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The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents. Read more
The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents.

Degree Information

The programme provides a thorough grounding in modern approaches to the understanding of the genetics of disease alongside the cutting-edge research methods and techniques used to advance our understanding of development of disease. Core modules provide a broad coverage of the genetics of disease, research skills and social aspects, whilst specialised streams in Inherited Diseases, Pharmacogenetics and Computational Genomics, in which students can qualify, and the research project allow more in-depth analysis in areas of genetics.

Students undertake modules to the value of 180 credits.

The programme consists of four core modules (60 credits) and two specialist modules (30 credits) and a research project culminating in a dissertation (90 credits).

A Postgraduate Diploma consisting of six modules (four core modules in term one and two modules within the selected stream in term two) is offered, full-time nine months.

A Postgraduate Certificate consisting of four core modules in term one (60 credits) is offered, full-time three months.

Core Modules
- Advanced Human Genetics: Research Principles
- Human Genetics in Context
- Core Skills
- Basic Statistics for Medical Sciences

Specialist modules
In term two you will take specialist modules depending on the specialist stream you select: Inherited Disease (A); Pharmacogenetics (B); Computational Genomics (C).
- Applications in Human Genetics (A)
- Either Genetics of Cardiovascular Disease or Genetics of Neurological Disease (A)
- Clinical Applications of Pharmacogenetic Tests (B)
- Anti-Cancer Personalised Medicine or Pharmacogenomics, Adverse Drug Reactions and Biomarkers (B)
- Applications in Human Genetics (C)
- Statistics for Interpreting Genetic Data (C)

Dissertation/report
Students undertake an original research project investigating topical questions in genetics and genetics of human disease which culminates in a dissertation of 12,000 to 14,000 words and an oral presentation.

Teaching and learning
Students develop their knowledge and understanding of genetics of human diseases through a combination of lectures, seminars, tutorials, presentations and journal clubs. Taught modules are assessed by unseen written examination and/or, written reports, oral presentations and coursework. The research project is assessed by the dissertation and oral presentation.

Careers

Advanced training in genetic techniques including bioinformatic and statistical approaches positions graduates well for PhD studentships in laboratories using genetic techniques to examine diseases such as heart disease, cancer and neurological disorders. Another large group will seek research jobs in the pharmaceutical industry, or jobs related to genetics in healthcare organisations.

Employability
The MSc in Genetics of Human Disease facilitates acquisition of knowledge and skills relevant to a career in research in many different biomedical disciplines. About half of our graduates enter a research career by undertaking and completing PhDs and working as research associates/scientists in academia. Some of our graduates go on to jobs in the pharmaceutical industry, while others enter careers with clinical genetic diagnosis services, particularly in molecular genetics, in healthcare organisations and hospitals around the world. Those graduates with a prior medical training often utilise their new skills as clinical geneticists.

Why study this degree at UCL?

UCL is in a unique position to offer both the basic science and application of modern genetics to improve human health. The programme is a cross-faculty initiative with teaching from across the School of Life and Medical Sciences (SLMS) at UCL.

Students will be based at the UCL Genetics Institute (UGI), a world-leading centre which develops and applies biostatistical and bioinformatic approaches to human and population genetics. Opportunities to conduct laboratory or computational-based research projects are available in the laboratories of world-leading geneticists affiliated to the UGI.

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This course blends theory and practice to help you develop the skills required for a career in molecular and cellular biology. Our teaching focuses on integrated mammalian biology and animal models of human disease, drawing on our pioneering biomedical research. Read more

About the course

This course blends theory and practice to help you develop the skills required for a career in molecular and cellular biology. Our teaching focuses on integrated mammalian biology and animal models of human disease, drawing on our pioneering biomedical research.

Where your masters can take you

Graduates with skills in stem cell and regenerative medicine are in demand. Your degree will prepare you for a career in research in academia or industry, or in a clinical-related field. Our graduates are working all over the world – from the UK to China, India and the USA – and over half go on to doctoral study.

Learn from the experts

The 2014 Research Excellence Framework (REF) rates us No 1 in the UK for research in this field. Our international reputation attracts highly motivated staff and students. Sheffield is a vibrant place to take a masters based on pioneering research.

Regular seminars from distinguished international experts help you to connect your studies to the latest developments. We’re also part of collaborative research groups for developmental biology, cell biology, physiology, pharmacology, neuroscience, models of human disease, stem cell science and regenerative medicine.

Our three research centres focus on translating laboratory research to the clinical environment: Bateson Centre, the Centre for Stem Cell Biology, and the Centre for Membrane Interactions and Dynamics.

Leaders in our field

We have a long track record of groundbreaking discoveries. These include breakthroughs in human stem cells for hearing repair, and the generation of animal models for Parkinson’s disease, schizophrenia, muscular dystrophies and their use for therapeutic studies.

Labs and equipment

We have purpose-built facilities for drosophila, zebrafish, chick and mouse genetics and for molecular physiology. Other facilities provide all the tools you’ll need to examine and analyse a range of cellular structures. We have an electron and a light microscopy centre, a PCR robotics facility, a flow cytometry unit and an RNAi screening facility.

Teaching and assessment

There are lectures, practical classes, tutorials and seminars. In small group teaching classes you’ll discuss, debate and present on scientific and ethical topics. Laboratory placements within the department provide you with one-to-one attention, training and support to do your individual research project. Assessment is by formal examinations, coursework assignments, debates, poster presentations and a dissertation.

