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Masters Degrees (Disease)

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The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents. Read more
The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents.

Degree Information

The programme provides a thorough grounding in modern approaches to the understanding of the genetics of disease alongside the cutting-edge research methods and techniques used to advance our understanding of development of disease. Core modules provide a broad coverage of the genetics of disease, research skills and social aspects, whilst specialised streams in Inherited Diseases, Pharmacogenetics and Computational Genomics, in which students can qualify, and the research project allow more in-depth analysis in areas of genetics.

Students undertake modules to the value of 180 credits.

The programme consists of four core modules (60 credits) and two specialist modules (30 credits) and a research project culminating in a dissertation (90 credits).

A Postgraduate Diploma consisting of six modules (four core modules in term one and two modules within the selected stream in term two) is offered, full-time nine months.

A Postgraduate Certificate consisting of four core modules in term one (60 credits) is offered, full-time three months.

Core Modules
- Advanced Human Genetics: Research Principles
- Human Genetics in Context
- Core Skills
- Basic Statistics for Medical Sciences

Specialist modules
In term two you will take specialist modules depending on the specialist stream you select: Inherited Disease (A); Pharmacogenetics (B); Computational Genomics (C).
- Applications in Human Genetics (A)
- Either Genetics of Cardiovascular Disease or Genetics of Neurological Disease (A)
- Clinical Applications of Pharmacogenetic Tests (B)
- Anti-Cancer Personalised Medicine or Pharmacogenomics, Adverse Drug Reactions and Biomarkers (B)
- Applications in Human Genetics (C)
- Statistics for Interpreting Genetic Data (C)

Dissertation/report
Students undertake an original research project investigating topical questions in genetics and genetics of human disease which culminates in a dissertation of 12,000 to 14,000 words and an oral presentation.

Teaching and learning
Students develop their knowledge and understanding of genetics of human diseases through a combination of lectures, seminars, tutorials, presentations and journal clubs. Taught modules are assessed by unseen written examination and/or, written reports, oral presentations and coursework. The research project is assessed by the dissertation and oral presentation.

Careers

Advanced training in genetic techniques including bioinformatic and statistical approaches positions graduates well for PhD studentships in laboratories using genetic techniques to examine diseases such as heart disease, cancer and neurological disorders. Another large group will seek research jobs in the pharmaceutical industry, or jobs related to genetics in healthcare organisations.

Employability
The MSc in Genetics of Human Disease facilitates acquisition of knowledge and skills relevant to a career in research in many different biomedical disciplines. About half of our graduates enter a research career by undertaking and completing PhDs and working as research associates/scientists in academia. Some of our graduates go on to jobs in the pharmaceutical industry, while others enter careers with clinical genetic diagnosis services, particularly in molecular genetics, in healthcare organisations and hospitals around the world. Those graduates with a prior medical training often utilise their new skills as clinical geneticists.

Why study this degree at UCL?

UCL is in a unique position to offer both the basic science and application of modern genetics to improve human health. The programme is a cross-faculty initiative with teaching from across the School of Life and Medical Sciences (SLMS) at UCL.

Students will be based at the UCL Genetics Institute (UGI), a world-leading centre which develops and applies biostatistical and bioinformatic approaches to human and population genetics. Opportunities to conduct laboratory or computational-based research projects are available in the laboratories of world-leading geneticists affiliated to the UGI.

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Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research. Read more

Understanding the molecular basis of disease

Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research.

Only by dissecting the molecular mechanisms that trigger and advance diseases and dysfunctions can we design effective treatments and medicines. The Research Master's in Molecular Mechanisms of Disease (MMD) offers you an intensive two-year programme that provides you with in-depth knowledge and research experience of disease-related molecular mechanisms. In addition, you will acquire skills such as academic writing and presentation skills and learn how to successfully apply for grants and market yourself.

Passion for molecular biomedical research

As an MMD student you will be part of the unique research community that is found within the Radboud Institute for Molecular Life Sciences (RIMLS). Like you, RIMLS researchers have a strong passion for research. They will assist you throughout the programme with guidance and expertise, supporting you in acquiring knowledge and developing excellent research skills. The RIMLS is one of the research institutes of the Radboud university medical center, so their research is closely linked to the clinic and thus aimed at translating results into treatments for patients. Examples include the translation of insights into the biology of antigen-presenting cells into new immunological cancer therapies and understanding the mutations underlying blindness into the development of gene therapies for patients with inherited blindness.

See the website http://www.ru.nl/masters/mmd

Why study Molecular Mechanisms of Disease at Radboud University?

- You will follow a broad biomedical programme that allows you to specialise in your specific field-of-interest.
- You will have intense daily contact with established researchers.
- You will participate in group-oriented education and be part of a small group of highly motivated national and international students.
- A personal mentor will help you to reflect on your study programme and career perspective.
- You will do two 6-months research internships one of which will be abroad.
- There is a 92% pass rate of MMD students within the two years.
- International MMD students can apply for scholarships from the Radboudumc Study Fund.

Career prospects

There is considerable demand for experts in the molecular biomedical sciences as well as in their application to the development of treatments for diseases such as cancer, autoimmune and inflammatory disorders, and metabolic diseases.

Graduates in MMD are equipped with cutting-edge knowledge of multidisciplinary research in the mechanisms of disease and in state-of-the-art diagnostic methods and technologies. During the programme, you will develop a highly critical, independent approach to problem-solving. You will also acquire the basic management skills needed to lead R&D projects in the biotechnology and pharmaceutical industries.

Most of our graduates will enter an international PhD programme to continue with research in academia or industry.

PhD opportunities

The MSc Molecular Mechanisms of Disease aims to provide all skills and knowledge necessary to rapidly enter an international PhD programme. In the Netherlands and many places in Europe, it is impossible to start a PhD programme directly after obtaining a Bachelor's degree. This research Master’s programme seriously increases your chances for obtaining an excellent PhD training position by giving you a mature perspective and a broad range of experimental approaches. In fact, over 90% of our graduates has started a (funded) PhD project.

