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Masters Degrees (Genetic Diagnostic)

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The MSc in Genetic and Genomic Counselling is designed to give students a working knowledge of the principles and practice of Genetic Counselling which will qualify them to practice as Genetic and Genomic Counsellors. Read more
The MSc in Genetic and Genomic Counselling is designed to give students a working knowledge of the principles and practice of Genetic Counselling which will qualify them to practice as Genetic and Genomic Counsellors. The programme will be delivered by University of Glasgow staff in collaboration with NHS staff from the West of Scotland Genetics Service, so that a current perspective on both laboratory diagnostics and clinical services will be obtained. This programme is accredited by the UK Genetic Counsellor Registration Board.

Why this programme

-◾Teaching is based at the Queen Elizabeth University Hospital (QEUH), which includes adult services, children’s services and maternity services, as well as one of the largest diagnostic laboratories in Europe, and a new, purpose-built teaching and learning facility. The close collaboration between University and NHS staff ensures that the MSc in Genetic and Genomic Counselling provides a completely up-to-date representation of genetic services.
◾Counselling and psychology theoretical and research-focused courses are delivered by University staff trained in psychology, providing a firm foundation for the subsequent acquisition of knowledge and skills in genetic counselling facilitated by GCRB-registered Genetic Counsellors.
◾The University of Glasgow Medical Genetics Teaching Staff won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering), to recognise and reward excellence and good practice; they were also finalists in the 2013 awards and are finalists in the category of "Outstanding support for students" in The Herald Higher Education Awards for Scotland in association with UWS 2016.
◾You will develop your skills in problem solving, evaluation and interpretation of diagnostic data, communication of the results of genome testing to patients, literature searches, scientific writing, oral presentations, poster presentations and team working.
◾The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.

Programme structure

Component courses are as follows:

Genetic Disease in Clinical Practice

This course is designed in collaboration with the West of Scotland Genetics Service to give students a working knowledge of the principles and practice of Clinical Genetics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease, and explore the links between genotype and phenotype.

Case Investigations in Medical Genetics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Distress or disorder: reactions to a medical diagnosis

Note: this 10 credit course may be taken by visiting students, for example as professional development.

This course outlines the process of psychosocial adjustment to a diagnosis or test result allowing participants to establish if and when a distress reaction develops into an adjustment disorder. The implications of diagnosis are explored and evidence considered allowing informed decisions about appropriate referrals to other agencies.

Patient empowerment: supporting decisions relating to new diagnoses

Note: this 10 credit course may be taken by visiting students, for example as professional development.

This course reflects on evidence and experience to explore the psychological and social impact of a diagnosis, or illness, and provides strategies to support resilience and coping in patients. Factors related to lived experience, personal beliefs and values, culture, adjustment processes, decision-making, misconceptions, secrecy and guilt are considered to equip participants in the promotion of patient-centred care.

Effective listening and communication skills

Note: this 10 credit course may be taken by visiting students, for example as professional development.

With a focus on experiential learning and student led study, this course outlines the role of counselling skills to facilitate adjustment and to allow an individual to come to terms with change in a safe way to minimise impact. The focus will be on the theory supporting counselling, developing key listening and communication skills and on establishing reflective practice.

Genetic counselling in clinical practice

This course is designed in collaboration with the West of Scotland Clinical Service, and will be delivered by NHS staff, to provide students with in depth understanding of the practical skills required in genetic counselling. The course will facilitate development of appropriate critical understanding, reflective practice and skills in relation to genetic counselling for providing accurate complex genetic information for patients and their families.

Social science research methods

The research methods course will focus on developing students’ research skills primarily in questionnaire-based qualitative and quantitative observational research methods and students will be introduced to ethics procedures for the college of MVLS.

Community placements 1 & 2

These placements, for 16 days and 20 days respectively, will each take place in one or more care settings for individuals with complex needs (adults or children or both) to enable students to gain insight into effects of complex needs on affected individuals and on their family.

Genetic counselling placement 1 & 2

These placements, for eight weeks and six weeks respectively, in different genetics centres will allow students to observe clinical practice in a variety of contexts, and to undertake relevant tasks under supervision within a clinical team that is delivering a genetic service, to enable the student to develop their own skills as a future genetic counsellor. Following each placement students will discuss and share experiences, facilitated by one of the NHS lead team and a counselling supervisor, to further develop their ability to deal with practical and emotional challenges in genetic counselling.

Clinical genomics

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussing the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Career prospects

The programme aims to provide students with skills to work as Genetic Counsellors. This programme is accredited by the Genetic Counsellor Registration Board (GCRB) producing graduates who are eligible for entry as a ‘trainee genetic counsellor’.

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The increasing impact of genetics in healthcare and the development of newer sophisticated technologies requires close collaboration between research scientists, clinical laboratory scientists and clinicians to deliver a high quality service to patients. Read more
The increasing impact of genetics in healthcare and the development of newer sophisticated technologies requires close collaboration between research scientists, clinical laboratory scientists and clinicians to deliver a high quality service to patients. The Clinical Genetics MSc has a specific focus on delivery of the clinical service to patients including risk analysis and application of modern genetic and genomic technologies in medical genetics research and in diagnostics and population screening.

● This is a fully up-to-date Clinical Genetics degree delivered by dedicated, multi-award-winning teaching and clinical staff of the University, with considerable input from hospital-based Regional Genetics Service clinicians and clinical scientists.
● The full spectrum of genetic services is represented, from patient and family counselling to diagnostic testing of individuals and screening of entire populations for genetic conditions: eg the NHS prenatal and newborn screening programmes.
● The Clinical Genetics MSc Teaching Staff won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering). These awards recognise and reward excellence and good practice in postgraduate education.
● The close collaboration between university and hospital staff ensures that the Clinical Genetics MSc provides a completely up-to-date representation of the practice of medical genetics and you will have the opportunity to observe during clinics at the new Queen Elizabeth University Hospital laboratory medicine building.
● The Clinical Genetics degree explores the effects of mutations and variants as well as the theoretically basis of current techniques used in NHS genetics laboratory diagnostics and recent developments in diagnostics (including microarray analysis and the use of massively parallel [“next-generation”] sequencing).
● New developments in genetics are incorporated into the lectures and interactive teaching sessions very soon after they are presented at international meetings or published, and you will gain hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenesis of DNA sequence variants.
● You will develop your skills in problem solving, evaluation and interpretation of genetic data, literature searches, scientific writing, oral presentations, poster presentations and team working.
● This MSc programme will lay the academic foundations on which some students with prior MBChB or MBBS may build in pursuing careers in Clinical Genetics.
● The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.
● For doctors: The Joint Royal Colleges of Physicians’ Training Board (JRCPTB) in the UK recognises the MSc in Clinical Genetics (which was established in 1984) as counting for six months of the higher specialist training in Clinical Genetics.

Programme Structure

Genetic Disease and Clinical Practice

This course is designed in collaboration with the West of Scotland Regional Genetics Service to give students a working knowledge of the principles and practice of Clinical Genetics and Genomics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease. The link from genotype to phenotype, will be explored, with consideration of how this knowledge might contribute to new therapeutic approaches.

Distress or Disorder: Reactions to a medical diagnosis

This course outlines the process of psychosocial adjustment to a diagnosis or test result allowing participants to establish if and when a distress reaction develops into an adjustment disorder. The implications of diagnosis are explored and evidence considered allowing informed decisions about appropriate referrals to other agencies.

Patient Empowerment: Supporting decisions relating to new diagnoses

This course reflects on evidence and experience to explore the psychological and social impact of a diagnosis, or illness, and provides strategies to support resilience and coping in patients. Factors related to lived experience, personal beliefs and values, culture, adjustment processes, decision-making, misconceptions, secrecy and guilt are considered to equip participants in the promotion of patient-centred care.

Effective listening and communication skills

With a focus on experiential learning and student led study, this course outlines the role of counselling skills to facilitate adjustment and to allow an individual to come to terms with change in a safe way to minimise impact. The focus will be on the theory supporting counselling, developing key listening and communication skills and on establishing reflective practice.

