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Masters Degrees (Drug Delivery)

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Why this course?. The global drug delivery sector is set to attain significant growth over the next five years. This is driven by the introduction of technologies with improved product features. Read more

Why this course?

The global drug delivery sector is set to attain significant growth over the next five years. This is driven by the introduction of technologies with improved product features. As the pharmaceutical industry continues to innovate in order to maintain growth and profitability, the use of new drug delivery technologies is being explored for many treatment areas.

The introduction of new routes of delivery combined with increasing research and development spend, has created a new market for drug delivery and there is a market need for employees with matched skill sets.

What you'll study

The programme provides specialist research training and practical experience in the design and development of effective drug delivery systems, as well as promoting directly applicable skills for career and professional development.

This course is designed to provide a robust postgraduate training and skills development for life science or physical science-based graduate students seeking employment in the pharmaceutical industry or at the life sciences interface.

The course aims to:

  • develop your understanding of the biology of specific targets for drug-based intervention
  • develop your understanding of the biopharmaceutical, pharmacokinetic & physicochemical principles important in the design and formulation of drug dosage systems
  • address the latest advances in drug delivery & targeting & develop your understanding of the concept of drug targeting using drug carriers & provide an in depth appreciation of the strategies available & utilised for a particular drug & biological barrier
  • enhance your research skills & transferable skills relevant to drug delivery in preparation for a career in the pharmaceutical industry or academia including leadership skills & entrepreneurship
  • develop your understanding of advanced research methodology to enable you to carry out independent work of publishable standard

Major projects

Within your project, you'll have the exciting opportunity to work alongside leading researchers developing the next generation of drug delivery systems. We offer a range of topics from nano to macro drug delivery systems and we consider a wide range of delivery strategies.

Facilities

The Strathclyde Institute of Pharmacy & Biomedical Sciences offers an excellent environment for research and teaching. It’s located in a new building with several laboratories. All are fitted with the latest equipment.

The course will also provide students with full experiential learning with facilities including:

  • formulation & manufacturing facilities
  • thermo-analytical facilities
  • particle, microparticle & nanoparticle size & surface analysis
  • dissolution analysis facilities
  • freeze-drying
  • in-vitro analysis

The course is also supported by access to the full range of analytical spectroscopic and chromatographic instrumentation for the characterisation of drug and drug delivery components, including:

  • nuclear Magnetic Resonance (NMR)
  • ultra-violet (UV)
  • attenuated total reflectance fourier transform infrared spectroscopy (ATR_FTIR)
  • mass spectrometry (MS)
  • high-pressure liquid chromatography (HPLC)
  • gas chromatography (GC)
  • liquid chromatograph/gas chromatography mass spectrometry (LC/GC-MS)

Learning & teaching

The course is delivered through lectures, tutorials and hands-on practical sessions.

If you successfully complete the required taught classes you may undertake a laboratory project for the MSc.

Assessment

Assessment of taught classes is through multiple choice tests, computer quizzes, problem solving scenarios, poster and oral presentations, essays, and formal written exams. The laboratory project is assessed through a written thesis.

Careers

This Masters programme is designed to support your career journey into the field of drug delivery and pharmaceutical sciences and provide the support for you to take up an exciting role within the pharmaceutical industry or continue your research career into a PhD programme.



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This course is one of our three specialist pharmacy MSc courses (Pharmaceutical Sciences, Drug Delivery, or Pharmacokinetics). Read more
This course is one of our three specialist pharmacy MSc courses (Pharmaceutical Sciences, Drug Delivery, or Pharmacokinetics).

You’ll gain a thorough understanding and awareness of your chosen area of pharmacy, the research methods required to complete a final supervised research project and an overview of the drug discovery process.

These courses are primarily designed to prepare you for an academic or industrial career in the relevant area. You may be a scientist already working within the pharmaceutical industry or a recent science graduate.

You will undertake a variety of compulsory modules and a research project. This project will last approximately four months and you will work under the supervision of recognised experts in their field. The project allows you to undertake a detailed investigation and develop practical expertise in a specialist pharmaceutical sciences area. The University also has strong links with numerous pharmaceutical companies - there may be the opportunity to undertake your project in collaboration with one of these companies.

You will gain an overview of the drug development process from concept to market, gaining hands-on experience of pharmaceutical formulation and drug delivery.

What you will study

All students studying one of our three pharmacy MSc courses will take the following core modules:
-Research Methods 1: Professional Development
-Research Methods 2: Communication Skills
-Research Project
-Drug Discovery

Depending upon the course you chose, you will also undertake the following modules:
-Chemotherapy & Selective Toxicity
-Drug Dosage Form & Design
-Principles of Product Analysis and Validation
-Drug Delivery and Targeting

Learning, teaching & assessment

Ranked in the UK's top 10 in the 2017 Complete University Guide, Aston Pharmacy excellent links with the profession. In addition, our research profile ensures relevant, expertise-led teaching for the students who enrol onto our courses each year. We have a long history of proving sector-leading courses - did you know that Aston Pharmacy School can trace its roots back to 1841?

You will learn in lectures, seminars, workshops and tutorials. Some modules may also use computer modelling and simulation sessions.

Our courses are assessed by a mixture of coursework, examinations, practical work and oral and written presentations. The research project module will be assessed on the basis of a submitted project report and an oral defence of a poster.

Your future career prospects

Graduates from our MSc programmes have taken up careers within the Pharmaceutical Industry in various disciplines such as analytical sciences, formulation development and project management. Our programmes provide the wider context and practical laboratory experience for pursuing careers in regulatory affairs, scientific writing and further studies.