Our teaching covers ethics, practical scientific skills and an overview of the current literature. You’ll also develop useful career skills such as presentation, communication and time management.

Core modules

Literature Review; Practical Research Project; Analysis of Current Science; Ethics and Public Understanding.

Examples of optional modules

Integrated Mammalian Biology; Practical Cell Biology; Practical Developmental Genetics; Cancer Biology; Modelling Human Diseases; Epithelia in Health and Disease.

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The MRes in Biomedical Research - Molecular Basis of Human Disease provides training and teaching in multidisciplinary approach to understand disease mechanisms. Read more
The MRes in Biomedical Research - Molecular Basis of Human Disease provides training and teaching in multidisciplinary approach to understand disease mechanisms. The emphasis of the MRes is on a broad range of training from structural and chemical biology to clinical applications in order to gain knowledge across the biological scales from atoms, molecules to whole cell/organisms on pressing human diseases such as cancer, cardiovascular and pulmonary diseases, metabolic and cellular disease as well as pathogen infection and resistance.

Like the other MRes streams, this course exposes students to the latest developments in the field through two research projects that are complementary in training, with one focusing on molecular mechanism while the other one on disease pathways and/or clinical applications. This course is further supplemented by lectures, tutorials and seminars.

Students will gain experience in applying technologically advanced approaches to biomedical questions. Individuals who successfully complete the course will have developed the ability to:

-Perform novel laboratory based research and exercise critical scientific thought in the interpretation of results.
-Undertake two research projects in line with the multidisciplinary culture of the Section and Division.
-Demonstrate practical and intellectual dexterity in the research project elements.
-Develop an appreciation of cutting edge technologies addressing molecular mechanisms and current understanding of key diseases pathways and mechanisms.
-Be able to interpret and present scientific data
-Be able to interrogate relevant scientific literature and develop research plans.
-Be able to write a grant application, through the taught grant-writing exercise common to all MRes streams.
-Be able to write and defend research reports through writing, poster presentations and seminars.
-Exercise a range of transferable skills by taking a minimum number of short courses taught through the Graduate School.

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The need to develop new strategies to combat diseases remains a major global challenge. Read more
The need to develop new strategies to combat diseases remains a major global challenge. This programme provides advanced training in the mechanisms underpinning a spectrum of infectious and non-infectious diseases, including viral, bacterial and parasitic infections, cancer, neurodegeneration, cardiovascular disease and chromosomal abnormalities. You’ll also explore current and emerging diagnostic and treatment strategies.

You’ll learn about the latest molecular, genetic and cellular approaches being used to understand, diagnose and treat human disease, including traditional methods such as polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA), and novel methods involving genome and proteome analysis. You’ll have the opportunity to investigate the role of the immune system in the response to infection and disease, covering topics such as innate and adaptive immunity, allergy and immune evasion.

You’ll study in a faculty ranked 6th in the UK for its research impact in the recent Research Excellence Framework (REF 2014), and you’ll graduate with the solid base of scientific knowledge and specialist skills valued by employers.

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Surrey’s superb facilities and longstanding reputation for excellence in this field ensure that this postgraduate degree will prepare you for a successful career in nutrition. Read more
Surrey’s superb facilities and longstanding reputation for excellence in this field ensure that this postgraduate degree will prepare you for a successful career in nutrition. As a Human Nutrition student you will be taught by lecturers who are active researchers and are internationally renowned for their expertise in numerous areas.

PROGRAMME OVERVIEW

Our MSc Human Nutrition programme will develop your scientific research skills to an advanced level and fuel your interest in this fascinating and vital discipline.

You will develop a deep understanding of current issues in the field of human nutrition – all taught elements emphasise the evidence-based links between diet, health and disease, and are underpinned by a full appreciation for the nutritional mechanisms involved.

Our excellent links with industry will help you to pursue a successful and rewarding career. The programme also forms an excellent foundation for those who wish to pursue further education via a PhD or research post in industry following graduation.

MSc students may apply for Associate Nutritionist status on the UK Voluntary Register of Nutritionists.

PROGRAMME STRUCTURE

This programme is studied full-time over one academic year. It consists of eight taught modules and an original research project. The following modules are indicative, reflecting the information available at the time of publication. Please note that not all modules described are compulsory and may be subject to teaching availability and/or student demand.
-Fundamentals of Nutrition
-Nutrition Evaluation and Assessment
-Metabolic Nutrition
-Research Nutrition
-International and Public Health Nutrition
-Metabolic Nutrition
-Sports and Exercise Nutrition
-Clinical Nutrition
-Original Research Project

WHO IS THIS PROGRAMME FOR?

Our MSc programme caters for the following applicants:
-Surrey biosciences graduates wishing for an opportunity to convert to postgraduate study within Surrey
-Home/EU nutrition graduates from other institutions wishing to further their nutrition training via taught postgraduate study
-Overseas graduates with equivalent of a nutrition degree from a non-UK institution wishing to obtain a recognised UK postgraduate qualification in nutrition
-Home/EU graduates from a related subject (for example, a biological science including biochemistry and physiology) or registrable qualification (for example, medicine, dentistry) seeking a postgraduate qualification as way of conversion into nutrition

WHY CHOOSE TO STUDY HUMAN NUTRITION?

