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Masters Degrees (Genetic Toxicology)

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One of the most rapidly developing areas of toxicology is the use of molecular, cell biology and omics to identify adverse outcome pathways (AOPs) and to develop a mechanistic understanding of chemical toxicity at the cellular and molecular level. Read more
One of the most rapidly developing areas of toxicology is the use of molecular, cell biology and omics to identify adverse outcome pathways (AOPs) and to develop a mechanistic understanding of chemical toxicity at the cellular and molecular level. This is not only of fundamental interest (i.e., understanding the mechanism of action) but it also relates to an increased need for a mechanistic component in chemical risk assessment and development of high throughput screens for chemical toxicity.

The MRes in Molecular Mechanistic Toxicology is a one-year full-time programme that provides students with a research-orientated training in a lively, highly interactive teaching and research environment.

Programme content

The programme is coordinated by the School of Biosciences, which is recognised internationally as a major centre for both teaching and research in Toxicology. Molecular Toxicology is a major component of the School of Biosciences research activities along with interactions with other departments including Chemistry and the Medical School.

Specific areas of active research include:

- Mechanisms of cell toxicity
- Development of novel DNA binding chemicals
- Cellular proliferation and differentiation
- Environmental genomics and metabolomics
- Molecular biomarkers of genotoxicity, oxidative stress and cellular responses
- Role of environmental and genetic factors in disease
- Learning and teaching

Two five-week taught modules are held in Semester 1 in conjunction with the taught MSc in Toxicology programme. Training in generic and laboratory research skills is also an important element of the programme. The programme also includes a six-month research project, which provides students with an opportunity for further advanced research training and hands-on experience of molecular and cellular biology techniques embedded in a research laboratory. Research projects can take place either in academic or industrial institutions.

About the School of Biosciences

As one of the top biosciences departments in the UK, our research covers the entire spectrum of cutting-edge biosciences. We are home to the Institute of Microbiology and Infection and part of the University’s Systems Science for Health initiative.
Our research focuses on a number of important themes that run through modern biological and biochemical research: Biosystems and Environmental Change; Microbiology and Infection; Molecules, Cells, Signalling and Health; and Plant Science.
Our postgraduate students join a diverse international community of staff and students. For students on research degrees, the annual Biosciences Graduate Research Symposium, organised by PhD students, is an example of an event where the whole School comes together to talk about science.
We have extensive high-technology facilities in areas such as functional genomics, proteomics and metabolomics, including a world-class Advanced Mass Spectrometry Facility. Our cutting-edge facilities extend to protein structure determination and analysis, confocal microscopy, drug discovery, horticulture, structural biology and optical imaging. The £8 million Phenome Centre Birmingham is a large metabolic phenotyping facility led by internationally recognised metabolomics and clinical experts at the University of Birmingham, in collaboration with Birmingham Health Partners.

Funding and Scholarships

There are many ways to finance your postgraduate study at the University of Birmingham. To see what funding and scholarships are available, please visit: http://www.birmingham.ac.uk/postgraduate/funding

Open Days

Explore postgraduate study at Birmingham at our on-campus open days.
Register to attend at: http://www.birmingham.ac.uk/postgraduate/visit

Virtual Open Days

If you can’t make it to one of our on-campus open days, our virtual open days run regularly throughout the year. For more information, please visit: http://www.pg.bham.ac.uk

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The need to develop new strategies to combat diseases remains a major global challenge. Read more

The need to develop new strategies to combat diseases remains a major global challenge. This programme provides advanced training in the mechanisms underpinning a spectrum of infectious and non-infectious diseases, including viral, bacterial and parasitic infections, cancer, neurodegeneration, cardiovascular disease and chromosomal abnormalities. You’ll also explore current and emerging diagnostic and treatment strategies.

You’ll learn about the latest molecular, genetic and cellular approaches being used to understand, diagnose and treat human disease, including traditional methods such as polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA), and novel methods involving genome and proteome analysis. You’ll have the opportunity to investigate the role of the immune system in the response to infection and disease, covering topics such as innate and adaptive immunity, allergy and immune evasion.

