected]
Phone: 020 8331 9978

The aims of the programme are:

- To provide an appropriate knowledge base in specialised areas of biomedical science, with the intention of building on individuals' skills and knowledge base obtained at undergraduate level or its equivalent and in the workplace

- To provide part of the lifelong learning that plays an essential role in biomedical science generally

- To provide continuing professional development in selected areas within that field of endeavour.

Visit the website http://www2.gre.ac.uk/study/courses/pg/bio/bio

Science - Biosciences

Bioscience in essence is the use of science to explain human physiology and disease and to use the knowledge of science to develop treatments. It is the application of science rather than the study of things for their own sake.

Bioscience degrees are a result of the ever advancing needs of specialist knowledge as new scientific breakthroughs are made. They are partly a product of this specialisation and partly a response to students interested in human-focused study.

What you'll study

Distance learning
- Year 1:
Students are required to choose 60 credits from this list of options.

Lung Disease (30 credits)
Renal Disease (30 credits)
Diagnosis of Breast Cancer (30 credits)
Immunocytochemistry in Diagnostic Cellular Pathology (30 credits)
Clinical Data Interpretation (30 credits)
Implementing Advanced Quality Management (30 credits)
Governance and Risk Management (30 credits)
Robotics and Automation (in Laboratory Science) (30 credits)
Chromatography-Mass Spectrometry Analysis in Healthcare Settings (30 credits)
Analysis of Nucleic Acids (30 credits)
Advanced Human Genetics (30 credits)
Management of Healthcare Associated Infection (30 credits)
Quality Systems Management (30 credits)
Point of Care Testing (30 credits)
Blood Transfusion (30 credits)
Managing Learning and Development in Healthcare (30 credits)

-Year 2:
Students are required to choose 60 credits from this list of options.

Lung Disease (30 credits)
Renal Disease (30 credits)
Diagnosis of Breast Cancer (30 credits)
Immunocytochemistry in Diagnostic Cellular Pathology (30 credits)
Clinical Data Interpretation (30 credits)
Implementing Advanced Quality Management (30 credits)
Governance and Risk Management (30 credits)
Robotics and Automation (in Laboratory Science) (30 credits)
Chromatography-Mass Spectrometry Analysis in Healthcare Settings (30 credits)
Analysis of Nucleic Acids (30 credits)
Advanced Human Genetics (30 credits)
Management of Healthcare Associated Infection (30 credits)
Quality Systems Management (30 credits)
Point of Care Testing (30 credits)
Blood Transfusion (30 credits)
Managing Learning and Development in Healthcare (30 credits)

-Year 3:
Students are required to study the following compulsory courses.

Project (MSc Biomedical Sci) (60 credits)

Fees and finance

Your time at university should be enjoyable and rewarding, and it is important that it is not spoilt by unnecessary financial worries. We recommend that you spend time planning your finances, both before coming to university and while you are here. We can offer advice on living costs and budgeting, as well as on awards, allowances and loans.

Find out more about our fees and the support available to you at our:
- Postgraduate finance pages (http://www.gre.ac.uk/finance/pg)
- International students' finance pages (http://www.gre.ac.uk/finance/international)

Assessment

Students are assessed through case study orientated reports, production of posters, presentations, contributions to online discussions, tests, online assessments and a research project.

Career options

The programme is directed mainly towards those working in NHS / healthcare laboratories, with the intention of providing opportunities for professional advancement following registration and for continuing professional development.

Biomed Online Learning Programme is open to national and international students but due to the nature of the project the MSc Programme is only open to students working in a hospital/laboratory setting in the UK.

Find out how to apply here - http://www2.gre.ac.uk/study/apply

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Evolutionary theory has radically altered our understanding of human life. The Human Evolution and Behaviour MSc at UCL is designed to provide students with a solid practical and theoretical grounding in issues relevant to the evolution of humans and non-human primates.

Degree information

Students develop the ability to generate, assess and synthesise empirical evidence and hypotheses related to human evolution and behaviour. They gain subject-specific skills, such as measuring skeletal material, interpreting and generating data related to human ecology, reproduction and genetics, and generating behavioural data of humans and non-human primates through observation.

Students undertake modules to the value of 180 credits. The programme consists of one core module (15 credits), five optional modules (75 credits), and a research dissertation (90 credits).

