Masters Degrees (Clinical Genetics)

The increasing impact of genetics in healthcare and the development of newer sophisticated technologies requires close collaboration between research scientists, clinical laboratory scientists and clinicians to deliver a high quality service to patients. The Clinical Genetics MSc has a specific focus on delivery of the clinical service to patients including risk analysis and application of modern genetic and genomic technologies in medical genetics research and in diagnostics and population screening.

● This is a fully up-to-date Clinical Genetics degree delivered by dedicated, multi-award-winning teaching and clinical staff of the University, with considerable input from hospital-based Regional Genetics Service clinicians and clinical scientists.
● The full spectrum of genetic services is represented, from patient and family counselling to diagnostic testing of individuals and screening of entire populations for genetic conditions: eg the NHS prenatal and newborn screening programmes.
● The Clinical Genetics MSc Teaching Staff won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering). These awards recognise and reward excellence and good practice in postgraduate education.
● The close collaboration between university and hospital staff ensures that the Clinical Genetics MSc provides a completely up-to-date representation of the practice of medical genetics and you will have the opportunity to observe during clinics at the new Queen Elizabeth University Hospital laboratory medicine building.
● The Clinical Genetics degree explores the effects of mutations and variants as well as the theoretically basis of current techniques used in NHS genetics laboratory diagnostics and recent developments in diagnostics (including microarray analysis and the use of massively parallel [“next-generation”] sequencing).
● New developments in genetics are incorporated into the lectures and interactive teaching sessions very soon after they are presented at international meetings or published, and you will gain hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenesis of DNA sequence variants.
● You will develop your skills in problem solving, evaluation and interpretation of genetic data, literature searches, scientific writing, oral presentations, poster presentations and team working.
● This MSc programme will lay the academic foundations on which some students with prior MBChB or MBBS may build in pursuing careers in Clinical Genetics.
● The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.
● For doctors: The Joint Royal Colleges of Physicians’ Training Board (JRCPTB) in the UK recognises the MSc in Clinical Genetics (which was established in 1984) as counting for six months of the higher specialist training in Clinical Genetics.

Programme Structure

Genetic Disease and Clinical Practice

This course is designed in collaboration with the West of Scotland Regional Genetics Service to give students a working knowledge of the principles and practice of Clinical Genetics and Genomics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease. The link from genotype to phenotype, will be explored, with consideration of how this knowledge might contribute to new therapeutic approaches.

Distress or Disorder: Reactions to a medical diagnosis

This course outlines the process of psychosocial adjustment to a diagnosis or test result allowing participants to establish if and when a distress reaction develops into an adjustment disorder. The implications of diagnosis are explored and evidence considered allowing informed decisions about appropriate referrals to other agencies.

Patient Empowerment: Supporting decisions relating to new diagnoses

This course reflects on evidence and experience to explore the psychological and social impact of a diagnosis, or illness, and provides strategies to support resilience and coping in patients. Factors related to lived experience, personal beliefs and values, culture, adjustment processes, decision-making, misconceptions, secrecy and guilt are considered to equip participants in the promotion of patient-centred care.

Effective listening and communication skills

With a focus on experiential learning and student led study, this course outlines the role of counselling skills to facilitate adjustment and to allow an individual to come to terms with change in a safe way to minimise impact. The focus will be on the theory supporting counselling, developing key listening and communication skills and on establishing reflective practice.

Case Investigations in Medical Genetics and Genomics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Clinical Genomics

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussion the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Disease Screening in Populations

This course will cover the rationale for, and requirements of, population screening programmes to detect individuals at high risk of particular conditions, who can then be offered diagnostic investigations. Students will work in groups to investigate and report on, a screening programme of their choice from any country.

Dissertation

The course will provide students with the opportunity to carry out an independent investigative project in the field of Medical Genetics and Genomics.

Teaching and Learning Methods

A variety of methods are used, including problem-based learning, case-based learning, lectures and tutorials. These are supplemented by a wide range of course-specific electronic resources for additional learning and self-assessment. As a result, you will develop a wide range of skills relevant to careers in clinical genetics. These skills include team-working and data interpretation. You will use the primary scientific literature as an information resource, although textbooks such as our own Essential Medical Genetics will also be useful. You will have the options of: attending genetic counselling clinics and gaining hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenicity of DNA sequence variants.

Visit the website for more information http://www.gla.ac.uk/postgraduate/taught/clinicalgenetics/#/programmestructure

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The Genetics of Human Disease MSc aims to provide students with an in-depth knowledge of molecular genetics, quantitative and statistical genetics and human disease and how this can be applied to improve healthcare through the development and application of diagnostic tests and therapeutic agents.

Degree Information

The programme provides a thorough grounding in modern approaches to the understanding of the genetics of disease alongside the cutting-edge research methods and techniques used to advance our understanding of development of disease. Core modules provide a broad coverage of the genetics of disease, research skills and social aspects, whilst specialised streams in Inherited Diseases, Pharmacogenetics and Computational Genomics, in which students can qualify, and the research project allow more in-depth analysis in areas of genetics.

Students undertake modules to the value of 180 credits.

The programme consists of four core modules (60 credits) and two specialist modules (30 credits) and a research project culminating in a dissertation (90 credits).

A Postgraduate Diploma consisting of six modules (four core modules in term one and two modules within the selected stream in term two) is offered, full-time nine months.

A Postgraduate Certificate consisting of four core modules in term one (60 credits) is offered, full-time three months.