Recent graduates have entered roles such as:
-Assistant Lecturer, University of Sulaimaniyah
-Associate Product Manager, AstraZeneca
-Business Development Manager, Crete Designs Limited
-Clinical Technician / Worker, Bridgewater Hospital
-Compound Technician, Sterling Pharmaceuticals
-Drug Designer, Unspecified Drug Company
-Drug Safety Specialist, PPD
-Drug Store Manager, Qaiwan group company
-Inhalation R & D Analyst, Aesica Pharmaceuticals Ltd (R5)
-Lecturer, University of Lagos, Nigeria
-Locum Pharmacist, various
-Molecular Modeller / Community Pharmacist, Verax Care Pharmacy
-OSD Technologist, GSK
-Pharma Benefit Associate, UnitedHealth Group
-Pharmacist, Government of India
-Pharmacist, Kerbala University
-Pharmacologist, Unspecified
-PhD Research Scholar, NIRMA University
-Recruitment Consultant, SRG
-Regulatory affairs trainee, PharmaLeaf India Pvt Ltd
-Research assistant, University of Leeds
-Research Scientist, Pluss Polymers
-Research Scientist, Wintean
-Researcher, Sunny Pharmtech Inc.
-Sales Relationship Coordinator, Wesley Assurance Society
-Science Teacher, Perry Beeches School
-Senior Regulatory officer, Roche Pharmaceuticals

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More about this course. The Pharmaceutical Science and Drug Delivery Systems MSc has been designed to develop your understanding of how drug delivery systems are constructed for specific deployment and controlled release of therapeutic agents. Read more

More about this course

The Pharmaceutical Science and Drug Delivery Systems MSc has been designed to develop your understanding of how drug delivery systems are constructed for specific deployment and controlled release of therapeutic agents. If you're a science graduate with a desire to work in this field, then this course will help you develop the knowledge and skills you'll need.

A flexible modular course, this master's course is designed to promote your personal and professional development. You can choose to start in the autumn or spring and follow either a part-time or full-time study route, allowing you to fit study around your personal and working life. Learning support will be delivered through lectures, tutorials, seminars and practical workshops.

All modules are taught by experts in their field and are supported by our online web-based learning environment accessible from outside the University at any time of day or night.

You'll study five core taught modules and then have a choice of one optional module, from the list of taught MSc modules offered by the subject group, over two semesters. You’ll then carry out an independent research project under the guidance of an experienced academic supervisor during the summer term.

If you’re already be working for a pharmaceutical company and have ambitions to acquire greater knowledge of the field, then this course will greatly contribute to your career advancement and continuing professional development (CPD).

Assessment

You'll be assessed through self-diagnostic testing, debates, group work, coursework, essays, and cumulative exams. Practical skills are assessed through the coursework assignments, including those in the research project module. Data handling skills are assessed by practical reports, problem solving exercises, information abstracting and reviewing exercises, poster presentations, exams and seminar presentations.



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- https://www.kent.ac.uk/locations/medway/. This programme builds on a very successful in-house training programme implemented by a major pharmaceutical company. Read more

This course will be held at the Medway Campus

- https://www.kent.ac.uk/locations/medway/

This programme builds on a very successful in-house training programme implemented by a major pharmaceutical company.

It was designed and conceived by pharmaceutical industry experts in drug discovery and will be delivered and assessed by experts in this field at the School of Pharmacy.

The MSc covers how fundamental science is applied to the discovery and development of medicines and the main aims are to:

- provide you with the experience of critically appraising the research questions and techniques that are routine in the pharmaceutical industry workplace

- produce graduates trained in the processes by which fundamental science is linked to the design and development of modern medicines

- provide expert preparation for students who wish to pursue a career in drug discovery, or wish to proceed to a PhD.

Visit the website https://www.kent.ac.uk/courses/postgraduate/736/applied-drug-discovery

Duration: One year full-time (campus based), two years part-time (distance learning)

About Medway School of Pharmacy

Medway School of Pharmacy is one of the few regional schools of pharmacy in the UK, a collaboration between the University of Kent and the University of Greenwich.

The impetus for the formation of the Medway School of Pharmacy came from the local community, who recognised the shortage of qualified pharmacists in all branches of the pharmacy profession in Kent.

The School is now recognised as an established school with accreditation from the General Pharmaceutical Council (GPhC) and the Health and Care Professions Council (HCPC). Graduates are employed in health disciplines in Kent and the south-east and more broadly across the UK.

Course structure

This programme is taught as either a classic one year full-time programme with attendance required on Mondays and Tuesdays for 48 weeks plus an additional study day off-campus, or delivered through distance e-learning using an interactive virtual learning environment on a two-year part-time basis.

The programme comprises 60 credits at certificate level, 60 credits at diploma level and 60 credits at Master’s level. You may choose to end your study at any one of these stages.

Modules

The following modules are indicative of those offered on this programme. This list is based on the current curriculum and may change year to year in response to new curriculum developments and innovation. Most programmes will require you to study a combination of compulsory and optional modules. You may also have the option to take modules from other programmes so that you may customise your programme and explore other subject areas that interest you.

Assessment

Assessment is by 100% coursework; including scientific reports, assignments, essays, a research project and portfolio entries.

Programme aims

This programme aims to:

- produce graduates trained in the processes by which fundamental science is linked to the design and development of modern medicines

- teach you an understanding of the drug discovery process

- provide you with expanded training in the biological sciences technical skills that underpin the processes of drug discovery

- provide you with the experience of critically appraising the research questions and techniques they use routinely in the workplace

- develop a variety of postgraduate level intellectual and transferable skills

- equip you with lifelong learning skills necessary to keep abreast of developments in drug discovery

- provide you with opportunities for shared multidisciplinary learning in drug discovery

- give you the experience of undertaking an independent research project

- provide expert preparation for students who wish to pursue and/or further a career in drug discovery, or wish to proceed to a higher degree (PhD) in topics related to the drug discovery process

- provide access to as wide a range of students as practicable irrespective of race, background, gender or physical disability from both within the UK and from overseas.

Research areas

- Chemistry and drug delivery

This group has laboratories with dedicated state-ofthe art drug delivery, nanotechnology, spectroscopy, chromatography and organic synthesis facilities. It brings together researchers in medicinal chemistry and drug design, nanotechnology and materials science, drug delivery and pharmaceutics encouraging a multidisciplinary approach to research. Research covers synthesis and biological evaluation of potential anti-cancer agents, structurebased drug design, QSAR predication of ADMET properties, controlled release, particle engineering, powder technology, pharmaceutical technology, and novel drug delivery systems, with a focus on respiratory drug delivery.

- Biological sciences

This group is housed in recently refurbished laboratories with dedicated state-of-the-art molecular biological, electrophysiological, tissue culture and microscopy facilities. The research is divided into four main themes; infectious diseases and allergy; neuroscience; renal and cardiovascular physiology; and pharmacology. Examples of current work include: investigation of the use of non-pathogenic virus ‘pseudotypes’ to study pathogenic RNA, study of the properties of neuronal potassium channels and their modulation and the development of new therapies for patients that have developed acute kidney injury in collaboration with a major pharmaceutical company.