You’ll study in a faculty ranked 6th in the UK for its research impact in the recent Research Excellence Framework (REF 2014), and you’ll graduate with the solid base of scientific knowledge and specialist skills valued by employers.

Course content

You’ll gain an overview of a range of modern techniques and methodologies that underpin contemporary biomolecular sciences through the investigation of five topic areas: molecular biology, structural biology, cell imaging and flow cytometry, high throughput techniques and transgenic organisms. You’ll also conduct an extended practical investigation in the form of a laboratory-based project, involving practical training in a range of modern molecular biology and protein engineering techniques such as gene cloning, PCR, mutagenesis, protein expression, protein purification and analysis.

Added to this is an independent research project in an area of infection, immunity or human disease which provides substantial subject-specific training.

Specialist taught modules make up the remaining part of the programme and cover topics such as infectious and non-infectious disease, advanced immunology, medical diagnostics and treatment of infectious diseases and cancer. If you have have previous experience of immunology, you could opt to investigate the structure, regulation and development of the pharmaceutical manufacturing sector, or explore aspects of human toxicology, including the actions of toxicants on the cardiovascular, immune and nervous systems, kidneys, liver and lungs, genetic toxicology and chemical carcinogenesis, and the effects of chemicals on fetal development.

In the final part of the course you'll work on an independent laboratory-based research project related to your course options. You’ll receive extensive training in experimental design, the practical use of advanced techniques and technologies, data analysis and interpretation, and will be assigned a research project supervisor who will support and guide you through your project.

Course structure

Compulsory modules

  • Advanced Immunology 10 credits
  • Infectious & Non-infectious Diseases 10 credits
  • Practical Bioinformatics 10 credits
  • Medical Diagnostics 10 credits
  • MSc Bioscience Research Project Proposal 5 credits
  • Treatment of Infectious Disease and Cancer 10 credits
  • Research Planning and Scientific Communication 10 credits
  • Advanced Biomolecular Technologies 20 credits
  • Protein Engineering Laboratory Project 15 credits
  • Bioscience MSc Research Project 80 credits

For more information on typical modules, read Infection, Immunity and Human Disease MSc in the course catalogue

Learning and teaching

We provide the very best learning resources and academic support and our teaching draws on the University’s world-class research base and highly-qualified professionals from industry, non-governmental organisations and charities.

You’ll experience wide range of teaching methods including formal lectures, interactive workshops, problem-solving, practical classes and demonstrations.

Through your research project and specialist modules, you’ll receive substantial subject-specific training. Our teaching and assessment methods are designed to develop you into a scientist who is able to think independently, solve problems, communicate effectively and demonstrate a high level of practical ability.

Assessment

We use a variety of assessment methods: multiple-choice testing, practical work, data handling and problem solving exercises, group work, discussion groups (face-to-face and online), computer-based simulation, essays, posters and oral presentations.

Career opportunities

The strong research element of the Infection, Immunity and Human Disease MSc, along with the specialist and generic skills you develop, mean you’re equipped for a wide range of careers.

Our graduates work in diverse posts, ranging from bioscience-related research through to scientific publication, teacher training, health and safety and pharmaceutical market research.

Links with industry

We have a proactive Industrial Advisory Board who advise us on what they look for in graduates and on employability-related skills within our programmes.

We collaborate with a wide range of organisations in the public and commercial sectors. Many of these are represented on our Industrial Advisory Board. They include:

  • GlaxoSmithKline
  • Ernst and Young
  • The Food and Environment Research Agency
  • The Health Protection Agency
  • MedImmune
  • Thermofisher Scientific
  • Hays Life Sciences
  • European Bioinformatics Institute
  • Smaller University spin-out companies, such as Lumora

Industrial research placements

Some of our partners offer MSc research projects in their organisations, allowing students to develop their commercial awareness and build their network of contacts.

Further study

A substantial proportion of our graduates undertake further study at Leeds or elsewhere. Recent graduates have gone on to:

  • PhD positions in the UK, USA and overseas eg at the Max Planck Institute, Germany
  • research post at Harvard School of Public Health, Botswana.

Careers support

We encourage you to prepare for your career from day one. That’s one of the reasons Leeds graduates are so sought after by employers.