Case Investigations in Medical Genetics and Genomics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Clinical Genomics

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussion the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Disease Screening in Populations

This course will cover the rationale for, and requirements of, population screening programmes to detect individuals at high risk of particular conditions, who can then be offered diagnostic investigations. Students will work in groups to investigate and report on, a screening programme of their choice from any country.

Dissertation

The course will provide students with the opportunity to carry out an independent investigative project in the field of Medical Genetics and Genomics.

Teaching and Learning Methods

A variety of methods are used, including problem-based learning, case-based learning, lectures and tutorials. These are supplemented by a wide range of course-specific electronic resources for additional learning and self-assessment. As a result, you will develop a wide range of skills relevant to careers in clinical genetics. These skills include team-working and data interpretation. You will use the primary scientific literature as an information resource, although textbooks such as our own Essential Medical Genetics will also be useful. You will have the options of: attending genetic counselling clinics and gaining hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenicity of DNA sequence variants.

Visit the website for more information http://www.gla.ac.uk/postgraduate/taught/clinicalgenetics/#/programmestructure

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The increasing impact of genetics in healthcare and the development of newer sophisticated technologies requires contributions from research scientists, clinical laboratory scientists and clinicians to investigate the causes of, and therefore permit optimal management for, diseases for which alterations in the genome, either at the DNA sequence level or epigenetic level, play a significant role. Read more
The increasing impact of genetics in healthcare and the development of newer sophisticated technologies requires contributions from research scientists, clinical laboratory scientists and clinicians to investigate the causes of, and therefore permit optimal management for, diseases for which alterations in the genome, either at the DNA sequence level or epigenetic level, play a significant role. Collaboration between staff from the University of Glasgow and the NHS West of Scotland Genetics Service enables the MSc in Medical Genetics and Genomics to provide a state-of-the-art view of the application of modern genetic and genomic technologies in medical genetics research and diagnostics, and in delivery of a high quality genetics service to patients, as well as in design of targeted therapies.

Why this programme

◾This is a fully up-to-date Medical Genetics degree delivered by dedicated, multi-award-winning teaching and clinical staff of the University, with considerable input from hospital-based Regional Genetics Service clinicians and clinical scientists.
◾The full spectrum of genetic services is represented, from patient and family counselling to diagnostic testing of individuals and screening of entire populations for genetic conditions: eg the NHS prenatal and newborn screening programmes.
◾The MSc Medical Genetics Course is based on the south side of the River Clyde in the brand new (2015) purpose built Teaching & Learning Centre, at the Queen Elizabeth University Hospitals (we are located 4 miles from the main University Campus). The Centre also houses state of the art educational resources, including a purpose built teaching laboratory, computing facilities and a well equipped library. The West of Scotland Genetic Services are also based here at the Queen Elizabeth Campus allowing students to learn directly from NHS staff about the latest developments to this service.
◾The Medical Genetics MSc Teaching Staff have won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering). These awards recognise and reward excellence and good practice in postgraduate education.
◾The close collaboration between university and hospital staff ensures that the Medical Genetics MSc provides a completely up-to-date representation of the practice of medical genetics and you will have the opportunity to observe during clinics and visit the diagnostic laboratories at the new Southern General Hospital laboratory medicine building.
◾The Medical Genetics degree explores the effects of mutations and variants as well as the current techniques used in NHS genetics laboratory diagnostics and recent developments in diagnostics (including microarray analysis and the use of massively parallel [“next-generation”] sequencing).
◾New developments in medical genetics are incorporated into the lectures and interactive teaching sessions very soon after they are presented at international meetings or published, and you will gain hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenesis of DNA sequence variants.
◾You will develop your skills in problem solving, experimental design, evaluation and interpretation of experimental data, literature searches, scientific writing, oral presentations, poster presentations and team working.
◾This MSc programme will lay the academic foundations on which some students may build in pursuing research at PhD level in genetics or related areas of biomedical science or by moving into related careers in diagnostic services.
◾The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.
◾For doctors: The Joint Royal Colleges of Physicians’ Training Board (JRCPTB) in the UK recognises the MSc in Medical Genetics and Genomics (which was established in 1984) as counting for six months of the higher specialist training in Clinical Genetics.
◾The Medical Council of Hong Kong recognises the MSc in Medical Genetics and Genomics from University of Glasgow in it's list of Quotable Qualifications.

Programme structure

Genetic Disease: from the Laboratory to the Clinic

This course is designed in collaboration with the West of Scotland Regional Genetics Service to give students a working knowledge of the principles and practice of Medical Genetics and Genomics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease. The link from genotype to phenotype, will be explored, with consideration of how this knowledge might contribute to new therapeutic approaches.

Case Investigations in Medical Genetics and Genomics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Clinical Genomics

Students will take this course OR Omic Technologies for Biomedical Sciences OR Frontiers in Cancer Science.

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussion the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Omic technologies for the Biomedical Sciences: from Genomics to Metabolomics

Students will take this course OR Clinical Genomics OR Frontiers in Cancer Science.

Visit the website for further information

Career prospects

Research: About half of our graduates enter a research career and most of these graduates undertake and complete PhDs; the MSc in Medical Genetics and Genomics facilitates acquisition of skills relevant to a career in research in many different bio-molecular disciplines.

Diagnostics: Some of our graduates enter careers with clinical genetic diagnostic services, particularly in molecular genetics and cytogenetics.

Clinical genetics: Those of our graduates with a prior medical / nursing training often utilise their new skills in careers as clinical geneticists or genetic counsellors.

Other: Although the focus of teaching is on using the available technologies for the purpose of genetic diagnostics, many of these technologies are used in diverse areas of biomedical science research and in forensic DNA analysis. Some of our numerous graduates, who are now employed in many countries around the world, have entered careers in industry, scientific publishing, education and medicine.

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The practice of medicine, especially in the disciplines of Pathology and Genetics is increasingly reliant on Genomic technology. Read more

The practice of medicine, especially in the disciplines of Pathology and Genetics is increasingly reliant on Genomic technology. The aim of this programme is to increase the knowledge and capability of scientific and clinical staff using genetic data in their daily work allowing them to engage confidently with the scientific concepts of Molecular Pathology and Genomic Medicine, and to use their skills to improve patient care. The programme could also provide a foundation for those students interested in developing a clinical academic career.

The University of Edinburgh is at the forefront of Genomic Technology. To adequately realise the potential of these technologies in a diagnostic setting this programme will cover the scientific underpinning and clinical application of genomic technology to enable clinicians and scientists to provide maximum benefit to patients.

The programme will provide a structured environment for students wishing to develop cutting edge knowledge and practical skills in Clinical Genomics and Molecular Pathology. The programme structure is designed around three central themes: scientific foundation, diagnostics, and patient management and treatment.

Programme structure

The PG Cert is comprised of four compulsory courses, totalling 60 credits.

Students will learn via a mixture of guided online activities, in-person tutorials, and in course four, an extended project. In addition to structured learning, students are expected to conduct independent study and read around the subject area.

Students will develop their critical analysis skills through evaluation of primary research articles and reviews. Students will learn how to perform variant analysis and next generation sequencing data analysis using relevant bioinformatics tools. Students can also expect to develop the communication skills required for interacting with the major stakeholders of genomic information: clinical scientists, doctors and patients.

Teaching is performed by a variety of staff who are leaders in their field, as well as experienced educators. The core teaching team is comprised of staff from the NHS Lothian Clinical Genetics Service and Pathology departments. Additional teaching is performed by clinical and scientific staff from across Edinburgh University and the UK. In addition, the programme has a dedicated teaching teaching fellow, who will provide academic and pastoral support throughout all courses.

Postgraduate Professional Development (PPD)

Aimed at working professionals who want to advance their knowledge through a postgraduate-level course(s), without the time or financial commitment of a full Postgraduate Certificate.

