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The only Master’s specialisation in the Netherlands covering the function of our epigenome, a key factor in regulating gene expression and in a wide range of diseases. Read more

Master's specialisation in Medical Epigenomics

The only Master’s specialisation in the Netherlands covering the function of our epigenome, a key factor in regulating gene expression and in a wide range of diseases.
Our skin cells, liver cells and blood cells all contain the same genetic information. Yet these are different types of cells, each performing their own specific tasks. How is this possible? The explanation lies in the epigenome: a heritable, cell-type specific set of chromosomal modifications, which regulates gene expression. Radboud University is specialised in studying the epigenome and is the only university in the Netherlands to offer a Master’s programme in this field of research.

Health and disease

The epigenome consists of small and reversible chemical modifications of the DNA or histone proteins, such as methylation, acetylation and phosphorylation. It changes the spatial structure of DNA, resulting in gene activation or repression. These processes are crucial for our health and also play a role in many diseases, like autoimmune diseases, cancer and neurological disorders. As opposed to modifications of the genome sequence itself, epigenetic modifications are reversible. You can therefore imagine the great potential of drugs that target epigenetic enzymes, so-called epi-drugs.

Big data

In this specialisation, you’ll look at a cell as one big and complex system. You’ll study epigenetic mechanisms during development and disease from different angles. This includes studying DNA and RNA by next-generation sequencing (epigenomics) and analysing proteins by mass spectrometry (proteomics). In addition, you‘ll be trained to design computational strategies that allow the integration of these multifaceted, high-throughput data sets into one system.

Why study Medical Epigenomics at Radboud University?

- Radboud University combines various state-of-the-art technologies – such as quantitative mass spectrometry and next-generation DNA sequencing – with downstream bioinformatics analyses in one department. This is unique in Europe.
- This programme allows you to work with researchers from the Radboud Institute for Molecular Life sciences (RIMLS), one of the leading multidisciplinary research institutes within this field of study worldwide.
- We have close contacts with high-profile medically oriented groups on the Radboud campus and with international institutes (EMBL, Max-Planck, Marie Curie, Cambridge, US-based labs, etc). As a Master’s student, you can choose to perform an internship in one of these related departments.
- Radboud University coordinates BLUEPRINT, a 30 million Euro European project focusing on the epigenomics of leukaemia. Master’s students have the opportunity to participate in this project.

Career prospects

As a Master’s student of Medical Epigenomics you’re trained in using state-of-the art technology in combination with biological software tools to study complete networks in cells in an unbiased manner. For example, you’ll know how to study the effects of drugs in the human body.
When you enter the job market, you’ll have:
- A thorough background of epigenetic mechanisms in health and disease, which is highly relevant in strongly rising field of epi-drug development
- Extensive and partly hands-on experience in state-of-the-art ‘omics’ technologies: next-generation sequencing, quantitative mass spectrometry and single cell technologies;
- Extensive expertise in designing, executing and interpreting scientific experiments in data-driven research;
- The computational skills needed to analyse large ‘omics’ datasets.

With this background, you can become a researcher at a:
- University or research institute;
- Pharmaceutical company, such as Synthon or Johnson & Johnson;
- Food company, like Danone or Unilever;
- Start-up company making use of -omics technology.

Apart from research into genomics and epigenomics, you could also work on topics such as miniaturising workflows, improving experimental devices, the interface between biology and informatics, medicine from a systems approach.

Or you can become a:
- Biological or medical consultant;
- Biology teacher;
- Policy coordinator, regarding genetic or medical issues;
- Patent attorney;
- Clinical research associate;

PhD positions at Radboud University

Each year, the Molecular Biology department (Prof. Henk Stunnenberg, Prof. Michiel Vermeulen) and the Molecular Developmental Biology department (Prof. Gert-Jan Veenstra) at the RIMLS offer between five and ten PhD positions. Of course, many graduates also apply for a PhD position at related departments in the Netherlands, or abroad.