Core Modules
- Advanced Human Genetics: Research Principles
- Human Genetics in Context
- Core Skills
- Basic Statistics for Medical Sciences

Specialist modules
In term two you will take specialist modules depending on the specialist stream you select: Inherited Disease (A); Pharmacogenetics (B); Computational Genomics (C).
- Applications in Human Genetics (A)
- Either Genetics of Cardiovascular Disease or Genetics of Neurological Disease (A)
- Clinical Applications of Pharmacogenetic Tests (B)
- Anti-Cancer Personalised Medicine or Pharmacogenomics, Adverse Drug Reactions and Biomarkers (B)
- Applications in Human Genetics (C)
- Statistics for Interpreting Genetic Data (C)

Dissertation/report
Students undertake an original research project investigating topical questions in genetics and genetics of human disease which culminates in a dissertation of 12,000 to 14,000 words and an oral presentation.

Teaching and learning
Students develop their knowledge and understanding of genetics of human diseases through a combination of lectures, seminars, tutorials, presentations and journal clubs. Taught modules are assessed by unseen written examination and/or, written reports, oral presentations and coursework. The research project is assessed by the dissertation and oral presentation.

Careers

Advanced training in genetic techniques including bioinformatic and statistical approaches positions graduates well for PhD studentships in laboratories using genetic techniques to examine diseases such as heart disease, cancer and neurological disorders. Another large group will seek research jobs in the pharmaceutical industry, or jobs related to genetics in healthcare organisations.

Employability
The MSc in Genetics of Human Disease facilitates acquisition of knowledge and skills relevant to a career in research in many different biomedical disciplines. About half of our graduates enter a research career by undertaking and completing PhDs and working as research associates/scientists in academia. Some of our graduates go on to jobs in the pharmaceutical industry, while others enter careers with clinical genetic diagnosis services, particularly in molecular genetics, in healthcare organisations and hospitals around the world. Those graduates with a prior medical training often utilise their new skills as clinical geneticists.

Why study this degree at UCL?

UCL is in a unique position to offer both the basic science and application of modern genetics to improve human health. The programme is a cross-faculty initiative with teaching from across the School of Life and Medical Sciences (SLMS) at UCL.

Students will be based at the UCL Genetics Institute (UGI), a world-leading centre which develops and applies biostatistical and bioinformatic approaches to human and population genetics. Opportunities to conduct laboratory or computational-based research projects are available in the laboratories of world-leading geneticists affiliated to the UGI.

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The increasing impact of genetics in healthcare and the development of newer sophisticated technologies requires contributions from research scientists, clinical laboratory scientists and clinicians to investigate the causes of, and therefore permit optimal management for, diseases for which alterations in the genome, either at the DNA sequence level or epigenetic level, play a significant role. Collaboration between staff from the University of Glasgow and the NHS West of Scotland Genetics Service enables the MSc in Medical Genetics and Genomics to provide a state-of-the-art view of the application of modern genetic and genomic technologies in medical genetics research and diagnostics, and in delivery of a high quality genetics service to patients, as well as in design of targeted therapies.

Why this programme

◾This is a fully up-to-date Medical Genetics degree delivered by dedicated, multi-award-winning teaching and clinical staff of the University, with considerable input from hospital-based Regional Genetics Service clinicians and clinical scientists.
◾The full spectrum of genetic services is represented, from patient and family counselling to diagnostic testing of individuals and screening of entire populations for genetic conditions: eg the NHS prenatal and newborn screening programmes.
◾The MSc Medical Genetics Course is based on the south side of the River Clyde in the brand new (2015) purpose built Teaching & Learning Centre, at the Queen Elizabeth University Hospitals (we are located 4 miles from the main University Campus). The Centre also houses state of the art educational resources, including a purpose built teaching laboratory, computing facilities and a well equipped library. The West of Scotland Genetic Services are also based here at the Queen Elizabeth Campus allowing students to learn directly from NHS staff about the latest developments to this service.
◾The Medical Genetics MSc Teaching Staff have won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering). These awards recognise and reward excellence and good practice in postgraduate education.
◾The close collaboration between university and hospital staff ensures that the Medical Genetics MSc provides a completely up-to-date representation of the practice of medical genetics and you will have the opportunity to observe during clinics and visit the diagnostic laboratories at the new Southern General Hospital laboratory medicine building.
◾The Medical Genetics degree explores the effects of mutations and variants as well as the current techniques used in NHS genetics laboratory diagnostics and recent developments in diagnostics (including microarray analysis and the use of massively parallel [“next-generation”] sequencing).
◾New developments in medical genetics are incorporated into the lectures and interactive teaching sessions very soon after they are presented at international meetings or published, and you will gain hands-on experience and guidance in using software and online resources for genetic diagnosis and for the evaluation of pathogenesis of DNA sequence variants.
◾You will develop your skills in problem solving, experimental design, evaluation and interpretation of experimental data, literature searches, scientific writing, oral presentations, poster presentations and team working.
◾This MSc programme will lay the academic foundations on which some students may build in pursuing research at PhD level in genetics or related areas of biomedical science or by moving into related careers in diagnostic services.
◾The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.
◾For doctors: The Joint Royal Colleges of Physicians’ Training Board (JRCPTB) in the UK recognises the MSc in Medical Genetics and Genomics (which was established in 1984) as counting for six months of the higher specialist training in Clinical Genetics.
◾The Medical Council of Hong Kong recognises the MSc in Medical Genetics and Genomics from University of Glasgow in it's list of Quotable Qualifications.

