We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments.
As a student you will be registered with a University research institute, for many this is the Institute for Cellular Medicine (ICM). You will be supported in your studies through a structured programme of supervision and training via our Faculty of Medical Sciences Graduate School.
We undertake the following areas of research and offer MPhil, PhD and MD supervision in:
Newcastle hosts one of the most comprehensive organ transplant programmes in the world. This clinical expertise has developed in parallel with the applied immunobiology and transplantation research group. We are investigating aspects of the immunology of autoimmune diseases and cancer therapy, in addition to transplant rejection. We have themes to understand the interplay of the inflammatory and anti-inflammatory responses by a variety of pathways, and how these can be manipulated for therapeutic purposes. Further research theme focusses on primary immunodeficiency diseases.
There is strong emphasis on the integration of clinical investigation with basic science. Our research include:
We also research the effects of UVR on the skin including mitochondrial DNA damage as a UV biomarker.
This area emphasises on translational research, linking clinical- and laboratory-based science. Key research include:
Focus is on applied research and aims to underpin future clinical applications. Technology-oriented and demand-driven research is conducted which relates directly to health priority areas such as:
This research is sustained through extensive internal and external collaborations with leading UK and European academic and industrial groups, and has the ultimate goal of deploying next-generation diagnostic and therapeutic systems in the hospital and health-care environment.
There is a number of research programmes into the genetics, immunology and physiology of kidney disease and kidney transplantation. We maintain close links between basic scientists and clinicians with many translational programmes of work, from the laboratory to first-in-man and phase III clinical trials. Specific areas:
We have particular interests in:
Novel non-invasive methodologies using magnetic resonance are developed and applied to clinical research. Our research falls into two categories:
Our studies cover a broad range of topics (including diabetes, dementia, neuroscience, hepatology, cardiovascular, neuromuscular disease, metabolism, and respiratory research projects), but have a common theme of MR technical development and its application to clinical research.
We focus on connective tissue diseases in three, overlapping research programmes. These programmes aim to understand:
This research theme links with other local, national and international centres of excellence and has close integration of basic and clinical researchers and hosts the only immunotherapy centre in the UK.
Genetic approaches to the individualisation of drug therapy, including anticoagulants and anti-cancer drugs, and in the genetics of diverse non-Mendelian diseases, from diabetes to periodontal disease, are a focus. A wide range of knowledge and experience in both genetics and clinical sciences is utilised, with access to high-throughput genotyping platforms.
Our scientists and clinicians use in situ cellular technologies and large-scale gene expression profiling to study the normal and pathophysiological remodelling of vascular and uteroplacental tissues. Novel approaches to cellular interactions have been developed using a unique human tissue resource. Our research themes include:
We also have preclinical molecular biology projects in breast cancer research.
We conduct a broad range of research activities into acute and chronic lung diseases. As well as scientific studies into disease mechanisms, there is particular interest in translational medicine approaches to lung disease, studying human lung tissue and cells to explore potential for new treatments. Our current areas of research include:
Our research projects are concerned with the harmful effects of chemicals, including prescribed drugs, and finding ways to prevent and minimise these effects. We are attempting to measure the effects of fairly small amounts of chemicals, to provide ways of giving early warning of the start of harmful effects. We also study the adverse side-effects of medicines, including how conditions such as liver disease and heart disease can develop in people taking medicines for completely different medical conditions. Our current interests include: environmental chemicals and organophosphate pesticides, warfarin, psychiatric drugs and anti-cancer drugs.
Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.
Veterinary epidemiology is a key component in a number of the global grand challenges relating to disease control, food security and climate change. Consequently, there is a need to improve our ability to understand, predict and respond to patterns and dynamics of disease and to control outbreaks.
The R(D)SVS and SRUC partnership creates the greatest concentration of research power in veterinary and agricultural sciences in the UK. The MSc draws on this wealth of experience and research activity to provide scientific knowledge of the fundamental biological processes (e.g. behaviour, physiology, immunology, ecology) and environmental and farming management practices (e.g. husbandry, nutrition, livestock trade) driving disease transmission, persistence, prevalence and spread in livestock production systems. This enables in-depth understanding of complex environmental patterns of disease, which facilitates prediction of disease risk and control. This multidisciplinary systems approach will provide you with the skills to make significant contributions to tackling food security, climate change and disease control in your role as an animal health professional.