The Radboud Institute for Molecular Life Sciences (RIMLS) recruits about fifty PhD students a year. MMD graduates are excellent candidates for these positions. Furthermore, the Radboud university medical centre offers the opportunity for its research-oriented Master's students to write their own research project. The best candidates are awarded a fully funded four-year PhD studentship at the department of their choice.

Our approach to this field

The molecular regulation of cellular processes is crucial for human development, and maintenance of health throughout life. It's evident that cellular malfunction is the cause of common multi-factorial diseases such as diabetes, immune and inflammatory disorders, renal disease, cardiovascular, metabolic and neurodegenerative diseases as well as obesity and cancer.

The Radboud Institute for Molecular Life Sciences (RIMLS) Graduate School plays a key role in developing new therapies for the fight against such diseases. RIMLS aims to improve diagnostics and develop new treatments by generating basic knowledge in the molecular biomedical life sciences and translating it into clinical application and experimental research in patients.

The RIMLS – which is part of Radboud university medical center – offers an exclusive Master's programme in Molecular Mechanisms of Disease. Top researchers and clinicians teach the programme.

Key themes

The MMD programme is organised along three major educational themes which reflect the main research areas present in the RIMLS and which each include both a fundamental and a disease-related aspect:
- Theme 1 Infection, Immunity and Regenerative Medicine / Immunity-related Disorders and Immunotherapy
- Theme 2 Metabolism, Transport and Motion / Metabolic Disorders
- Theme 3 Cell Growth and Differentiation / Developmental Disorders and Malignancies

See the website http://www.ru.nl/masters/mmd

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The burden of chronic disease in our society is growing, and innovative methods and highly trained individuals are needed to successfully tackle the problem from all sides. Read more
The burden of chronic disease in our society is growing, and innovative methods and highly trained individuals are needed to successfully tackle the problem from all sides. This vocational degree provides students with the opportunity to enhance their skills, knowledge and understanding of facilitating, managing and supporting behaviour change at individual, group and population levels.

There is a need, in a range of public health settings, such as clinical, healthcare, social care or public health departments for highly skilled, autonomous and analytical employees specialising in the prevention, assessment and management of chronic diseases.

The MSc in Chronic Disease Management at St Mary’s University is rooted in developing your skills at promoting and supporting behaviour change, expanding your research expertise, equipping you to obtain a Public Health Skills and Knowledge Framework Passport, and enhancing your ability to tackle chronic disease in individuals and through public bodies. This course is ideal for those looking to progress their career within their current organisation, or provide the vital skills and experience necessary to embark on a career working with individuals and groups to tackle chronic disease.

Why St Mary's?

The structure of the course embeds a work placement into the programme, allowing students to bridge the gap between theoretical knowledge and hands-on experience as they progress through their studies. This enables students to observe and work within a professional environment working in high level sport or clinical settings providing an insight into the demands of helping people to make lifestyle improvements in roles they may wish to fulfil upon graduating.

The degree is underpinned by a detailed understanding of theoretical and practical approaches to behaviour change, a detailed appreciation of public health frameworks, and lifestyle management including nutrition and physical activity to manage and prevent chronic disease. St Mary’s University maintains fantastic links with local health, educational, social care and charity organisations through the Centre for Work-Based Learning and the University’s own Health and Wellbeing Centre. This course operates a blended learning approach that is suitable for those completing the course alongside existing work commitments and also those who wish to focus solely on their study. We use cutting edge technology to ensure tutor and peer support is maximised on campus and through distance learning.

Course Content

The course has three possible exit points. Successfully completing 60 credits worth of modules gains the Postgraduate Certificate. Successfully completing 120 credits, gains the Postgraduate Diploma and the full Masters is awarded on successful completion of 180 credits, comprising six taught modules plus a 13,000 word dissertation of the requisite quality. Module details are below:
-Public Health and Prevention of Chronic Disease (Optional)
-Behaviour Change for Lifestyle Management (Core)
-Nutrition and Chronic Disease Management (Optional)
-Physical Activity and Chronic Disease Management (Optional )
-Work-based Learning and Professional Issues in Healthcare (Core)
-Research Methods (Core)
-Self-care, Mindfulness and Patient Empowerment (Optional)
-Research Dissertation (Core)

The teaching will be delivered using a combination of a few intensive week-long blocks spread throughout the year and blended learning involving bi-monthly on-site teaching and on-line seminars and discussion. There will be a time-commitment for 8 mid-week sessions per semester and 4 of these will require on-site attendance. Students will participate in regular on-line discussion throughout the course. An additional 15 day commitment is required for completion of the embedded work placement. A number of different work formats are available for the work placement and students working in relevant areas may be able to complete this in their current workplace. Assessment is by on-line discussion, essays, case studies, reflective accounts, presentations, practical assessment, evaluative report and research dissertation.

Career Prospects

Integral to all parts of the course is the development of skills and competencies in areas highlighted as a priority by Public Health England. This will include preventative approaches and tackling emerging conditions early, engaging hard to reach groups in the prevention and management of chronic disease, including males, ethnic minorities, pregnant women, the elderly and those from low socio-economic groups. They will be informed by the competencies put forward in the Public Health Skills and Knowledge Framework at Level 7. The course will include a work-based learning component whereby students are involved in the planning, implementation and evaluation of a particular project and this will place graduates in a favourable position to climb the career ladder in organisations with a chronic disease focus.

Please note: This programme will not be running in September 2017.

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Veterinary epidemiology is a key component in a number of the global grand challenges relating to disease control, food security and climate change. Read more

Veterinary epidemiology is a key component in a number of the global grand challenges relating to disease control, food security and climate change. Consequently, there is a need to improve our ability to understand, predict and respond to patterns and dynamics of disease and to control outbreaks.