- Pharmacy practice

This group conducts research in two areas: public health and medicines optimisation, with a particular focus on cardiovascular diseases and mental health. Work in public health includes studies in physical exercise, alcohol, cardiovascular screening and spirometry testing, plus pharmacovigilance. Studies in medicines optimisation include work in dementia, bipolar disorder and stroke, with an emphasis on the patient perspective.

Careers

Graduates who obtain their PhD from Kent or Greenwich are highly sought after by prospective employers, both within the UK and overseas. Destinations for doctoral graduates include university academic departments, research institutes and leading pharmaceutical and biotechnological companies.

The taught postgraduate programmes are designed to promote the continuing professional development by providing sought-after skills. The programmes are beneficial for those who wish to develop their skills and/or to take the next step in their career. While the MSc in Applied Drug Discovery produces elite drug discovery personnel, who can pursue a career in the pharmaceutical industry or academia.

Find out how to apply here - https://www.kent.ac.uk/courses/postgraduate/apply/

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- https://www.kent.ac.uk/locations/medway/. The Medway School of Pharmacy’s innovative postgraduate distance-learning programme in Medicines Management equips healthcare professionals with the skills and knowledge to contribute effectively to medicines management services and to individual drug therapy decisions. Read more

This course will be held at the Medway Campus

- https://www.kent.ac.uk/locations/medway/

The Medway School of Pharmacy’s innovative postgraduate distance-learning programme in Medicines Management equips healthcare professionals with the skills and knowledge to contribute effectively to medicines management services and to individual drug therapy decisions.

The programme emphasises clinical and costeffective prescribing in the context of holistic consideration of patient needs, and one of its pathways offers you the chance to qualify as an independent/supplementary prescriber.

Visit the website https://www.kent.ac.uk/courses/postgraduate/738/medicines-management

About Medway School of Pharmacy

Medway School of Pharmacy is one of the few regional schools of pharmacy in the UK, a collaboration between the University of Kent and the University of Greenwich.

The impetus for the formation of the Medway School of Pharmacy came from the local community, who recognised the shortage of qualified pharmacists in all branches of the pharmacy profession in Kent.

The School is now recognised as an established school with accreditation from the General Pharmaceutical Council (GPhC) and the Health and Care Professions Council (HCPC). Graduates are employed in health disciplines in Kent and the south-east and more broadly across the UK.

Course structure

You can register for the full MSc programme or undertake stand-alone modules. Modules can be put together to form a short course programme. Module length varies from five to 15 credits.

For the PCert, you must complete 60 credits, of which at least 20 must be from core modules. Diploma students must complete 120 credits, of which at least 40 credits must be from core modules. To gain the MSc, you must complete a 60-credit research project, write a dissertation and present the results as a poster.

Modules

The following modules are indicative of those offered on this programme. This list is based on the current curriculum and may change year to year in response to new curriculum developments and innovation. Most programmes will require you to study a combination of compulsory and optional modules. You may also have the option to take modules from other programmes so that you may customise your programme and explore other subject areas that interest you.

Assessment

Assessment includes case study analysis, critical appraisal of literature, assignments including short essays, a research project and dissertation.

Programme aims

This programme aims to:

- equip healthcare professionals with the skills and knowledge to contribute effectively to medicines management services and to individual drug therapy decisions in primary and secondary care.

- enable you to incorporate your learning directly into your workplace and to rise to the challenges presented by the new, patient-centred NHS.

Research areas

- Chemistry and drug delivery

This group has laboratories with dedicated state-ofthe art drug delivery, nanotechnology, spectroscopy, chromatography and organic synthesis facilities. It brings together researchers in medicinal chemistry and drug design, nanotechnology and materials science, drug delivery and pharmaceutics encouraging a multidisciplinary approach to research. Research covers synthesis and biological evaluation of potential anti-cancer agents, structurebased drug design, QSAR predication of ADMET properties, controlled release, particle engineering, powder technology, pharmaceutical technology, and novel drug delivery systems, with a focus on respiratory drug delivery.

- Biological sciences

This group is housed in recently refurbished laboratories with dedicated state-of-the-art molecular biological, electrophysiological, tissue culture and microscopy facilities. The research is divided into four main themes; infectious diseases and allergy; neuroscience; renal and cardiovascular physiology; and pharmacology. Examples of current work include: investigation of the use of non-pathogenic virus ‘pseudotypes’ to study pathogenic RNA, study of the properties of neuronal potassium channels and their modulation and the development of new therapies for patients that have developed acute kidney injury in collaboration with a major pharmaceutical company.

- Pharmacy practice

This group conducts research in two areas: public health and medicines optimisation, with a particular focus on cardiovascular diseases and mental health. Work in public health includes studies in physical exercise, alcohol, cardiovascular screening and spirometry testing, plus pharmacovigilance. Studies in medicines optimisation include work in dementia, bipolar disorder and stroke, with an emphasis on the patient perspective.

Careers

Graduates who obtain their PhD from Kent or Greenwich are highly sought after by prospective employers, both within the UK and overseas. Destinations for doctoral graduates include university academic departments, research institutes and leading pharmaceutical and biotechnological companies.

The taught postgraduate programmes are designed to promote the continuing professional development by providing sought-after skills. The programmes are beneficial for those who wish to develop their skills and/or to take the next step in their career.

Find out how to apply here - https://www.kent.ac.uk/courses/postgraduate/apply/

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- https://www.kent.ac.uk/locations/medway/. This programme provides general-level hospital pharmacists – registered with the GPhC and working – with the core skills required to provide holistic pharmaceutical care in the practice setting. Read more

This course will be held at the Medway Campus

- https://www.kent.ac.uk/locations/medway/

This programme provides general-level hospital pharmacists – registered with the GPhC and working – with the core skills required to provide holistic pharmaceutical care in the practice setting.

The programme aligns with a nationally agreed pharmacy practitioner development strategy and is the result of a unique collaboration of higher education institutions across London and the south and east of England.

The programme develops your knowledge and skills in clinical pharmacy practice and medicines management. It works on a philosophy of student-centred workplace learning, supported by workbooks and contact days facilitated by experienced pharmacy practitioners. You are expected to take responsibility for managing your learning and achieving the programme objectives. The ethos and culture of the programme is to enhance and develop self-reliance and an adult approach to learning in support of continuing professional development.