The University of Surrey has long been regarded as a UK centre of excellence for teaching in nutrition and dietetics through our long-running and successful undergraduate and postgraduate programmes.

Staff within the Department of Nutritional Sciences have an internationally recognised expertise in areas such as diabetes, lipid metabolism, cardiovascular risk, bone health, Vitamin D, selenium and iodine, non-alcoholic fatty liver disease, obesity and energy balance.

As a postgraduate student, you will be taught by a variety of lecturers who are actively researching the topic being covered, or have a wealth of experience in that particular area. You will also have the opportunity to undertake independent research via a project, guided by a dedicated and experienced supervisor. Projects are available across a range of topics representing the strength and depth of the Department and wider Faculty. You will be working alongside staff, PhD students and post-doctoral researchers to ensure that you receive the full research experience.

This will form an excellent foundation for those MSc students wishing to pursue further education via a PhD or research post in industry.

The strong scientific element of our teaching will attract students looking for a programme of high academic quality.

CAREER PROSPECTS

The Department has excellent links with industry, which will help you to pursue a successful career in nutrition.

EDUCATIONAL AIMS OF THE PROGRAMME

-Provide a fundamental understanding of nutritional science, which takes a critical and scholarly approach to relevant theory, practice, literature and latest research findings on the importance of nutrition in diet-health- disease relationships
-Provide new knowledge and understanding of the role of nutrition in both individual and community health
-Discuss the role of diet in the development of disease
-Evaluate the potential, efficacy and scope of nutritional methods in health and disease
-Examine current knowledge of the specific roles of individual macro- and micronutrient deficiencies and imbalances on short- and long-term disease risk
-Explore the concept of optimal nutrition in various special situations
-Develop an understanding of research methodology in the area of Human Nutrition
-Design, undertake, communicate and defend an original research project in nutrition
-Meet the required standards of competency for registered nutritionists as outlined by the Association for Nutrition

PROGRAMME LEARNING OUTCOMES

The programme provides opportunities for students to develop and demonstrate knowledge and understanding, skills, qualities and other attributes in the following areas:

Knowledge and understanding
-The main principles of current human nutrition
-The methods and approaches used for the purposes of nutritional assessment
-Human metabolism in health and in the pathogenesis of disease
-The main principles of public health in relation to diet and nutrition, both nationally and internationally
-Analytical skills to allow interpretation of data or evidence and formulate conclusions
-The application of nutrition principles to sport and exercise
-The influence of nutrition at the molecular/genetic level
-The therapeutic use of nutrition in the management of disease

Intellectual / cognitive skills
-Find and critically evaluate scientific literature and other appropriate sources of material
-Critically evaluate research design and the methods commonly used in nutrition research
-Use acquired knowledge and appropriate skills to make professional judgements
-Design relevant experiments to test formulated hypotheses

Professional practical skills
-Demonstrate competence in commonly used nutrition research methodology
-Gather, analyse and interpret qualitative and quantitative data
-Effectively communicate both orally and in writing
-Learn independently
-Take responsibility for planning and organisation of work both their own and in a team
-Plan and execute an investigation/experiment, act autonomously and demonstrate originality

Key / transferable skills
-Communicate ideas, principles and theories effectively by oral, written and visual means
-Work effectively and independently on a given project or task
-Work effectively in small groups and teams towards a common goal/outcome.
-Apply basic statistical and numerical skills to nutritional data
-Use Information Technology

GLOBAL OPPORTUNITIES

We often give our students the opportunity to acquire international experience during their degrees by taking advantage of our exchange agreements with overseas universities.

In addition to the hugely enjoyable and satisfying experience, time spent abroad adds a distinctive element to your CV.

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This unique research-led masters course provides laboratory training to future scientists in drug screening and gene discovery using the latest automated genomics techniques. Read more

About the course

This unique research-led masters course provides laboratory training to future scientists in drug screening and gene discovery using the latest automated genomics techniques. Students will also gain training in the pharmaceutical industry practices through direct contact with industry leaders from a wide range of companies.

Your research project will be undertaken in conjunction with the internationally renowned Sheffield RNAi Screening Facility, providing you with world-class training and professional skills in the use of pharmaco-genomics. You’ll also benefit from our modern research laboratories and equipment, including purpose-built facilities for drug screening, laboratory automation, cellular assays, imaging and processing.

Where your masters can take you

Graduates with skills in stem cell and regenerative medicine are in demand. Your degree will prepare you for a career in research in academia or industry, or in a clinical-related field. Our graduates are working all over the world – from the UK to China, India and the USA – and over half go on to doctoral study.

Learn from the experts

The 2014 Research Excellence Framework (REF) rates us No 1 in the UK for research in this field. Our international reputation attracts highly motivated staff and students. Sheffield is a vibrant place to take a masters based on pioneering research.

Regular seminars from distinguished international experts help you to connect your studies to the latest developments. We’re also part of collaborative research groups for developmental biology, cell biology, physiology, pharmacology, neuroscience, models of human disease, stem cell science and regenerative medicine.

Our three research centres focus on translating laboratory research to the clinical environment: Bateson Centre, the Centre for Stem Cell Biology, and the Centre for Membrane Interactions and Dynamics.

Leaders in our field

We have a long track record of groundbreaking discoveries. These include breakthroughs in human stem cells for hearing repair, and the generation of animal models for Parkinson’s disease, schizophrenia, muscular dystrophies and their use for therapeutic studies.