Programme structure

Genetic Disease: from the Laboratory to the Clinic

This course is designed in collaboration with the West of Scotland Regional Genetics Service to give students a working knowledge of the principles and practice of Medical Genetics and Genomics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease. The link from genotype to phenotype, will be explored, with consideration of how this knowledge might contribute to new therapeutic approaches.

Case Investigations in Medical Genetics and Genomics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Clinical Genomics

Students will take this course OR Omic Technologies for Biomedical Sciences OR Frontiers in Cancer Science.

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussion the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Omic technologies for the Biomedical Sciences: from Genomics to Metabolomics

Students will take this course OR Clinical Genomics OR Frontiers in Cancer Science.

Visit the website for further information

Career prospects

Research: About half of our graduates enter a research career and most of these graduates undertake and complete PhDs; the MSc in Medical Genetics and Genomics facilitates acquisition of skills relevant to a career in research in many different bio-molecular disciplines.

Diagnostics: Some of our graduates enter careers with clinical genetic diagnostic services, particularly in molecular genetics and cytogenetics.

Clinical genetics: Those of our graduates with a prior medical / nursing training often utilise their new skills in careers as clinical geneticists or genetic counsellors.

Other: Although the focus of teaching is on using the available technologies for the purpose of genetic diagnostics, many of these technologies are used in diverse areas of biomedical science research and in forensic DNA analysis. Some of our numerous graduates, who are now employed in many countries around the world, have entered careers in industry, scientific publishing, education and medicine.

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The College of Liberal Arts and Sciences is a thriving center of intellectual excellence that encompasses 14 academic departments and 80 degree programs. Its more than 2,500 students are engaged in a wide variety of challenging courses and hands-on learning experiences that extend across all areas of the humanities and sciences – from the great philosophers and classic literature to the world economy and environmental sustainability.

At the core of each department are faculty members who have garnered national acclaim for their best-selling books, ground-breaking research and creative endeavors. Together, students and their professors explore globally significant subjects and work towards the goal of improving every aspect of the way in which human beings live. To learn more about a specific area of study, click on the left-hand navigation bar for a full listing of academic departments.

Genetic Counseling

As genetic testing becomes more available and patients gain unprecedented access to information about birth defects and the likelihood of diseases and medical conditions, the need for professionals who can help them understand and act on genetic test results is increasing rapidly.

The LIU Post master's program in Genetic Counseling is the first of its kind on Long Island and only the third in New York State. It is one of just 32 genetic counseling master’s degree programs nationwide accredited by the Accreditation Council for Genetic Counseling.

The program is committed to developing a new generation of genetic counselors with the knowledge and skill to help patients make the best decisions. With a diverse, interdisciplinary academic and clinical faculty, the two-year program is geared toward students who desire a rigorous and comprehensive training in the field of clinical genetics. The program emphasizes the scientific, clinical and psychosocial aspects of genetic counseling. Skills learned through classroom-based didactics pave the way for students to enter their clinical rotations for “real-world” training. Additionally, a number of supplementary activities ensure that students will be exposed to non-traditional careers in genetic counseling along with traditional, clinic-based careers.

M.S. Genetic Counseling

The LIU Post M.S. in Genetic Counseling is the first of its kind on Long Island and only the third in New York State. It is one of just 31 genetic counseling master’s degree programs nationwide accredited by the Accreditation Council for Genetic Counseling.

The mission of the Genetic Counseling program is to develop genetic counselors that have the knowledge, skill and experience to succeed in all areas of the field by providing comprehensive training emphasizing scientific, clinical and psychosocial aspects of genetic counseling.

As genetic testing becomes more available and patients gain unprecedented access to information about birth defects and the likelihood of diseases and medical conditions, the need for professionals who can help them understand and act on genetic test results is increasing rapidly.

The 46-credit Master of Science program in Genetic Counseling at LIU Post is committed to developing a new generation of genetic counselors with the knowledge and skill to help patients make the best decisions. With a diverse, interdisciplinary academic and clinical faculty, the two-year program is geared toward students who desire a rigorous and comprehensive training in the field of clinical genetics. The program emphasizes the scientific, clinical and psychosocial aspects of genetic counseling. Skills learned through classroom-based didactics pave the way for students to enter their clinical rotations for “real-world” training. Additionally, both classroom work and numerous supplementary activities ensure that students will be exposed to expanded roles in genetic counseling in addition to traditional, clinic-based careers.

The M.S. in Genetic Counseling at LIU Post is dedicated to training a diverse group of students to become leaders in the field of clinical genetics. We believe in embracing a supportive and collaborative atmosphere between our students and faculty. We encourage you to learn more about this program, and look forward to reading your application.

Students conduct important, life saving research in the Joseph, Tita, and Don Monti Genetics Lab.

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Translating fundamental biomedical discoveries into applied clinical practice and public health issues

Clinical Biology is the only specialisation in the Netherlands that combines fundamental human biology with clinical studies. It provides you with an extensive biological knowledge, and experience in working with animal and patient samples. In this way you’ll be trained to bridge the gap between early biomedical research results and clinical practice.

This wouldn’t be possible within the walls of the Faculty of Science. That’s why there’s an extensive collaboration between the Faculty of Science and the Radboud university medical center in the field of Clinical Biology. You’ll get the best of both worlds: a thorough background in for example molecular oncology, human genetics, physiology and metabolism as well as a clinical view on diseases. This is an excellent background for a medical researcher or a job at the interface of science and society, such as a consultant, policy officer or communications advisor in the area of food or health.

