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Masters Degrees (Gene Therapy)

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This Master's degree in Cell and Gene Therapy provides an in-depth education in this cutting-edge and rapidly developing field. Read more
This Master's degree in Cell and Gene Therapy provides an in-depth education in this cutting-edge and rapidly developing field. It is delivered by scientists and clinicians researching, developing and testing new treatments for genetically inherited and acquired diseases using gene delivery technology, stem cell manipulation and DNA repair techniques.

Degree information

The degree covers all aspects of the subject, including basic biomedical science, molecular basis of disease, current and developing technologies and clinical applications. Students also receive vocational training in research methodology and statistics, how to perform a research project and complete a practical laboratory-based project.

Students undertake modules to the value of 180 credits.

The programme consists of four core modules (60 credits), four optional modules (60 credits) and a research dissertation (60 credits). A Postgraduate Diploma (120 credits, full-time nine months or flexible up to five years) is offered. A Postgraduate Certificate (60 credits, full-time 12 weeks, part-time nine months, or up to two years flexible) is offered.

Core modules
-Molecular Aspects of Cell and Gene Therapy
-Clinical Applications of Cell and Gene Therapy
-Research Methodology and Statistics
-Stem Cell and Tissue Repair

Research Methodology and Statistics is not a core module for the PG Certificate. Students of the PG Certificate can choose an optional module.

Optional modules
-Foundations of Biomedical Sciences
-Applied Genomics
-HIV Frontiers from Research to Clinics
-Molecular and Genetic Basis of Paediatric Disease
-Understanding Research and Critical Appraisal: Biomedicine
-Laboratory Methods in Biomedical Science
-Research Methodology and Statistics

Dissertation/report
All MSc students undertake an independent research project which culminates in a dissertation.

Teaching and learning
Teaching includes lectures, seminars, problem classes and tutorials. Assessment varies depending on the module, but includes written coursework, multiple-choice questions, written examinations, a practical analysis examination and the dissertation.

Careers

The majority of our graduates have gone on to secure PhD places. Please see our programme website to read testimonials from past students which include their destinations following graduation.

Employability
This novel programme aims to equip students for careers in research, education, medicine and business in academic, clinical and industrial settings. Examples of potential careers could include academic research and/or lecturing in a university or other higher education setting, conducting clinical trials as part of a team of clinicians, scientists and allied health professionals, monitoring and analysing the results of clinical trials as part of a clinical trials unit, developing new therapies or intellectual property in the pharmaceutical industry or other business ventures.

Why study this degree at UCL?

The Institute of Child Health (ICH), and its clinical partner Great Ormond Street Hospital (GOSH), is the largest centre in Europe devoted to clinical, basic research and post-graduate education in children's health, including haematopoietic stem cell transplantation (HSCT) and gene therapy.

The UCL School of Life & Medical Sciences (SLMS) has the largest concentration of clinicians and researchers active in cell and gene therapy research in Europe. This is reflected by the many groups conducting high-quality research and clinical trials in the field including researchers at the Institute of Child Health, the Division of Infection and Immunity, the Institute of Ophthalmology, the Institute for Women's Health, the Institute of Genetics and the Cancer Institute.

Keywords: Stem Cells, Therapy, Genomics, Regenerative Medicine, Gene Editing

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The Cancer MSc reflects the depth and breadth of research interests, from basic science to translational medicine, within the UCL Cancer Institute. Read more
The Cancer MSc reflects the depth and breadth of research interests, from basic science to translational medicine, within the UCL Cancer Institute. The programme, taught by research scientists and academic clinicians, provides students with an in-depth look at the biology behind the disease processes which lead to cancer.

Degree information

This programme offers a foundation in understanding cancer as a disease process and its associated therapies. Students learn about the approaches taken to predict, detect, monitor and treat cancer, alongside the cutting-edge research methods and techniques used to advance our understanding of this disease and design better treatment strategies.

Students undertake modules to the value of 180 credits. The programme consists of two core modules (60 credits), four specialist modules (60 credits) and a research project (60 credits). A Postgraduate Diploma (120 credits, full-time nine months) is offered. A Postgraduate Certificate (60 credits, full-time 12 weeks) is offered.

Core modules
-Basic Biology and Cancer Genetics
-Cancer Therapeutics

Specialist modules
-Behavioural Science and Cancer
-Biomarkers in Cancer
-Cancer Clinical Trials
-Haematological Malignancies and Gene Therapy

Dissertation/report
All MSc students undertake a laboratory project, clinical trials project or systems biology/informatics project, which culminates in a 10,000–12,000 word dissertation and an oral research presentation.

Teaching and learning
Students develop their knowledge and understanding of cancer through lectures, self-study, database mining, wet-lab based practicals, clinical trial evaluations, laboratory training, assigned reading and self-learning. Each taught module is assessed by an unseen written examination and/or coursework. The research project is assessed by the dissertation (75%) and oral presentation (25%).

Careers

The knowledge and skills developed will be suitable for those in an industrial or healthcare setting, as well as those individuals contemplating a PhD or medical studies in cancer.

Top career destinations for this degree:
-Research Technician, NHS Imperial College Healthcare NHS Trust
-Cancer and Genetics, ETH Zurich
-PhD Cancer Research, University of New South Wales (UNSW)
-Clincial Trial Project Manager, Beijing Lawke Health Laboratory Inc.
-Research Scientist, SporeGen

Employability
Skills include critical evaluation of scientific literature, experimental planning and design interpretation of data and results, presentation/public speaking skills, time management, working with a team, working independently and writing for various audiences.