You may take a maximum of 50 credits worth of courses over two years through our PPD scheme. These lead to a University of Edinburgh postgraduate award of academic credit. Alternatively, after one year of taking courses you can choose to transfer your credits and continue on to studying towards a higher award on the Postgraduate Certificate programme. Any time spent studying PPD will be deducted from the amount of time you will have left to complete a Postgraduate Certificate programme.

Learning outcomes

  1. Explain how genetic variation is involved in human disease and the development of cancer
  2. Critically evaluate molecular pathology diagnostics and select the appropriate diagnostic for disease stratification to determine patient treatment
  3. Analyse next generation sequence data in the context of germline mutations that cause human genetic disease, and somatic mutations involved in cancer
  4. Understand how genetic variation can be a major determinant of patient treatment and apply this knowledge to clinical scenarios in Genomic Medicine and Molecular Pathology

The programme will adopt a blended learning format, with teaching delivered via online as a eLectures and interviews, in-person tutorials, and online interactive content.

Programme materials and resources will all be available in the virtual learning environment, Learn. Learn provides an interactive forum for students to engage with other learners and the programme teaching staff. Multiple feedback opportunities will be integrated within each course and will comprise of weekly interactive online quizzes, discussion boards and office hours. In-person tutorials will also represent an important feedback opportunity for students. Assessment will vary slightly with each course, common assessment modalities include structured written assignments, presentations and data analysis reports.

Career opportunities

The programme is aimed primarily at NHS laboratory and clinical staff. It is designed for anyone wishing to expand their understanding of molecular pathology and how it applies to clinical diagnostics. The PG Cert will be of use to a wide range of individuals as it can be used to support FRC Path, Clinical Scientist Development and Genetic Technologist Registration. It can be used as a component of STP and could potentially contribute the first 60 credits of MSc. It will also provide the scientific underpinning for Genetic Counselling.



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The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents. Read more

The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents.

About this degree

The programme provides a thorough grounding in modern approaches to the understanding of the genetics of disease alongside the cutting-edge research methods and techniques used to advance our understanding of development of disease. Core modules provide a broad coverage of the genetics of disease, research skills and social aspects, whilst specialised streams in Inherited Diseases, Pharmacogenetics and Computational Genomics, in which students can qualify, and the research project allow more in-depth analysis in areas of genetics.

Students undertake modules to the value of 180 credits.

The programme consists of four core modules (60 credits) and two specialist modules (30 credits) and a research project culminating in a dissertation (90 credits).

A Postgraduate Diploma consisting of six modules (four core modules in term one and two modules within the selected stream in term two) is offered, full-time nine months.

A Postgraduate Certificate consisting of four core modules in term one (60 credits) is offered, full-time three months.

Core modules

  • Advanced Human Genetics: Research Principles
  • Understanding Bioinformatics Resources and their Applications
  • Human Genetics: Core Skills
  • Basic Statistics for Medical Sciences

Specialist modules

In term two you will take specialist modules depending on the specialist stream you select: Inherited Disease (A); Pharmacogenetics (B); Computational Genomics (C). 

  • Applications in Human Genetics (A)
  • Either Genetics of Cardiovascular Disease or Genetics of Neurological Disease (A)
  • Clinical Applications of Pharmacogenetic Tests (B)
  • Anti-Cancer Personalised Medicine or Pharmacogenomics, adverse drug reactions and biomarkers (B)
  • Applications in Human Genetics (C)
  • Statistics for Interpreting Genetic Data (C)

Dissertation/report

Students undertake an original research project investigating topical questions in genetics and genetics of human disease which culminates in a dissertation of 12,000 to 14,000 words and an oral presentation.

Teaching and learning

Students develop their knowledge and understanding of genetics of human diseases through a combination of lectures, seminars, tutorials, presentations and journal clubs. Taught modules are assessed by unseen written examination and/or, written reports, oral presentations and coursework. The research project is assessed by the dissertation and oral presentation. 

Further information on modules and degree structure available on the UCL Genetics Institute website.

Further information on modules and degree structure is available on the department website: Genetics of Human Disease MSc

Careers

Advanced training in genetic techniques including bioinformatic and statistical approaches positions graduates well for PhD studentships in laboratories using genetic techniques to examine diseases such as heart disease, cancer and neurological disorders. Another large group will seek research jobs in the pharmaceutical industry, or jobs related to genetics in healthcare organisations.

Recent career destinations for this degree

  • Laboratory Specialist, King Abdullah Medical Complex
  • Non-Clinical Research Associate, University of Oxford
  • Trainee Geneticist, Oxford University Hospitals NHS Trust
  • PhD in Cardiovascular Science, UCL
  • Genomic Research Technician, Genome Centre

Employability

The MSc in Genetics of Human Disease facilitates acquisition of knowledge and skills relevant to a career in research in many different biomedical disciplines. About half of our graduates enter a research career by undertaking and completing PhDs and working as research associates/scientists in academia. Some of our graduates go on to jobs in the pharmaceutical industry, while others enter careers with clinical genetic diagnosis services, particularly in molecular genetics, in healthcare organisations and hospitals around the world. Those graduates with a prior medical training often utilise their new skills as clinical geneticists.

Careers data is taken from the ‘Destinations of Leavers from Higher Education’ survey undertaken by HESA looking at the destinations of UK and EU students in the 2013–2015 graduating cohorts six months after graduation.

Why study this degree at UCL?

UCL is in a unique position to offer both the basic science and application of modern genetics to improve human health. The programme is a cross-faculty initiative with teaching from across the School of Life and Medical Sciences (SLMS) at UCL.

Students will be based at the UCL Genetics Institute (UGI), a world-leading centre which develops and applies biostatistical and bioinformatic approaches to human and population genetics. Opportunities to conduct laboratory or computational-based research projects are available in the laboratories of world-leading geneticists affiliated to the UGI.

Research Excellence Framework (REF)

The Research Excellence Framework, or REF, is the system for assessing the quality of research in UK higher education institutions. The 2014 REF was carried out by the UK's higher education funding bodies, and the results used to allocate research funding from 2015/16.

The following REF score was awarded to the department: Division of Biosciences

82% rated 4* (‘world-leading’) or 3* (‘internationally excellent’)

Learn more about the scope of UCL's research, and browse case studies, on our Research Impact website.



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The biotechnological applications of molecular biology underpin major industries in the medical and agricultural sectors. Insights from the study of genetic material are already benefitting the development of new diagnostic tests, therapeutic agents, bioenergy production systems, improved crops and more. Read more

About the course

The biotechnological applications of molecular biology underpin major industries in the medical and agricultural sectors. Insights from the study of genetic material are already benefitting the development of new diagnostic tests, therapeutic agents, bioenergy production systems, improved crops and more. The range and value of these developments is rapidly increasing.

This exciting MSc Molecular Biology and Biotechnology program provides training for bioscience graduates to develop confidence and independence in their practical skills and knowledge relevant to careers in this area. Successful graduates will be ready to undertake further study at PhD level or to enter employment in the biotechnology sector.

You’ll learn essential practical skills; study the relevant theory in the Departments of Molecular Biology and Biotechnology (MBB) and Chemical and Biological Engineering (CBE); and carry out an individual research project, in which you’ll learn how to design and conduct research, keep records and present the research in different styles.

Where your masters can take you

Our graduates work in health care, pharmaceuticals, food safety and production, brewing and agrochemicals. Many of our masters students go on to do a PhD then pursue a career in research; others have gained entry to the prestigious NHS Scientist Training Programme (STP).

An international reputation

The 2014 Research Excellence Framework (REF) ranks Sheffield No 1 for biomedical research and in the UK top five for biological sciences generally. We have regular seminars from distinguished experts, and our motivated staff undertake collaborative research ranging from biotechnology to medicine.

Teaching and assessment

Our masters courses give you a solid grounding in experimental science, with personal supervision and tutorials by experienced scientists, based in modern and well-equipped labs, leading on to a research project in which you design and conduct your own research. You will learn cutting edge science from research leaders, and gain practice in reading the scientific literature and writing reports. Assessment is based on a combination of coursework, project work, formal examinations and a dissertation.