See the website http://www.ru.nl/masters/clinicalbiology

Why study Clinical Biology at Radboud University?

- It is the only programme in the Netherlands that bridges the gap between fundamental biomedical research and clinical treatments.
- You’ll get the opportunity to work together with researchers from the Radboud university medical center.
- Radboud biologists and clinicians stand out in the fields of animal and human physiology, human genetics and disease, and molecular and cellular clinical studies.
- Clinical Biology offers internships at multiple related research institutes, such as the Radboud Institute for Molecular Life Sciences (RIMLS), the Radboud Institute for Health Sciences (RIHS) and the Donders Institute for Brain, Cognition and Behaviour (DI).
- There are various opportunities to do an internship abroad thanks to our wide network of cooperating research groups.

Career prospects

After graduation, our students quickly take up positions as researchers in government departments, research organisations and medical or pharmaceutical companies. However, many of our graduates also apply their academic background to societal issues, for example as a communications or policy officer. In general, clinical biologists end up as a:
- Researcher in a hospital or a university
- Researcher in a company, either a large or a start-up company
- Supervisor of clinical trials
- Consultant in the area of health or food
- Policy officer in the area of health or food
- Communications officer at a hospital or a governmental organisation, like RIVM
- Teacher in biology or medical biology

PhD positions at Radboud University
Each year, Radboudumc offers PhD positions in this field of research. Of course, many graduates also apply for a PhD position at related departments in the Netherlands, or abroad.

Our approach to this field

- From human biology to clinical treatment
Clinical Biology at Radboud University connects fundamental biological research to clinical treatments. The courses will provide you with a solid background in human physiology and molecular biology, which you’ll apply in developing clinically-oriented research questions. As there’s an extensive collaboration between the Faculty of Science and the Radboud university medical center, you’ll become familiar with both perspectives.

- Biomaterials
In your internships you’ll work with biomaterials, such as patient and animal samples. This means you’ll apply your biological knowledge to real-life situations. Clinical biologists do not work with patients or clinical treatments directly.

- Three focus areas
This Master’s specialisation focuses on three main topics:

- Molecular Mechanisms of Novel Therapeutics
Which molecular mechanisms lead to cancer? And how can these be translated into clinical practice? These are key questions in the specialisation in Clinical Biology. For example, we’ll dive into the functioning of epigenetics (heritable modifications of chromosomes without altering the nucleotide sequence), transcription factors, tumour suppressors and immunotherapy.

- Human Genetics and Physiology
This part is about how new developments and discoveries in genetic and molecular fields can help individual patients to improve functionality, independence and quality of life. You’ll study genetic pathways and the functionality of individual organs, organ systems, regulatory mechanisms, and individuals as a whole, in an integrative way.

- Metabolism, Transport and Mobility
The energy balance in our body is one of the most important factors in health and disease. We’ll teach you how energy and metabolites are integrated into the larger cellular networks for metabolism, transport and motility.

See the website http://www.ru.nl/masters/clinicalbiology

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The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Research areas include: genetic medicine, developmental genetics, neuromuscular and neurological genetics, mitochondrial genetics and cardiovascular genetics.

As a research postgraduate in the Institute of Genetic Medicine you will be a member of our thriving research community. The Institute is located in Newcastle’s Life Science Centre. You will work alongside a number of research, clinical and educational organisations, including the Northern Genetics Service.

We offer supervision for MPhil in the following research areas:

Cancer genetics and genome instability

Our research includes:
-A major clinical trial for chemoprevention of colon cancer
-Genetic analyses of neuroblastoma susceptibility
-Research into Wilms Tumour (a childhood kidney cancer)
-Studies on cell cycle regulation and genome instability

Cardiovascular genetics and development

We use techniques of high-throughput genetic analyses to identify mechanisms where genetic variability between individuals contributes to the risk of developing cardiovascular disease. We also use mouse, zebrafish and stem cell models to understand the ways in which particular gene families' genetic and environmental factors are involved in the normal and abnormal development of the heart and blood vessels.

Complex disease and quantitative genetics

We work on large-scale studies into the genetic basis of common diseases with complex genetic causes, for example autoimmune disease, complex cardiovascular traits and renal disorders. We are also developing novel statistical methods and tools for analysing this genetic data.

Developmental genetics

We study genes known (or suspected to be) involved in malformations found in newborn babies. These include genes involved in normal and abnormal development of the face, brain, heart, muscle and kidney system. Our research includes the use of knockout mice and zebrafish as laboratory models.

Gene expression and regulation in normal development and disease

We research how gene expression is controlled during development and misregulated in diseases, including the roles of transcription factors, RNA binding proteins and the signalling pathways that control these. We conduct studies of early human brain development, including gene expression analysis, primary cell culture models, and 3D visualisation and modelling.

Genetics of neurological disorders

Our research includes:
-The identification of genes that in isolation can cause neurological disorders
-Molecular mechanisms and treatment of neurometabolic disease
-Complex genetics of common neurological disorders including Parkinson's disease and Alzheimer's disease
-The genetics of epilepsy

Kidney genetics and development

Kidney research focuses on:
-Atypical haemolytic uraemic syndrome (aHUS)
-Vesicoureteric reflux (VUR)
-Cystic renal disease
-Nephrolithiasis to study renal genetics

The discovery that aHUS is a disease of complement dysregulation has led to a specific interest in complement genetics.