Why study this degree at UCL?

UCL is one of Europe's largest and most productive centres of biomedical science, with an international reputation for leading basic, translational and clinical cancer research.

The UCL Cancer Institute brings together scientists from various disciplines to synergise multidisciplinary research into cancer, whose particular areas of expertise include: the biology of leukaemia, the infectious causes of cancer, the design of drugs that interact with DNA, antibody-directed therapies, the molecular pathology of cancer, signalling pathways in cancer, epigenetic changes in cancer, gene therapy, cancer stem cell biology, early phase clinical trials, and national and international clinical trials in solid tumours and blood cancers.

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This comprehensive programme is intended for professionals specialising in paediatrics and child health and is based at the Institute of Child Health, which sits in a unique position in UK paediatrics because of its strong links to Great Ormond Street Hospital for Children and UCL. Read more
This comprehensive programme is intended for professionals specialising in paediatrics and child health and is based at the Institute of Child Health, which sits in a unique position in UK paediatrics because of its strong links to Great Ormond Street Hospital for Children and UCL.

Degree information

Students on this pathway gain an understanding of the principles of evidence-based paediatrics, and of the impact of molecular genetics on diagnosis and management of the child and family. They will build an awareness of current and future developments in paediatric medicine and child health and gain the skills necessary to critically appraise practice and policy, and undertake independent research if the full MSc is taken.

Students undertake modules to the value of 180 credits. The programme consists of four core modules (60 credits), four optional modules (60 credits) and a dissertation/report (60 credits). A Postgraduate Diploma (120 credits, full-time 9 months, flexible 2-5 years) is offered. The programme consists of four core modules (60 credits) and four optional modules (60 credits). A Postgraduate Certificate (60 credits, part-time 1 year, flexible 1-2) is offered. The programme consists of four core modules (60 credits).

Core modules
-Evidence-based Child Health
-Research Methodology and Statistics

Students must also choose at least two further core modules from the following:
-Molecular Biology of Normal Development and Birth Defects
-Molecular and Clinical Aspects of Childhood Cancers
-Clinical Genomics, Genetics and Rare Diseases

Please note: those modules not taken as core will still be available as options

Optional modules - students must take at least two modules from those available across the other pathways of the Paediatrics and Child Health MSc, with the following modules particularly recommended for students in this area:
-Stem Cells and Tissue Repair
-Molecular Aspects of Cell and Gene Therapy
-Clinical Applications of Cell and Gene Therapy
-Applied Genomics

Dissertation/report
All students undertake an independent research project which culminates in a dissertation of 10,000 words.

Teaching and learning
The programme is delivered through a combination of lectures, seminars, tutorials and research project supervision. Assessment is through a combination of multiple choice questions and short answer questions, essays, posters, presentations, reflective portfolios, critical appraisal of the literature and, for the full MSc, a dissertation and oral presentation.

Careers

The programme provides an ideal foundation for further doctoral research in this field and/or a career in research and evidence-based practice in paediatrics.

Employability
The first cohort of students on the Paediatrics and Child Health: Molecular and Genomic Paediatrics MSc will graduate in 2016, therefore no information on graduate destinations is currently available.

Why study this degree at UCL?

The Institute of Child Health pursues an integrated, multidisciplinary approach to enhance understanding, diagnosis, therapy and prevention of childhood diseases. Our research and our educational portfolio covers a broad range of paediatric issues, from molecular genetics to population health sciences, and our structure facilitates interdisciplinary work and follows flexibility for the development of new areas of investigation.

Our close relationship with the Great Ormond Street Hospital for Children means that much of our research and teaching is combined.

Students benefit from excellent facilities in both laboratory and non-laboratory subjects.

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Designed to appeal to both clinical and basic scientists, the course provides a comprehensive, theoretical and practical training using state-of-the-art techniques in molecular and cellular biology as applied to medicine. Read more
Designed to appeal to both clinical and basic scientists, the course provides a comprehensive, theoretical and practical training using state-of-the-art techniques in molecular and cellular biology as applied to medicine.

The practice of clinical medicine is currently being revolutionised by rapid and extraordinary technological advances in molecular biology in areas such as gene discovery, cancer, inherited diseases and gene therapy.

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This Clinical Pharmacology degree programme offers focused training which integrates basic and clinical sciences, and equips students with the essential skills required to function effectively as a clinical pharmacologist in the 21st century. Read more
This Clinical Pharmacology degree programme offers focused training which integrates basic and clinical sciences, and equips students with the essential skills required to function effectively as a clinical pharmacologist in the 21st century. As a student on the MSc Clinical Pharmacology programme, you will acquire core skills, enabling an appreciation of how to apply clinical pharmacological, regulatory and ethical principles to the optimisation of therapeutic practice and clinical research. Crucially, in addition to a firm grasp of the principles of molecular pharmacology, you will also gain foundational knowledge in the emerging science of pharmacogenomics and personalised medicine.