Core modules - students choose two of the first three modules in the list below. Postgraduate Methods/Statistics I is compulsory for all students.
-Human Behavioural Ecology
-Primate Socioecology
-Palaeoanthropology
-Postgraduate Methods/Statistics 1 (term one)*

Optional modules - students choose three of the following optional modules:
-Advanced Human Evolution
-Anthropological and Archaeological Genetics
-Archaeology of Hunter-Gatherers
-Palaeoanthropology
-Evolution of the Human Brain
-Cognition and Language
-Evolution of the Human Brain and Behaviour
-Primate Evolution
-Variation and Evolution of the Human Skull
-Ethnographic and Documentary Filmmaking

Dissertation/report
All MSc students undertake an independent research project which culminates in a 15,000-word dissertation.

Teaching and learning
The programme is delivered through a combination of lectures including weekly two-hour departmental seminars, and occasional attendance at non-departmental seminars. Assessment is through take-home examination, essays, lab-books, practical tests, and presentation. The dissertation is assessed by a project presentation and the thesis.

Careers

Many graduates are successful in entering fully funded doctoral programmes based on their training and achievements on the programme. Our graduates also go not o work in the media (TV, radio , publishing), in NGOs (community development, nature conservation), government organisations (national statistics, health programmes), in zoos and museums (overseeing collections, co-ordination research), or become school teachers. Moreover, numerous alumni have become notable academics in their own right, teaching as permanent staff in universities across the globe.

Employability
Graduates of the programme will be trained in the fundamentals of scientific inquiry including hypothesis generation, data collection and statistical analysis, data synthesis and reporting of results. Additionally, they acquire advanced training in computer-based quantitative methods, presentation techniques, and the public understanding of science. Students will also gain skills specific to their dissertation research that can include behavioural observation techniques, field data collection, computer modelling, and advanced shape analysis.

Why study this degree at UCL?

UCL Anthropology was the first in the UK to integrate biological and social anthropology with material culture into a broad-based conception of the discipline. It is one of the largest anthropology departments in the UK in terms of both staff and research student numbers, offering an exceptional breadth of expertise. Our excellent results in 2008 Research Assessment Exercise and 2014 Research Excellence Framework identify us as the leading broad-based anthropology department in the UK. Students are encouraged to take full advantage of the wider anthropological community in London and the department's strong links with European universities and international institutions.

Our excellent results in the 2001 and 2008 Research Assessment Exercises show that we are the top broad-based anthropology department in the UK.

Students are encouraged to take full advantage of the wider anthropological community in London and the department's strong links with European universities and international institutions.

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The MSc in Nutrition and Genetics aims to educate students in molecular biology principles that explain the interactions between human DNA and nutrition.

Why study Nutrition and Genetics?

The degree provides students with the knowledge and understanding of the progress, advantages and limitations of personalised nutrition. Finally, the programme will provide students with the necessary practical skills associated with molecular nutrition techniques.

NHS England states that “the shift to personalised medicine is already underway” and the NHS National Genetics and Genomics Education Centre has developed specific learning outcomes that need to be achieved by currently practising and future dietitians.

Freelance dietitians and nutritionists already feel the need to include elements of genetics and personalised nutrition in their consultations. An extensive market analysis on consumer trends (DataMonitor) showed that one of the main food-consumer “mega” trends is that people of all ages are more proactively addressing their health in a more personalised manner. The UK is one of the leading countries in consumer rates who consider the idea of using genetics in nutritional advice.

Why St Mary's?

St Mary’s University, Twickenham is the first and only university in the UK that offers a degree in Nutrition and Genetics. Teaching staff at St Mary’s have great experience teaching Nutrition and they also conduct research in the field of Nutrition and Genetics. St Mary’s University has been ranked as the top London university for student experience and we are proud of the excellent tutoring support we offer. The specific programme offers the opportunity for students to carry out their Research Project at the University of Navarra (Pamplona, Spain) as part of the Erasmus exchange programme.

Course Content

What you will study
-Principles of molecular biology
-Genetics in health and disease
-Nutrient-gene interactions
-Genetics and personalised nutrition
-Applied personalised nutrition
-Genetic tests in nutrition
-Research Project

Please note: All information is correct at the time of publication. However, course content is regularly updated and this may result in some changes, which will be communicated to students before their programme begins.

Career Prospects

Graduates of the MSc in Nutrition and Genetics will have gained an expertise in incorporating elements of genetic profiling in nutritional and dietary assessments and regimes. Also, graduates of this programme will be in a unique position to work for (or with) companies that offer genotyping services; such companies are becoming increasingly popular, creating the need for such expertise.

Finally, the specific degree is the ideal platform for a career in research considering that graduates will be in the advantageous position to combine two distinct scientific disciplines (Nutrition and Genetics).

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