Mitochondrial disease

Our research includes:
-Investigation of the role of mitochondria in human disease
-Nuclear-mitochondrial interactions in disease
-The inheritance of mitochondrial DNA heteroplasmy
-Mitochondrial function in stem cells

Neuromuscular genetics

The Neuromuscular Research Group has a series of basic research programmes looking at the function of novel muscle proteins and their roles in pathogenesis. Recently developed translational research programmes are seeking therapeutic targets for various muscle diseases.

Stem cell biology

We research human embryonic stem (ES) cells, germline stem cells and somatic stem cells. ES cell research is aimed at understanding stem cell pluripotency, self-renewal, survival and epigenetic control of differentiation and development. This includes the functional analysis of genes involved in germline stem cell proliferation and differentiation. Somatic stem cell projects include programmes on umbilical cord blood stem cells, haematopoietic progenitors, and limbal stem cells.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.

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The UCL Division of Psychiatry is pleased to offer this programme focused on clinical practice in mental health and its evidence base. The Clinical Mental Health Sciences MSc integrates biological, psychological and social perspectives on mental health and caters both for psychology graduates and for clinicians wishing to undertake a broad-based, rigorous and flexible higher degree.

Degree information

Students will develop an in-depth understanding of current evidence regarding mental health problems and the interventions provided to address them, as well as enhancing their research skills. A wide range of options from across the School of Life and Medical Sciences at UCL allows students to tailor a programme that fully fits their needs.

Students undertake modules to the value of 180 credits.

The programme consists of 1–2 core double modules (30–60 credits), 4–6 optional modules (60–90 credits) and a dissertation/report (60 credits). A diploma may be awarded to students who complete the equivalent of 8 taught single modules, amounting to 120 credits. A certificate may be awarded to students who complete the equivalent of 4 taught single modules, amounting to 60 credits.

Core modules
-Core Principles of Mental Health Research (double module)
-Clinical Mental Health (double module – compulsory only for those who do not have at least six months’ full-time experience, or the equivalent, of working in mental health settings).

Optional modules - students who take the Clinical Mental Health module will choose at least one option (15 credits) from the following:
-Current Research in Depression and Anxiety
-Current Research in Dementia
-Current Research in Learning Disability
-Current Research in Psychosis
-Mental Health Services – Policy, Design and Evaluation
-Culture in the Clinic
-Advanced Treatment and Management of Dementia (only to be taken if Current Research in Dementia has already been taken)

Please note: Students who do not take the Clinical Mental Health module will select at least three modules (45 credits) from the above list. Any UCL modules approved by the Programme Director can be selected to make up the remaining credit(s). Note that due to timetable clashes only one Institute of Child Health module may be taken by each student. Approved options, from across UCL, include:
-Ethnicity, Migration and Health (Department of Epidemiological and Social Methods in Public Health)
-Social Determinants of Health (Department of Epidemiology and Public Health)
-Higher Functions of the Brain (Institute of Neurology)
-Neurodevelopmental Disorders in Child Mental Health (UCL Institute of Child Health)
-Interventions in Child and Adolescent Mental Health – Psychological (UCL Institute of Child Health)
-Quality Improvements in Health (UCL CHIME)
-Neuroimaging: Introductory Science and Methods (Institute of Neurology)
-Neuroimaging: Imaging Modalities (Institute of Neurology)
-Treatment in Child and Adolescent Mental Health - Pharmacological (UCL Institute of Child Health)

(Note that due to timetable clashes only one UCL Institute of Child Health module may be taken by each student)

NB: due to timetable clashes only one UCL Institute of Child Health module may be taken by each student.

Research project/report
All students undertake a final project. This may be a research project, to be reported as a paper of 6,000-8,000 words ready for submission to a specified journal, a blog of 1,000 words and a 20-minute talk, or a clinical project of 10,000 words reporting on a clinical topic or service evaluation.

Teaching and learning
The programme is delivered through lectures, seminars and workshops, with considerable use of supporting online learning. Assessment methods include one unseen examination, coursework including designing questionnaires and protocols and analysing data, giving talks and presenting posters, and a final report in the format of a journal paper or brief for clinicians or service planners.

Placement
The programme team support students in obtaining volunteer placements in relevant mental health care and research settings, but this is not a formal part of the course and is entirely optional.

Careers

For non-clinicians, the programme will be an excellent grounding for clinical training, such as in clinical psychology, or for embarking on a research career in mental health. Many graduates go on to research assistant, clinical support worker or assistant psychologist posts as a first destination. For clinicians, this is a great opportunity to gain a higher qualification through a programme based in a leading university department which can be closely tailored to your interests across clinical, research and management fields.

Employability
Students will be taught by leading experts in their fields, will gain a strong clinical understanding of mental health, and will be able to develop their skills in research, service design and evaluation, and writing and presenting. Previous Division of Psychiatry Master’s graduates have been enthusiastic about their career enhancement, both through their programme and the connections they have made through it. A large proportion of our first cohort of graduates have gone on to paid employment in relevant areas of mental health, especially research assistant, clinical support worker, psychological wellbeing practitioner and assistant psychologist posts. Others have embarked on PhD studies.

Why study this degree at UCL?

UCL has a cluster of international experts in mental health, including in genetics, epidemiology, and applied clinical research, and most are also clinicians. We are able to offer a broad programme encompassing both cutting-edge research and a clinical perspective.

The programme is strongly focused on student participation, with much use of small-group learning, and the environment in the Division of Psychiatry is stimulating, friendly and supportive.