Why this programme

◾This Clinical Pharmacology MSc is one of only a few UK postgraduate programmes that cover clinical pharmacology in sufficient detail to allow you to make an informed choice about pursuing clinical pharmacology as a career.
◾You will learn the basics of molecular genetics and population genetics as applied to pharmacogenetics and gene therapy.
◾You will have the opportunity to gain hands-on experience in molecular methods and analysis along with critical interpretation of genomic literature. This will enable you to analyse, synthesise and formulate an action plan for personalised patient care.
◾You will gain the knowledge and experience necessary to engage in and contribute to discussions about therapeutic issues in the commercial and academic research environments. As part of the MSc Clinical Pharmacology degree, you will undertake your own research project under expert supervision, which will allow you to consolidate your knowledge and apply the skills you have acquired.
◾At every stage of the MSc Clinical Pharmacology you will benefit from the close involvement of clinical academics and visiting lecturers from the pharmaceutical industry and national drug regulatory bodies: the programme is specifically designed to prepare graduate for future senior roles within the pharmaceutical medicine. Guest lecturers have recently included staff from Pfizer, Servier, Johnson & Johnson and the Scottish Medicines Consortium.

Programme structure

You will attend lectures, seminars and tutorials and take part in lab, project and team work.

Core courses
◾Principles of Pharmacology
◾Drug Disposition
◾Pharmaceutical Medicine
◾Topics in Therapeutics – General Topics and Cardiovascular Drugs
◾Topics in Therapeutics – Commonly Used Drugs
◾Medical Statistics 1
◾Medical Statistics 2
◾Pharmacogenomics & Molecular Medicine – Fundamentals of Molecular Medicine
◾Pharmacogenomics & Molecular Medicine – Applied Pharmacogenomics & Molecular Medicine

In addition you will undertake a dissertation/project.

Career prospects

Career opportunities include positions in academia, health care and the pharmaceutical industry; returning to more advanced positions within a previous clinical environment (eg pharmacicts, clinicians); and PhD study.

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The science of human genetics has been transformed in the past decade. Following the sequencing of the entire human genome, a wealth of resources is now available to researchers aiming to identify the genetic variants that influence human health. Read more
The science of human genetics has been transformed in the past decade. Following the sequencing of the entire human genome, a wealth of resources is now available to researchers aiming to identify the genetic variants that influence human health. These findings will shed light on the underlying molecular pathology of many diseases that are poorly understood at present, eventually paving the way for novel treatment and prevention strategies. The speed at which these discoveries are being made is accelerating, and it is likely that molecular genetics will soon underpin much of modern medicine.

Career Pathways:
The MSc in Human Molecular Genetics programme is designed to prepare you for a genetics research career, either in human gene function and genetic disease, or molecular approaches to diagnosis and health care biotechnology. It provides a broad grounding in Human Genetics, with emphasis on molecular aspects, to give a solid basis for subsequent academic or industrial research, or for entry to NHS Genetics training. Approximately 40% of our students go on to do a PhD, 40% become research assistants/associates, while others go on to jobs in industry or further studies (bioinformatics/computing medicine). One or two students every year enter the NHS in clinical genetics training posts.

Programme Structure:
You will study the fundamentals of human and molecular genetics, models of inheritance for rare and common/ complex polygenic diseases, cytogenetics, analytical methods in human genetics and genomics, animal models and transgenesis, gene therapy, epigenetics, cancer genetics and an introduction to clinical genetics and genetic counselling services.

There are four weeks of intensive laboratory practical sessions, as well as computer science practicals applied to problems in genetics, genomics and bioinformatics, regular research seminars on site, student seminar and journal presentations, study group activities and a six-month full-time research project in the summer.

The programme is based on an average 20 hours contact time per week. This will vary between 15 hours in most weeks and approximately 40 hours during intensive practicals and projects. Private study time is included within the schedule: you are expected to contribute an additional 10-15 hours private study per week to the course. We do not recommend you try to support yourself by taking a part-time employment whilst studying as your work may suffer.

Assessment:
There are 3 x 3-hour written papers in late February, coursework assessments (poster presentation, analytical methods in genetics, oral presentation), a project report and a viva examination in September.

Programme Location:
The programme is primarily based at Hammersmith Campus in West London although some teaching modules are held at St Mary's Campus and the Northwick Park Campus.

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There is a separate entry on admission to the P.Grad.Dip. in Molecular Medicine. Read more
There is a separate entry on admission to the P.Grad.Dip. in Molecular Medicine.

This course aims to give participants an indepth understanding of the emerging field of molecular medicine which draws together developments in molecular and cellular biology to describe disease processes at a functional level - that of molecular interactions.

The course aims to provide students with an understanding of the molecular basis of human disease and its implications for the practice of clinical medicine and research in the life sciences. The course will ensure that students from all disciplines have the skills necessary to conduct research and critically evaluate the scientific and medical literature.

The course includes lectures on cellular biology and molecular genetics as they apply generally to normal cell and tissue function and to disease processes. Modules on molecular signalling and therapeutics, bioinformatics and ethical-legal aspects of the discipline are included, as well as literature reviews, laboratory practicals and a laboratory project.

The course is available in a one-year, full-time and a two-year, part-time format. It consists of lectures on cellular biology and molecular genetics as they apply generally to normal cell and tissue function and more specifically to disease processes such as cancer, immune dysfunction, and diseases with an inherited component. The course content includes molecular signalling and therapeutics, molecular and population genetics, nanoscience, and high content cell analysis. There is a core, 'Research Skills' module which encompasses bioinformatics and ethical-legal aspects of the emerging discipline, literature reviews, and laboratory practicals in basic molecular and cellular techniques. Candidates will complete a laboratory project of three months (full-time) or six months (part-time) duration. Candidates must also complete the taught module, Molecular Mechanisms of Human Disease I. This course provides the applicant with state-of-the-art information and critical analysis of: The human genome at a molecular level, the integration of molecular and cellular biology in relation to human diseases; the molecular basis of human genetic disease; the molecular interactions between microbiological pathogens and the human host; the technology currently employed in researching molecular medicine; the molecular basis of common human inflammatory diseases and malignancies; the utilisation of knowledge on the molecular basis of human disease in planning and design of novel therapies, using pharmacological agents or gene therapy; the ethical and legal aspects of molecular medicine as it impinges on clinical practice. You will also gain a working appreciation of molecular and cellular biology at the practical level and development of the ability to perform independent research with the ability to apply bioinformatic and computational techniques in medical and biological research, and information retrieval. The student is examined on the basis of a submitted critical literature review essay, a written examination, assessment of laboratory practicals and the writing of a dissertation based on a research project. Candidates from health science (medical, dental, veterinary), biological science and other science disciplines (e.g. chemical or pharmacy), are invited to apply.