Our approach to this field

- Systems biology
In the Medical Epigenomics specialisation you won’t zoom in on only one particular gene, protein or signalling pathway. Instead, you’ll regard the cell as one complete system. This comprehensive view allows you to, for example, model the impact of one particular epigenetic mutation on various parts and functions of the cell, or study the effects of a drug in an unbiased manner. One of the challenges of this systems biology approach is the processing and integration of large amounts of data. That’s why you’ll also be trained in computational biology. Once graduated, this will be a great advantage: you’ll be able to bridge the gap between biology, technology and informatics , and thus have a profile that is desperately needed in modern, data-driven biology.

- Multiple OMICS approaches
Studying cells in a systems biology approach means connecting processes at the level of the genome (genomics), epigenome (epigenomics), transcriptome (transcriptomics), proteome (proteomics), etc. In the Medical Epigenomics specialisation, you’ll get acquainted with all these different fields of study.

- Patient and animal samples
Numerous genetic diseases are not caused by genetic mutations, but by epigenetic mutations that influence the structure and function of chromatin. Think of:
- Autoimmune diseases, like rheumatoid arthritis and lupus
- Cancer, in the forms of leukaemia, colon cancer, prostate cancer and cervical cancer
- Neurological disorders, like Rett Syndrome, Alzheimer, Parkinson, Multiple Sclerosis, schizophrenia and autism

We investigate these diseases on a cellular level, focusing on the epigenetic mutations and the impact on various pathways in the cell. You’ll get the chance to participate in that research, and work with embryonic stem cell, patient, Xenopus or zebra fish samples.

See the website http://www.ru.nl/masters/medicalbiology/epigenomics

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Fungal biology research will focus on yeasts, filamentous fungi and lichens. Projects will investigate the physiology, biochemistry, molecular genetics and genomics of these organisms, for example in the use of fungi as cell factories for the production of proteins and pharmaceuticals. Read more
Fungal biology research will focus on yeasts, filamentous fungi and lichens. Projects will investigate the physiology, biochemistry, molecular genetics and genomics of these organisms, for example in the use of fungi as cell factories for the production of proteins and pharmaceuticals. Other areas include stress response mechanisms and cell individuality in yeasts and filamentous fungi, the genetics of sexual reproduction in pathogenic fungi and those used in the biotechnology and food sectors, and the epigenetic control of gene transcription.

APPLICATION PROCEDURES

After identifying which Masters you wish to pursue please complete an on-line application form
https://pgapps.nottingham.ac.uk/
Mark clearly on this form your choice of course title, give a brief outline of your proposed research and follow the automated prompts to provide documentation. Once the School has your application and accompanying documents (eg referees reports, transcripts/certificates) your application will be matched to an appropriate academic supervisor and considered for an offer of admission.

COURSE STRUCTURE
The MRes degree course consists of two elements:
160 credits of assessed work. The assessed work will normally be based entirely on a research project and will be the equivalent of around 10 ½ months full-time research work. AND
20 credits of non-assessed generic training. Credits can be accumulated from any of the courses offered by the Graduate School. http://www.nottingham.ac.uk/gradschool/research-training/index.phtml The generic courses should be chosen by the student in consultation with the supervisor(s).

ASSESSMENT
The research project will normally be assessed by a dissertation of a maximum of 30,000 to 35,000 words, or equivalent as appropriate*. The examiners may if they so wish require the student to attend a viva.
*In consultation with the supervisor it maybe possible for students to elect to do a shorter research project and take a maximum of 40 credits of assessed modules.

The School of Life Sciences will provide each postgraduate research student with a laptop for their exclusive use for the duration of their studies in the School.

SCHOLARSHIPS FOR INTERNATIONAL STUDENTS
http://www.nottingham.ac.uk/studywithus/international-applicants/scholarships-fees-and-finance/scholarships/masters-scholarships.aspx

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The Cancer MSc reflects the depth and breadth of research interests, from basic science to translational medicine, within the UCL Cancer Institute. Read more
The Cancer MSc reflects the depth and breadth of research interests, from basic science to translational medicine, within the UCL Cancer Institute. The programme, taught by research scientists and academic clinicians, provides students with an in-depth look at the biology behind the disease processes which lead to cancer.