By the end of the programme you will not only have a detailed understanding of the biology driving disease persistence and prevalence, but also how the biology scales up from individuals to populations. You will understand how this interacts with agricultural management practices to determine the efficacy of disease control strategies and livestock production (i.e. interdisciplinary systems thinking and communication). Furthermore, the systems approach offers a way to frame disease challenges and problem solve disease risk at a range of scales (e.g. from veterinarians tackling specific outbreaks to the consequences of climate change on disease risk). To this end the programme provides training in methodological skills for the design, implementation, analysis, interpretation and communication of epidemiological studies, disease surveillance and disease control in animal populations and wider host communities.
Courses are delivered by active researchers presenting their own research, which is placed into context with global grand challenges. As such, you will be exposed to and taught skills appropriate for developing a research career.
The programme will use the University’s award winning online learning environments, which includes video podcasts, web-based discussion forums and expert tuition.
The programme is delivered part-time by online learning over period of 3-6 years.
You may undertake the programme by intermittent study (flexible progression route), accruing credits within a time limit of:
The programme is modular in structure, offering a flexible student-centred approach to the choice of courses studied; other than the three core courses required for the certificate, students may choose to study individual courses, to complete a sufficient number of credits to be awarded the:
Postgraduate Professional Development
Postgraduate Professional Development (PPD) is aimed at working professionals who want to advance their knowledge through a postgraduate-level course(s), without the time or financial commitment of a full Masters, Postgraduate Diploma or Postgraduate Certificate.
You may take a maximum of 50 credits worth of courses over two years through our PPD scheme. These lead to a University of Edinburgh postgraduate award of academic credit. Alternatively, after one year of taking courses you can choose to transfer your credits and continue on to studying towards a higher award on a Masters, Postgraduate Diploma or Postgraduate Certificate programme. Although PPD courses have various start dates throughout a year you may only start a Masters, Postgraduate Diploma or Postgraduate Certificate programme in the month of September. Any time spent studying PPD will be deducted from the amount of time you will have left to complete a Masters, Postgraduate Diploma or Postgraduate Certificate programme.
The courses and programme as a whole will provide:
Our Microbiome in Health & Disease MSc provides students with a unique background in all aspects of both analysis of microbiome and determining the role of microbiome in pathology with experience in both computational and experimental techniques.
Designed and delivered by the newly established Centre for Host-Microbiome Interactions (CHMI) at King’s, the course brings together teaching on a varied course incorporating systems biology and bioinformatics with molecular biology, microbiology, immunology and physiology.
In the post-human genome project world, our health is dependent on more than our genes. High throughput sequencing reveals the amazing complexity and extent of the microbial communities that reside within or upon us. We are also beginning to understand just how dynamic the interactions between the host and members of communities are. Interactions are diverse, and variations observed between individuals depend on a multitude of microbial and host factors, including diet and inflammatory status. More importantly, it is becoming clear that different disease states are linked to significant changes in the make-up of these communities. Scientists who understand the computational analysis of the huge data sets for microbial communities, and who are also able to interpret findings in the context of human and microbial health, will be in demand across this emerging field in academia and in industry.
The MSc Microbiome in Health & Disease will provide you with a deep understanding of microbial communities and their diversity, and the impact of these communities on host health and disease. You will be exposed to the concepts and techniques involved in profiling and analysing large omics data sets associated with characterising and investigating microbial communities.
You will learn to analyse omics data sets, such as genome, transcriptome, metabolome and metagenome data, and how to integrate these data to develop a holistic understanding of the interactions between host and microbial communities in both health and disease states.
You will also learn how these skills apply in industry and have the opportunity to undertake research in collaboration with industrial partners. You will study the intersection between microbiome and engineering and learn how to identify and develop innovative products in different microbiome fields, applying learning from computational, multiomics analysis and basic biology, through advanced synthetic biology tools, and integrative analysis and modelling, to design new engineered therapeutic microbial communities and optimize their effectiveness in clinical, agricultural and environmental challenges.
You will also undertake a 10,000 word supervised dissertation on a subject within the field of microbiome in health and disease.
The course aims to develop students' knowledge of the microbial communities that reside within or upon us, and how they impact our health and disease processes.
It is designed for students who wish to improve their background knowledge and skills prior to applying for a PhD studentship, and also for students who wish to enhance their knowledge and skill set for analysing and interpreting the large, multiple omics data sets that are involved in microbiome research.