Core modules

Laboratory Skills in Molecular Bioscience; Principles of Biochemical Engineering; Advanced Research Topics; Literature Review; Research Project (typical research areas include plant genetic engineering, engineering of proteins of commercial importance, or genetic studies by random mutagenesis).

Examples of optional modules

Choose two from: The RNA World, Cells as Factories, Plant Biotechnology, Microbiology of Extreme Environments.

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Research profile. Our Division of Psychiatry is internationally recognised as a world-class clinical research and teaching centre. Read more

Research profile

Our Division of Psychiatry is internationally recognised as a world-class clinical research and teaching centre.

We focus on the mechanisms underlying the development of major psychiatric disorders, including autism, bipolar disorder, depression, dementia and schizophrenia.

Expertise and studies

We have a particular expertise in longitudinal, clinical and biological studies of large cohorts of people at high risk of psychotic disorders drawn from across Scotland. Our studies include:

  • the Edinburgh High Risk Study, which examines 200 young people at high genetic risk of schizophrenia over a period of ten years
  • the Edinburgh Study of Co-Morbidity, which examines teenagers at high cognitive risk for schizophrenia
  • the Bipolar Family Study, which examines over 200 young people at familial risk of bipolar disorder and controls

In psychiatric genetics, we take part in international genome wide association studies and focus on analyses of candidate genes including DISC-1, NDE-1 and DLG-2.

We also have a major focus on the functional genetics of psychiatric illness and have investigated the effects of variation in genes, such as DISC-1, on brain structure and function, as well as their programming during development in stem cell models.

We have demonstrated, for the first time, that structural and functional MRI changes precede the onset of psychosis and could be used as a diagnostic aid.

We have also demonstrated that imaging can be used to separate autism from learning disability in people of matched IQ.

We have made substantial progress in the discovery of genes, including DISC-1, associated with psychosis and have played a leading role in understanding how genetic variation alters brain structure and function and risk for mental illness.

Research methods

The principal methods used are state-of-the-art structural and functional imaging techniques and genetic studies. We are also involved in a number of clinical trials of novel therapeutic interventions.

Major conditions of interest

Our major interests (that straddle the disciplines of Neurology and Psychiatry) include:

  • Autism and learning disability (Andrew Stanfield)
  • Dementia prevention (Craig Ritchie)
  • Bipolar disorder and depression (Andrew McIntosh)
  • Schizophrenia (Stephen Lawrie, Mandy Johnstone)
  • Cognition and Behaviour (collaborations with the Centre for Cognitive Ageing and Cognitive Epidemiology
  • Centre for Cognitive Ageing and Cognitive Epidemiology

We are also closely involved in two philanthropically funded Specialist Centres of Excellence:

Centre for Clinical Brain Sciences

The Division of Psychiatry is a part of the Centre for Clinical Brain Sciences (CCBS) in the Edinburgh Medical School. CCBS integrates laboratory and clinical research to study the causes, consequences and treatment of major brain disorders.

Training and support

Postgraduate students are mentored and supported by at least two supervisors and receive long-term guidance from their thesis committee.

We offer a transferable skills programme and project-specific courses, including opportunities to become involved in science communication and public engagement. In addition, the Division provides clinical case demonstrations and specialist seminars.

Facilities

We offer well-characterised cohorts of patients and expertise in a wide variety of techniques to study biological aspects of psychiatric disorders.



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The Genomic Medicine and Healthcare course has been developed for healthcare professionals including Specialist Medical Practitioners, General Medical Practitioners, Allied Health Professionals, Nurses and Midwives, Genetic Counsellors and those with related undergraduate degrees or equivalent professional qualifications and background experience. Read more

Genomics Medicine and Healthcare Courses

The Genomic Medicine and Healthcare course has been developed for healthcare professionals including Specialist Medical Practitioners, General Medical Practitioners, Allied Health Professionals, Nurses and Midwives, Genetic Counsellors and those with related undergraduate degrees or equivalent professional qualifications and background experience. It will be of interest to health professionals in the UK and internationally and will provide a solid foundation in the core concepts of genetics and genomics applied to modern medicine and healthcare. Although there are other courses covering the subject area, none are completely online so they are difficult and costly for global healthcare professionals to get involved. This course will reach an international audience in a cost effective, flexible and inclusive way, helping to develop a worldwide network of genomic medical and healthcare leaders.

Our course is well timed given increasing public and professional interests in genetic and genome-level diagnostic and predictive testing for clinical management, disease risk evaluation, prevention of major complications and offering the prospect of improved prognosis. Personalised benefits include the option for reproductive choices and reducing lifetime medical or health risks by judicious use of new emerging preventive medicines and devices combined with lifestyle/behaviour modifications.

Diploma in Genomics Medicine and Healthcare Courses

Our online 1 year Postgraduate Diploma in Genomic Medicine & Healthcare is designed to be practical and clinically focused. The course will provide an integrated approach to Genomic Medicine and Healthcare and focus on applying scientific principles to direct patient care. The Genomics Diploma course is worth 120 credits and comprises 6 modules of 20 credits each.

The Diploma course aims to equip graduates with critical knowledge and understanding of genomics medicine. Graduates will be able to apply knowledge for direct clinical benefit and future study. Our Genomics Medicine Diploma course caters to the educational needs of a primary and secondary care audience and is the only one of its kind that is completely accessible online.

Our Genomic Medicine Diploma has been designed for General Medical Practitioners, Specialist Medical Practitioners (for example Paediatrics, General Medicine, Obstetrics & Gynaecology, Medical Oncology), Allied Health Professionals (Clinical Psychologists, Occupational Therapists and Physiotherapists), Nurses (Cancer, Cardiac, Paediatric, Neurology etc.) and Midwives. In addition, the course would be of interest to those with related undergraduate degrees (e.g. Dietetics, Biomedical Science, Pharmacy) or equivalent professional qualifications and background experience

On completion you will demonstrate:

- a systematic understanding of genetics and genomic factors in human diseases
- a critical awareness of current issues affecting the management of inherited human diseases
- an advanced knowledge of clinical genomics that will facilitate decision-making in unpredictable and/or complex situations
- an ability to critically evaluate current research in applied and translational genetics and genomics
- an ability to deliver management strategies for the investigation and treatment of patients with inherited human diseases
- a basic understanding of the scope and effect of genomics on treatments including horizon scanning of potential new targeted treatments for wider population

Course Structure

The online course lasts one calendar year and is a part time distance learning course. It consists of 6 modules per year, each of 6 weeks duration.

Module 1 - Principles of Medical Genetics and Genomics
Module 2 - Genetic Counselling
Module 3 - Genomics and Society
Module 4 - Practice of Clinical Genomics
Module 5 - Reproductive Genomics
Module 6 - Genomic Healthcare

Assessment

Online Diploma in Genomic Medicine and Healthcare

The course puts assessment at the heart of learning by using clinical scenarios to facilitate problem-solving, critical analysis and evidence-based care. The scenarios act as both the focus for learning and assessment thus embedding assessment within the learning process.

Each of the 6 modules have the same assessment format. Due to the online nature of the course, students are expected to login and participate in the course regularly throughout the module (ideally on a daily basis).

Students are split into groups of 10-15 students and are assigned a dedicated expert tutor who:

Facilitates clinical case discussions with the group.
Monitors, assesses and marks each student throughout the module.
Students use the skills gained during the lectures to engage with the different activities (see below).
Clinical case scenarios with case based discussion - 40%
Individual learning portfolio - 10%
Group/individual activity - 20%
Case based examination - 30%

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This course provides core training in the theoretical and practical aspects of medical parasitology, covering the protozoan and metazoan parasites of humans and the vectors which transmit them. Read more
This course provides core training in the theoretical and practical aspects of medical parasitology, covering the protozoan and metazoan parasites of humans and the vectors which transmit them. Students will gain specialised skills to enable them to pursue a career in research, control or teaching related to medical parasitology.