Visit the website https://www.kent.ac.uk/courses/postgraduate/737/general-pharmacy-practice

About Medway School of Pharmacy

Medway School of Pharmacy is one of the few regional schools of pharmacy in the UK, a collaboration between the University of Kent and the University of Greenwich.

The impetus for the formation of the Medway School of Pharmacy came from the local community, who recognised the shortage of qualified pharmacists in all branches of the pharmacy profession in Kent.

The School is now recognised as an established school with accreditation from the General Pharmaceutical Council (GPhC) and the Health and Care Professions Council (HCPC). Graduates are employed in health disciplines in Kent and the south-east and more broadly across the UK.

Modules

For more about the structure of this course please visit the Medway School of Pharmacy website (http://www.msp.ac.uk/studying/postgraduate/cert-gen-pharm-pract/index.html).

Assessment

Assessment is by Objective Structure Clinical Examination (OSCE), multiple-choice questions, assignments, literature review, prescribing audit, change management project, and a competency-based portfolio review.

Programme aims

The PCert and PDip aim to:

- enable you to apply appropriate knowledge, skills and attitudes in order to carry out effectively the role of the general pharmacist practitioner within your pharmacy practice base and wider healthcare teams

- enable you to carry out effective consultations with patients respecting their diverse needs and with regard to confidentiality and consent

- enable you to identify, prioritise and resolve complex pharmaceutical care issues

- enable you to apply knowledge of pathophysiology, pharmacology and the clinical use of drugs and therapeutic guidelines to the treatment of common disease states

- enable you to access, gather, interpret, critically evaluate and summarise medicines information

- enable you to monitor the quality of services provided, identify, prioritise and resolve significant medicines management issues and monitor and evaluate outcomes

- enable you to establish population health needs and apply specialist pharmaceutical knowledge to public health issues.

The MSc aims are to:

- investigate a topic in depth

- evaluate current practice or a new service

- publish research and advance knowledge in pharmacy practice

- develop skills you require for the RPS Advanced Pharmacy Framework

- inspire you and others in your workplace to carry out much needed practice research

- support your future career and perhaps to help you explore new career paths.

Research areas

Chemistry and drug delivery
This group has laboratories with dedicated state-ofthe art drug delivery, nanotechnology, spectroscopy, chromatography and organic synthesis facilities. It brings together researchers in medicinal chemistry and drug design, nanotechnology and materials science, drug delivery and pharmaceutics encouraging a multidisciplinary approach to research. Research covers synthesis and biological evaluation of potential anti-cancer agents, structurebased drug design, QSAR predication of ADMET properties, controlled release, particle engineering, powder technology, pharmaceutical technology, and novel drug delivery systems, with a focus on respiratory drug delivery.

Biological sciences
This group is housed in recently refurbished laboratories with dedicated state-of-the-art molecular biological, electrophysiological, tissue culture and microscopy facilities. The research is divided into four main themes; infectious diseases and allergy; neuroscience; renal and cardiovascular physiology; and pharmacology. Examples of current work include: investigation of the use of non-pathogenic virus ‘pseudotypes’ to study pathogenic RNA, study of the properties of neuronal potassium channels and their modulation and the development of new therapies for patients that have developed acute kidney injury in collaboration with a major pharmaceutical company.

Pharmacy practice
This group conducts research in two areas: public health and medicines optimisation, with a particular focus on cardiovascular diseases and mental health. Work in public health includes studies in physical exercise, alcohol, cardiovascular screening and spirometry testing, plus pharmacovigilance. Studies in medicines optimisation include work in dementia, bipolar disorder and stroke, with an emphasis on the patient perspective.

Careers

This programme provides progression for pharmacists towards advanced practitioner status.

Completion of the practice elements of the course leads to the award of the Certificate of Completion of General Pharmacist Training from an accredited training centre.

Find out how to apply here - https://www.kent.ac.uk/courses/postgraduate/apply/

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- https://www.kent.ac.uk/locations/medway/. This programme, approved by the appropriate professional/regulatory bodies, provides a distance learning option for qualification as a non-medical prescriber. Read more

This course will be held at the Medway Campus

- https://www.kent.ac.uk/locations/medway/

This programme, approved by the appropriate professional/regulatory bodies, provides a distance learning option for qualification as a non-medical prescriber.

Eight contact days cover communication and diagnostic skills. Other topics on the syllabus include the legal, policy, professional and ethical aspects of prescribing, plus pharmacology and patient assessment and monitoring.

Visit the website https://www.kent.ac.uk/courses/postgraduate/740/independent-supplementary-prescribing

About Medway School of Pharmacy

Medway School of Pharmacy is one of the few regional schools of pharmacy in the UK, a collaboration between the University of Kent and the University of Greenwich.

The impetus for the formation of the Medway School of Pharmacy came from the local community, who recognised the shortage of qualified pharmacists in all branches of the pharmacy profession in Kent.

The School is now recognised as an established school with accreditation from the General Pharmaceutical Council (GPhC) and the Health and Care Professions Council (HCPC). Graduates are employed in health disciplines in Kent and the south-east and more broadly across the UK.

Course structure

You can take the Master’s programme as a stand-alone PCert in Independent/Supplementary Prescribing, or as one pathway into the Medicines Management programme, by studying prescribing as either the first or second year of the Medicines Management PDip.

On successful completion, the School will notify the appropriate professional/regulatory body that you have qualified as an independent/supplementary prescriber.

Modules

The following modules are indicative of those offered on this programme. This list is based on the current curriculum and may change year to year in response to new curriculum developments and innovation. Most programmes will require you to study a combination of compulsory and optional modules. You may also have the option to take modules from other programmes so that you may customise your programme and explore other subject areas that interest you.

Assessment

Assessment is by Objective Structured Clinical Examination (OSCE), assignments, case-study analysis, multiple-choice questions, short answer paper, narrative based on portfolio entries and attendance at a period of learning in practice.

Programme aims

This programme aims to:

- prepare pharmacists to practice as supplementary prescribers

- prepare nurses and midwives to practice as supplementary/independent prescribers

- develop the knowledge and skills required by an allied health professional to practice as a supplementary prescriber

- meet the standards set by the respective professional or regulatory body as required within the legislative framework.