The MSc Microbiome in Health & Disease consists of 4 taught modules (two covering microbiology, microbial diversity and host-microbiome interactions, and two covering computational analysis of microbiome, and systems and synthetic biology), followed by a lab-based research project. The taught component will run from September until January, with the research component running from February until August.
Teaching comprises conventional lectures, tutorials and computational workshops, supported by example sessions, project work and independent learning via reading material and online courses. During the computational modules, you will be provided with data sets to analyse for written and oral projects.
After completing the taught component, you will undertake a lab-based research project for which you will provide a proposal and subsequent dissertation and presentation under the guidance of a supervisor.
The typical hours you will spend as you progress through your studies are as follows:
Lectures, seminars & feedback: 214 hours
Self-study: 1586 hours
Contact time is based on 24 academic weeks and self-study time is based on 31 academic weeks.
Typically, one credit equates to 10 hours of work.
You may typically expect assessment by a combination of coursework (76%) and examinations (24%).
The study time and assessment methods detailed above are typical and give you a good indication of what to expect. However, they may change if the course modules change.
The need to develop new strategies to combat diseases remains a major global challenge. This degree aims to enhance your employability and prepare you to tackle this challenge.
We’ll give you advanced training in the mechanisms underpinning a spectrum of infectious and non-infectious diseases, including viral, bacterial and parasitic infections, cancer, neurodegeneration, cardiovascular disease and chromosomal abnormalities. You’ll also explore current and emerging diagnostic and treatment strategies.
You’ll learn about the latest molecular, genetic and cellular approaches being used to understand, diagnose and treat human disease, including traditional methods such as polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA), and novel methods involving genome and proteome analysis.
You’ll also have the opportunity to investigate the role of the immune system in the response to infection and disease, covering topics such as innate and adaptive immunity, allergy and immune evasion.
If you choose to study at Leeds, you’ll join a faculty ranked 6th in the UK for its research impact in the recent Research Excellence Framework (REF 2014), and you’ll graduate with the solid base of scientific knowledge and specialist skills highly valued by employers.
On this course you’ll gain an overview of a range of modern techniques and methodologies that underpin contemporary biomolecular sciences. You’ll investigate five topic areas: molecular biology, structural biology, cell imaging and flow cytometry, high throughput techniques and transgenic organisms.
You’ll also apply your knowledge to an extended practical investigation in the form of a laboratory-based project, involving practical training in a range of modern molecular biology and protein engineering techniques such as gene cloning, PCR, mutagenesis, protein expression, protein purification and analysis.
To help you to develop and specialise, you’ll get substantial subject-specific training through an independent research project in an area of infection, immunity or human disease.
You’ll also take specialist taught modules covering topics such as infectious and non-infectious disease, advanced immunology, medical diagnostics and treatment of infectious diseases and cancer.
If you have previous experience of immunology, you could opt to investigate the structure, regulation and development of the pharmaceutical manufacturing sector, or explore aspects of human toxicology. These could include the actions of toxicants on the cardiovascular, immune and nervous systems, kidneys, liver and lungs, genetic toxicology and chemical carcinogenesis, and the effects of chemicals on fetal development.
In the final part of the course you'll work on an independent laboratory-based research project related to your course options. You’ll receive extensive training in experimental design, the practical use of advanced techniques and technologies, data analysis and interpretation, and will be assigned a research project supervisor who will support and guide you through your project.
These are typical modules/components studied and may change from time to time. Read more in our Terms and conditions.
You’ll have access to the very best learning resources and academic support during your studies. We’ve been awarded a Gold rating in the Teaching Excellence Framework (TEF, 2017), demonstrating our commitment to delivering consistently outstanding teaching, learning and outcomes for our students.
Your learning will be heavily influenced by the University’s world-class research as well as our strong links with highly qualified professionals from industry, non-governmental organisations and charities.
You’ll experience a wide range of teaching methods including formal lectures, interactive workshops, problem-solving, practical classes and demonstrations.
Through your research project and specialist modules, you’ll receive substantial subject-specific training. Our teaching and assessment methods are designed to develop you into a scientist who is able to think independently, solve problems, communicate effectively and demonstrate a high level of practical ability.
We use a variety of assessment methods: multiple-choice testing, practical work, data handling and problem solving exercises, group work, discussion groups (face-to-face and online), computer-based simulation, essays, posters and oral presentations.