Graduates enter a range of global health fields ranging from diagnostics through to applied basic research and operational control to higher degree studies and academic/teaching-related positions.

The Patrick Buxton Memorial Medal and Prize is awarded to the best student of the year. Founded by relatives of Patrick Alfred Buxton, Professor in Entomology, who died in 1955.

- Full programme specification (pdf) (http://www.lshtm.ac.uk/edu/qualityassurance/mp_progspec.pdf)
- Intercalating this course (http://www.lshtm.ac.uk/study/intercalate)

Visit the website http://www.lshtm.ac.uk/study/masters/msmp.html

Additional Requirements

An additional preferred requirement for the MSc Parasitology is an interest in parasites of public health importance and disease transmission. Any student who does not meet the minimum entry requirement above but who has relevant professional experience may still be eligible for admission. Qualifications and experience will be assessed from the application.

Objectives

By the end of this course students should be able to demonstrate:

- detailed knowledge and understanding of the biology, life cycles, pathogenesis, and diagnosis of parasitic infections in humans and their relevance for human health and control

- detailed knowledge and understanding of the biology and strategies for control of the vectors and intermediate hosts of human parasites

- carry out practical laboratory identification of parasite stages both free and in tissues and diagnose infections

- specialised skills in: advanced diagnostic, molecular, immunological, genetic, chemotherapeutic, ecological and/or control aspects of the subject

- the ability to design a laboratory or field-based research project, and apply relevant research skills

- prepare a written report including a critical literature review of relevant scientific publications, and show competence in communicating scientific findings

Structure

Term 1:
There is a two-week orientation period that includes an introduction to studying at the School, sessions on key computing and study skills and an introduction to major groups of pathogens, followed by three compulsory core modules:

- Parasitology & Entomology
- Analysis & Design of Research Studies
- Critical Skills for Tropical Medicine

Recommended module: Molecular Biology

Sessions on basic computing, molecular biology and statistics are run throughout the term for all students.

Terms 2 and 3:
Students take a total of five modules, one from each timetable slot (Slot 1, Slot 2 etc.). Some modules can be taken only after consultation with the Course Director.

*Recommended modules

- Slot 1:
Epidemiology & Control of Malaria*
Molecular Biology & Recombinant DNA Techniques*
Advanced Immunology 1
Designing Disease Control Programmes in Developing Countries

- Slot 2:
Advanced Diagnostic Parasitology*
Advanced Immunology 2
Design & Analysis of Epidemiological Studies
Statistical Methods in Epidemiology

- Slot 3:
Vector Sampling, Identification & Incrimination*
Advanced Training in Molecular Biology
Spatial Epidemiology in Public Health
Tropical Environmental Health

- Slot 4:
Immunology of Parasitic Infection: Principles*
Molecular Biology Research Progress & Applications*
Vector Biology & Vector Parasite Interactions*
Epidemiology & Control of Communicable Diseases
Genetic Epidemiology

- Slot 5 :
Antimicrobial Chemotherapy*
Integrated Vector Management*
Molecular Cell Biology & Infection*
AIDS

Further details for the course modules - http://www.lshtm.ac.uk/study/currentstudents/studentinformation/msc_module_handbook/section2_coursedescriptions/tmpa.html

Residential Field Trip

There is a compulsory one week field course, after the Term 3 examinations, on vector and parasite sampling and identification methods.The cost of £630 is included in the field trip fee.

Project Report

During the summer months (July - August), students complete a research project, for submission by early September. This may be based on a critical review of an approved topic, analysis of a collection of results or a laboratory study.Students undertaking projects overseas will require additional funding of up to £1,500 to cover costs involved.

The majority of students who undertake projects abroad receive financial support for flights from the School's trust funds set up for this purpose.

Find out how to apply here - http://www.lshtm.ac.uk/study/masters/msmp.html#sixth

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We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments. Read more

We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments.

As a student you will be registered with a University research institute, for many this is the Institute for Cellular Medicine (ICM). You will be supported in your studies through a structured programme of supervision and training via our Faculty of Medical Sciences Graduate School.

We undertake the following areas of research and offer MPhil, PhD and MD supervision in:

Applied immunobiology (including organ and haematogenous stem cell transplantation)

Newcastle hosts one of the most comprehensive organ transplant programmes in the world. This clinical expertise has developed in parallel with the applied immunobiology and transplantation research group. We are investigating aspects of the immunology of autoimmune diseases and cancer therapy, in addition to transplant rejection. We have themes to understand the interplay of the inflammatory and anti-inflammatory responses by a variety of pathways, and how these can be manipulated for therapeutic purposes. Further research theme focusses on primary immunodeficiency diseases.

Dermatology

There is strong emphasis on the integration of clinical investigation with basic science. Our research include:

  • cell signalling in normal and diseased skin including mechanotransduction and response to ultraviolet radiation
  • dermatopharmacology including mechanisms of psoriatic plaque resolution in response to therapy
  • stem cell biology and gene therapy
  • regulation of apoptosis/autophagy
  • non-melanoma skin cancer/melanoma biology and therapy.

We also research the effects of UVR on the skin including mitochondrial DNA damage as a UV biomarker.

Diabetes

This area emphasises on translational research, linking clinical- and laboratory-based science. Key research include:

  • mechanisms of insulin action and glucose homeostasis
  • insulin secretion and pancreatic beta-cell function
  • diabetic complications
  • stem cell therapies
  • genetics and epidemiology of diabetes.

Diagnostic and therapeutic technologies

Focus is on applied research and aims to underpin future clinical applications. Technology-oriented and demand-driven research is conducted which relates directly to health priority areas such as:

  • bacterial infection
  • chronic liver failure
  • cardiovascular and degenerative diseases.

This research is sustained through extensive internal and external collaborations with leading UK and European academic and industrial groups, and has the ultimate goal of deploying next-generation diagnostic and therapeutic systems in the hospital and health-care environment.

Kidney disease

There is a number of research programmes into the genetics, immunology and physiology of kidney disease and kidney transplantation. We maintain close links between basic scientists and clinicians with many translational programmes of work, from the laboratory to first-in-man and phase III clinical trials. Specific areas:

  • haemolytic uraemic syndrome
  • renal inflammation and fibrosis
  • the immunology of transplant rejection
  • tubular disease
  • cystic kidney disease.

The liver

We have particular interests in:

  • primary biliary cirrhosis (epidemiology, immunobiology and genetics)
  • alcoholic and non-alcoholic fatty liver disease
  • fibrosis
  • the genetics of other autoimmune and viral liver diseases

Magnetic Resonance (MR), spectroscopy and imaging in clinical research

Novel non-invasive methodologies using magnetic resonance are developed and applied to clinical research. Our research falls into two categories:

  • MR physics projects involve development and testing of new MR techniques that make quantitative measurements of physiological properties using a safe, repeatable MR scan.
  • Clinical research projects involve the application of these novel biomarkers to investigation of human health and disease.

Our studies cover a broad range of topics (including diabetes, dementia, neuroscience, hepatology, cardiovascular, neuromuscular disease, metabolism, and respiratory research projects), but have a common theme of MR technical development and its application to clinical research.

Musculoskeletal disease (including auto-immune arthritis)

We focus on connective tissue diseases in three, overlapping research programmes. These programmes aim to understand:

  • what causes the destruction of joints (cell signalling, injury and repair)
  • how cells in the joints respond when tissue is lost (cellular interactions)
  • whether we can alter the immune system and ‘switch off’ auto-immune disease (targeted therapies and diagnostics)

This research theme links with other local, national and international centres of excellence and has close integration of basic and clinical researchers and hosts the only immunotherapy centre in the UK.

Pharmacogenomics (including complex disease genetics)

Genetic approaches to the individualisation of drug therapy, including anticoagulants and anti-cancer drugs, and in the genetics of diverse non-Mendelian diseases, from diabetes to periodontal disease, are a focus. A wide range of knowledge and experience in both genetics and clinical sciences is utilised, with access to high-throughput genotyping platforms.