The Careers Centre and staff in your faculty provide a range of help and advice to help you plan your career and make well-informed decisions along the way, even after you graduate. Find out more at the Careers website.



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This Masters course will open the door to a fascinating and fast-moving sector of analytical science that will build on your previous undergraduate studies, in chemistry, biology or other appropriate science courses. Read more
This Masters course will open the door to a fascinating and fast-moving sector of analytical science that will build on your previous undergraduate studies, in chemistry, biology or other appropriate science courses. You will gain knowledge and scientific skills that are directly applicable to the field of forensic science, with prospects of employment in forensic science laboratories as well as in other analytical science laboratories.

The course involves a unique combination of forensic chemistry and forensic biology, covering subjects such as trace evidence, toxicology and DNA analysis. Once you have covered the underlying principles of both areas, you can then specialise in your chosen field for your MSc research project.

The course is accredited by the Chartered Society of Forensic Sciences, which enhances its credibility and currency among potential employers.

This course can also be taken part time - for more information, please view this web-page: https://www.northumbria.ac.uk/study-at-northumbria/courses/forensic-science-dtpfrs6/

Learn From The Best

Our teaching team are active researchers who routinely incorporate their expertise and enthusiasm into their teaching. Many of the staff have worked in forensic science laboratories and have been involved in high profile cases such as the Stephen Lawrence, Joanna Yeates, Suffolk strangler and Jigsaw murder cases. Their areas of research include toxicology, the analysis of fibres and their transfer and persistence and the analysis of ancient DNA.

Academic staff include former forensic biologists, forensic toxicologists, and forensic fibre experts. They continue to maintain close links with the industry including the police and practising forensic scientists. Many of them are well-established within professional forensic science societies and organisations, which directly inform policy and practices within the field.

Teaching And Assessment

Our teaching will give you a solid grounding in all the technical areas that are key to forensic science, while simultaneously developing the higher level of independent thinking and advanced interpretation that is expected at Masters level. To support your learning journey, many of the staff have an ‘open door’ policy which makes it easy to ask questions; it’s also possible to book appointments with them so that you can work through queries about lab work, concepts and theories, and any other aspects of the subject.

We use different types of assessments: some will contribute to your final grade while others will be used to provide you with guidance on your progress and reinforce your learning. You can expect both your tutors and your peers to provide useful comments and feedback throughout the course.

Module Overview
AP0700 - Graduate Science Research Methods (Core, 20 Credits)
AP0703 - Subject Exploration (Core, 20 Credits)
AP0708 - Applied Sciences Research Project (Core, 60 Credits)
AP0723 - Practices & Procedures in Forensic Science (Core, 20 Credits)
AP0724 - Forensic Toxicology & Drugs of Abuse (Core, 20 Credits)
AP0725 - Criminalistics (Core, 20 Credits)
AP0726 - Forensic Genetics (Core, 20 Credits)

Learning Environment

You will have access to a dedicated crime scene house to enable you to examine simulated crime scenes. Students can also access Return to Scene (R2S) software which provides a 360 degree interactive scan of a crime scene allowing you to perform further analysis in detail after you have left the scene. Northumbria University has also invested heavily in an impressive suite of analytical equipment allowing you to gain first-hand experience of the techniques used in operational laboratories.

We use a range of technologies to enhance your learning, with tools including web-based self-guided exercises, online tests with feedback, and electronic discussion boards. These tools support and extend the material that is delivered during lectures.

You will have 24/7 term-time access to Northumbria’s library, which was ranked #2 in the Times Higher Education Student Experience Survey for 2015 and has been accredited by the UK Government for Customer Service Excellence since 2010.

Research-Rich Learning

We host the Northumbria University Centre for Forensic Science and our research directly impacts on what and how you learn. Northumbria is helping to push the frontiers of knowledge in areas such as:
-Forensic fibre comparisons using statistical and chemometric approaches
-DNA profiling in contexts such as injuries to children and poaching of wildlife
-Human genetic and phenotypic variation
-Analytical toxicology

As part of the course, you will undertake a Masters project that will require you to evaluate relevant literature as well as to develop your ideas within the context of existing research. The project will involve information retrieval, critical appraisal, presentation of aims and strategy, development of advanced analytical and problem-solving skills, the discussion and interpretation of results, and the composition of a written dissertation. Each project will be aligned to an active area of research that is specific to an academic member of staff.