Degree information

This programme offers a foundation in understanding cancer as a disease process and its associated therapies. Students learn about the approaches taken to predict, detect, monitor and treat cancer, alongside the cutting-edge research methods and techniques used to advance our understanding of this disease and design better treatment strategies.

Students undertake modules to the value of 180 credits. The programme consists of two core modules (60 credits), four specialist modules (60 credits) and a research project (60 credits). A Postgraduate Diploma (120 credits, full-time nine months) is offered. A Postgraduate Certificate (60 credits, full-time 12 weeks) is offered.

Core modules
-Basic Biology and Cancer Genetics
-Cancer Therapeutics

Specialist modules
-Behavioural Science and Cancer
-Biomarkers in Cancer
-Cancer Clinical Trials
-Haematological Malignancies and Gene Therapy

Dissertation/report
All MSc students undertake a laboratory project, clinical trials project or systems biology/informatics project, which culminates in a 10,000–12,000 word dissertation and an oral research presentation.

Teaching and learning
Students develop their knowledge and understanding of cancer through lectures, self-study, database mining, wet-lab based practicals, clinical trial evaluations, laboratory training, assigned reading and self-learning. Each taught module is assessed by an unseen written examination and/or coursework. The research project is assessed by the dissertation (75%) and oral presentation (25%).

Careers

The knowledge and skills developed will be suitable for those in an industrial or healthcare setting, as well as those individuals contemplating a PhD or medical studies in cancer.

Top career destinations for this degree:
-Research Technician, NHS Imperial College Healthcare NHS Trust
-Cancer and Genetics, ETH Zurich
-PhD Cancer Research, University of New South Wales (UNSW)
-Clincial Trial Project Manager, Beijing Lawke Health Laboratory Inc.
-Research Scientist, SporeGen

Employability
Skills include critical evaluation of scientific literature, experimental planning and design interpretation of data and results, presentation/public speaking skills, time management, working with a team, working independently and writing for various audiences.

Why study this degree at UCL?

UCL is one of Europe's largest and most productive centres of biomedical science, with an international reputation for leading basic, translational and clinical cancer research.

The UCL Cancer Institute brings together scientists from various disciplines to synergise multidisciplinary research into cancer, whose particular areas of expertise include: the biology of leukaemia, the infectious causes of cancer, the design of drugs that interact with DNA, antibody-directed therapies, the molecular pathology of cancer, signalling pathways in cancer, epigenetic changes in cancer, gene therapy, cancer stem cell biology, early phase clinical trials, and national and international clinical trials in solid tumours and blood cancers.

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Investigate the effects of pathogens on the body, the intricacies of the human immune system and the impact of infections. You will also explore advanced medical microbiology, studying specific global health issues and the procedures involved in medical diagnostics. Read more
Investigate the effects of pathogens on the body, the intricacies of the human immune system and the impact of infections. You will also explore advanced medical microbiology, studying specific global health issues and the procedures involved in medical diagnostics.

Gain advanced laboratory skills and an in-depth knowledge of investigative methods being applied within the search for novel antimicrobial agents.

You will carry out extensive practical investigations, including quantifying the antimicrobial effects of compounds against specific microorganisms, or studying the mechanisms of microbial resistance to therapeutics. You'll have access to Class 2 microbiology facilities, along with cell culture, molecular virology and epigenetic research methods. With our new biomedical sciences research laboratory you will be able to conduct project work in a dedicated research environment and benefit from an enhanced range of equipment.

- Research Excellence Framework 2014: twice as many of our staff - 220 - were entered into the research assessment for 2014 compared to the number entered in 2008.