Reproductive and vascular biology

Our scientists and clinicians use in situ cellular technologies and large-scale gene expression profiling to study the normal and pathophysiological remodelling of vascular and uteroplacental tissues. Novel approaches to cellular interactions have been developed using a unique human tissue resource. Our research themes include:

  • the regulation of trophoblast and uNk cells
  • transcriptional and post-translational features of uterine function
  • cardiac and vascular remodelling in pregnancy

We also have preclinical molecular biology projects in breast cancer research.

Respiratory disease

We conduct a broad range of research activities into acute and chronic lung diseases. As well as scientific studies into disease mechanisms, there is particular interest in translational medicine approaches to lung disease, studying human lung tissue and cells to explore potential for new treatments. Our current areas of research include:

  • acute lung injury - lung infections
  • chronic obstructive pulmonary disease
  • fibrotic disease of the lung, both before and after lung transplantation.

Pharmacology, Toxicology and Therapeutics

Our research projects are concerned with the harmful effects of chemicals, including prescribed drugs, and finding ways to prevent and minimise these effects. We are attempting to measure the effects of fairly small amounts of chemicals, to provide ways of giving early warning of the start of harmful effects. We also study the adverse side-effects of medicines, including how conditions such as liver disease and heart disease can develop in people taking medicines for completely different medical conditions. Our current interests include: environmental chemicals and organophosphate pesticides, warfarin, psychiatric drugs and anti-cancer drugs.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.



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The Pre-Masters in Biomedical Science (Graduate Diploma in Biomedical Science) provides a discipline-specific pathway (a pre-masters year) into the taught Biomedical Blood Science masters level programme. Read more

Overview

The Pre-Masters in Biomedical Science (Graduate Diploma in Biomedical Science) provides a discipline-specific pathway (a pre-masters year) into the taught Biomedical Blood Science masters level programme. It is a one-year full-time programme designed for both home and international students, with a background in life sciences, who wish to study at postgraduate level for the MSc in Biomedical Blood Science. The programme is open to science graduates who do not meet the academic criteria for a direct entry into the MSc. The MSc in Biomedical Blood Science is accredited by the Institute of Biomedical Science (IBMS). The IBMS is the professional body of Biomedical Scientists within the United Kingdom. The IBMS aims to promote and develop the role of Biomedical Science within healthcare to deliver the best possible service for patient care and safety.

See the website https://www.keele.ac.uk/pgtcourses/biomedicalsciencegraduatediploma/

Course Aims

The overall aim is to provide the students with the academic background necessary for the masters programme and to enable them to develop and practise the subject specific academic skills required for the intensive pace of study at masters level. The course also aims to allow international students to benefit from English language support that will help them to develop their academic English language skills.

Intended learning outcomes of the programme reflect what successful students should know, understand or to be able to do by the end of the programme. Programme specific learning outcomes are provided in the Programme Specification available by request; but, to summarise, the overarching course aims are as follows:

- To provide students with core knowledge, understanding and skills relevant to Biomedical Science

- To produce skilled and motivated graduates who are suitably prepared for the MSc in Biomedical Science and for further study.

- To cultivate interest in the biosciences, particularly at the cellular and molecular level, within a caring and intellectually stimulating environment.

- To get an accurate insight into the role of Biomedical Scientists in the diagnosis, treatment and monitoring of disease.

- To develop an understanding of the analytical, clinical and diagnostic aspects of Cellular Pathology, Clinical Biochemistry, Medical Microbiology, Blood Transfusion, Clinical Immunology and Haematology pathology laboratories.

- To promote the development of a range of key skills, for use in all areas where numeracy and an objective, scientific approach to problem-solving are valued.

- To provide students with a wide range of learning activities and a diverse assessment strategy in order to fully develop their employability and academic skills, ensuring both professional and academic attainment.

- To promote the development of critical thinking, autonomous learning, independent research and communication skills to help prepare the students for the MSc in Biomedical Blood Science and for a lifetime of continued professional development.

Course Content

All the modules in this one year programme are compulsory. The programme consists of a total of 90 credits made up of one 30 credit module and four 15 credit modules. An additional English module (English for Academic Purposes) will be offered for non-native English speakers if required. This module will not form part of the overall award, but successful completion is required for progression to the Masters programme.

Modules:
- Biomedical Science and Pathology (30 credits):
The module provides the student with the knowledge and understanding of the pathobiology of human disease associated with Cellular Pathology, Clinical Immunology, Haematology, Clinical Biochemistry, Medical Microbiology and Clinical Virology. It also examines the analytical and clinical functions of three more of the major departments of a modern hospital pathology laboratory, including Haematology, Clinical Pathology, Clinical Immunology, Blood Transfusion, Clinical Biochemistry and Medical Microbiology. In addition, the module will give an accurate insight into the role of Biomedical Scientists and how they assist clinicians in the diagnosis, treatment and monitoring of disease.

- Biochemistry Research Project (non-experimental) (15 credits):
This module aims to introduce students to some of the key non-experimental research skills that are routinely used by biochemists and biomedical scientists, such as in depth literature searching, analysis of experimental data and the use of a computer as tool for both research (bioinformatics) and dissemination of information (web page construction). The student will research the literature on a specific topic, using library and web based resources and will produce a written review. In addition, the student will either process and interpret some raw experimental data provided to them.

- Advances in Medicine (15 credits):
This module will describe and promote the understanding of advances in medicine that have impacted on diagnosis, treatment, prevention of a range of diseases. It will highlight fast emerging areas of research which are striving to improve diagnosis including nanotechnology and new biochemical tests in the fields of heart disease, cancer and fertility investigations which will potentially improve patient care.

- Clinical Pathology (15 credits):
The majority of staff that contribute to the module are employees of the University Hospital of North Staffordshire (UHNS). Students will benefit from lectures and expertise in Clinical Diagnostic Pathology, Pharmacology, Biochemistry, Genetics and Inflammatory Diseases. Students will gain an insight into how patients are managed, from their very first presentation at the UHNS, from the perspective of diagnosis and treatment. The course will cover both standardised testing options and the development of new diagnostic procedures with a particular emphasis on genetic and epigenetic aspects of disease. Students will also gain an appreciation of the cost benefit of particular routes for diagnosis and treatment and the importance of identifying false positive and false negative results. Finally, the students will have the opportunity to perform their own extensive literature review of a disease-related topic that is not covered by the lectures on the course.

- Case Studies in Biomedical Science (15 credits):
This module aims to give you an understanding of the UK health trends and the factors that affect these trends. Through clinical case studies and small group tutorials, you will explore why the UK has some of the highest incidences of certain diseases and conditions in Europe and consider what factors contribute to making them some of the most common and/or rising health problems faced by this country. This will include understanding the relevant socioeconomic factors as well as understanding the bioscience of the disease process and its diagnosis and management. You will also focus on what is being done by Government and the NHS to tackle these major health problems.

- English for Academic Purposes (EAP ):
For non-native English speakers if required

Teaching & Assessment

In addition to the lecture courses and tutorials, problem based learning (PBL) using clinical scenarios is used for at least one module. Students will also be given the opportunity to undertake an independent non-experimental research project, supervised and supported by a member of staff. Web-based learning using the University’s virtual learning environment (KLE) is also used to give students easy access to a wide range of resources and research tools, and as a platform for online discussions and quizzes. Students will be given many opportunities to become familiar with word processing, spreadsheets and graphics software as well as computer-based routes to access scientific literature.

All modules are assessed within the semester in which they are taught. Most contain elements of both ‘in-course’ assessment (in the form of laboratory reports, essays, posters) and formal examination, although some are examined by ‘in-course’ assessment alone.

Additional Costs

Apart from additional costs for text books, inter-library loans and potential overdue library fines we do not anticipate any additional costs for this post graduate programme.

Find information on Scholarships here - http://www.keele.ac.uk/studentfunding/bursariesscholarships/

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This course develops the careers of doctors whose interest is the practice of medicine in tropical and low- and middle-income countries. Read more
This course develops the careers of doctors whose interest is the practice of medicine in tropical and low- and middle-income countries. The course offers a wide choice of modules and provides training in clinical tropical medicine at the Hospital for Tropical Diseases.