A wide range of options at UCL allows programmes to be tailored to students’ needs and interests in clinical, research and management domains.

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The aim of the Clinical Neuroscience MSc course is to give you a unique understanding of the principles underlying the clinical presentation and investigation of diseases affecting the brain. We place particular emphasis on the translation from basic science to clinical practice. Our course is suitable for students interested in neuroscience and its applications to neurological or psychiatric diseases.

Key benefits

- Provides a deep and detailed understanding of brain diseases.
- Emphasis on the translation from basic science to clinical practice.
- Designed to introduce the basic scientific concepts which underlie clinical symptoms, signs and practice.

Visit the website: http://www.kcl.ac.uk/study/postgraduate/taught-courses/clinical-neuroscience-msc.aspx

- Description -

Our Clinical Neuroscience course enables trainees in neurology, psychiatry and related health-care disciplines to study the anatomical, physiological and pathological basis of symptoms and signs of brain disorders. It will provide you with in-depth knowledge and skills related to specialist clinical practice and will systematically integrate advances in genetics, molecular neuroscience, electrophysiology and neuroimaging into clinical practice. You will have the opportunity to work independently within a multidisciplinary environment and at an advanced level to develop and sustain evidence-based practice, appraise and conduct clinical research and audit.

- Purpose -

Provides students with a clinical background or interest, with a unique understanding of the underlying principles of neurological symptoms, signs, investigations and diseases. Particular emphasis is given to translation from basic science to clinical practice. Suitable for degree holders in medicine, nursing and other professions allied to medicine. Will equip graduates with the tools for the next stage of their career.

- Format and assessment -

Units are taught twice a week. Units consist of formal lectures and clinical case presentations, followed by a master class in which the case is discussed in depth. There is a written assessment and presentation of essay for each module, and an end-of-term programme dissertation.

A full list of required and optional modules are available on our website http://www.kcl.ac.uk/study/postgraduate/taught-courses/clinical-neuroscience-msc.aspx

Career prospects

Clinical and non-clinical academic careers in neurology, psychiatry and allied health care professions. PhD studies.

How to apply: http://www.kcl.ac.uk/study/postgraduate/apply/taught-courses.aspx

About Postgraduate Study at King’s College London:

To study for a postgraduate degree at King’s College London is to study at the city’s most central university and at one of the top 20 universities worldwide (2015/16 QS World Rankings). Graduates will benefit from close connections with the UK’s professional, political, legal, commercial, scientific and cultural life, while the excellent reputation of our MA and MRes programmes ensures our postgraduate alumni are highly sought after by some of the world’s most prestigious employers. We provide graduates with skills that are highly valued in business, government, academia and the professions.

Scholarships & Funding:

All current PGT offer-holders and new PGT applicants are welcome to apply for the scholarships. For more information and to learn how to apply visit: http://www.kcl.ac.uk/ioppn/study/prospective-students/Masters-Scholarships.aspx

Free language tuition with the Modern Language Centre:

If you are studying for any postgraduate taught degree at King’s you can take a module from a choice of over 25 languages without any additional cost. Visit: http://www.kcl.ac.uk/mlc

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Sponsored by the NIHR Rare Diseases Translational Research Collaboration, this new course is part of the MPhil in Clinical Science degree programme. The objective of the course is to equip students with a strong foundation in the fundamental techniques of clinical and translational research in rare diseases, applying contemporary research tools to clinically relevant areas of investigation.

The bespoke rare disease research training will be taught by Cambridge academics and industry, and will incorporate a research project focused on rare diseases. Each student is allocated an individual supervisor, who will provide support throughout the course and help build a customised training programme.

The MPhil includes formal modular teaching in core experimental medicine modules (Statistics, Epidemiology, and Practical Aspects of Clinical Research) as well as specialist modules in Genetics and Rare Diseases. In addition, all students will have the opportunity to undertake a relevant 12 week research project with one of our outstanding supervisors, including clinicians across a range of specialities, geneticists, basic biomedical scientists and bio-medical industry partners. It also aims to provide students with broad research, study and communication skills.

See the website http://www.graduate.study.cam.ac.uk/courses/directory/cvmdmprad

Course detail

Upon successful completion of the MPhil graduates will have developed a strong foundation in the fundamental knowledge and techniques required to enable them to undertake clinical and translational research in rare diseases. They will be able to apply contemporary research tools to clinically relevant areas of investigation.

The MPhil programme will produce clinical researchers who are competitive in seeking research support and who are knowledgeable about the complex issues associated with conducting sound clinical research and trials.

Format

The course consists of core modules in Practical Aspects of Clinical Research, Statistics, Epidemiology; as well as bespoke modules in Genetics and Rare Diseases, timetabled over two terms. Students will be allocated mentor groups to work on a group research project; and all students will be allocated/or negotiate an individual 12 week research project for which they will submit a thesis. The course is examined by two sat exams and thesis assessment.

Assessment

Students are expected to submit a thesis covering the research project undertaken in the second and third terms. There is a maximum length of 15000 words.

Students will sit two exams of 2 hours each. The exams will be multiple choice and structured answers.

Students are required to present their work to their supervisors lab and a supervisor report is submitted to the programme directors - this is not assessed but is used as an indication of the progress of the student.

The full-time components of the course are completed by the end of July. However, to complete the course, students will be required to attend a viva in person on a date to be set in August or early September.

Continuing

Students who are progressing well, have the support of a Principal Supervisor, and have the necessary funding, may apply during the year to continue to a PhD on successful completion of their MPhil. Such students will need to gain a pass mark of 70% or more in the MPhil examination.