The R(D)SVS and SRUC partnership creates the greatest concentration of research power in veterinary and agricultural sciences in the UK. The MSc draws on this wealth of experience and research activity to provide scientific knowledge of the fundamental biological processes (e.g. behaviour, physiology, immunology, ecology) and environmental and farming management practices (e.g. husbandry, nutrition, livestock trade) driving disease transmission, persistence, prevalence and spread in livestock production systems. This enables in-depth understanding of complex environmental patterns of disease, which facilitates prediction of disease risk and control. This multidisciplinary systems approach will provide you with the skills to make significant contributions to tackling food security, climate change and disease control in your role as an animal health professional.

By the end of the programme you will not only have a detailed understanding of the biology driving disease persistence and prevalence, but also how the biology scales up from individuals to populations. You will understand how this interacts with agricultural management practices to determine the efficacy of disease control strategies and livestock production (i.e. interdisciplinary systems thinking and communication). Furthermore, the systems approach offers a way to frame disease challenges and problem solve disease risk at a range of scales (e.g. from veterinarians tackling specific outbreaks to the consequences of climate change on disease risk). To this end the programme provides training in methodological skills for the design, implementation, analysis, interpretation and communication of epidemiological studies, disease surveillance and disease control in animal populations and wider host communities.

Courses are delivered by active researchers presenting their own research, which is placed into context with global grand challenges. As such, you will be exposed to and taught skills appropriate for developing a research career.

Online learning

The programme will use the University’s award winning online learning environments, which includes video podcasts, web-based discussion forums and expert tuition.

Programme structure

The programme is delivered part-time by online learning over period of 3-6 years.

You may undertake the programme by intermittent study (flexible progression route), accruing credits within a time limit of:

  • 1 years for the Certificate (maximum period 2 years)
  • 2 years for the Diploma (maximum period 4 years)
  • 3 years for the MSc (maximum period of 6 years including a maximum period of 12 months from the start of your written reflective element to it being completed)

The programme is modular in structure, offering a flexible student-centred approach to the choice of courses studied; other than the three core courses required for the certificate, students may choose to study individual courses, to complete a sufficient number of credits to be awarded the:

  • Certificate (60 credits)
  • Diploma (120 credits)
  • MSc (180 credits)

Postgraduate Professional Development

Postgraduate Professional Development (PPD) is aimed at working professionals who want to advance their knowledge through a postgraduate-level course(s), without the time or financial commitment of a full Masters, Postgraduate Diploma or Postgraduate Certificate.

You may take a maximum of 50 credits worth of courses over two years through our PPD scheme. These lead to a University of Edinburgh postgraduate award of academic credit. Alternatively, after one year of taking courses you can choose to transfer your credits and continue on to studying towards a higher award on a Masters, Postgraduate Diploma or Postgraduate Certificate programme. Although PPD courses have various start dates throughout a year you may only start a Masters, Postgraduate Diploma or Postgraduate Certificate programme in the month of September. Any time spent studying PPD will be deducted from the amount of time you will have left to complete a Masters, Postgraduate Diploma or Postgraduate Certificate programme.

Learning outcomes

  • Acquire knowledge about disease systems in livestock production environments and the interactions between the biological and livestock management processes driving disease dynamics.
  • Acquire specific skills to link individual farm environments and management practices to disease risk and production efficiency at farm and national scales.
  • Be able to interpret, be critical of and communicate scientific results and information in research.

Career opportunities

The courses and programme as a whole will provide:

  • general postgraduate training (e.g. for people in education, government, policy-making, agricultural and veterinary organisations) to enable promotion, further employment opportunities or personal fulfilment
  • general postgraduate training for people considering a career in research (e.g. a precursor to a PhD)
  • topic-specific postgraduate training (e.g. for veterinarians for continuing professional development) to enable promotion, further employment opportunities or personal fulfilment


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The need to develop new strategies to combat diseases remains a major global challenge. This degree aims to enhance your employability and prepare you to tackle this challenge. Read more

The need to develop new strategies to combat diseases remains a major global challenge. This degree aims to enhance your employability and prepare you to tackle this challenge.

We’ll give you advanced training in the mechanisms underpinning a spectrum of infectious and non-infectious diseases, including viral, bacterial and parasitic infections, cancer, neurodegeneration, cardiovascular disease and chromosomal abnormalities. You’ll also explore current and emerging diagnostic and treatment strategies.

You’ll learn about the latest molecular, genetic and cellular approaches being used to understand, diagnose and treat human disease, including traditional methods such as polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA), and novel methods involving genome and proteome analysis.

You’ll also have the opportunity to investigate the role of the immune system in the response to infection and disease, covering topics such as innate and adaptive immunity, allergy and immune evasion.

If you choose to study at Leeds, you’ll join a faculty ranked 6th in the UK for its research impact in the recent Research Excellence Framework (REF 2014), and you’ll graduate with the solid base of scientific knowledge and specialist skills highly valued by employers.

Course content

On this course you’ll gain an overview of a range of modern techniques and methodologies that underpin contemporary biomolecular sciences. You’ll investigate five topic areas: molecular biology, structural biology, cell imaging and flow cytometry, high throughput techniques and transgenic organisms.

You’ll also apply your knowledge to an extended practical investigation in the form of a laboratory-based project, involving practical training in a range of modern molecular biology and protein engineering techniques such as gene cloning, PCR, mutagenesis, protein expression, protein purification and analysis.

To help you to develop and specialise, you’ll get substantial subject-specific training through an independent research project in an area of infection, immunity or human disease.

You’ll also take specialist taught modules covering topics such as infectious and non-infectious disease, advanced immunology, medical diagnostics and treatment of infectious diseases and cancer.

If you have previous experience of immunology, you could opt to investigate the structure, regulation and development of the pharmaceutical manufacturing sector, or explore aspects of human toxicology. These could include the actions of toxicants on the cardiovascular, immune and nervous systems, kidneys, liver and lungs, genetic toxicology and chemical carcinogenesis, and the effects of chemicals on fetal development.