Give Your Career An Edge

This course is accredited by the Chartered Society of Forensic Sciences. This reflects the relevance and rigour of the curriculum, and provides assurance of workplace-ready knowledge and application.

The focus on practical laboratory work, combined with the mix of group work, independent learning and professional practice, will help ensure that you develop skills that are transferable to a range of careers and disciplines.

Throughout your time at Northumbria we will prompt you to reflect on your self-development through the Higher Education Achievement Report process. We will also encourage you to take advantage of the services of our Careers and Employment Service such as CV advice and interview preparation.

Your Future

Forensic science has gained a high profile through TV dramas and, in the years ahead the sector is likely to be further transformed by technological advances in a number of fields. With an MSc Forensic Science you will be well-placed to take up a fascinating and rewarding role in forensic science laboratories.

What’s more, by developing the attributes of a Masters student, including the ability to solve complex problems, think critically, and work effectively with others and on your own, you will enhance your employability in all sectors of the analytical science industry. You will also be well equipped to pursue further studies at PhD level.

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If you want to discover a cure for a major disease or lesser known disease this programme will help you towards that goal. Read more

Your programme of study

If you want to discover a cure for a major disease or lesser known disease this programme will help you towards that goal. Aberdeen is well know for drug discovery as Insulin was developed at the university and there has always been a strong research focus within the medical sciences to continue finding major innovations in health sciences. You learn how to formulate drugs to understand how they are regulated and the bio-business area. This area has been in rapid growth since the discovery of customised drugs which rely on individual genetic make up to define, small batch drugs which larger drug companies don't manufacture for reasons of scale and economy, and the understanding of biologics to treat diseases.

Drug Discovery is one of the few areas which have continued to expand over the last 5 years, in fact there is a major revolution in treating disease processes with other disciplines assisting.. Drug discovery involves multidisciplinary teams working in academia, biotechnology and pharmaceutical industries. Our MRes in Drug Discovery provides training in across all aspects of drug discovery and development, clinical pharmacology and medical biotechnology. The degree programme consists of one term of taught courses (3 months) followed by 2 individual research projects lasting 16 weeks each.

Courses listed for the programme

Semester 1
Molecular Pharmacology
Small Molecule Drug Discovery
Introduction to Bio-Business and the Commercialisation of Bioscience Research
Basic Skills-Induction
Generic Skills

Optional
Introduction to Molecular Biology
Applied Statistics
Drug Metabolism & Toxicology

Semester 2
Research Project
Optional
Advanced Bio-Business and the Commercialisation of Bioscience Research
Biologic Drug Discovery
Basic Research Methods

Semester 3
Research Project 2

Find out more detail by visiting the programme web page
https://www.abdn.ac.uk/study/postgraduate-taught/degree-programmes/54/drug-discovery/

Why study at Aberdeen?

• The university is highly regarded and known as a 'centre for excellence' in drug discovery and commercialisation
• Researchers that teach are active opinion leaders and regulators with further interdisciplinary researchers in other countries and
two British Pharmacological Society Wellcome Gold Medal winners on staff
• The university won the Nobel Prize for the treatment of diabetes and invention of insulin

Where you study

• University of Aberdeen
• Full Time or Part Time
• September

International Student Fees 2017/2018

Find out about fees:
https://www.abdn.ac.uk/study/international/tuition-fees-and-living-costs-287.php

*Please be advised that some programmes have different tuition fees from those listed above and that some programmes also have additional costs.

Scholarships

View all funding options on our funding database via the programme page
https://www.abdn.ac.uk/study/postgraduate-taught/finance-funding-1599.php
https://www.abdn.ac.uk/funding/

Living in Aberdeen

Find out more about:
• Your Accommodation
• Campus Facilities
• Aberdeen City
• Student Support
• Clubs and Societies

Find out more about living in Aberdeen:
https://abdn.ac.uk/study/student-life

Living costs
https://www.abdn.ac.uk/study/international/finance.php

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