The Diploma in Tropical Medicine & Hygiene (DTM&H):
All students going on the MSc will take the Diploma in Tropical Medicine & Hygiene. Students with a prior DTM&H, or holding 60 Masters level credits from the East African Diploma in Tropical Medicine & Hygiene may apply for exemption from Term 1 via accreditation of prior learning.

Careers

Graduates from this course have taken a wide variety of career paths including further research in epidemiology, parasite immunology; field research programmes or international organisations concerned with health care delivery in conflict settings or humanitarian crises; or returned to academic or medical positions in low- and middle-income countries.

Awards

The Frederick Murgatroyd Award is awarded each year for the best student of the year. Donated by Mrs Murgatroyd in memory of her husband, who held the Wellcome Chair of Clinical Tropical Medicine in 1950 and 1951.

- Full programme specification (pdf) (http://www.lshtm.ac.uk/edu/qualityassurance/tmih_progspec.pdf)

Visit the website http://www.lshtm.ac.uk/study/masters/mstmih.html

Objectives

By the end of this course students should be able to:

- understand and describe the causation, pathogenesis, clinical features, diagnosis, management, and control of the major parasitic, bacterial, and viral diseases of developing countries

- demonstrate knowledge and skills in diagnostic parasitology and other simple laboratory methods

- understand and apply basic epidemiological principles, including selecting appropriate study designs

- apply and interpret basic statistical tests for the analysis of quantitative data

- critically evaluate published literature in order to make appropriate clinical decisions

- communicate relevant medical knowledge to patients, health care professionals, colleagues and other groups

- understand the basic sciences underlying clinical and public health practice

Structure

Term 1:
All students follow the course for the DTM&H. Term 1 consists entirely of the DTM&H lectures, seminars, laboratory practical and clinical sessions, and is examined through the DTM&H examination and resulting in the award of the Diploma and 60 Master's level credits at the end of Term 1.

Terms 2 and 3:
Students take a total of five study modules, one from each timetable slot (Slot 1, Slot 2 etc.). Recognising that students have diverse backgrounds and experience, the course director considers requests to take any module within the School's portfolio, provided that this is appropriate for the student.

*Recommended modules

- Slot 1:
Clinical Infectious Diseases 1: Bacterial & Viral Diseases & Community Health in Developing Countries*
Clinical Virology*
Epidemiology & Control of Malaria*
Advanced Immunology 1
Childhood Eye Disease and Ocular Infection
Designing Disease Control Programmes in Developing Countries
Drugs, Alcohol and Tobacco
Economic Evaluation
Generalised Liner Models
Health Care Evaluation
Health Promotion Approaches and Methods
Maternal & Child Nutrition
Molecular Biology & Recombinant DNA Techniques
Research Design & Analysis
Sociological Approaches to Health
Study Design: Writing a Proposal

- Slot 2:
Clinical Infectious Diseases 2: Parasitic Diseases & Clinical Medicine*
Conflict and Health*
Design & Analysis of Epidemiological Studies*
Advanced Diagnostic Parasitology
Advanced Immunology 2
Clinical Bacteriology 1
Family Planning Programmes
Health Systems; History & Health
Molecular Virology; Non Communicable Eye Disease
Population, Poverty and Environment
Qualitative Methodologies
Statistical Methods in Epidemiology

- Slot 3:
Clinical Infectious Diseases 3: Bacterial & Viral Diseases & Community Health in Developing Countries*
Control of Sexually Transmitted Infections*
Advanced Training in Molecular Biology
Applied Communicable Disease Control
Clinical Immunology
Current Issues in Safe Motherhood & Perinatal Health
Epidemiology of Non-Communicable Diseases
Implementing Eye Care: Skills and Resources
Medical Anthropology and Public Health
Modelling & the Dynamics of Infectious Diseases
Nutrition in Emergencies
Organisational Management
Social Epidemiology
Spatial Epidemiology in Public Health
Tropical Environmental Health
Vector Sampling, Identification & Incrimination

- Slot 4:
Clinical Infectious Diseases 4: Parasitic Diseases & Clinical Medicine*
Epidemiology & Control of Communicable Diseases*
Ethics, Public Health & Human Rights*
Global Disability and Health*
Immunology of Parasitic Infection: Principles*
Analytical Models for Decision Making
Clinical Bacteriology 2
Design & Evaluation of Mental Health Programmes
Environmental Epidemiology
Evaluation of Public Health Interventions
Genetic Epidemiology
Globalisation & Health
Molecular Biology Research Progress & Applications
Nutrition Related Chronic Diseases
Population Dynamics & Projections
Reviewing the Literature
Sexual Health
Survival Analysis and Bayesian Statistics
Vector Biology & Vector Parasite Interactions

- Slot 5:
AIDS*
Antimicrobial Chemotherapy*
Mycology*
Advanced Statistical Methods in Epidemiology
Analysing Survey & Population Data
Applying Public Health Principles in Developing Countries
Environmental Health Policy
Integrated Vector Management
Integrating Module: Health Promotion
Molecular Cell Biology & Infection
Nutrition Programme Planning
Pathogen Genomics
Principles and Practice of Public Health

Further details for the course modules - http://www.lshtm.ac.uk/study/currentstudents/studentinformation/msc_module_handbook/section2_coursedescriptions/ttmi.html

Project Report:
During the summer months (July - August), students complete a research project in a subject of their choice, for submission by early September. Projects may involve writing up and analysing work carried out before coming to the School, a literature review, or a research study proposal. Some students gather data overseas or in the UK for analysis within the project. Such projects require early planning.

Students undertaking projects overseas will require additional funding of up to £1,500 to cover costs involved. The majority of students who undertake projects abroad receive financial support for flights from the School's trust funds set up for this purpose.

Find out how to apply here - http://www.lshtm.ac.uk/study/masters/mstmih.html#sixth

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This course, which uniquely combines forensic genetic and conservation genetic elements within one of the largest forensic science academic departments in the world, runs in conjunction with other well established and popular MSc courses. Read more
This course, which uniquely combines forensic genetic and conservation genetic elements within one of the largest forensic science academic departments in the world, runs in conjunction with other well established and popular MSc courses. Students will learn the fundamentals of molecular genetics, population genetics and phylogenetics that underpin the disciplines of forensic and conservation genetics and develop both theoretical knowledge and practical application.

Small cohort sizes will allow the use of a diverse range of assessments and the provision of considerable student support. Teaching will be carried out using a combination of lectures, tutorials, practicals, computer workshops and self-directed study. In addition to six taught modules, students will undertake a three-module research project which will develop laboratory and research skills. Depending on availability, students may also have an opportunity to visit and gain field experience at the Maasai Centre for Field Studies in Kenya.

LEARNING ENVIRONMENT AND ASSESSMENT

The forensic genetics group has dedicated pre and post-PCR laboratories housing an ABI3500, two ABI310 machines, an ABI7500 real-time PCR machine, a number of ABI2700 PCR machines, gel imaging systems, and several PCR cabinets. MSc students will carry out laboratory-based dissertation research projects within these well equipped modern laboratories. Research topics within the group are diverse, ranging from forensic genetics and human genetics, to wildlife forensics and forensic entomology. This will ensure that a wide choice of dissertation topics is available to our students. We also have a number of full-time and part-time MRes/MPhil/PhD students and an interest in research is actively encouraged and maintained throughout the year via seminars/ discussions.

The course will be delivered through lectures, tutorials, computer workshops, and practical classes, working independently or as part of a group. At least an equal amount of time should be spent in private study reading around the subject. Guided teaching and formal assessments on this course will enhance the development of a number of transferable skills such as the production of written case reports, formal presentations, active participation in discussions, ability to work to deadlines, computing skills, scientific analysis, adherence and development of laboratory protocols, and research methods.