In the final part of the course you'll work on an independent laboratory-based research project related to your course options. You’ll receive extensive training in experimental design, the practical use of advanced techniques and technologies, data analysis and interpretation, and will be assigned a research project supervisor who will support and guide you through your project.

Course structure

These are typical modules/components studied and may change from time to time. Read more in our Terms and conditions.

Compulsory modules

  • Advanced Immunology 10 credits
  • Infectious & Non-infectious Diseases 10 credits
  • Practical Bioinformatics 10 credits
  • Medical Diagnostics 10 credits
  • MSc Bioscience Research Project Proposal 5 credits
  • Treatment of Infectious Disease and Cancer 10 credits
  • Research Planning and Scientific Communication 10 credits
  • Advanced Biomolecular Technologies 20 credits
  • Protein Engineering Laboratory Project 15 credits
  • Bioscience MSc Research Project 80 credits

For more information on typical modules, read Infection, Immunity and Human Disease MSc in the course catalogue

Learning and teaching

You’ll have access to the very best learning resources and academic support during your studies. We’ve been awarded a Gold rating in the Teaching Excellence Framework (TEF, 2017), demonstrating our commitment to delivering consistently outstanding teaching, learning and outcomes for our students.

Your learning will be heavily influenced by the University’s world-class research as well as our strong links with highly qualified professionals from industry, non-governmental organisations and charities.

You’ll experience a wide range of teaching methods including formal lectures, interactive workshops, problem-solving, practical classes and demonstrations.

Through your research project and specialist modules, you’ll receive substantial subject-specific training. Our teaching and assessment methods are designed to develop you into a scientist who is able to think independently, solve problems, communicate effectively and demonstrate a high level of practical ability.

Assessment

We use a variety of assessment methods: multiple-choice testing, practical work, data handling and problem solving exercises, group work, discussion groups (face-to-face and online), computer-based simulation, essays, posters and oral presentations.

Career opportunities

The strong research element of the Infection, Immunity and Human Disease MSc, along with the specialist and generic skills you develop, mean you’ll graduate equipped for a wide range of careers.

Our graduates work in a diverse range of areas, ranging from bioscience-related research through to scientific publication, teacher training, health and safety and pharmaceutical market research.

Links with industry

We have a proactive Industrial Advisory Board who advise us on what they look for in graduates and on employability-related skills within our programmes.

We collaborate with a wide range of organisations in the public and commercial sectors. Many of these are represented on our Industrial Advisory Board. They include:

  • GlaxoSmithKline
  • Ernst and Young
  • The Food and Environment Research Agency
  • The Health Protection Agency
  • MedImmune
  • Thermofisher Scientific
  • Hays Life Sciences
  • European Bioinformatics Institute
  • Smaller University spin-out companies, such as Lumora

Industrial research placements

Some of our partners offer MSc research projects in their organisations, allowing students to develop their commercial awareness and build their network of contacts.

Professional and career development

We take personal and career development very seriously. We have a proactive Industrial Advisory Board who advises us on what they look for in graduates and on employability related skills within our courses.

Our dedicated Employability and Professional Development Officer ensures that you are aware of events and opportunities to increase your employability. In addition, our Masters Career Development Programme will support you to:

  • explore career options and career planning
  • understand the PhD application process and optimise PhD application
  • learn how to use LinkedIn and other social media for effective networking and career opportunities
  • practice interviews for both job and PhD applications.


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The World Health Organisation Global Burden of Disease Study has shown that non-communicable chronic disease accounts for ~ 60% of deaths globally. Read more
The World Health Organisation Global Burden of Disease Study has shown that non-communicable chronic disease accounts for ~ 60% of deaths globally. Major contributors include cardiovascular disease, chronic obstructive pulmonary disease and chronic kidney disease. Inflammation is the central driving force in much of this burden of chronic degenerative disease. This MSc course is therefore designed to integrate current cutting-edge research in the fields of molecular and cellular biology and immunology and use this to demonstrate:

- The fundamental processes of inflammation
- The molecular and cellular mechanisms of disease progression that are driven by inflammation

The course is carefully integrated and combines up-to-date practical and theoretical teaching methods to prepare students for careers in postgraduate biomedical research, medicine, and the bio-pharmaceutical industry.

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The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Read more
The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Research areas include: genetic medicine, developmental genetics, neuromuscular and neurological genetics, mitochondrial genetics and cardiovascular genetics.

As a research postgraduate in the Institute of Genetic Medicine you will be a member of our thriving research community. The Institute is located in Newcastle’s Life Science Centre. You will work alongside a number of research, clinical and educational organisations, including the Northern Genetics Service.

We offer supervision for MPhil in the following research areas:

Cancer genetics and genome instability

Our research includes:
-A major clinical trial for chemoprevention of colon cancer
-Genetic analyses of neuroblastoma susceptibility
-Research into Wilms Tumour (a childhood kidney cancer)
-Studies on cell cycle regulation and genome instability

Cardiovascular genetics and development

We use techniques of high-throughput genetic analyses to identify mechanisms where genetic variability between individuals contributes to the risk of developing cardiovascular disease. We also use mouse, zebrafish and stem cell models to understand the ways in which particular gene families' genetic and environmental factors are involved in the normal and abnormal development of the heart and blood vessels.

Complex disease and quantitative genetics

We work on large-scale studies into the genetic basis of common diseases with complex genetic causes, for example autoimmune disease, complex cardiovascular traits and renal disorders. We are also developing novel statistical methods and tools for analysing this genetic data.

Developmental genetics

We study genes known (or suspected to be) involved in malformations found in newborn babies. These include genes involved in normal and abnormal development of the face, brain, heart, muscle and kidney system. Our research includes the use of knockout mice and zebrafish as laboratory models.