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Are you a recent graduate, scientist, engineer or manager looking to develop your professional skills in multidisciplinary biotechnology and eager for a future in related sectors? The MSc in Biotechnology,. Read more
Are you a recent graduate, scientist, engineer or manager looking to develop your professional skills in multidisciplinary biotechnology and eager for a future in related sectors? The MSc in Biotechnology,
Bioprocessing and Business Management opens the door to these opportunities.

The course is delivered in partnership with our industry partners and Warwick Business School. During your studies you’ll develop a new sense of business acumen and gain in-depth knowledge of the underlying science and processing technologies. You’ll have access to specialised language classes, as well as a personal mentor who will help to improve your academic writing.

When you graduate, you’ll be ready to enter managerial and academic roles in several sectors, including the pharmaceutical industry, whether in large multinational companies or small to medium-sized enterprises.

Course structure

The course is a full time, twelve month taught programme with modular content, based around three strands:-
-Business Management
-Biotechnology & Molecular Biology
-Bioprocessing

The course programme focuses on:
-Manufacture of biochemicals, pharmaceuticals, devices and materials
-Genetic engineering and the fundamentals of biotechnology
-Business management, economics and finance
-Marketing management
-Commercialisation of products, IP
-Food, biotechnology and microbiological processing
-Fuels and energy
-Industries based on renewable and sustainable resources
-Production technologies
-Plant design and economic analysis

Students will be required to complete nine core modules. They must also select a further three elective modules. Teaching will be by interactive lectures, short question & answer sessions and small group interactive workshops/tutorials. Individual and team learning will be used for case study analysis.

All students will be required to undertake a project dissertation. Students will be encouraged to propose their own project title (selection subject to availability of an appropriate supervisor) although a range of potential titles will be offered. Projects will be non-laboratory based and generally undertaken at the University of Warwick under the supervision of an approved tutor.

Core Modules

-The fundamentals of biotechnology
-Molecular biology and genetic engineering
-Biochemical engineering
-Bioproduct plant design and economic analysis
-Business strategy
-Accounting and financial management
-Marketing management
-Entrepreneurship & commercialisation
-Biopharmaceutical product & clinical development
-Project

Elective Modules

(Availability dependent on demand)
-Microbiomics & metagenomics
-Environmental protection, risk assessment and safety
-Impact of biotechnology on the use of natural resources
-Fundamental principles of drug discovery
-E-business: Technology and management
-Chemotherapy of infectious disease
-Vaccines and gene therapy
-Laboratory Skills

Assessment

One third of the final mark will be derived from the project dissertation.

Two thirds of the final mark will be derived from assessments of the 9 core and 3 elective modules. Modules will be assessed by means of a combination of written course work, individual/group seminar presentations and a multi-choice or short answer examination. These assessments will take place during or shortly after completion of each module.

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Regenerative Medicine aims to generate therapeutics for repair and regeneration of damaged and diseased organs. These therapeutics are based on stem cells, gene therapy and engineered tissues. Read more
Regenerative Medicine aims to generate therapeutics for repair and regeneration of damaged and diseased organs. These therapeutics are based on stem cells, gene therapy and engineered tissues.
The M.Sc. in Regenerative Medicine at National University of Ireland in Galway, aims to provide students with the skills necessary for a career in this emerging discipline or within other areas of biomedical research. Taught modules will address the science behind regenerative medicine, its application to human disease and its importance to modern society. Students will then undertake a laboratory-based individual research project for four-5 months.
For more information see http://www.nuigalway.ie/courses/taught-postgraduate-courses/regenerative-medicine.html and http://www.remedi.ie/education/taught-msc-regenerative-medicine-0

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Cardiovascular disease is projected to remain the single leading cause of death over the next two decades, accountable for considerable disability and reduction in quality of life. Read more
Cardiovascular disease is projected to remain the single leading cause of death over the next two decades, accountable for considerable disability and reduction in quality of life. This Masters in Cardiovascular Sciences will include specialist training in the epidemiological nature of the disease, in combination with analysis of the cellular and molecular mechanisms that underlie its development.