How to apply: http://www.graduate.study.cam.ac.uk/applying

Funding Opportunities

There is an opportunity for UK students to apply for one of two NIHR BRC- Rare Diseases scholarship of £6500 each to supplement University/college fees.

Information on the application procedure is available from Clinical Academic Training Office - [email protected]

General Funding Opportunities http://www.graduate.study.cam.ac.uk/finance/funding

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The MSc in Genetic and Genomic Counselling is designed to give students a working knowledge of the principles and practice of Genetic Counselling which will qualify them to practice as Genetic and Genomic Counsellors. The programme will be delivered by University of Glasgow staff in collaboration with NHS staff from the West of Scotland Genetics Service, so that a current perspective on both laboratory diagnostics and clinical services will be obtained. This programme is accredited by the UK Genetic Counsellor Registration Board.

Why this programme

-◾Teaching is based at the Queen Elizabeth University Hospital (QEUH), which includes adult services, children’s services and maternity services, as well as one of the largest diagnostic laboratories in Europe, and a new, purpose-built teaching and learning facility. The close collaboration between University and NHS staff ensures that the MSc in Genetic and Genomic Counselling provides a completely up-to-date representation of genetic services.
◾Counselling and psychology theoretical and research-focused courses are delivered by University staff trained in psychology, providing a firm foundation for the subsequent acquisition of knowledge and skills in genetic counselling facilitated by GCRB-registered Genetic Counsellors.
◾The University of Glasgow Medical Genetics Teaching Staff won the 2014 UK-wide Prospects Postgraduate Awards for the category of Best Postgraduate Teaching Team (Science, Technology & Engineering), to recognise and reward excellence and good practice; they were also finalists in the 2013 awards and are finalists in the category of "Outstanding support for students" in The Herald Higher Education Awards for Scotland in association with UWS 2016.
◾You will develop your skills in problem solving, evaluation and interpretation of diagnostic data, communication of the results of genome testing to patients, literature searches, scientific writing, oral presentations, poster presentations and team working.
◾The widely used textbook “Essential Medical Genetics” is co-authored by a member of the core teaching team, Professor Edward Tobias.

Programme structure

Component courses are as follows:

Genetic Disease in Clinical Practice

This course is designed in collaboration with the West of Scotland Genetics Service to give students a working knowledge of the principles and practice of Clinical Genetics which will allow them to evaluate, choose and interpret appropriate genetic investigations for individuals and families with genetic disease, and explore the links between genotype and phenotype.

Case Investigations in Medical Genetics

Students will work in groups to investigate complex clinical case scenarios: decide appropriate testing, analyse results from genetic tests, reach diagnoses where appropriate and, with reference to the literature, generate a concise and critical group report.

Distress or disorder: reactions to a medical diagnosis

Note: this 10 credit course may be taken by visiting students, for example as professional development.

This course outlines the process of psychosocial adjustment to a diagnosis or test result allowing participants to establish if and when a distress reaction develops into an adjustment disorder. The implications of diagnosis are explored and evidence considered allowing informed decisions about appropriate referrals to other agencies.

Patient empowerment: supporting decisions relating to new diagnoses

Note: this 10 credit course may be taken by visiting students, for example as professional development.

This course reflects on evidence and experience to explore the psychological and social impact of a diagnosis, or illness, and provides strategies to support resilience and coping in patients. Factors related to lived experience, personal beliefs and values, culture, adjustment processes, decision-making, misconceptions, secrecy and guilt are considered to equip participants in the promotion of patient-centred care.

Effective listening and communication skills

Note: this 10 credit course may be taken by visiting students, for example as professional development.

With a focus on experiential learning and student led study, this course outlines the role of counselling skills to facilitate adjustment and to allow an individual to come to terms with change in a safe way to minimise impact. The focus will be on the theory supporting counselling, developing key listening and communication skills and on establishing reflective practice.

Genetic counselling in clinical practice

This course is designed in collaboration with the West of Scotland Clinical Service, and will be delivered by NHS staff, to provide students with in depth understanding of the practical skills required in genetic counselling. The course will facilitate development of appropriate critical understanding, reflective practice and skills in relation to genetic counselling for providing accurate complex genetic information for patients and their families.

Social science research methods

The research methods course will focus on developing students’ research skills primarily in questionnaire-based qualitative and quantitative observational research methods and students will be introduced to ethics procedures for the college of MVLS.

Community placements 1 & 2

These placements, for 16 days and 20 days respectively, will each take place in one or more care settings for individuals with complex needs (adults or children or both) to enable students to gain insight into effects of complex needs on affected individuals and on their family.

Genetic counselling placement 1 & 2

These placements, for eight weeks and six weeks respectively, in different genetics centres will allow students to observe clinical practice in a variety of contexts, and to undertake relevant tasks under supervision within a clinical team that is delivering a genetic service, to enable the student to develop their own skills as a future genetic counsellor. Following each placement students will discuss and share experiences, facilitated by one of the NHS lead team and a counselling supervisor, to further develop their ability to deal with practical and emotional challenges in genetic counselling.

Clinical genomics

This course will provide an overview of the clinical applications of genomic approaches to human disorders, particularly in relation to clinical genetics, discussing the methods and capabilities of the new technologies. Tuition and hands-on experience in data analysis will be provided, including the interpretation of next generation sequencing reports.