Gene expression and regulation in normal development and disease

We research how gene expression is controlled during development and misregulated in diseases, including the roles of transcription factors, RNA binding proteins and the signalling pathways that control these. We conduct studies of early human brain development, including gene expression analysis, primary cell culture models, and 3D visualisation and modelling.

Genetics of neurological disorders

Our research includes:
-The identification of genes that in isolation can cause neurological disorders
-Molecular mechanisms and treatment of neurometabolic disease
-Complex genetics of common neurological disorders including Parkinson's disease and Alzheimer's disease
-The genetics of epilepsy

Kidney genetics and development

Kidney research focuses on:
-Atypical haemolytic uraemic syndrome (aHUS)
-Vesicoureteric reflux (VUR)
-Cystic renal disease
-Nephrolithiasis to study renal genetics

The discovery that aHUS is a disease of complement dysregulation has led to a specific interest in complement genetics.

Mitochondrial disease

Our research includes:
-Investigation of the role of mitochondria in human disease
-Nuclear-mitochondrial interactions in disease
-The inheritance of mitochondrial DNA heteroplasmy
-Mitochondrial function in stem cells

Neuromuscular genetics

The Neuromuscular Research Group has a series of basic research programmes looking at the function of novel muscle proteins and their roles in pathogenesis. Recently developed translational research programmes are seeking therapeutic targets for various muscle diseases.

Stem cell biology

We research human embryonic stem (ES) cells, germline stem cells and somatic stem cells. ES cell research is aimed at understanding stem cell pluripotency, self-renewal, survival and epigenetic control of differentiation and development. This includes the functional analysis of genes involved in germline stem cell proliferation and differentiation. Somatic stem cell projects include programmes on umbilical cord blood stem cells, haematopoietic progenitors, and limbal stem cells.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.

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*Please note that it is our intention to transform this programme into a new programme Biology of Cardiovascular Disease from September 2017 onwards. Read more
*Please note that it is our intention to transform this programme into a new programme Biology of Cardiovascular Disease from September 2017 onwards. The option to focus on areas other than cardiovascular disease then will be limited.*

The Master's in Biology of Disease focuses on the translation of disease into a scientifically secure experiment/model, in order to study its underlying mechanisms and reveal potential therapies.

The Master's programme in Biology of Disease offers the opportunity to study disease mechanisms in the broadest sense via internships in pre-clinical and clinical research in medical, biomedical, biological, industrial and veterinary labs; and to focus on more than one clinical specialty enabling you to conduct research projects on different subjects and diseases. Alternatively this programme offers the possibility to focus on cardiovascular research.

This two year research programme comprises theoretical courses, elective courses, seminars, a major and minor research project, and the writing of a Master's thesis. The core component of this two year research programme consists of independently planning and conducting the two research projects, which will take 15 months in total. The minor research project may be completed elsewhere in the Netherlands or abroad; or it may be replaced by a specific profile: Management, Teaching and Communication or Drug Regulatory Sciences. Graduates of this programme are prepared for PhD studies (approximately 65% choose for this option); or to take on a position in the medical-technical or pharmaceutical industry, or in science journalism.

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Medical Life Sciences is an English-taught two-year Master’s programme in molecular disease research and bridges the gap between the sciences and medical studies. Read more
Medical Life Sciences is an English-taught two-year Master’s programme in molecular disease research and bridges the gap between the sciences and medical studies. You will get to know clinical research from scratch; you will learn how to investigate diseases/disease mechanisms both in ancient and contemporary populations, how to translate research results into prevention, diagnosis and therapies of diseases.
From the basics of medical science to lab experiments for the Master’s thesis, individual scientific training takes first priority. Experimental work in state-of-the-art research labs is essential in Medical Life Sciences; clinical internships, data analysis, lectures, seminars and electives complement the Medical Life Sciences curriculum.
Evolutionary biology will train you in thinking from cause to consequence. Molecular paleopathology and ancient DNA research tell you a lot about disease through human history. These insights help to fight disease today, which is why evolutionary medicine is becoming a cutting-edge research field. Whether you want to focus on ancient populations and paleopathology or on specific disease indications nowadays, here you get the tools and skills to do both.
To lay the foundation for working in medical research, Medical Life Sciences includes courses on clinical manifestations of diseases, molecular pathology and immunology. Hands-on courses in molecular biology, bioinformatics, clinical cell biology, medical statistics, and human genetics broaden your knowledge and make the interfaces between medicine and the sciences visible. You will learn how to acquire knowledge, verify and use it.. That biomedicine has many facets to discover is the great thing that keeps students fascinated and well-equipped for finding a job in academia or the industry.

Focus Areas

From the second semester, you additionally specialise in one of the following focus areas:

INFLAMMATION takes you deep into the molecular mechanisms of chronic inflammatory diseases, the causal network between inflammatory processes and disease, genetics and environment. New research results for prevention, diagnosis and therapy will be presented and discussed. An internship in specialised clinics helps to see how “bed to bench side”, i.e. translational medicine, works.

EVOLUTIONARY MEDICINE looks at how interrelations between humans and their environment have led to current disease susceptibility. Why do we suffer from chronic diseases such as diabetes, heart disease and obesity? Is our lifestyle making us sick? Why are certain genetic variants maintained in populations despite their disease risk? Evolutionary medicine focuses on bridging the gap between evolutionary biology and medicine by considering the evolutionary origins of common diseases to help find new biomedical approaches for preventing and treating them.

ONCOLOGY delves deep into molecular research on malignant diseases, the interplay of genetics and environment, cell biology of tumours, and many other aspects. You will achieve a better understanding of unresolved problems and opportunities of current research approaches.

LONGEVITY focuses on molecular mechanisms that seem to counteract the detrimental effect of ageing. The disease resilience and metabolic stability of extraordinarily fit people well over 90 years of age are of special interest. This research is complemented by experiments on model organisms. You will also look at the molecular pathways of ageing, and which role genes and the environment play. How the intricate web of counteracting effects triggering ageing and/or longevity works stands as the central focus of this area.