Visit the website http://courses.leedsbeckett.ac.uk/microbiology_biotechnology

Mature Applicants

Our University welcomes applications from mature applicants who demonstrate academic potential. We usually require some evidence of recent academic study, for example completion of an access course, however recent relevant work experience may also be considered. Please note that for some of our professional courses all applicants will need to meet the specified entry criteria and in these cases work experience cannot be considered in lieu.

If you wish to apply through this route you should refer to our University Recognition of Prior Learning policy that is available on our website (http://www.leedsbeckett.ac.uk/studenthub/recognition-of-prior-learning.htm).

Please note that all applicants to our University are required to meet our standard English language requirement of GCSE grade C or equivalent, variations to this will be listed on the individual course entry requirements.

Careers

You will be able to go into a range of careers, including those within pharmaceutical companies, food manufacturing, chemical facilities or developing further investigative and innovative research. A move into a more senior position will be available to you, such as senior researcher or laboratory analyst roles, where you would be involved in designing research projects and analysing the data generated.

- Medical Research Scientist
- Labratory Analyst
- Microbiologist

Careers advice: The dedicated Jobs and Careers team offers expert advice and a host of resources to help you choose and gain employment. Whether you're in your first or final year, you can speak to members of staff from our Careers Office who can offer you advice from writing a CV to searching for jobs.

Visit the careers site https://www.leedsbeckett.ac.uk/employability/jobs-careers-support.htm

Course Benefits

You will spend a considerable proportion of your time in a hands-on environment, spending over 200 hours within the biomedical science laboratories, completing practicals and working on a specific research project that interests you and aligns with our expertise.

We will give you access to Class 2 microbiology facilities, along with cell culture and micro-electric fabrication equipment. With our new dedicated biomedical sciences research laboratory (opened in 2013) you will be able to conduct project work in a dedicated research environment and will benefit from an enhanced range of equipment.

You'll benefit from working with a first class teaching team. One of our lecturers, Dr Margarita Gomez Escalada, developed internationally-recognised research data on treating acne using the ingredient thyme, with a student who performed all the practical tests for her project.

Core Modules

Contemporary Research In Biomedical Science
Discuss and evaluate current research in biomedical sciences and relate this both to the theoretical basis of the subject and to the methodologies used to generate the data.

Advanced Professional Practice and Research
Gain a grounding in the different approaches to research, including quantitatative and qualitative data collection methods. You will then be able to plan research, effectively search for and evaluate research literature and be able to apply and analyse data using appropriate statistical tests.

Bio-analytical Techniques
Combine theory and practice of many modern analytical techniques that are used in biological, medical and chemical analysis, and learn the important steps in the development and assessment of analytical measures.

Infection and Immunity
Develop an in-depth understanding of the infection process, taking into consideration the pathogenesis process both from the point of view of the pathogen as well as the host where the immune response will be investigated.

Advanced Medical Microbiology
Look at different aspects of current trends in microbiological research, and use laboratory sessions to undertake problem solving activities such as the planning of a class lab activity and mini projects.

Applied Biotechnology
Study up to date issues concerning current biotechnological products and processes, especially with regard to the use of microorganisms and recombinant DNA techniques.

Research Project
Undertake an independent research project within the remit of expertise of our course team. Design experimental methods to test your aims or hypotheses and report the findings in the form of both a thesis and an oral presentation.

Dr. Margarita Gomez Escalada

Senior Lecturer

"I find it really exciting to generate new data and ideas alongside my students and collaborators, which may one day lead to changes in the ways in which we tackle diseases caused by microorganisms. Teaching allows me to share and explore these latest findings with those who will go on to work in the field."

Margarita recently produced internationally-recognised research treating acne with herbal compounds. Working with a student, she discovered that an extract of thyme was more effective than traditional chemical-based creams.

Facilities

- Biomedical Research Laboratory
The latest scientific testing equipment lets you put your learning into practice and break new ground in biomedical research.

- Library
Our libraries are two of the only university libraries in the UK open 24/7 every day of the year. However you like to study, the libraries have got you covered with group study, silent study, extensive e-learning resources and PC suites.