Why this programme

◾This course is provided by world leading experts in the BHF Glasgow Cardiovascular Research Centre. Cardiovascular Medicine at Glasgow is rated in the UK’s top ten and has a research grant income of £50M.
◾Research for the MSc in Cardiovascular Sciences is supported by the BHF, MRC, Wellcome Trust, CSO, BBSRC and the European Commission.
◾You will undertake a research project with an established cardiovascular researcher.
◾This course is provided by world leading experts in the BHF Glasgow Cardiovascular Research Centre.
◾The Cardiovascular Science Degree has a modular based course containing taught elements, tutorial sessions, critical review sessions and hands-on demonstration of current laboratory techniques.
◾Tailored laboratory projects to suit student’s expertise and interests.
◾If you are a science or medicine graduate looking to gain knowledge and new skills in the field of cardiovascular medicine, this programme is designed for you.
◾You will have the opportunity to acquire and integrate a knowledge base in many new techniques for research in clinical cardiovascular medicine, including established risk factor measurements, novel imaging techniques, gene therapy, stem cells and the evolving genomics and proteomics fields.
◾Cardiovascular science is a priority area for research funding, in recognition of the fact that new, improved treatments are required and that these can only arise through better understanding of its development. The University of Glasgow has a world-renowned reputation for expertise in cardiovascular research and education.
◾Research is supported by the BHF, MRC, Wellcome Trust, CSO, BBSRC and the European Commission.
◾Opportunities exist at Glasgow University to continue to PhD Studies.

Programme structure

In addition to the taught courses you will take part in student-led critical review sessions where you will provide a critical appraisal of a scientific research paper taken from current literature.

You will also take part in an introductory session on how to review a scientific paper, designed to give you experience of reading, summarising and presenting the findings of a scientific publication in a critical manner.

Core courses
◾Clinical aspects of cardiovascular disease
◾Established and novel research techniques
◾Evidence based research in medicine
◾Medical statistics
◾Topics in therapeutics - general topics and cardiovascular disease
◾Topics in therapeutics - commonly used drugs
◾Pharmacogenomic and molecular medicine - fundamentals of molecular medicine
◾Pharmacogenomic and molecular medicine - applied pharamcogenomics and molecular medicine

Optional courses
◾Basic science diabetes and vascular disease
◾Clinical and research audit

In addition you will undertake a dissertation/project supervised by an established cardiovascular researcher.

Career prospects

Successful graduates will emerge equipped with the skills necessary for a career in the highly competitive field of cardiovascular research. Career opportunities include education, clinical translational cardiovascular research, public health bodies or commercial industrial research in the field of cardiovascular medicine. Students who have completed course are currently employed in NHS, PhD programmes, academia and industry.

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We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments. Read more

We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments.

As a student you will be registered with a University research institute, for many this is the Institute for Cellular Medicine (ICM). You will be supported in your studies through a structured programme of supervision and training via our Faculty of Medical Sciences Graduate School.

We undertake the following areas of research and offer MPhil, PhD and MD supervision in:

Applied immunobiology (including organ and haematogenous stem cell transplantation)

Newcastle hosts one of the most comprehensive organ transplant programmes in the world. This clinical expertise has developed in parallel with the applied immunobiology and transplantation research group. We are investigating aspects of the immunology of autoimmune diseases and cancer therapy, in addition to transplant rejection. We have themes to understand the interplay of the inflammatory and anti-inflammatory responses by a variety of pathways, and how these can be manipulated for therapeutic purposes. Further research theme focusses on primary immunodeficiency diseases.

Dermatology

There is strong emphasis on the integration of clinical investigation with basic science. Our research include:

  • cell signalling in normal and diseased skin including mechanotransduction and response to ultraviolet radiation
  • dermatopharmacology including mechanisms of psoriatic plaque resolution in response to therapy
  • stem cell biology and gene therapy
  • regulation of apoptosis/autophagy
  • non-melanoma skin cancer/melanoma biology and therapy.

We also research the effects of UVR on the skin including mitochondrial DNA damage as a UV biomarker.

Diabetes

This area emphasises on translational research, linking clinical- and laboratory-based science. Key research include:

  • mechanisms of insulin action and glucose homeostasis
  • insulin secretion and pancreatic beta-cell function
  • diabetic complications
  • stem cell therapies
  • genetics and epidemiology of diabetes.

Diagnostic and therapeutic technologies

Focus is on applied research and aims to underpin future clinical applications. Technology-oriented and demand-driven research is conducted which relates directly to health priority areas such as:

  • bacterial infection
  • chronic liver failure
  • cardiovascular and degenerative diseases.

This research is sustained through extensive internal and external collaborations with leading UK and European academic and industrial groups, and has the ultimate goal of deploying next-generation diagnostic and therapeutic systems in the hospital and health-care environment.

Kidney disease

There is a number of research programmes into the genetics, immunology and physiology of kidney disease and kidney transplantation. We maintain close links between basic scientists and clinicians with many translational programmes of work, from the laboratory to first-in-man and phase III clinical trials. Specific areas:

  • haemolytic uraemic syndrome
  • renal inflammation and fibrosis
  • the immunology of transplant rejection
  • tubular disease
  • cystic kidney disease.

The liver

We have particular interests in:

  • primary biliary cirrhosis (epidemiology, immunobiology and genetics)
  • alcoholic and non-alcoholic fatty liver disease
  • fibrosis
  • the genetics of other autoimmune and viral liver diseases

Magnetic Resonance (MR), spectroscopy and imaging in clinical research

Novel non-invasive methodologies using magnetic resonance are developed and applied to clinical research. Our research falls into two categories:

  • MR physics projects involve development and testing of new MR techniques that make quantitative measurements of physiological properties using a safe, repeatable MR scan.
  • Clinical research projects involve the application of these novel biomarkers to investigation of human health and disease.

Our studies cover a broad range of topics (including diabetes, dementia, neuroscience, hepatology, cardiovascular, neuromuscular disease, metabolism, and respiratory research projects), but have a common theme of MR technical development and its application to clinical research.