Labs and equipment

We have purpose-built facilities for drosophila, zebrafish, chick and mouse genetics and for molecular physiology. Other facilities provide all the tools you’ll need to examine and analyse a range of cellular structures. We have an electron and a light microscopy centre, a PCR robotics facility, a flow cytometry unit and an RNAi screening facility.

Teaching and assessment

There are lectures, practical classes, tutorials and seminars. In small group teaching classes you’ll discuss, debate and present on scientific and ethical topics. Laboratory placements within the department provide you with one-to-one attention, training and support to do your individual research project. Assessment is by formal examinations, coursework assignments, debates, poster presentations and a dissertation.

Our teaching covers ethics, practical scientific skills and an overview of the current literature. You’ll also develop useful career skills such as presentation, communication and time management.

Core modules

Literature Review; Practical Research Project; Analysis of Current Science; Ethics and Public Understanding.

Examples of optional modules

Practical Approaches to Small Molecule and Functional Genomic Screening; 3D Tissue Culture and Genome Editing; Genomic Approaches to Drug Discovery; The Biotech and Pharmaceutical Industry; Modelling Human Disease

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The MSc Molecular Genetics and Diagnostics is suitable for graduates in life sciences, biomedical sciences and allied subjects, as well as people already employed in related fields who wish to improve and update their knowledge and gain valuable experience. Read more
The MSc Molecular Genetics and Diagnostics is suitable for graduates in life sciences, biomedical sciences and allied subjects, as well as people already employed in related fields who wish to improve and update their knowledge and gain valuable experience.

The course is designed to explain the technology, theory and practical approaches of molecular genetic methods to the diagnosis and understanding of human disease.

The course has a start date in September,

The course aims to:

• Provide an advanced course of study in the theoretical and practical aspects of the genetic basis and diagnosis of human disease
• Allow students adequate time to integrate into an active research laboratory where they are able to develop the skills which are essential when considering a career in research
• Train students to carry out critical evaluation of published scientific papers so that they develop the ability to report and interpret results

The academic staff involved with the course are recognised at an international level for their work on the genetic basis of complex diseases, including chronic obstructive pulmonary disease (COPD), Alzheimer's disease and infectious disease caused by clinically relevant microbial pathogens such as Pseudomonas spp., Yersinia spp. and Staphylococcus spp. Colleagues working in Molecular Diagnostics and Clinical Genetics within the NHS also contribute to the teaching on the course.

Key Facts

• The MSc Molecular Genetics and Diagnostics was previously known as the MSc Molecular Diagnostics, and has been running since 2004
• One of the many strengths of the course is the five-month research project that is conducted in the laboratory with a member research staff within the School
• The latest Research Assessment Exercise (RAE) confirmed The University of Nottingham's position as a world class research-led institution. Over 60% of the University's RAE scores identified research as being of a level of international excellence.
• This achievement has helped put Nottingham in the world’s top 1% of Universities internationally according to the latest (2014) QS World University Ranking.
• The peer-reviewed research carried out within the Human Genetics and Molecular and Cellular Bacteriology groups is recognized as being of either international or world-class standard.
• The MSc Molecular Genetics and Diagnostics is coordinated by academic staff within the Molecular and Cellular Bacteriology Research Group, part of the School of Life Sciences. Staff are based either within the Centre for Biomedical Science, a new state of the art research and teaching centre, the adjacent medical school which itself is located in the Queen’s Medical Centre or the Nottingham City Hospital.
• Extensive IT facilities are available across all campuses, including several computer rooms within the medical school.
• The University library service provides access to more than a million books and journals. The Greenfield Medical Library houses a broadly-based collection of biomedical, nursing and healthcare-related books and periodicals and holds current subscriptions to 780 journals, reports and series titles. In addition to the print versions housed in the library, the majority of journals can be accessed electronically.

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Taught in the School of Life Sciences’ state-of-the-art research laboratories and teaching facilities, the MSc in Integrated Physiology in Health and Disease, is the only one of its kind in the UK. Read more
Taught in the School of Life Sciences’ state-of-the-art research laboratories and teaching facilities, the MSc in Integrated Physiology in Health and Disease, is the only one of its kind in the UK.

The course promotes the importance of an integrated and multidisciplinary approach to studying fundamental physiological aspects of human health and disease, including diabetes, obesity and cardiovascular disease, by combining cutting-edge physiological and metabolic methodologies with relevant molecular biology approaches.

Course overview

The course is ideal for:

 students with a background in physiology, biochemistry, biomedical sciences, biology, nutrition, exercise science and other related disciplines
 those with work experience in health-related research
 health and exercise professionals.

It investigates the physiology underlying health and disease – a growing area of interest to academic, private and public sectors – and aims to:

 develop an understanding of the fundamental physiology underpinning the maintenance of health, and the development of disease
 equip students with both generic and specialist skills, including a wide range of laboratory techniques necessary to develop an integrated and translational approach to the study of human metabolism and physiology
 promote the importance of adopting a critical approach to questions of clinical relevance
 provide the necessary foundation for those who wish to pursue advanced research in this area, leading to the degree of PhD.

Course structure

The programme comprises eight modules: six compulsory, one optional, and a laboratory-based research project.