Research areas

Chemistry and drug delivery
This group has laboratories with dedicated state-ofthe art drug delivery, nanotechnology, spectroscopy, chromatography and organic synthesis facilities. It brings together researchers in medicinal chemistry and drug design, nanotechnology and materials science, drug delivery and pharmaceutics encouraging a multidisciplinary approach to research. Research covers synthesis and biological evaluation of potential anti-cancer agents, structurebased drug design, QSAR predication of ADMET properties, controlled release, particle engineering, powder technology, pharmaceutical technology, and novel drug delivery systems, with a focus on respiratory drug delivery.

Biological sciences
This group is housed in recently refurbished laboratories with dedicated state-of-the-art molecular biological, electrophysiological, tissue culture and microscopy facilities. The research is divided into four main themes; infectious diseases and allergy; neuroscience; renal and cardiovascular physiology; and pharmacology. Examples of current work include: investigation of the use of non-pathogenic virus ‘pseudotypes’ to study pathogenic RNA, study of the properties of neuronal potassium channels and their modulation and the development of new therapies for patients that have developed acute kidney injury in collaboration with a major pharmaceutical company.

Pharmacy practice
This group conducts research in two areas: public health and medicines optimisation, with a particular focus on cardiovascular diseases and mental health. Work in public health includes studies in physical exercise, alcohol, cardiovascular screening and spirometry testing, plus pharmacovigilance. Studies in medicines optimisation include work in dementia, bipolar disorder and stroke, with an emphasis on the patient perspective.

Careers

Graduates who obtain their PhD from Kent or Greenwich are highly sought after by prospective employers, both within the UK and overseas. Destinations for doctoral graduates include university academic departments, research institutes and leading pharmaceutical and biotechnological companies.

The taught postgraduate programmes are designed to promote the continuing professional development by providing sought-after skills. The programmes are beneficial for those who wish to develop their skills and/or to take the next step in their career.

Find out how to apply here - https://www.kent.ac.uk/courses/postgraduate/apply/

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- https://www.kent.ac.uk/locations/medway/. Start. At any time but preferably in September. Our research programme in Pharmacy gives you the integrated, broad-based research training needed to exploit current advances in pharmaceutical and biological sciences and pharmacy practice. Read more

This course will be held at the Medway Campus

- https://www.kent.ac.uk/locations/medway/

Start: At any time but preferably in September

Our research programme in Pharmacy gives you the integrated, broad-based research training needed to exploit current advances in pharmaceutical and biological sciences and pharmacy practice.

Within the school we have a number of home, EU and international postgraduate students who are undertaking doctoral research degrees. Graduates who obtain their PhD from Kent or Greenwich are highly sought after by prospective employers, both within the UK and overseas. Destinations for doctoral graduates include university academic departments, research institutes and leading pharmaceutical and biotechnological companies.

Visit the website https://www.kent.ac.uk/courses/postgraduate/171/pharmacy

About Medway School of Pharmacy

Medway School of Pharmacy is one of the few regional schools of pharmacy in the UK, a collaboration between the University of Kent and the University of Greenwich.

The impetus for the formation of the Medway School of Pharmacy came from the local community, who recognised the shortage of qualified pharmacists in all branches of the pharmacy profession in Kent.

The School is now recognised as an established school with accreditation from the General Pharmaceutical Council (GPhC) and the Health and Care Professions Council (HCPC). Graduates are employed in health disciplines in Kent and the south-east and more broadly across the UK.

Study support

- Postgraduate resources

Postgraduate students have access to all the facilities at the Medway School of Pharmacy, including clinical skills labs and a ‘simulation man’. As the School of Pharmacy is a joint venture between the two universities, students have access to facilities at Kent’s Medway and Canterbury campuses, and the University of Greenwich.

- Dynamic publishing culture

Medway School of Pharmacy has a research culture and as such postgraduate students publish regularly and widely in journals, conference proceedings and books. Among others, they have recently contributed to: International Journal of Pharmacy Practice; Nephron Physiology; Acta Physiologica; Purinergic Signalling; and European Journal of Pharmacology.

- Researcher Development Programme

Kent's Graduate School co-ordinates the Researcher Development Programme for research students, which includes workshops focused on research, specialist and transferable skills. The programme is mapped to the national Researcher Development Framework and covers a diverse range of topics, including subjectspecific research skills, research management, personal effectiveness, communication skills, networking and teamworking, and career management skills

Research areas

The Medway School of Pharmacy houses strong and vibrant research groups that span a range of pharmacy-related areas. Staff have a wealth of research experience, and UK and international links with both industry and academic institutions.

- Chemistry and drug delivery

This group has laboratories with dedicated state-ofthe art drug delivery, nanotechnology, spectroscopy, chromatography and organic synthesis facilities. It brings together researchers in medicinal chemistry and drug design, nanotechnology and materials science, drug delivery and pharmaceutics encouraging a multidisciplinary approach to research. Research covers synthesis and biological evaluation of potential anti-cancer agents, structurebased drug design, QSAR predication of ADMET properties, controlled release, particle engineering, powder technology, pharmaceutical technology, and novel drug delivery systems, with a focus on respiratory drug delivery.

- Biological sciences

This group is housed in recently refurbished laboratories with dedicated state-of-the-art molecular biological, electrophysiological, tissue culture and microscopy facilities. The research is divided into four main themes; infectious diseases and allergy; neuroscience; renal and cardiovascular physiology; and pharmacology. Examples of current work include: investigation of the use of non-pathogenic virus ‘pseudotypes’ to study pathogenic RNA, study of the properties of neuronal potassium channels and their modulation and the development of new therapies for patients that have developed acute kidney injury in collaboration with a major pharmaceutical company.

- Pharmacy practice

This group conducts research in two areas: public health and medicines optimisation, with a particular focus on cardiovascular diseases and mental health. Work in public health includes studies in physical exercise, alcohol, cardiovascular screening and spirometry testing, plus pharmacovigilance. Studies in medicines optimisation include work in dementia, bipolar disorder and stroke, with an emphasis on the patient perspective.

Careers

Graduates who obtain their PhD from Kent or Greenwich are highly sought after by prospective employers, both within the UK and overseas. Destinations for doctoral graduates include university academic departments, research institutes and leading pharmaceutical and biotechnological companies.