Assessment is predominantly through coursework except for one module which is assessed by both examination and coursework. Coursework will include written essays, laboratory reports, case reports, presentations and in Part 3, a dissertation.

OPPORTUNITIES

Students graduating from this course will be well placed to undertake further research at the doctoral level or take up jobs in forensic/genetics/veterinary/diagnostic/wildlife protection laboratories.

Two of our graduates have taken on jobs as DNA analysts while a others have gone on to undertake further degrees or research towards a MPhil/PhD.

Depending on availability, students may have an opportunity to visit and gain field experience at the Maasai Centre for Field Studies in Kenya.

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This MSc gives students excellent postgraduate training, and leads to exciting careers in research, industry, the NHS and other clinical institutions. Read more

About the course

This MSc gives students excellent postgraduate training, and leads to exciting careers in research, industry, the NHS and other clinical institutions. Many of our graduates have also gone on to study bioscience at PhD level.

You’ll develop an in-depth knowledge of medical and molecular genetics, and receive clinical genetics training to prepare you for a research project in a modern research facility. You’ll have the chance to collaborate with top genetics research laboratories and clinical partners.

This MSc was developed in partnership with the Sheffield Diagnostic Genetics Service (NHS), which is a world-renowned clinical genetics facility. This relationship is unique to this course and gives you the opportunity to be taught by the Director of the Sheffield Diagnostic Genetics Service, Sheffield Children’s Hospital NHS Foundation Trust, 
and their Head of Pharmacogenetics.

Where your masters can take you

Our graduates work in health care, pharmaceuticals, food safety and production, brewing and agrochemicals. Many of our masters students go on to do a PhD then pursue a career in research; others have gained entry to the prestigious NHS Scientist Training Programme (STP).

An international reputation

The 2014 Research Excellence Framework (REF) ranks Sheffield No 1 for biomedical research and in the UK top five for biological sciences generally. We have regular seminars from distinguished experts, and our motivated staff undertake collaborative research ranging from biotechnology to medicine.

Teaching and assessment

Our masters courses give you a solid grounding in experimental science, with personal supervision and tutorials by experienced scientists, based in modern and well-equipped labs, leading on to a research project in which you design and conduct your own research. You will learn cutting edge science from research leaders, and gain practice in reading the scientific literature and writing reports. Assessment is based on a combination of coursework, project work, formal examinations and a dissertation.

Modules

Genome Stability and Genetic Change; Human Genetics I; Human Genetics II; Advanced Research Topics; Laboratory Techniques in Molecular Bioscience; Literature Review; Research Project.

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The need to develop new strategies to combat diseases remains a major global challenge. This degree aims to enhance your employability and prepare you to tackle this challenge. Read more

The need to develop new strategies to combat diseases remains a major global challenge. This degree aims to enhance your employability and prepare you to tackle this challenge.

We’ll give you advanced training in the mechanisms underpinning a spectrum of infectious and non-infectious diseases, including viral, bacterial and parasitic infections, cancer, neurodegeneration, cardiovascular disease and chromosomal abnormalities. You’ll also explore current and emerging diagnostic and treatment strategies.

You’ll learn about the latest molecular, genetic and cellular approaches being used to understand, diagnose and treat human disease, including traditional methods such as polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA), and novel methods involving genome and proteome analysis.

You’ll also have the opportunity to investigate the role of the immune system in the response to infection and disease, covering topics such as innate and adaptive immunity, allergy and immune evasion.

If you choose to study at Leeds, you’ll join a faculty ranked 6th in the UK for its research impact in the recent Research Excellence Framework (REF 2014), and you’ll graduate with the solid base of scientific knowledge and specialist skills highly valued by employers.

Course content

On this course you’ll gain an overview of a range of modern techniques and methodologies that underpin contemporary biomolecular sciences. You’ll investigate five topic areas: molecular biology, structural biology, cell imaging and flow cytometry, high throughput techniques and transgenic organisms.

You’ll also apply your knowledge to an extended practical investigation in the form of a laboratory-based project, involving practical training in a range of modern molecular biology and protein engineering techniques such as gene cloning, PCR, mutagenesis, protein expression, protein purification and analysis.

To help you to develop and specialise, you’ll get substantial subject-specific training through an independent research project in an area of infection, immunity or human disease.

You’ll also take specialist taught modules covering topics such as infectious and non-infectious disease, advanced immunology, medical diagnostics and treatment of infectious diseases and cancer.

If you have previous experience of immunology, you could opt to investigate the structure, regulation and development of the pharmaceutical manufacturing sector, or explore aspects of human toxicology. These could include the actions of toxicants on the cardiovascular, immune and nervous systems, kidneys, liver and lungs, genetic toxicology and chemical carcinogenesis, and the effects of chemicals on fetal development.

In the final part of the course you'll work on an independent laboratory-based research project related to your course options. You’ll receive extensive training in experimental design, the practical use of advanced techniques and technologies, data analysis and interpretation, and will be assigned a research project supervisor who will support and guide you through your project.

Course structure

These are typical modules/components studied and may change from time to time. Read more in our Terms and conditions.

Compulsory modules

  • Advanced Immunology 10 credits
  • Infectious & Non-infectious Diseases 10 credits
  • Practical Bioinformatics 10 credits
  • Medical Diagnostics 10 credits
  • MSc Bioscience Research Project Proposal 5 credits
  • Treatment of Infectious Disease and Cancer 10 credits
  • Research Planning and Scientific Communication 10 credits
  • Advanced Biomolecular Technologies 20 credits
  • Protein Engineering Laboratory Project 15 credits
  • Bioscience MSc Research Project 80 credits

For more information on typical modules, read Infection, Immunity and Human Disease MSc in the course catalogue

Learning and teaching

You’ll have access to the very best learning resources and academic support during your studies. We’ve been awarded a Gold rating in the Teaching Excellence Framework (TEF, 2017), demonstrating our commitment to delivering consistently outstanding teaching, learning and outcomes for our students.

Your learning will be heavily influenced by the University’s world-class research as well as our strong links with highly qualified professionals from industry, non-governmental organisations and charities.

You’ll experience a wide range of teaching methods including formal lectures, interactive workshops, problem-solving, practical classes and demonstrations.

Through your research project and specialist modules, you’ll receive substantial subject-specific training. Our teaching and assessment methods are designed to develop you into a scientist who is able to think independently, solve problems, communicate effectively and demonstrate a high level of practical ability.

Assessment

We use a variety of assessment methods: multiple-choice testing, practical work, data handling and problem solving exercises, group work, discussion groups (face-to-face and online), computer-based simulation, essays, posters and oral presentations.

Career opportunities

The strong research element of the Infection, Immunity and Human Disease MSc, along with the specialist and generic skills you develop, mean you’ll graduate equipped for a wide range of careers.

Our graduates work in a diverse range of areas, ranging from bioscience-related research through to scientific publication, teacher training, health and safety and pharmaceutical market research.

Links with industry

We have a proactive Industrial Advisory Board who advise us on what they look for in graduates and on employability-related skills within our programmes.

We collaborate with a wide range of organisations in the public and commercial sectors. Many of these are represented on our Industrial Advisory Board. They include:

  • GlaxoSmithKline
  • Ernst and Young
  • The Food and Environment Research Agency
  • The Health Protection Agency
  • MedImmune
  • Thermofisher Scientific
  • Hays Life Sciences
  • European Bioinformatics Institute
  • Smaller University spin-out companies, such as Lumora

Industrial research placements

Some of our partners offer MSc research projects in their organisations, allowing students to develop their commercial awareness and build their network of contacts.

Professional and career development

We take personal and career development very seriously. We have a proactive Industrial Advisory Board who advises us on what they look for in graduates and on employability related skills within our courses.

Our dedicated Employability and Professional Development Officer ensures that you are aware of events and opportunities to increase your employability. In addition, our Masters Career Development Programme will support you to:

  • explore career options and career planning
  • understand the PhD application process and optimise PhD application
  • learn how to use LinkedIn and other social media for effective networking and career opportunities
  • practice interviews for both job and PhD applications.


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