The six compulsory modules are:

 Nutrition in Health and Exercise
 Muscle Physiology and Metabolism
 Metabolism and Nutrition in Disease
 Cardiorenorespiratory Physiology
 Laboratory Techniques
 Statistics and Research Methods

Students choose one of the following two optional modules:

 Medical Pharmacology
 Clinical Neuroscience.

About the School and its staff

The School of Life Sciences, with its unique, high-quality expertise and excellent facilities, is one of the UK’s leaders in research into integrated physiology.

The programme is delivered by staff from the Metabolic Physiology Group. The group has an international research standing in the area of human nutrition, the control and integration of fuel utilisation in health and disease, such as in obesity and diabetes, and the regulation of muscle mass during exercise, inactivity and disease. The group is funded by industry, research charities and research councils.

In recent years, the School has undergone an impressive development and refurbishment programme. Research is conducted in a suite of human physiology laboratories; ex vivo pharmacology laboratories; neuroscience laboratories and a human primary tissue culture laboratory.

These facilities allow integrated metabolic investigations in both patients and healthy individuals to dovetail with relevant modern molecular biology technologies.

Students also benefit from our interactive, multidisciplinary approach to teaching and research alongside colleagues in other schools and clinics based in four regional hospitals: the Queen’s Medical Centre, Nottingham City Hospital, Derbyshire Royal Infirmary and Derby City General Hospital.

Career development

A range of rewarding employment opportunities is open to graduates in this field.

 Experience in the area of integrated and translational physiology is required by an increasing number of research groups in both academia and the private sector.
 The health and exercise sector offers a variety of employment opportunities in rehabilitation, and health and fitness centres.
 The School attracts a number of capacity-building Medical Research Council (MRC) and Biotechnology and Biological Sciences Research Council (BBSRC) PhD studentships each year. On successful completion of the programme, students are considered as serious candidates for these research opportunities.


Assessment

The course requires students to accumulate 180 credits as follows:

 Autumn – three core taught modules (50 credits)
 Spring – five taught modules (80 credits)
 Summer – research project (50 credits).

Assessments are held either at the end of a module or the end of a semester and take the form of an exam, laboratory report or essay.

The research project is assessed through a 15,000-word dissertation and a viva voce.

Funding opportunities

The School offers competitive scholarships specific to the course each year and supports applications for funding to external organisations, including the research councils. For further details, please visit our website.

Related studies

To view related research opportunities with The School of Life Sciences, please visit our website.

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The School of Anatomy, Physiology and Human Biology provides diverse coursework and research opportunities in human biology, including theoretical studies in evolution, human variation and adaptation, human ecology, population and occupational health, and human reproduction. Read more
The School of Anatomy, Physiology and Human Biology provides diverse coursework and research opportunities in human biology, including theoretical studies in evolution, human variation and adaptation, human ecology, population and occupational health, and human reproduction.

Course description, features and facilities

This course is aimed at students who wish to broaden and update their knowledge and expertise in aspects of human biology. Students undertake advanced training in the subject area to developing their investigative skills by participating in projects in different areas in human biology, critical reviews of literature, collection of material (field, experimental or literature) and the processing, analysis and evaluation of data.

The Faculty of Science offers Master's by Coursework bursaries for domestic students and Postgraduate Merit scholarships for international students. Please visit the Faculty of Science website for details.

Structure

Key to availability of units:
S1 = Semester 1; S2 = Semester 2; S3 = summer teaching period; N/A = not available in 2015;
NS = non-standard teaching period; OS = offshore teaching period; * = to be advised

All units have a value of six points unless otherwise stated.

Note: Units that are indicated as N/A may be available in 2016 or 2017.

Take all units (72 points):

Research skills

S1, S2 ANHB5438 Human Biology Project (24 points)
S1, S2 ANHB5446 Human Biology Dissertation Part 1 (18 points)
S1, S2 ANHB5447 Human Biology Dissertation Part 2 (18 points)
S1, S2 APHB4002 Research Design and Analysis
NS, S2 APHB4003 Advanced Experimental Techniques

Take unit(s) to the value of 24 points:

NS ANHB5431 Fundamentals of Sleep Technology
NS ANHB5432 Fundamentals of Sleep Biology
NS APHB5501 Developmental Origins of Health and Disease
NS APHB5502 Human Ecology
NS APHB5503 Neuroendocrinology
NS APHB5505 Advanced Studies in Physiology
N/A APHB5510 Advanced Aesthetic Crossovers of Art and Science
S2 APHB5511 Advanced Art and Life Manipulation
S1 DENT5600 Principles of Dental Public Health
S1 DENT5627 Oral Health Promotion
S2 DENT5628 Management and Financing of Oral Health Services
S2 DENT5629 Research Methods in Dental Public and Primary Health
NS NEUR4010 Modern Research Tools in Neuroscience
N/A NEUR5011 Neurodevelopment and its Disorders
N/A PHYL5510 Physiology of the Auditory System

Career opportunities

This degree is designed for professionals interested in further study who are seeking to familiarise themselves with recent developments in the field, or to enhance their intellectual and research skills.

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Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research. Read more

Understanding the molecular basis of disease

Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research.

Only by dissecting the molecular mechanisms that trigger and advance diseases and dysfunctions can we design effective treatments and medicines. The Research Master's in Molecular Mechanisms of Disease (MMD) offers you an intensive two-year programme that provides you with in-depth knowledge and research experience of disease-related molecular mechanisms. In addition, you will acquire skills such as academic writing and presentation skills and learn how to successfully apply for grants and market yourself.