Musculoskeletal disease (including auto-immune arthritis)

We focus on connective tissue diseases in three, overlapping research programmes. These programmes aim to understand:

  • what causes the destruction of joints (cell signalling, injury and repair)
  • how cells in the joints respond when tissue is lost (cellular interactions)
  • whether we can alter the immune system and ‘switch off’ auto-immune disease (targeted therapies and diagnostics)

This research theme links with other local, national and international centres of excellence and has close integration of basic and clinical researchers and hosts the only immunotherapy centre in the UK.

Pharmacogenomics (including complex disease genetics)

Genetic approaches to the individualisation of drug therapy, including anticoagulants and anti-cancer drugs, and in the genetics of diverse non-Mendelian diseases, from diabetes to periodontal disease, are a focus. A wide range of knowledge and experience in both genetics and clinical sciences is utilised, with access to high-throughput genotyping platforms.

Reproductive and vascular biology

Our scientists and clinicians use in situ cellular technologies and large-scale gene expression profiling to study the normal and pathophysiological remodelling of vascular and uteroplacental tissues. Novel approaches to cellular interactions have been developed using a unique human tissue resource. Our research themes include:

  • the regulation of trophoblast and uNk cells
  • transcriptional and post-translational features of uterine function
  • cardiac and vascular remodelling in pregnancy

We also have preclinical molecular biology projects in breast cancer research.

Respiratory disease

We conduct a broad range of research activities into acute and chronic lung diseases. As well as scientific studies into disease mechanisms, there is particular interest in translational medicine approaches to lung disease, studying human lung tissue and cells to explore potential for new treatments. Our current areas of research include:

  • acute lung injury - lung infections
  • chronic obstructive pulmonary disease
  • fibrotic disease of the lung, both before and after lung transplantation.

Pharmacology, Toxicology and Therapeutics

Our research projects are concerned with the harmful effects of chemicals, including prescribed drugs, and finding ways to prevent and minimise these effects. We are attempting to measure the effects of fairly small amounts of chemicals, to provide ways of giving early warning of the start of harmful effects. We also study the adverse side-effects of medicines, including how conditions such as liver disease and heart disease can develop in people taking medicines for completely different medical conditions. Our current interests include: environmental chemicals and organophosphate pesticides, warfarin, psychiatric drugs and anti-cancer drugs.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.



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This is a multidisciplinary degree that brings together aspects of chemistry, biology and cell biology. The modules are carefully tailored to cover the knowledge in key fields such as. Read more

This is a multidisciplinary degree that brings together aspects of chemistry, biology and cell biology. The modules are carefully tailored to cover the knowledge in key fields such as:

  • Gene therapy
  • Drug design
  • Genomics
  • Proteomics
  • Genetic engineering for plants
  • Animals and micro-organisms
  • Bioinformatics.

This degree produces graduates with a critical, analytical and flexible approach to problem solving, enhancing laboratory and professional competence and enabling students to work independently and use their initiative in solving the diverse problems they encounter.

The programme helps you to obtain a creative attitude to the development and manufacture of biotechnology products. The intention is that skills and knowledge can be more readily transferred to professional activities.

The aims of the programme are:

  • To provide students with subject-specific knowledge, as well as a critical, analytical and flexible approach to problem solving in the field of biotechnology
  • To provide students with enhanced practical and professional skills and thus prepare them effectively for professional employment or doctoral studies in the field of biotechnology
  • To enable students to work independently and use initiative to solve the diverse problems they may encounter
  • To instil a critical awareness of advances at the forefront of biotechnology.

Science - General

We offer a range of sciences programmes from biotechnology to formulation science. Whatever you choose to study you will be taught by experienced staff in state-of-the-art laboratories and gain the skills you need to succeed in your chosen field. Employability is central to all our programmes and you will benefit from our strong links with employers, industry work placements and professional accreditations.

What you'll study

Full time

- Year 1

Students are required to study the following compulsory courses.

Biotechnology Research Projects (60 credits)

Bioinformatics (30 credits)

Research Methods and Data management (30 credits)

English Language Support (for Postgraduate students in the Faculty of Engineering and Science)

Applied Molecular Biology (30 credits)

Students are required to choose 1 course from this list of options.

Biotechnology and Transgenic Crops (30 credits)

Pharmaceutical Biotechnology (30 credits)

Fees and finance

Your time at university should be enjoyable and rewarding, and it is important that it is not spoilt by unnecessary financial worries. We recommend that you spend time planning your finances, both before coming to university and while you are here. We can offer advice on living costs and budgeting, as well as on awards, allowances and loans.

Find out more about our fees and the support available to you at our:

- Postgraduate finance pages (https://www.gre.ac.uk/study/finance/postgraduate)

- International students' finance pages (http://www2.gre.ac.uk/students/international/international-students/finance)

Assessment

Students are assessed through:

  • Coursework
  • Examinations
  • Presentations
  • Thesis
  • Online assessment.

Teaching and learning

This programme involves a series of lectures, seminars and workshops. Case studies will provide you with exposure to up-to-date problems and enhance your problem solving and team-work in a way that simulates an industrial setting. A research project in a well equipped department led by staff with a diversity of research experience will give you the opportunity to carry out novel research and enhance your practical skills, analytical thinking and independence.

Career options

Biotechnology and pharmaceutical industries, intellectual property industry (IP), academics, bio-informatics/IT, health services, research and higher degrees (PhD).