Scientists and clinicians will make you familiar with these topics in lectures and seminars. You will discuss different research approaches, perspectives and the latest developments in medical research. Lab practicals in state-of-the-art research labs, a lab project, and the experimental Master's thesis will provide ample opportunity to be involved in real-time research projects.

Electives

To widen your perspective, you choose one of three electives designed to complement the focus areas. The schedules are designed so that you can take part in more than one elective if places are available. Tracing Disease through Time looks at disease etiology by analysing biomolecules, diets and pathogens in archaeological specimens. You may opt for Epidemiology to immerse yourself in epidemiological approaches with special emphasis on cardiovascular diseases, one of the greatest health threats in modern societies. Another option is Molecular Imaging, which gives you insight into the world of high-tech imaging in medical research.

Additional electives such as Neurology, Tissue Engineering or Epithelial Barrier Functions and Soft Skills courses such as Project Management, Career Orientation and English Scientific Writing are integrated into the curriculum.

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The Cell Signalling in Health and Disease MRes is a research-based qualification with a taught component that is of an equivalent standard to an MSc. Read more

Programme Description

The Cell Signalling in Health and Disease MRes is a research-based qualification with a taught component that is of an equivalent standard to an MSc. The course provides a springboard into a career that involves a working knowledge of scientific research in academia and industry.

The course is designed for graduates with a BSc in the life sciences or other science disciplines, and for intercalating and fully qualified MBBS or BDS students. It can be taken either as a stand-alone qualification or as an entry route onto a PhD or MD.

The taught component of the course includes subject-specific content in the area of cell signalling in health and disease. You have the flexibility to develop your own bespoke course by selecting additional, complementary modules. You will also participate in training in general research principles, and other professional and key skills.

Your research project comprises the major element of the course. This project will involve 24 weeks of research in an area of cell signalling in health and disease under the supervision of an expert academic researcher in the field.

The course allows you to experience an internationally competitive research area, predominantly in academia but also potentially in industry.

Cell Signalling in Health and Disease MRes is closely linked to a suite of MRes courses that you may also be interested in:
•Ageing and Health MRes
•Animal Behaviour MRes
•Biotechnology and Business Enterprise MRes
•Cancer MRes
•Cardiovascular Science in Health and Disease MRes
•Diabetes MRes
•Epidemiology MRes
•Evolution and Human Behaviour MRes
•Medical Genetics MRes
•Medical Molecular Biosciences MRes
•Mitochondrial Biology and Medicine MRes
•Molecular Microbiology MRes
•Musculoskeletal Ageing (CIMA) MRes
•Neuromuscular Diseases MRes
•Neuroscience MRes
•Stem Cells and Regenerative Medicine MRes
•Systems Biology MRes
•Toxicology MRes
•Translational Medicine and Therapeutics MRes
•Transplantation MRes

Faculty of Medical Sciences Graduate School

Our Medical Sciences Graduate School is dedicated to providing you with information, support and advice throughout your research degree studies. We can help and advise you on a variety of queries relating to your studies, funding or welfare.

Our Research Student Development Programme supports and complements your research whilst developing your professional skills and confidence.

You will make an on-going assessment of your own development and training needs through personal development planning (PDP) in the ePortfolio system. Our organised external events and development programme have been mapped against the Vitae Researcher Development Framework to help you identify how best to meet your training and development needs.

Modules, Fees and How to Apply

Full information in our Prospectus online.

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Postgraduate Loans are now Open for Home/EU students. -. https://www.gov.uk/postgraduate-loan/how-to-apply. Scholarships & Discounts available. Read more

Postgraduate Loans are now Open for Home/EU students - https://www.gov.uk/postgraduate-loan/how-to-apply

Scholarships & Discounts available

This programme provides advanced contemporary training in parasitology and the study of disease vectors. The broad scope of the programme ranges from the biology, immunology, ecology and population biology of the organisms to public health, disease epidemiology and tropical health issues. In addition to providing a solid foundation in parasite and vector biology, the programme provides practical experience of essential techniques, as well as significant theoretical and practical knowledge in all important and topical areas of the field. Following the taught component, participants complete a dissertation including a period of applied research either overseas or in Liverpool.

AIMS

LSTM education courses are taught within a dynamic environment by staff working at the cutting-edge of research in tropical medicine and global health. They are designed to enable the professional development of the student, to be relevant to students from both the UK and overseas and to promote approaches to study that will enable students to continue their learning into the future. 

This course aims to: 

To equip students with the knowledge and practical skills needed to develop a career in research, training or control of parasitic and vector-borne diseases.

To provide practical experience of a range of specialised technical and analytical skills relevant to the study of parasites and disease vectors.

To enable students to conduct independent research in the laboratory and/or field.

To produce graduates who are experienced, committed, informed, proactive and effective professionals, capable of taking substantial and leading professional roles.

To facilitate high quality learning that is informed by critical analysis of current research.

To develop independent and reflective approaches to study that will enable graduates to continue to learn in the future.

CAREERS

Over many years, we have educated hundreds of Masters students, many of whom have established successful careers in research in the academic or private sectors, or who have gone on to work in development as part of government or NGO teams. Graduates of the MSc Biology & Control of Parasites and Disease Vectors typically follow careers in research (some in LSTM) or training in areas related to the control of infectious disease, in particular parasitic and vector-borne tropical diseases. Other careers paths have led to teacher training, working overseas for NGO’s, military and public health-related careers.



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This course combines theoretical and practical training in biology and control of disease vectors and the human pathogens they transmit. Read more
This course combines theoretical and practical training in biology and control of disease vectors and the human pathogens they transmit. Students will gain specialised skills in the molecular biology of infectious diseases, and will cover all aspects of major vector-borne diseases. The course also offers a thorough grounding in the systematics of medically important arthropods, processes regulating vector populations, and the biology of vector–parasite and vector–vertebrate interactions.