Passion for molecular biomedical research

As an MMD student you will be part of the unique research community that is found within the Radboud Institute for Molecular Life Sciences (RIMLS). Like you, RIMLS researchers have a strong passion for research. They will assist you throughout the programme with guidance and expertise, supporting you in acquiring knowledge and developing excellent research skills. The RIMLS is one of the research institutes of the Radboud university medical center, so their research is closely linked to the clinic and thus aimed at translating results into treatments for patients. Examples include the translation of insights into the biology of antigen-presenting cells into new immunological cancer therapies and understanding the mutations underlying blindness into the development of gene therapies for patients with inherited blindness.

See the website http://www.ru.nl/masters/mmd

Why study Molecular Mechanisms of Disease at Radboud University?

- You will follow a broad biomedical programme that allows you to specialise in your specific field-of-interest.
- You will have intense daily contact with established researchers.
- You will participate in group-oriented education and be part of a small group of highly motivated national and international students.
- A personal mentor will help you to reflect on your study programme and career perspective.
- You will do two 6-months research internships one of which will be abroad.
- There is a 92% pass rate of MMD students within the two years.
- International MMD students can apply for scholarships from the Radboudumc Study Fund.

Career prospects

There is considerable demand for experts in the molecular biomedical sciences as well as in their application to the development of treatments for diseases such as cancer, autoimmune and inflammatory disorders, and metabolic diseases.

Graduates in MMD are equipped with cutting-edge knowledge of multidisciplinary research in the mechanisms of disease and in state-of-the-art diagnostic methods and technologies. During the programme, you will develop a highly critical, independent approach to problem-solving. You will also acquire the basic management skills needed to lead R&D projects in the biotechnology and pharmaceutical industries.

Most of our graduates will enter an international PhD programme to continue with research in academia or industry.

PhD opportunities

The MSc Molecular Mechanisms of Disease aims to provide all skills and knowledge necessary to rapidly enter an international PhD programme. In the Netherlands and many places in Europe, it is impossible to start a PhD programme directly after obtaining a Bachelor's degree. This research Master’s programme seriously increases your chances for obtaining an excellent PhD training position by giving you a mature perspective and a broad range of experimental approaches. In fact, over 90% of our graduates has started a (funded) PhD project.

The Radboud Institute for Molecular Life Sciences (RIMLS) recruits about fifty PhD students a year. MMD graduates are excellent candidates for these positions. Furthermore, the Radboud university medical centre offers the opportunity for its research-oriented Master's students to write their own research project. The best candidates are awarded a fully funded four-year PhD studentship at the department of their choice.

Our approach to this field

The molecular regulation of cellular processes is crucial for human development, and maintenance of health throughout life. It's evident that cellular malfunction is the cause of common multi-factorial diseases such as diabetes, immune and inflammatory disorders, renal disease, cardiovascular, metabolic and neurodegenerative diseases as well as obesity and cancer.

The Radboud Institute for Molecular Life Sciences (RIMLS) Graduate School plays a key role in developing new therapies for the fight against such diseases. RIMLS aims to improve diagnostics and develop new treatments by generating basic knowledge in the molecular biomedical life sciences and translating it into clinical application and experimental research in patients.

The RIMLS – which is part of Radboud university medical center – offers an exclusive Master's programme in Molecular Mechanisms of Disease. Top researchers and clinicians teach the programme.

Key themes

The MMD programme is organised along three major educational themes which reflect the main research areas present in the RIMLS and which each include both a fundamental and a disease-related aspect:
- Theme 1 Infection, Immunity and Regenerative Medicine / Immunity-related Disorders and Immunotherapy
- Theme 2 Metabolism, Transport and Motion / Metabolic Disorders
- Theme 3 Cell Growth and Differentiation / Developmental Disorders and Malignancies

See the website http://www.ru.nl/masters/mmd

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The science of human genetics has been transformed in the past decade. Following the sequencing of the entire human genome, a wealth of resources is now available to researchers aiming to identify the genetic variants that influence human health. Read more
The science of human genetics has been transformed in the past decade. Following the sequencing of the entire human genome, a wealth of resources is now available to researchers aiming to identify the genetic variants that influence human health. These findings will shed light on the underlying molecular pathology of many diseases that are poorly understood at present, eventually paving the way for novel treatment and prevention strategies. The speed at which these discoveries are being made is accelerating, and it is likely that molecular genetics will soon underpin much of modern medicine.

Career Pathways:
The MSc in Human Molecular Genetics programme is designed to prepare you for a genetics research career, either in human gene function and genetic disease, or molecular approaches to diagnosis and health care biotechnology. It provides a broad grounding in Human Genetics, with emphasis on molecular aspects, to give a solid basis for subsequent academic or industrial research, or for entry to NHS Genetics training. Approximately 40% of our students go on to do a PhD, 40% become research assistants/associates, while others go on to jobs in industry or further studies (bioinformatics/computing medicine). One or two students every year enter the NHS in clinical genetics training posts.

Programme Structure:
You will study the fundamentals of human and molecular genetics, models of inheritance for rare and common/ complex polygenic diseases, cytogenetics, analytical methods in human genetics and genomics, animal models and transgenesis, gene therapy, epigenetics, cancer genetics and an introduction to clinical genetics and genetic counselling services.