- Biomedical Sciences Laboratory
Housing state-of-the-art IT and AV facilities, our new Biomedical Sciences laboratory provides important, cutting edge facilities for our students including walk-in cold rooms.

Find out how to apply here - http://www.leedsbeckett.ac.uk/postgraduate/how-to-apply/

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This vocational training programme has been developed to appeal to recent biology, biomedical, biochemistry and medical graduates who aspire to develop a career in the field of clinical embryology and assisted reproductive technology (ART) and/or the associated reproductive sciences. Read more

Introduction and Course Objectives

This vocational training programme has been developed to appeal to recent biology, biomedical, biochemistry and medical graduates who aspire to develop a career in the field of clinical embryology and assisted reproductive technology (ART) and/or the associated reproductive sciences. The programme has been developed by the Division of Reproduction and Early Development within the Leeds Institute of Genetics, Health and Therapeutics in association with the clinicians and embryologists working at the Leeds Centre of Reproductive Medicine in the Leeds NHS Trust. The programme leaders have over 20 years of experience of training clinical embryologists, reproductive medicine practitioners and reproductive scientists.

This is a laboratory-based science degree not a clinically- based infertility treatment course. The programme will provide students with a detailed knowledge of the theory and practices that underpin human clinical embryology and ART. The curriculum covers: the cell and molecular biology of human reproduction, fertility, andrology and embryology; the management and efficient running of an ART laboratory; the practices, genetic and epigenetic concepts of micromanipulation and techniques such as intracytoplasmic sperm injection (ICSI) and pre-implantation genetic diagnosis (PGD); advances in cryobiology and its application to gamete and embryo freezing and fertility preservation. It will also provide graduates with valuable insights into the theory underpinning clinical treatments and the ethical and legal controversies surrounding assisted reproduction in humans. The programme will equip graduates to pursue a career in human assisted reproduction (e.g. clinical embryology, infertility treatment) and/or research in the reproductive sciences.

The programme places a strong emphasis on all aspects of practical training for clinical embryology and assisted reproduction technology. Masters students will be tutored in research methods. They will receive hands-on training from specialist practitioners in andrology, gamete handling, IVF, ICSI, embryo culture, gamete and embryo freezing, vitrification, biopsy. Students will interact with established, clinical embryologists and reproductive medicine specialists.

Course Content:

The course will comprise the following compulsory modules:

• Fundamentals of Clinical Embryology;
• IVF and Embryo Culture;
• Micromanipulation;
• Cryobiology and Cryopreservation;
• Ethics and Law for Embryologists;
• Research in Reproduction, Embryology and Assisted Reproduction Technology

Course Delivery

This programme is delivered using a blended learning approach which combines lectures, seminars, tutorials, interactive group discussions, presentations and problem based learning sessions /case studies with self directed learning. The theoretical training is complimented by the conduct of original research and by laboratory-based practical sessions. The course content is further enhanced by an extensive array of online resources and by the provision of printed versions of all module workbooks. Course assessments will include essays, presentations, projects, practical log books, a research dissertation and examinations.

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RESEARCH STRENGTHS AND FACILITIES. The Department of Medical Genetics Graduate Program is a leading program that attracts students from all over Canada and the world. Read more

Graduate Program

RESEARCH STRENGTHS AND FACILITIES
The Department of Medical Genetics Graduate Program is a leading program that attracts students from all over Canada and the world. The Program offers Master’s and Doctoral programs that take place in Vancouver, one of the world’s most livable cities, at locations affiliated with the University of British Columbia, an institution which is consistently ranked among the world’s best universities.

The Department is composed of dozens of faculty members at the forefront of their fields who use cutting edge genetic, epigenetic, genomic, and bioinformatic methodologies to gain insight into diseases such as cancer, diabetes, obesity, neurodegenerative and neurological disorders, and other genetic diseases. Research is highly interactive and often involves local, national, and international collaborations which further enrich the research experience.