Graduates enter operational control programmes, applied basic research and academic fields. Students benefit from close interaction with staff who have extensive international expertise.

The James Busvine Memorial Medal and Prize, donated by Professor James Busvine in 1987, is awarded each year for outstanding performance.

- Full programme specification (pdf) (http://www.lshtm.ac.uk/edu/qualityassurance/medic_progspec.pdf)
- Intercalating this course (http://www.lshtm.ac.uk/study/intercalate)

Visit the website http://www.lshtm.ac.uk/study/masters/msbcdv.html

Objectives

By the end of this course students should be able to:

- demonstrate advanced knowledge and understanding of the biology of vectors and intermediate hosts of human pathogens together with methods for their control

- describe the biology, pathogenesis and diagnosis of parasitic infections in humans and relate these to human health and disease control strategies

- demonstrate a range of specialised technical and analytical skills relevant to vectors and vector-borne diseases

- design and carry out a research project on biology or control of disease vectors, analyse and interpret the results and prepare a report including a critical literature review

- design, undertake and evaluate vector control interventions, and show written and verbal competence in communicating scientific information

Structure

Term 1:
There is a one-week orientation period that includes an introduction to studying at the School, sessions on key computing and study skills and an introduction to major groups of pathogens, followed by three compulsory core modules:

- Parasitology & Entomology
- Analysis & Design of Research Studies
- Critical Skills for Tropical Medicine

Sessions on basic computing, molecular biology and statistics are run throughout the term for all students.

Terms 2 and 3:
Students take a total of five modules, one from each timetable slot (Slot 1, Slot 2 etc.). Some modules can be taken only after consultation with the Course Director.

*Recommended modules

- Slot 1:
Epidemiology & Control of Malaria*
Designing Disease Control Programmes in Developing Countries
Molecular Biology & Recombinant Techniques

- Slot 2:
Advanced Diagnostic Parasitology*
Design & Analysis of Epidemiological Studies
Statistical Methods in Epidemiology

- Slot 3:
Vector Sampling, Identification & Incrimination (compulsory)

- Slot 4:
Vector Biology & Vector Parasite Interactions*
Epidemiology & Control of Communicable Diseases
Molecular Biology Research Progress & Applications
Population Dynamics & Projections

- Slot 5:
Integrated Vector Management (compulsory)

Further details for the course modules - http://www.lshtm.ac.uk/study/currentstudents/studentinformation/msc_module_handbook/section2_coursedescriptions/tbcd.html

Residential Field Trip

There is a compulsory one week field course, after the Term 3 examinations, on vector and parasite sampling and identification methods. The cost of £630 is included in the field trip fee.

Project Report

During the summer months (July - August), students complete a field or laboratory research project on an appropriate entomological topic, for submission by early September.

Titles of some of the recent summer projects completed by students on this MSc

Due to our collaborative networking, students are given the opportunity to conduct research projects overseas. This unique experience provides students with skills that are highly desirable to potential employers. The majority of students who undertake projects abroad receive financial support for flights from the School's trust funds set up for this purpose.

Find out how to apply here - http://www.lshtm.ac.uk/study/masters/msbcdv.html#sixth

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This course blends theory and practice to help you develop the skills required for a career in molecular and cellular biology. Our teaching focuses on integrated mammalian biology and animal models of human disease, drawing on our pioneering biomedical research. Read more

About the course

This course blends theory and practice to help you develop the skills required for a career in molecular and cellular biology. Our teaching focuses on integrated mammalian biology and animal models of human disease, drawing on our pioneering biomedical research.

Where your masters can take you

Graduates with skills in stem cell and regenerative medicine are in demand. Your degree will prepare you for a career in research in academia or industry, or in a clinical-related field. Our graduates are working all over the world – from the UK to China, India and the USA – and over half go on to doctoral study.

Learn from the experts

The 2014 Research Excellence Framework (REF) rates us No 1 in the UK for research in this field. Our international reputation attracts highly motivated staff and students. Sheffield is a vibrant place to take a masters based on pioneering research.

Regular seminars from distinguished international experts help you to connect your studies to the latest developments. We’re also part of collaborative research groups for developmental biology, cell biology, physiology, pharmacology, neuroscience, models of human disease, stem cell science and regenerative medicine.

Our three research centres focus on translating laboratory research to the clinical environment: Bateson Centre, the Centre for Stem Cell Biology, and the Centre for Membrane Interactions and Dynamics.

Leaders in our field

We have a long track record of groundbreaking discoveries. These include breakthroughs in human stem cells for hearing repair, and the generation of animal models for Parkinson’s disease, schizophrenia, muscular dystrophies and their use for therapeutic studies.

Labs and equipment

We have purpose-built facilities for drosophila, zebrafish, chick and mouse genetics and for molecular physiology. Other facilities provide all the tools you’ll need to examine and analyse a range of cellular structures. We have an electron and a light microscopy centre, a PCR robotics facility, a flow cytometry unit and an RNAi screening facility.

Teaching and assessment

There are lectures, practical classes, tutorials and seminars. In small group teaching classes you’ll discuss, debate and present on scientific and ethical topics. Laboratory placements within the department provide you with one-to-one attention, training and support to do your individual research project. Assessment is by formal examinations, coursework assignments, debates, poster presentations and a dissertation.

Our teaching covers ethics, practical scientific skills and an overview of the current literature. You’ll also develop useful career skills such as presentation, communication and time management.

Core modules

Literature Review; Practical Research Project; Analysis of Current Science; Ethics and Public Understanding.

Examples of optional modules

Integrated Mammalian Biology; Practical Cell Biology; Practical Developmental Genetics; Cancer Biology; Modelling Human Diseases; Epithelia in Health and Disease.