There are four weeks of intensive laboratory practical sessions, as well as computer science practicals applied to problems in genetics, genomics and bioinformatics, regular research seminars on site, student seminar and journal presentations, study group activities and a six-month full-time research project in the summer.

The programme is based on an average 20 hours contact time per week. This will vary between 15 hours in most weeks and approximately 40 hours during intensive practicals and projects. Private study time is included within the schedule: you are expected to contribute an additional 10-15 hours private study per week to the course. We do not recommend you try to support yourself by taking a part-time employment whilst studying as your work may suffer.

Assessment:
There are 3 x 3-hour written papers in late February, coursework assessments (poster presentation, analytical methods in genetics, oral presentation), a project report and a viva examination in September.

Programme Location:
The programme is primarily based at Hammersmith Campus in West London although some teaching modules are held at St Mary's Campus and the Northwick Park Campus.

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This course combines theoretical and practical training in biology and control of disease vectors and the human pathogens they transmit. Read more
This course combines theoretical and practical training in biology and control of disease vectors and the human pathogens they transmit. Students will gain specialised skills in the molecular biology of infectious diseases, and will cover all aspects of major vector-borne diseases. The course also offers a thorough grounding in the systematics of medically important arthropods, processes regulating vector populations, and the biology of vector–parasite and vector–vertebrate interactions.

Graduates enter operational control programmes, applied basic research and academic fields. Students benefit from close interaction with staff who have extensive international expertise.

The James Busvine Memorial Medal and Prize, donated by Professor James Busvine in 1987, is awarded each year for outstanding performance.

- Full programme specification (pdf) (http://www.lshtm.ac.uk/edu/qualityassurance/medic_progspec.pdf)
- Intercalating this course (http://www.lshtm.ac.uk/study/intercalate)

Visit the website http://www.lshtm.ac.uk/study/masters/msbcdv.html

Objectives

By the end of this course students should be able to:

- demonstrate advanced knowledge and understanding of the biology of vectors and intermediate hosts of human pathogens together with methods for their control

- describe the biology, pathogenesis and diagnosis of parasitic infections in humans and relate these to human health and disease control strategies

- demonstrate a range of specialised technical and analytical skills relevant to vectors and vector-borne diseases

- design and carry out a research project on biology or control of disease vectors, analyse and interpret the results and prepare a report including a critical literature review

- design, undertake and evaluate vector control interventions, and show written and verbal competence in communicating scientific information

Structure

Term 1:
There is a one-week orientation period that includes an introduction to studying at the School, sessions on key computing and study skills and an introduction to major groups of pathogens, followed by three compulsory core modules:

- Parasitology & Entomology
- Analysis & Design of Research Studies
- Critical Skills for Tropical Medicine

Sessions on basic computing, molecular biology and statistics are run throughout the term for all students.

Terms 2 and 3:
Students take a total of five modules, one from each timetable slot (Slot 1, Slot 2 etc.). Some modules can be taken only after consultation with the Course Director.

*Recommended modules

- Slot 1:
Epidemiology & Control of Malaria*
Designing Disease Control Programmes in Developing Countries
Molecular Biology & Recombinant Techniques

- Slot 2:
Advanced Diagnostic Parasitology*
Design & Analysis of Epidemiological Studies
Statistical Methods in Epidemiology

- Slot 3:
Vector Sampling, Identification & Incrimination (compulsory)

- Slot 4:
Vector Biology & Vector Parasite Interactions*
Epidemiology & Control of Communicable Diseases
Molecular Biology Research Progress & Applications
Population Dynamics & Projections

- Slot 5:
Integrated Vector Management (compulsory)

Further details for the course modules - http://www.lshtm.ac.uk/study/currentstudents/studentinformation/msc_module_handbook/section2_coursedescriptions/tbcd.html

Residential Field Trip

There is a compulsory one week field course, after the Term 3 examinations, on vector and parasite sampling and identification methods. The cost of £630 is included in the field trip fee.

Project Report

During the summer months (July - August), students complete a field or laboratory research project on an appropriate entomological topic, for submission by early September.

Titles of some of the recent summer projects completed by students on this MSc

Due to our collaborative networking, students are given the opportunity to conduct research projects overseas. This unique experience provides students with skills that are highly desirable to potential employers. The majority of students who undertake projects abroad receive financial support for flights from the School's trust funds set up for this purpose.

Find out how to apply here - http://www.lshtm.ac.uk/study/masters/msbcdv.html#sixth

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With human bones representing a major portion of archaeological finds, it’s not surprising that we rely on their analysis to further our understanding of ancient societies. Read more

Programme description

With human bones representing a major portion of archaeological finds, it’s not surprising that we rely on their analysis to further our understanding of ancient societies.

This programme gives you the skills to work with these archaeological treasures to discover evidence of population structure, biological affinities, cultural behaviour, and patterns of disease in prehistoric and historic civilisations.

You’ll be part of a steadily growing community, as interest in osteoarchaeology expands globally and the discipline takes its place as a vital means of understanding our past.

Combining theoretical learning with hands-on practice, the course provides a grounding in osteoarchaeological method and theory, which will be essential to your handling of specimens recovered from archaeological sites.

Programme structure

Throughout the programme you’ll take part in lectures, seminars and practical work with archaeological skeletal assemblages and reference collections.