Individual labs conduct clinical and/or translational research and basic experimental research engaging a wide variety of approaches including the use of model organisms such as mice, flies (D. melanogaster), worms (C. elegans), and yeast (S. cerevisiae). Prospective students with interests in the investigative areas below have an opportunity to pursue world class research in labs affiliated with the Medical Genetics Graduate Program.

Areas of Research

- Developmental genetics and birth defects
- Epigenetics and chromosome transmission
- Genomics and bioinformatics
- Genetic epidemiology and human gene mapping
- Neurogenetics and immunogenetics
- Stem cells and gene therapy
- Pharmacogenomics
- Clinical genetics, genetic counselling, ethics and policy

Quick Facts

- Degree: Master of Science
- Specialization: Medical Genetics
- Subject: Life Sciences
- Mode of delivery: On campus
- Program components: Coursework + Thesis required
- Faculty: Faculty of Medicine

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Modern genetics has today evolved beyond its traditional boundaries to become a fundamental part of biology and medicine. Read more
Modern genetics has today evolved beyond its traditional boundaries to become a fundamental part of biology and medicine. The Department reflects this pervasiveness, with research interests encompassing several high impact themes, including functional genomics and systems biology, developmental genetics, epigenetic Inheritance, evolution and population genetics, microbial genetics, and cell biology. The Department of Genetics hosts between 50 and 65 postgraduate students across 25 research groups, researching a wide range of biological problems, from population genetics and ecology, to the detailed analysis of genome sequence. The Department is based in a historic building on the Downing Site but has research groups located in the Gurdon Institute, Cambridge Systems Biology Centre and Sainsbury Labs as well as an impressive range of local, national and international collaborations.

MPhil students in the Department will undertake a 1-year project under the supervision of one of our Group Leaders, where they will develop an original research question and address this through laboratory or computer based research. They will receive training in appropriate research methods and in literature research skills to prepare them for writing an MPhil thesis within the year.

See the website http://www.graduate.study.cam.ac.uk/courses/directory/blgempmbs

Course detail

By the end of the programme, students will have:

- a comprehensive understanding of techniques, and a thorough knowledge of the literature, applicable to their own research;
- demonstrated originality in the application of knowledge, together with a practical
- understanding of how research and enquiry are used to create and interpret knowledge in their field;
- shown abilities in the critical evaluation of current research and research techniques and methodologies;
- demonstrated some self-direction and originality in tackling and solving problems, and acted autonomously in the planning and implementation of research.

Format

- Supervision meetings once every one or two weeks.

- Weekly Departmental seminars.

- Annual Research In Genetics day with poster sessions

Assessment

Thesis required of not more than 20,000 words in length, excluding figures, tables, footnotes, appendices and bibliography. The examination will include an oral examination on the thesis and on the general field of knowledge within which it falls.

Continuing

Candidates wishing to progress to the PhD degree after successful completion of an MPhil will be considered by the Departmental Graduate Education Committee on a case by case basis. Candidates will be expected to have identified a suitable research group to host the PhD research and identify an appropriate source of funding.

How to apply: http://www.graduate.study.cam.ac.uk/applying

Funding Opportunities

There are no specific funding opportunities advertised for this course. For information on more general funding opportunities, please follow the link below.

General Funding Opportunities http://www.graduate.study.cam.ac.uk/finance/funding

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The Pre-Masters in Biomedical Science (Graduate Diploma in Biomedical Science) provides a discipline-specific pathway (a pre-masters year) into the taught Biomedical Blood Science masters level programme. Read more

Overview

The Pre-Masters in Biomedical Science (Graduate Diploma in Biomedical Science) provides a discipline-specific pathway (a pre-masters year) into the taught Biomedical Blood Science masters level programme. It is a one-year full-time programme designed for both home and international students, with a background in life sciences, who wish to study at postgraduate level for the MSc in Biomedical Blood Science. The programme is open to science graduates who do not meet the academic criteria for a direct entry into the MSc. The MSc in Biomedical Blood Science is accredited by the Institute of Biomedical Science (IBMS). The IBMS is the professional body of Biomedical Scientists within the United Kingdom. The IBMS aims to promote and develop the role of Biomedical Science within healthcare to deliver the best possible service for patient care and safety.