Find out how to apply here - https://www2.gre.ac.uk/study/apply



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Haematologists specialise in disorders of the blood and blood-forming tissues, and their contribution to patient care is fundamental and wide-ranging. Read more
Haematologists specialise in disorders of the blood and blood-forming tissues, and their contribution to patient care is fundamental and wide-ranging. Whether you’re analysing data from patients' samples, matching donated blood with someone who needs a transfusion or researching cures for blood cancers, your work will improve and save countless lives.


Why study MSc Biomedical Science -Haematology and Transfusion Science at Middlesex?

Our Biomedical Science courses have a burgeoning international reputation, due to our world-class research in areas including biomarkers, public health and bio modelling. Our Centre for Investigative and Diagnostic Oncology has pioneered techniques for cancer diagnosis and treatment, and the Haematology department is very active in research into blood cancers, HIV and AIDS.

Our course has a strong practical element, with an emphasis on developing laboratory skills and gaining hands-on experience of diagnostic techniques. Our teaching and research facilities surpass those at some UK medical schools, with £3 million specialist labs equipped with the most up-to-date technology- the perfect place to work on your own research project. You’ll learn to use cutting-edge equipment, including MALDI-TOF mass spectrometers and flow cyto meters; we have a molecular biology laboratory for techniques such as DNA sequencing, real-time PCR, electrophoresis and HPLC, fully-equipped proteomics facilities, a microbiology lab and an incredibly modern cell culture facility.

Course highlights

- Course leader Dr Colin Casimir is famed for his research into the biology of haemopoietic stem cells and gene therapy for haematologic conditions. He is the holder of a number of international patents, and his research has been published in top international journals, including the British Journal of Haematology.
- Other teaching staff include Dr Stephen Butler, a world expert on cancer biomarkers and reproductive biochemistry; Dr Ajit Shah, a former principal scientist at GlaxoSmithKline; and Dr Lucy Ghali, an expert in immunohistochemistry. Guest lecturers include Peter Gregory, haematology services manager at Barnet and Chase Farm Hospitals Trust.
- Our staff are supportive and hands-on – ever-ready with advice on your studies, they’re also known for their strong pastoral care and for going the extra mile for their students. All our teaching staff are involved in research.
- The course is accredited by the Institute of Biomedical Science, so on graduation you’ll have fulfilled the academic requirement for Licentiate membership of the institute; you can apply for student membership while you study.
- We work with London hospitals and NHS laboratories to ensure you’re fully versed in both the latest practice and the latest research. - You’ll visit diagnostic laboratories and of course, our location gives you easy access to the British Library, the Science Museum, the Royal Institution and more.

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1. Big Challenges being addressed by this programme – motivation. Human health and quality of life is one of the most critical challenges facing humanity. Read more

About the Course

1. Big Challenges being addressed by this programme – motivation

• Human health and quality of life is one of the most critical challenges facing humanity.
• The challenge is all the greater due to a rapidly increasing and rapidly aging global population that now exceeds 7 billion.
• Biomedical Engineering addresses these issues directly, with engineers innovating, analysing, designing and manufacturing new medical implants, devices and therapies for the treatment of disease, injuries and conditions of the human body, to restore health and improve quality of life.
• CNN lists Biomedical Engineering as No. 1 in the “Best Jobs in America” 2013.

2. Programme objectives & purpose

The objective of the programme is to generate graduates with a sound grounding in engineering fundamentals (analysis, design and problem solving), but who also have the multi-disciplinary breadth that includes knowledge of human biology and clinical needs and applications, to be able to make an immediate impact in the field on graduation, in either the academic research or medical technology industry domains. Ultimately the programme aims to generate the future leaders of the national and international medical technology industry, and of academic research and teaching in biomedical engineering.

3. What’s special about CoEI/NUIG in this area:

• NUI Galway pioneered the development of educational programmes in Biomedical Engineering in Ireland, introducing the country’s first bachelor’s degree in Biomedical Engineering in 1998, that was the first to achieve professional accreditation from Engineers Ireland in 2004, and at the graduate level with the Structured PhD programme in Biomedical Engineering and Regenerative Medicine (BMERM) in 2011.
• NUI Galway has been at the forefront of world-class research in biomedical engineering for over 20 years and has pioneered multi-disciplinary research in biomedical engineering and science, with the establishment of the National Centre for Biomedical Engineering Science (NCBES) in 1999, and up to the present day with the announcement of NUI Galway as the lead institution in a new Science Foundation Ireland funded Centre for Research in Medical Devices (CÚRAM).
• NUI Galway has a very close and deep relationship with the medical device industry locally, nationally and internationally, at many levels, from industry visits, guest lectures and student placements, up to major research collaborations.
• Many of our engineering graduates now occupy senior management and technical positions in the medical device industry nationally and internationally.

4. Programme Structure – ECTS weights and split over semester; core/elective, etc.:

• 90ECTS programme
• one full year in duration, beginning September and finishing August
• comprises:
- Foundational taught modules (20 ECTS)
- Advanced taught modules (40 ECTS)
- Research/Industry Project (30 ECTS).

5. Programme Content – module names

Sample Modules:

Advanced Finite Element Methods
Advanced Computational Biomechanics
Advanced Biomaterials
Mechanobiology
Bioinstrumentation Design
Medical and Surgical Practice
Stem Cells and Gene Therapy
Translational Medicine
Polymer Engineering
Advanced Engineering Statistics
Systems Reliability
Lean Systems
Research Methods for Engineers
Financial Management
Regulatory Affairs and Case Studies
Technology, Innovation and Entrepreneurship

6. Any special funding arrangements – e.g. Irish Aid

Comment (PMcH): CoEI scholarships a great idea.