Find out how to apply here - https://www.kent.ac.uk/courses/postgraduate/apply/

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Medway School of Pharmacy is a joint venture between the Universities of Greenwich and Kent. Since 2004, the Department has invested heavily in facilities and equipment. Read more
Medway School of Pharmacy is a joint venture between the Universities of Greenwich and Kent. Since 2004, the Department has invested heavily in facilities and equipment: it houses strong and vibrant research groups that span a range of pharmacy-related areas. Staff have a wealth of research experience and UK and international links with both industry and academic institutions. Our excellent relationship with both Greenwich and Kent gives the Department access to world-class research facilities. PhD studentships are awarded on a competitive basis and in a broad range of research areas, including chemistry and drug delivery, biological sciences and pharmacy practice.

The programme aims to give postgraduate students the integrated, broad-based research training needed to exploit the advances in pharmaceutical and biological sciences and pharmacy practice for conducting contemporary research. We also offer part-time MPhil/PhD programmes.

Visit the website http://www2.gre.ac.uk/study/courses/pg/res/pharm

What you'll study

Research areas and recent research topics include:

Chemistry and drug delivery
Synthesis and biological evaluation of potential anti-cancer agents
Structure-based drug design
Quantitive structure-activity relationship (QSAR) predication of ADMET properties
Controlled release
Particle engineering
Powder technology
Pharmaceutical technology
Novel drug delivery systems with a focus on respiratory drug delivery
Pharmacology, cell and molecular biology
Cancer gene therapy
Immunology of allergic response
Neuropharmacology
Neurobiology (circadian rhythms)
Control of microbial infection
Ion channels and their role in disease states
Pharmacy practice
Rational cost-effective use of drugs
Pharmaceutical care - with an emphasis on new models of care for specific patient groups
Medicines management
Pharmaceutical services, ethics and pharmacy practice

Fees and finance

Your time at university should be enjoyable and rewarding, and it is important that it is not spoilt by unnecessary financial worries. We recommend that you spend time planning your finances, both before coming to university and while you are here. We can offer advice on living costs and budgeting, as well as on awards, allowances and loans.Find out more about our fees and the support available to you at our:

- Postgraduate finance pages (http://www.gre.ac.uk/finance/pg)
- International students' finance pages (http://www.gre.ac.uk/finance/international)

Assessment

Students are assessed through their thesis and an oral examination.

Career options

Graduates from this programme can pursue positions in the pharmaceutical industry, consultancy, the NHS and other parts of the public sector, and academia.

Find out how to apply here - http://www2.gre.ac.uk/study/apply

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OVERVIEW. The. Oncology Drug Discovery MSc. course is designed to provide an insight into how existing and future drug targets are identified from biological samples isolated from the cancer clinic. Read more

OVERVIEW

The Oncology Drug Discovery MSc course is designed to provide an insight into how existing and future drug targets are identified from biological samples isolated from the cancer clinic. This will include an industrial viewpoint into what makes an interesting target and how, through an iterative process, this target is validated. In addition, lectures will be provided to discuss how ‘hit’ compounds are identified, in both the academic and industrial setting, using compound screen assays and fragment based screening technologies. We will also provide an insight in computational methods for generating chemical ‘hits’. The module will also cover how these ‘hit’ compounds are prosecuted into tool compounds or Lead Optimisation candidates (LO), both historic and modern, that are used to further validate a potential drug target.

During this second module we will provide an insight into the challenges of moving a compound from an LO candidate to a pre-clinical candidate. How bio-marker companion tests are developed, validated and are used to underpin clinical trials. The lectures will also provide a keen insight into novel formulation strategies currently under development within Queen’s University Belfast. In addition, we will also provide an insight into the development of bio-therapeutics, such as antibodies, that are proving to be a powerful alternative to small molecule based therapeutics.

For further information email  or send us a message on WhatsApp

ONCOLOGY DRUG DISCOVERY HIGHLIGHTS

The strong links between us and the biotech and bio-pharmaceutical sectors provides a stimulating translational environment, while also expanding your career opportunities.

GLOBAL OPPORTUNITIES

INDUSTRY LINKS

  • Research projects will be provided by both academic staff and local biotech companies in ground-breaking research areas with a strong focus on clinical applications.

WORLD CLASS FACILITIES

  • The Oncology Drug Discovery course will be taught and mentored within the Centre for Cancer Research and Cell Biology: a purpose-built institute at the heart of the Health Sciences Campus, boasting state-of-the-art research facilities.

INTERNATIONALLY RENOWNED EXPERTS

  • We have an international reputation in this area, achieved through: high-impact peer review publications significant international research funding, the establishment of successful spin-out companies.

 

COURSE STRUCTURE

Research Project

  • You will undertake a lab based project in a number of different facets of the drug development, such as hit identification, hit compound development and therapeutic antibody development pathway working with both academic and biotech groups.Semester 1

Research Translational: from Concept to Commercialisation (Full Year)

  • This module covers the principles of disease biology and new technological developments that increase our understanding of disease processes. It develops an appreciation of the importance of innovation, business awareness and leadership skills in the translation of discovery science to clinical implementation.

Diagnosis and Treatment of Cancer

  • This module provides a comprehensive overview of the diagnosis and treatment of the common solid and haematological malignancies, including breast, ovarian, genitourinary and gastrointestinal cancers as well as the leukaemias

Cancer Biology

  • This module provides a comprehensive overview of the fundamental principles of carcinogenesis, highlighting how normal control processes are bypassed during tumour formation. The pathogenic mechanisms to be discussed will range from genomic alterations in key gene families, to epigenetic mechanisms of gene control, alterations in kinase activities or protein turnover, or activation of aberrant phenotypes such as invasion and angiogenesis.Semester 2

Target Identification and Development in Drug Discovery

  • This module describe how novel drug targets are identified and validated and identifies how biochemical assays are developed and employed in the drug discovery process. It also evaluates the alternative approaches used in the drug discovery to identify new chemical matter. It describes and defines chemical approaches used in developing ‘hit’ chemical compounds and identifies drug target classes and their drug-like pharmacophores.

Drug optimization, drug delivery and clinical trials

  • This module evaluates the issues associated the drug development process and describes the development, validation and use of bio-markers in the drug discovery process. It discusses the practices employed in clinical trials and defines the processes employed in licensing of new chemical equity and the role it plays in the drug discovery process.