See the website https://www.keele.ac.uk/pgtcourses/biomedicalsciencegraduatediploma/

Course Aims

The overall aim is to provide the students with the academic background necessary for the masters programme and to enable them to develop and practise the subject specific academic skills required for the intensive pace of study at masters level. The course also aims to allow international students to benefit from English language support that will help them to develop their academic English language skills.

Intended learning outcomes of the programme reflect what successful students should know, understand or to be able to do by the end of the programme. Programme specific learning outcomes are provided in the Programme Specification available by request; but, to summarise, the overarching course aims are as follows:

- To provide students with core knowledge, understanding and skills relevant to Biomedical Science

- To produce skilled and motivated graduates who are suitably prepared for the MSc in Biomedical Science and for further study.

- To cultivate interest in the biosciences, particularly at the cellular and molecular level, within a caring and intellectually stimulating environment.

- To get an accurate insight into the role of Biomedical Scientists in the diagnosis, treatment and monitoring of disease.

- To develop an understanding of the analytical, clinical and diagnostic aspects of Cellular Pathology, Clinical Biochemistry, Medical Microbiology, Blood Transfusion, Clinical Immunology and Haematology pathology laboratories.

- To promote the development of a range of key skills, for use in all areas where numeracy and an objective, scientific approach to problem-solving are valued.

- To provide students with a wide range of learning activities and a diverse assessment strategy in order to fully develop their employability and academic skills, ensuring both professional and academic attainment.

- To promote the development of critical thinking, autonomous learning, independent research and communication skills to help prepare the students for the MSc in Biomedical Blood Science and for a lifetime of continued professional development.

Course Content

All the modules in this one year programme are compulsory. The programme consists of a total of 90 credits made up of one 30 credit module and four 15 credit modules. An additional English module (English for Academic Purposes) will be offered for non-native English speakers if required. This module will not form part of the overall award, but successful completion is required for progression to the Masters programme.

Modules:
- Biomedical Science and Pathology (30 credits):
The module provides the student with the knowledge and understanding of the pathobiology of human disease associated with Cellular Pathology, Clinical Immunology, Haematology, Clinical Biochemistry, Medical Microbiology and Clinical Virology. It also examines the analytical and clinical functions of three more of the major departments of a modern hospital pathology laboratory, including Haematology, Clinical Pathology, Clinical Immunology, Blood Transfusion, Clinical Biochemistry and Medical Microbiology. In addition, the module will give an accurate insight into the role of Biomedical Scientists and how they assist clinicians in the diagnosis, treatment and monitoring of disease.

- Biochemistry Research Project (non-experimental) (15 credits):
This module aims to introduce students to some of the key non-experimental research skills that are routinely used by biochemists and biomedical scientists, such as in depth literature searching, analysis of experimental data and the use of a computer as tool for both research (bioinformatics) and dissemination of information (web page construction). The student will research the literature on a specific topic, using library and web based resources and will produce a written review. In addition, the student will either process and interpret some raw experimental data provided to them.

- Advances in Medicine (15 credits):
This module will describe and promote the understanding of advances in medicine that have impacted on diagnosis, treatment, prevention of a range of diseases. It will highlight fast emerging areas of research which are striving to improve diagnosis including nanotechnology and new biochemical tests in the fields of heart disease, cancer and fertility investigations which will potentially improve patient care.

- Clinical Pathology (15 credits):
The majority of staff that contribute to the module are employees of the University Hospital of North Staffordshire (UHNS). Students will benefit from lectures and expertise in Clinical Diagnostic Pathology, Pharmacology, Biochemistry, Genetics and Inflammatory Diseases. Students will gain an insight into how patients are managed, from their very first presentation at the UHNS, from the perspective of diagnosis and treatment. The course will cover both standardised testing options and the development of new diagnostic procedures with a particular emphasis on genetic and epigenetic aspects of disease. Students will also gain an appreciation of the cost benefit of particular routes for diagnosis and treatment and the importance of identifying false positive and false negative results. Finally, the students will have the opportunity to perform their own extensive literature review of a disease-related topic that is not covered by the lectures on the course.