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Public health and communicable disease control focuses on tropical population health needs, particularly the spread of infectious disease. Read more

What is public health and communicable disease control?

Public health and communicable disease control focuses on tropical population health needs, particularly the spread of infectious disease.

Who is this course for?

This course is designed for health professionals with a suitable undergraduate degree or recognised professional qualification in a relevant discipline. It provides the skills and knowledge to use infection controls within hospitals and health care settings, particularly in rural and remote areas.

Course learning outcomes

JCU graduates are committed to lifelong learning, intellectual development, and to the display of exemplary personal, professional and ethical standards. They have a sense of their place in the tropics and are charged with professional, community, and environmental responsibility. JCU graduates appreciate the need to embrace and be acquainted with the Aboriginal and Torres Strait Islander Peoples of Australia. They are committed to reconciliation, diversity and sustainability. They exhibit a willingness to lead and to contribute to the intellectual, environmental, cultural, economic and social challenges of regional, national, and international communities of the tropics.
Upon successful completion of the Master of Public Health, graduates will be able to:
*Devise appropriate strategies to detect, prevent and control communicable and non-communicable diseases ensuring safe and healthy environments for tropical, rural, remote and Indigenous communities
*Critically assess, analyse and communicate public health information relevant to tropical, rural, remote and Indigenous communities
*Communicate theoretical propositions, methodologies, conclusions and professional decisions through advanced literacy and numeracy skills to specialist and non-specialist audiences
*Critically reflect upon the socio-ecological nature of health promotion and its application in optimising the health and wellbeing of tropical, rural, remote and Indigenous communities
*Critically reflect upon and engage in professional public health practice based on ethical decision-making and an evidence based approach, including consideration of recent developments in the field
*Apply advanced human, project and organisational management skills within a public health and policy context to effect efficient and equitable gains in public health
*Apply knowledge of research principles and methods to plan and ethically execute a substantial research-based project, capstone experience and/or piece of scholarship.

Graduates with a MPH Health Promotion major will also be able to:
*Integrate and apply an advanced body of theoretical and technical knowledge in the discipline of public health, with depth in population health assessment and health promotion planning, implementation and evaluation.

Graduates with a MPH Biosecurity and Disaster Preparedness major will also be able to:
*Integrate and apply an advanced body of theoretical and technical knowledge in the discipline of public health, with depth in disaster health and humanitarian response

Graduates with an MPH Aeromedical Retrieval major will also be able to:
*Integrate and apply an advanced body of theoretical and technical knowledge in the discipline of public health, with depth in the epidemiology, history, physiological effects, and management of patients undergoing aeromedical retrieval in a range of aircraft and settings including the impact of ethical, cultural, legal and financial issues

Graduate with a MPH Communicable Diseases major will also be able to:
*Integrate and apply an advanced body of theoretical and technical knowledge in the discipline of public health, with depth in principles of communicable disease control.

Award title

MASTER OF PUBLIC HEALTH (MPH)

Entry requirements (Additional)

English band level 3a - the minimum English Language test scores you need are:
*IELTS – 7.0 (no component lower than 6.5), OR
*TOEFL – 577 (plus minimum Test of Written English score of 5.5), OR
*TOEFL (internet based) – 100 (minimum writing score of 23), OR
*Pearson (PTE Academic) - 72

If you meet the academic requirements for a course, but not the minimum English requirements, you will be given the opportunity to take an English program to improve your skills in addition to an offer to study a degree at JCU. The JCU degree offer will be conditional upon the student gaining a certain grade in their English program. This combination of courses is called a packaged offer.
JCU’s English language provider is Union Institute of Languages (UIL). UIL have teaching centres on both the Townsville and Cairns campuses.

Minimum English language proficiency requirements

Applicants of non-English speaking backgrounds must meet the English language proficiency requirements of Band 3a – Schedule II of the JCU Admissions Policy.

Why JCU?

James Cook University provides several programs unique to Australia. James Cook University has:
*The Anton Breinl Centre for Public Health and Tropical Medicine, which is one of the leading tropical research facilities in the world
*teaching staff awarded the Australian Learning Teaching Councils’ National Citation for Outstanding Contribution to Student Learning
*cutting-edge teaching laboratories and research facilities.

Application deadlines

*1st February for commencement in semester one (February)
*1st July for commencement in semester two (mid-year/July)

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The MRes in Biomedical Research - Molecular Basis of Human Disease provides training and teaching in multidisciplinary approach to understand disease mechanisms. Read more
The MRes in Biomedical Research - Molecular Basis of Human Disease provides training and teaching in multidisciplinary approach to understand disease mechanisms. The emphasis of the MRes is on a broad range of training from structural and chemical biology to clinical applications in order to gain knowledge across the biological scales from atoms, molecules to whole cell/organisms on pressing human diseases such as cancer, cardiovascular and pulmonary diseases, metabolic and cellular disease as well as pathogen infection and resistance.

Like the other MRes streams, this course exposes students to the latest developments in the field through two research projects that are complementary in training, with one focusing on molecular mechanism while the other one on disease pathways and/or clinical applications. This course is further supplemented by lectures, tutorials and seminars.

Students will gain experience in applying technologically advanced approaches to biomedical questions. Individuals who successfully complete the course will have developed the ability to:

-Perform novel laboratory based research and exercise critical scientific thought in the interpretation of results.
-Undertake two research projects in line with the multidisciplinary culture of the Section and Division.
-Demonstrate practical and intellectual dexterity in the research project elements.
-Develop an appreciation of cutting edge technologies addressing molecular mechanisms and current understanding of key diseases pathways and mechanisms.
-Be able to interpret and present scientific data
-Be able to interrogate relevant scientific literature and develop research plans.
-Be able to write a grant application, through the taught grant-writing exercise common to all MRes streams.
-Be able to write and defend research reports through writing, poster presentations and seminars.
-Exercise a range of transferable skills by taking a minimum number of short courses taught through the Graduate School.

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