For further information email  or send us a message on WhatsApp



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This exciting new MSc is designed to equip students with an in-depth knowledge of all aspects of drug discovery, integrating teaching in chemistry and biology to develop graduates who have exceptional scientific understanding and a host of transferable skills. Read more

Overview

This exciting new MSc is designed to equip students with an in-depth knowledge of all aspects of drug discovery, integrating teaching in chemistry and biology to develop graduates who have exceptional scientific understanding and a host of transferable skills. The course blends the two fundamental disciplines underpinning drug delivery, and provides students with the opportunity to practise background theory within the productive research-led environments offered by the Schools of Pharmacy and Biomedical Sciences. Nottingham has world-leading expertise in the areas of drug discovery and pharmaceutical science, and students on this course will have the chance to learn directly from staff at the forefront of the field.

The course content covers all aspects of drug delivery, and includes a 12-week (60 credit) research project based in our laboratories, encouraging the practical application of the theory taught within the programme.

The course will be technology-rich, using online learning packages to supplement face-to-face teaching and innovative assessment methods.

Aims

The overall aim of the MSc is to develop knowledge and understanding, cognitive skills, key skills and practical and professional skills in the area of Drug Discovery and Pharmaceutical Science. The overall drug discovery process from ‘concept to clinic’ provides the reference point for the education and training delivered in the more specific scientific and regulatory aspects.

Students will, therefore, be able to develop an understanding of the scientific principles underlying the main topic areas housed within the arena of drug discovery. In addition, upon completing the degree students will be able to make effective use of electronic communication and information search & retrieval to facilitate development of key critical skills with which to assess and analyse a broad array of scientific literature.

Further information



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As a researcher in the School of Pharmacy, you have the opportunity to liaise with leaders in the pharmaceutical and biotechnology industries and to develop strong national and international collaborations. Read more
As a researcher in the School of Pharmacy, you have the opportunity to liaise with leaders in the pharmaceutical and biotechnology industries and to develop strong national and international collaborations.

Research in the School is diverse and multidisciplinary and is generally grouped around two distinct strands: 1) pharmacy education and community engagement with prescribing, and 2) physical pharmaceutics and drug development and delivery. Subsequently, there are opportunities for research students to work with academics across varied topics, including solid-state drug development and biologics delivery.

As a postgraduate student, you can benefit from specialist laboratory space and equipment, a wide range of training programmes designed to enhance your research and transferable skills, as well as support from dedicated academic supervisors.

All of our research students are encouraged to submit papers to scientific journals, present their findings at conferences in the UK and overseas, and share knowledge with colleagues across the University.

Research Areas, Projects & Topics

The School’s research is diverse and multidisciplinary and it includes the following areas:
-Solid state drug development
-Crystal engineering of salts/polymorphs/co-crystals
-Biologics delivery
-Nanomedicine and targeted drug delivery
-Mucosal delivery of biologics
-Mucosal models to study drug delivery
-Antimicrobials and vaccines
-Organic chemistry
-Bioconjugations and Bio-inspired chemistry
-Development of sequence selective DNA cross-linking agents
-Health education
-Personalised care
-Data-based medicine and assessment of individual risks/benefits
-Application and use of evidence, and pharmacy-led clinical medication reviews

How You Study

Our research environment aims to support students through a specific framework. This covers all aspects of the postgraduate experience, including supervisor interaction, training and access to the facilities and allied support through the Directors of Research and Postgraduates Studies, from initial application to final completion.

All postgraduates are actively encouraged to prepare submission to scientific journals in their field. Students are expected to present their findings to national and international conferences, and also to participate in internal research meetings.

Due to the nature of postgraduate research programmes, the vast majority of your time will be spent in independent study and research. You will have meetings with your academic supervisor(s), with the regularity of these varying depending on your own individual requirements, subject area and the stage of your programme.

How You Are Assessed

A PhD is usually awarded based on the quality of your thesis and your ability in an oral examination (viva voce) to present and successfully defend your chosen research topic to a group of academics. You are also expected to demonstrate how your research findings have contributed to knowledge or developed existing theory or understanding.

Facilities

Our Science and Innovation Park, home to the Joseph Banks Laboratories, provides specialist teaching suites and laboratories for study and research. It is a regional hub for science industry innovation and development.

Career and Personal Development

Graduates may progress to careers in the pharmaceutical, cosmetics or food industries, while others may choose to work within academia.

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As a researcher in the School of Pharmacy, you have the opportunity to liaise with leaders in the pharmaceutical and biotechnology industries and to develop strong national and international collaborations. Read more
As a researcher in the School of Pharmacy, you have the opportunity to liaise with leaders in the pharmaceutical and biotechnology industries and to develop strong national and international collaborations.

Research in the School is diverse and multidisciplinary and is generally grouped around two distinct strands: 1) pharmacy education and community engagement with prescribing, and 2) physical pharmaceutics and drug development and delivery. Subsequently, there are opportunities for research students to work with academics across varied topics, including solid-state drug development and biologics delivery.

As a postgraduate student, you can benefit from specialist laboratory space and equipment, a wide range of training programmes designed to enhance your research and transferable skills, as well as support from dedicated academic supervisors.

All of our research students are encouraged to submit papers to scientific journals, present their findings at conferences in the UK and overseas, and share knowledge with colleagues across the University.

Research Areas, Projects & Topics

The School’s research is diverse and multidisciplinary and it includes the following areas:
-Solid state drug development
-Crystal engineering of salts/polymorphs/co-crystals
-Biologics delivery
-Nanomedicine and targeted drug delivery
-Mucosal delivery of biologics
-Mucosal models to study drug delivery
-Antimicrobials and vaccines
-Organic chemistry
-Bioconjugations and Bio-inspired chemistry
-Development of sequence selective DNA cross-linking agents
-Health education
-Personalised care
-Data-based medicine and assessment of individual risks/benefits
-Application and use of evidence, and pharmacy-led clinical medication reviews

How You Study

Our research environment aims to support students through a specific framework. This covers all aspects of the postgraduate experience, including supervisor interaction, training and access to the facilities and allied support through the Directors of Research and Postgraduates Studies, from initial application to final completion.

All postgraduates are actively encouraged to prepare submission to scientific journals in their field. Students are expected to present their findings to national and international conferences, and also to participate in internal research meetings.

Due to the nature of postgraduate research programmes, the vast majority of your time will be spent in independent study and research. You will have meetings with your academic supervisor(s), with the regularity of these varying depending on your own individual requirements, subject area and the stage of your programme.

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This programme provides a broad overview of the drug discovery and development process and is designed for graduates in science-based subjects as preparation for either PhD-level research or a career in the pharmaceutical industry or with a government regulatory body. Read more

This programme provides a broad overview of the drug discovery and development process and is designed for graduates in science-based subjects as preparation for either PhD-level research or a career in the pharmaceutical industry or with a government regulatory body.