- Case Studies in Biomedical Science (15 credits):
This module aims to give you an understanding of the UK health trends and the factors that affect these trends. Through clinical case studies and small group tutorials, you will explore why the UK has some of the highest incidences of certain diseases and conditions in Europe and consider what factors contribute to making them some of the most common and/or rising health problems faced by this country. This will include understanding the relevant socioeconomic factors as well as understanding the bioscience of the disease process and its diagnosis and management. You will also focus on what is being done by Government and the NHS to tackle these major health problems.

- English for Academic Purposes (EAP ):
For non-native English speakers if required

Teaching & Assessment

In addition to the lecture courses and tutorials, problem based learning (PBL) using clinical scenarios is used for at least one module. Students will also be given the opportunity to undertake an independent non-experimental research project, supervised and supported by a member of staff. Web-based learning using the University’s virtual learning environment (KLE) is also used to give students easy access to a wide range of resources and research tools, and as a platform for online discussions and quizzes. Students will be given many opportunities to become familiar with word processing, spreadsheets and graphics software as well as computer-based routes to access scientific literature.

All modules are assessed within the semester in which they are taught. Most contain elements of both ‘in-course’ assessment (in the form of laboratory reports, essays, posters) and formal examination, although some are examined by ‘in-course’ assessment alone.

Additional Costs

Apart from additional costs for text books, inter-library loans and potential overdue library fines we do not anticipate any additional costs for this post graduate programme.

Find information on Scholarships here - http://www.keele.ac.uk/studentfunding/bursariesscholarships/

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The University of Edinburgh Centre for Genomics and Experimental Medicine (CGEM) is part of the MRC / University of Edinburgh Institute of Genetics and Molecular Medicine (IGMM). Read more

Research profile

The University of Edinburgh Centre for Genomics and Experimental Medicine (CGEM) is part of the MRC / University of Edinburgh Institute of Genetics and Molecular Medicine (IGMM). CGEM’s mission is to use genetics and genomics to understand the mechanisms of disease and design novel intervention strategies. Our research has consistently obtained the highest possible ranking in national assessments of research excellence.

We undertake detailed studies of populations, families and individuals to study a wide range of health related conditions. We use state-of-the-art genetic, epigenetic, genomic, statistical, bioinformatic, biological and molecular approaches in model systems and clinical studies for systematic investigation of disease aetiology. With this knowledge, we aim to improve disease prediction, prevention and prognosis. Our translational agenda encompasses the development of new medicines and genetically-informed use of existing medicines in clinical trials.

Training and support

CGEM offers an exceptional, well-managed and well-equipped laboratory environment for cutting edge research and research training. Within CGEM there are ~25, and within the IGMM over a hundred, PhD students, overseen by a well-established Graduate School structure.

Training sessions for PhD students are available in a wide variety of topics. These include: good research practice; experimental design; data analysis and statistics; student-supervisor working relationships; research ethics and assessment mechanisms, as well as lectures/workshops on specific wet and dry laboratory techniques.

There is a Postgraduate Studies Committee (PGSC) which is responsible for student training and assessment. Its role is to develop and implement guidelines for optimal student training, and to ensure best practice in monitoring and assessment. Assessments are carried out by carefully selected thesis committees, who remain with the student throughout their PhD. The committees consist of the Supervisors, an External Member (with expertise relevant to the student’s project) and an experienced Chair. The students also have a thriving postgrad society which runs career talks, social events and an annual scientific retreat.

Facilities

A principal aim of both CGEM and the IGMM is develop fully integrated, multi-disciplinary research programmes across the whole spectrum of basic, clinical and translational research. We have state of the art imaging, DNA sequencing and drug discovery units, a bioinformatics service and excellent lab facilities.

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