7. Opportunity for number of Industrial & Research internships.

Students enrolled on this programme will have an opportunity to apply for a one-year post-graduation internship in either a related industry or research group in Ireland.

8. Testimonials.

“The Biomedical Engineering programme at NUI Galway has given me the fundamental engineering skills and multi-disciplinary background in biology and clinical application that I needed to be able to make an immediate impact in industry and to be able to design and develop new medical implants and devices. My graduate education through my PhD in bone biomechanics was also very important in this because I directly combined engineering and biological analysis techniques to better understand how stem cells generate new bone, showing me how biomedical engineers can play a critically important role in generating new knowledge on how the body works, and how new treatments can be developed for diseases and injuries, such as osteoporosis.” Evelyn Birmingham, BE Biomedical Engineering (2009), PhD Biomedical Engineering (2014), R&D Engineer, Medtronic Vascular, Galway.

For further details

visit http://nuigalway.ie/engineering-informatics/internationalpostgraduatestudents/

How to Apply:

Applications are made online via the Postgraduate Applications Centre (PAC): https://www.pac.ie
Please use the following PAC application code for your programme:

M.Sc. Biomedical Engineering - PAC code GYE24

Scholarships :

Please visit our website for more information on scholarships: http://www.nuigalway.ie/engineering-informatics/internationalpostgraduatestudents/feesandscholarships/

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The advent of affordable rapid genome sequencing will produce enormous amounts of genetic data on both individuals and populations, and the challenge for scientists is to unlock the potential of this ‘big data’. Read more
The advent of affordable rapid genome sequencing will produce enormous amounts of genetic data on both individuals and populations, and the challenge for scientists is to unlock the potential of this ‘big data’. Doing so requires a new generation of scientists who can combine genetics and bioinformatics to understand how genomic changes cause diseases such as cancer, thus enabling the development of novel treatments, through drugs and gene therapy, and prevention strategies. With the huge expansion in number of individual genomes being sequenced, this is one of the fastest growing areas of biomedical science as we embrace the era of personalised medicine.

See the website http://www.brookes.ac.uk/Courses/Postgraduate/Medical-Genetics-and-Genomics/

Why choose this course?

- This is a 12 month full-time course, with part-time places available.

- Aimed at graduates (UK/ EU, International) wishing to develop skills and knowledge in human genetics and genome analysis for employment in the medical biotechnology/pharma and genomics sector, and those wishing to go on to do research degrees.

- This course will prepare you for entry into a career in medical genetics and genomics.

- Our lecturers conduct first-class research, with over 95% of Biological Science research internationally recognised in the 2014 REF.

- You will be taught by Oxford Brookes staff, with specialist lectures provided by staff of other partners in the Oxford Academic Health Sciences Centre, and will have a range of project opportunities using human genome data.

- The Faculty will invest over £8M in Bioscience facilities from 2015, with funding from HEFCE.

- Projects may be linked to specific needs and interests in the work-place, at Brookes or within other genomic laboratories under Brookes supervision. We also have strong links with local industry.

- We develop your transferable skills, particularly communication, organisation and research planning, which will assist you when carrying out your research project and can provide a basis for application for a research degree or career in genomics research.

Teaching and learning

The taught programme will be available with options for full-time and part-time MSc (180 credits), as well as individual CPD modules. Postgraduate Certificate and Diploma qualifications are also possible, requiring 60 and 120 credits, respectively.

Approach to assessment

Assessment methods used within the course are varied and are designed to be stimulating as well as academically rigorous. They are based on your learning needs, individual aims and the academic standards expected for the course.

You will receive unparalleled support from tutors and have access to state-of-the-art learning technologies via our Moodle platform. Our tutors have reputations for excellence and have established links with colleagues, organisations and institutions at national and international levels.

Embedded throughout the curriculum are skills that are essential to achieve quality outcomes for genomic medicine in practice. This will develop skills culminating in the research project, which will enable students to undertake research and evaluate new findings to implement in patient diagnosis, treatment and care, problem-based learning, work-based learning and inter-professional learning to develop skills for working in specialist and interdisciplinary teams. The development of skills in bioinformatics and use of genomic data will be a key outcome so the programme has a large proportion of hands on experience.

How this course helps you develop

You will develop the in-depth knowledge and specialised skills required to apply genetics and genomics theory to practical problems in the biomedical and pharmaceutical industries, and to undertake research in genetics and genome analysis.

Students will acquire knowledge and skills for employment or PhD positions in the expanding fields of genomics, bioinformatics, or other medically-related research, and academia.

During the course of this programme you will develop a network of colleagues and experts from this field.

Careers

- Research Degree/ PhD
- Pharmaceutical Industry
- Biomedical Industry
- NHS Scientist
- Medical Research
- Academia

Free language courses for students - the Open Module

Free language courses are available to full-time undergraduate and postgraduate students on many of our courses, and can be taken as a credit on some courses.

Please note that the free language courses are not available if you are:
- studying at a Brookes partner college
- studying on any of our teacher education courses or postgraduate education courses.

Research highlights

RESEARCH EXCELLENCE FRAMEWORK (REF) 2014
- Top post '92 University Biological Sciences submission

- 95% of research internationally recognised

- Double the percentage 4* and treble the percentage 3* research compared to 2008, with 58% of research being world leading or internationally excellent

- 80% of impact rated 3* or 4*

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