About this degree

You will gain hands-on experience of molecular modelling and computer-based drug design, and analytical and synthetic techniques and be exposed to modern platforms for drug discovery and methods of drug synthesis.

Students undertake modules to the value of 180 credits.

The programme consists of three core modules (90 credits), two optional modules (30 credits) and a dissertation (60 credits).

Core modules

  • Modern Aspects of Drug Discovery
  • The Process of Drug Discovery and Development I
  • The Process of Drug Discovery and Development II

Optional modules

Students choose two from the following:

  • Anticancer Personalised Medicines
  • New Drug Targets in the CNS
  • Pharmacogenics, Adverse Drug Reactions and Biomarkers
  • Advanced Structure-based Drug Design

Dissertation/report

All students undertake a laboratory-based research project which is assessed at the end of the year by a written report and oral presentation.

Teaching and learning

The programme is delivered through a combination of lectures, tutorials and seminars supported by the Blackboard e-learning system and practical classes. Assessment is through a combination of written examination and coursework. The research project is assessed by written report and oral presentation.

Further information on modules and degree structure is available on the department website: Drug Discovery and Development MSc

Careers

Students who complete the Drug Delivery and Development MSc will progress to careers in the various aspects of the pharmaceutical and biotechnology industries including research, product development and manufacturing, clinical trials and regulatory affairs.

Recent career destinations for this degree

  • PhD Medicinal Chemistry, UCL

Careers data is taken from the ‘Destinations of Leavers from Higher Education’ survey undertaken by HESA looking at the destinations of UK and EU students in the 2013–2015 graduating cohorts six months after graduation.

Why study this degree at UCL?

Lectures and seminars from industry-based scientists and visits to industrial and biotechnological research laboratories are key features of this programme.

Our graduates include international students from 24 different countries

The programme covers marketing, licensing and the regulatory affairs that form an integral part of the development process

Research Excellence Framework (REF)

The Research Excellence Framework, or REF, is the system for assessing the quality of research in UK higher education institutions. The 2014 REF was carried out by the UK's higher education funding bodies, and the results used to allocate research funding from 2015/16.

The following REF score was awarded to the department: School of Pharmacy

87% rated 4* (‘world-leading’) or 3* (‘internationally excellent’)

Learn more about the scope of UCL's research, and browse case studies, on our Research Impact website.



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We have scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy. Read more

We have scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy. This spans the fundamental understanding and concepts of drug action, the discovery of new drugs and development of medicines, the clinical management and rationale use of medicines, through to the professional role of the pharmacist in improving public health.

As a postgraduate research student studying for an MPhil or PhD, you will be based within the School of Pharmacy and a research institute in the Faculty of Medical Sciences relevant to your proposed research. Our research institutes are as follows:

If your research involves clinical components there may be a partnership with the NHS.

The School of Pharmacy's focus is on multidisciplinary translational research, work that is relevant to real life. We combine world-class laboratory and clinical research facilities with an open environment where scholars, clinicians and researchers benefit from working side-by-side. You will spend your time within research teams led by experts in their field, in a friendly and supportive atmosphere.

We offer MPhil and PhD supervision in the following research areas:

Disease-Selective Medicines

The discovery and development of new small molecule therapeutics with improved disease selectivity and reduced systemic toxicities, through the use of rational drug design and synthesis, lead optimisation, and preclinical evaluation in cellular disease model systems. We are particularly interested in the development of cancer prodrugs with tumour specific activation and reduced systemic toxicity, and novel therapies for improved treatment of infective diseases including Dengue and other haemorrhagic fever viruses and Tuberculosis, amongst others.

Improved Strategies for the Treatment of Chronic Pain

Understanding the molecular mechanisms that generate and maintain the symptoms and processes of chronic pain, and its translation to effective strategies for pain control, including opioid treatment.

Cellular Physiology

Understanding the pathways that allow hormones to control epithelial ion channel activity and physiological action, particularly the control of sodium channel activity in the distal nephron and consequent hypo/hyper-tension.

Safety Pharmacology and Discovery Toxicology

Development and utilisation of new preclinical tools for identification of therapeutics with potential safety liabilities, particularly novel clinically relevant cell models and systems for detection of effects upon the heart.

Pharmaceutics and Chemical Principles of Dosage Form Design

Pharmaceutical formulations to deliver active molecules to treat disease. We have active research on intermolecular interactions, nanoscale pharmaceutics and nanotherapeutics, including dosage form design from intermolecular interactions, and delivery of biopharmaceuticals. In particular research is focused on:

  • determining strategies for improving drug solubility and altering materials properties to enable effective drug delivery and the production of enhanced medicines.
  • supramolecular Pharmaceutics, particularly inter/intramolecular interactions and kinetics leading to, during and after self-assembly of small organic molecules.
  • fundamental and translational nanomedicines
  • understanding and improving drug delivery via the subcutaneous, inhaled and intravitreal routes of delivery

Pharmaceutical Public Health

The role of community pharmacy as a central fulcrum to address health inequalities and behaviour change in relation to smoking, alcohol and substance misuse, sexual health and obesogenic behaviours, amongst others. As the community pharmacy is the most frequent point of contact for patients and public within the wider primary healthcare team, we evaluate the dynamics and interactions of this relationship and the potential role for pharmacy within the early diagnosis of disease and improvements in public health.

Rational Medicines Use

The safe and efficient use of medicines in primary and secondary care is central to the role of every pharmacist. However, medicines are becoming increasingly complex and patients are being given more preventative medicine focused at improving their health, which poses clear risks and significant potential for complications. Rationalisation of medicine usage crosses care boundaries, applies both within primary and secondary care, and furthermore at the care interface. We investigate prescribing habits and the mechanisms to support patients who may take complex medicines for a significant portion of their life

Patient Safety and Health Information Technology

Medication errors can result in patient injury or death, and are preventable. These errors can occur at the stages of ordering, transcription, dispensing and administration. We conduct studies around key technological advances targeted towards intercepting these errors and improving patient safety. Our research focuses on evaluation of specific health information technology prevention strategies throughout the medication use process, with a particular emphasis on health information technology, including its broader implications for medical care and policy. We also explore the different types and causes of errors that occur during the prescribing process when using electronic systems, providing national and international recommendations for their improvement.



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