The strong research element of the Infection, Immunity and Human Disease MSc, along with the specialist and generic skills you develop, mean you’ll graduate equipped for a wide range of careers.
Our graduates work in a diverse range of areas, ranging from bioscience-related research through to scientific publication, teacher training, health and safety and pharmaceutical market research.
Links with industry
We have a proactive Industrial Advisory Board who advise us on what they look for in graduates and on employability-related skills within our programmes.
We collaborate with a wide range of organisations in the public and commercial sectors. Many of these are represented on our Industrial Advisory Board. They include:
Industrial research placements
Some of our partners offer MSc research projects in their organisations, allowing students to develop their commercial awareness and build their network of contacts.
Professional and career development
We take personal and career development very seriously. We have a proactive Industrial Advisory Board who advises us on what they look for in graduates and on employability related skills within our courses.
Our dedicated Employability and Professional Development Officer ensures that you are aware of events and opportunities to increase your employability. In addition, our Masters Career Development Programme will support you to:
The Cell Signalling in Health and Disease MRes is a research-based qualification with a taught component that is of an equivalent standard to an MSc. The course provides a springboard into a career that involves a working knowledge of scientific research in academia and industry.
The course is designed for graduates with a BSc in the life sciences or other science disciplines, and for intercalating and fully qualified MBBS or BDS students. It can be taken either as a stand-alone qualification or as an entry route onto a PhD or MD.
The taught component of the course includes subject-specific content in the area of cell signalling in health and disease. You have the flexibility to develop your own bespoke course by selecting additional, complementary modules. You will also participate in training in general research principles, and other professional and key skills.
Your research project comprises the major element of the course. This project will involve 24 weeks of research in an area of cell signalling in health and disease under the supervision of an expert academic researcher in the field.
The course allows you to experience an internationally competitive research area, predominantly in academia but also potentially in industry.
Cell Signalling in Health and Disease MRes is closely linked to a suite of MRes courses that you may also be interested in:
Our Medical Sciences Graduate School is dedicated to providing you with information, support and advice throughout your research degree studies. We can help and advise you on a variety of queries relating to your studies, funding or welfare.
Our Research Student Development Programme supports and complements your research whilst developing your professional skills and confidence.
You will make an on-going assessment of your own development and training needs through personal development planning (PDP) in the ePortfolio system. Our organised external events and development programme have been mapped against the Vitae Researcher Development Framework to help you identify how best to meet your training and development needs.
Postgraduate Loans are now Open for Home/EU students - https://www.gov.uk/postgraduate-loan/how-to-apply
Scholarships & Discounts available
This programme provides advanced contemporary training in parasitology and the study of disease vectors. The broad scope of the programme ranges from the biology, immunology, ecology and population biology of the organisms to public health, disease epidemiology and tropical health issues. In addition to providing a solid foundation in parasite and vector biology, the programme provides practical experience of essential techniques, as well as significant theoretical and practical knowledge in all important and topical areas of the field. Following the taught component, participants complete a dissertation including a period of applied research either overseas or in Liverpool.
LSTM education courses are taught within a dynamic environment by staff working at the cutting-edge of research in tropical medicine and global health. They are designed to enable the professional development of the student, to be relevant to students from both the UK and overseas and to promote approaches to study that will enable students to continue their learning into the future.
This course aims to:
To equip students with the knowledge and practical skills needed to develop a career in research, training or control of parasitic and vector-borne diseases.
To provide practical experience of a range of specialised technical and analytical skills relevant to the study of parasites and disease vectors.
To enable students to conduct independent research in the laboratory and/or field.
To produce graduates who are experienced, committed, informed, proactive and effective professionals, capable of taking substantial and leading professional roles.
To facilitate high quality learning that is informed by critical analysis of current research.
To develop independent and reflective approaches to study that will enable graduates to continue to learn in the future.
Over many years, we have educated hundreds of Masters students, many of whom have established successful careers in research in the academic or private sectors, or who have gone on to work in development as part of government or NGO teams. Graduates of the MSc Biology & Control of Parasites and Disease Vectors typically follow careers in research (some in LSTM) or training in areas related to the control of infectious disease, in particular parasitic and vector-borne tropical diseases. Other careers paths have led to teacher training, working overseas for NGO’s, military and public health-related careers.