You’ll complete six courses:

Analytical Methods in Human Osteology
Bioarchaeological Interpretation
Human Musculoskeletal Anatomy
Practical Osteology
Research Sources and Strategies in Archaeology
Skeletal Pathology

In addition to essays, reports, and practical assessments, you’ll submit a dissertation on a research topic of your choosing.

Learning outcomes

On successful completion of the programme, you will be able to:

identify and interpret human bone remains from archaeological sites
develop hypothesis testing skills
carry out relevant scientific analyses, often in cooperation with experts in other disciplines
engage in theoretical and methodological discussions relevant to osteoarchaeology
design research strategies based on transferable skills providing a basis for advanced studies (PhD and beyond)

Career opportunities

The programme provides a foundation for further study or your career. Following successful completion of the programme, a large proportion of students continue their studies to PhD level and beyond, and the programme provides the necessary osteological knowledge for PhD study involving human remains.

You may wish to work in mainstream archaeology, or develop a career in museums or archaeological units.

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Changing environmental, social and agricultural conditions are a threat to animal and human health and welfare. Many infectious diseases can pass between animals and humans, while food production, human diet and community stability are harmed by diseases that infect livestock and wildlife. Read more
Changing environmental, social and agricultural conditions are a threat to animal and human health and welfare.

Many infectious diseases can pass between animals and humans, while food production, human diet and community stability are harmed by diseases that infect livestock and wildlife. Emerging veterinary infectious diseases and human diseases, such as highly pathogenic avian influenza viruses, emphasise the threat posed by these issues.

The One Health approach recognises the relationship between health and disease at the human, animal and environment interfaces and has become an important focus in both medical and veterinary science. It promotes a “whole of society” treatment of health hazards and a systemic change of perspective in the management of risk.

Under the microscope

If you are interested in One Health and the control of infectious disease (particularly in the developing world), then this unique course could be for you. We welcome applications from individuals with a background in public health, veterinary sciences, animal or biological sciences, social and environmental sciences, ecology and wildlife health. If you are interested in this field, but do not have the relevant background, please speak with the course directors who can consider such cases on an individual basis.

The course is delivered jointly by the RVC, University of London and the London School of Hygiene and Tropical Medicine (LSHTM).

The course

The MSc consists of eight modules of 15 credits each, plus a compulsory research project (MSc only) of 60 credits -15 credits for integration of One Health principles learnt through development of and writing a research proposal and 45 credits for the empirical or trans-disciplinary innovative study.

The MSc consists of the following modules:
- Foundations of One Health
- Introduction to disease agents for One Health
- Infectious disease emergence core module
- Introduction to One Health epidemiology and surveillance
- Economics of One Health
- One Health skills development
- Medical anthropology and public health
- Optional module choice from; vector biology and vector parasite interactions, environmental epidemiology, epidemiology and control of communicable diseases, and globalisation and health
- Research project (MSc only)

How will I learn?

The MSc may be completed full-time in one year or part-time over two to three years, and consists of eight taught modules and a research project.

The PGDiploma is shorter (eight modules with no research project component) and may be completed in two terms.

The course starts in September each year and you will split your time between the RVC and LSHTM. Students studying the MSc will then undertake a four-month research project in an area and country of their choice.

Learning outcomes

The course will provide you with:

- A comprehensive foundation on the principles of diseases in the context of socio-ecological systems, global health and food safety
- Knowledge and skills in relation to One Health methodologies, transdisciplinary interactions and in using a systems approach

At the end of the course you will be able to:

- Understand the One Health concept and approach problem solving using a trans-disciplinary methodology
- Understand the origin, context and drivers of infectious disease at the human, animal and environment interface
- Evaluate impacts of multi-host infections on human, animal and ecosystem health and economics directly, or indirectly, via food, disease vectors or the environment.
- Develop a One Health systems approach to complex disease issues in monitoring, surveillance, diagnosis, prevention and control
- Critically review published literature
- Design a research project (MSc students only)

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The graduate program in Human Nutrition offers opportunities for advanced study and original investigations in basic and applied human nutrition at both the master’s and doctoral levels. Read more
The graduate program in Human Nutrition offers opportunities for advanced study and original investigations in basic and applied human nutrition at both the master’s and doctoral levels. The curriculum includes coursework and thesis research through laboratory or field work in a variety of areas relevant to human nutrition including nutrient metabolism, diet and disease, nutrition through the life cycle and nutrition behaviours.

Research projects also examine environmental, social, and individual determinants of food choices and eating patterns; this includes better understanding of socio-cultural effects on diet, and the impact living in “food deserts” can have on good health.

International nutrition projects in Cambodia, Zambia, Rwanda, and other countries seek to improve maternal, infant, and child nutrition.

The program is enriched through collaboration with colleagues in graduate programs such as Applied Animal Biology, Food Science, Medicine, Nursing, Pharmaceutical Sciences, and others.

Coursework selected in consultation with the student's supervisory committee includes graduate courses in human nutrition and from other areas relevant to each student's research.

Research facilities are housed both within the Family and Nutritional Sciences (FNS) Building and, on a shared basis, in other buildings on campus. Within the FNS Building, the research facilities include various modern analytical laboratories and other equipment for conducting biochemical and basic molecular biological research, and computers for conducting dietary and qualitative data analysis.

Quick Facts

- Degree: Master of Science
- Specialization: Human Nutrition
- Subject: Health and Medicine
- Mode of delivery: On campus
- Program components: Coursework + Thesis required
- Faculty: Faculty of Land and Food Systems

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