Career prospects

The programme aims to provide students with skills to work as Genetic Counsellors. This programme is accredited by the Genetic Counsellor Registration Board (GCRB) producing graduates who are eligible for entry as a ‘trainee genetic counsellor’.

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This Clinical Pharmacology degree programme offers focused training which integrates basic and clinical sciences, and equips students with the essential skills required to function effectively as a clinical pharmacologist in the 21st century. As a student on the MSc Clinical Pharmacology programme, you will acquire core skills, enabling an appreciation of how to apply clinical pharmacological, regulatory and ethical principles to the optimisation of therapeutic practice and clinical research. Crucially, in addition to a firm grasp of the principles of molecular pharmacology, you will also gain foundational knowledge in the emerging science of pharmacogenomics and personalised medicine.

Why this programme

◾This Clinical Pharmacology MSc is one of only a few UK postgraduate programmes that cover clinical pharmacology in sufficient detail to allow you to make an informed choice about pursuing clinical pharmacology as a career.
◾You will learn the basics of molecular genetics and population genetics as applied to pharmacogenetics and gene therapy.
◾You will have the opportunity to gain hands-on experience in molecular methods and analysis along with critical interpretation of genomic literature. This will enable you to analyse, synthesise and formulate an action plan for personalised patient care.
◾You will gain the knowledge and experience necessary to engage in and contribute to discussions about therapeutic issues in the commercial and academic research environments. As part of the MSc Clinical Pharmacology degree, you will undertake your own research project under expert supervision, which will allow you to consolidate your knowledge and apply the skills you have acquired.
◾At every stage of the MSc Clinical Pharmacology you will benefit from the close involvement of clinical academics and visiting lecturers from the pharmaceutical industry and national drug regulatory bodies: the programme is specifically designed to prepare graduate for future senior roles within the pharmaceutical medicine. Guest lecturers have recently included staff from Pfizer, Servier, Johnson & Johnson and the Scottish Medicines Consortium.

Programme structure

You will attend lectures, seminars and tutorials and take part in lab, project and team work.

Core courses
◾Principles of Pharmacology
◾Drug Disposition
◾Pharmaceutical Medicine
◾Topics in Therapeutics – General Topics and Cardiovascular Drugs
◾Topics in Therapeutics – Commonly Used Drugs
◾Medical Statistics 1
◾Medical Statistics 2
◾Pharmacogenomics & Molecular Medicine – Fundamentals of Molecular Medicine
◾Pharmacogenomics & Molecular Medicine – Applied Pharmacogenomics & Molecular Medicine

In addition you will undertake a dissertation/project.

Career prospects

Career opportunities include positions in academia, health care and the pharmaceutical industry; returning to more advanced positions within a previous clinical environment (eg pharmacicts, clinicians); and PhD study.

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The science of human genetics has been transformed in the past decade. Following the sequencing of the entire human genome, a wealth of resources is now available to researchers aiming to identify the genetic variants that influence human health. These findings will shed light on the underlying molecular pathology of many diseases that are poorly understood at present, eventually paving the way for novel treatment and prevention strategies. The speed at which these discoveries are being made is accelerating, and it is likely that molecular genetics will soon underpin much of modern medicine.

Career Pathways:
The MSc in Human Molecular Genetics programme is designed to prepare you for a genetics research career, either in human gene function and genetic disease, or molecular approaches to diagnosis and health care biotechnology. It provides a broad grounding in Human Genetics, with emphasis on molecular aspects, to give a solid basis for subsequent academic or industrial research, or for entry to NHS Genetics training. Approximately 40% of our students go on to do a PhD, 40% become research assistants/associates, while others go on to jobs in industry or further studies (bioinformatics/computing medicine). One or two students every year enter the NHS in clinical genetics training posts.

Programme Structure:
You will study the fundamentals of human and molecular genetics, models of inheritance for rare and common/ complex polygenic diseases, cytogenetics, analytical methods in human genetics and genomics, animal models and transgenesis, gene therapy, epigenetics, cancer genetics and an introduction to clinical genetics and genetic counselling services.

There are four weeks of intensive laboratory practical sessions, as well as computer science practicals applied to problems in genetics, genomics and bioinformatics, regular research seminars on site, student seminar and journal presentations, study group activities and a six-month full-time research project in the summer.

The programme is based on an average 20 hours contact time per week. This will vary between 15 hours in most weeks and approximately 40 hours during intensive practicals and projects. Private study time is included within the schedule: you are expected to contribute an additional 10-15 hours private study per week to the course. We do not recommend you try to support yourself by taking a part-time employment whilst studying as your work may suffer.

Assessment:
There are 3 x 3-hour written papers in late February, coursework assessments (poster presentation, analytical methods in genetics, oral presentation), a project report and a viva examination in September.

Programme Location:
The programme is primarily based at Hammersmith Campus in West London although some teaching modules are held at St Mary's Campus and the Northwick Park Campus.

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About the course

This MSc gives students excellent postgraduate training, and leads to exciting careers in research, industry, the NHS and other clinical institutions. Many of our graduates have also gone on to study bioscience at PhD level.

You’ll develop an in-depth knowledge of medical and molecular genetics, and receive clinical genetics training to prepare you for a research project in a modern research facility. You’ll have the chance to collaborate with top genetics research laboratories and clinical partners.

This MSc was developed in partnership with the Sheffield Diagnostic Genetics Service (NHS), which is a world-renowned clinical genetics facility. This relationship is unique to this course and gives you the opportunity to be taught by the Director of the Sheffield Diagnostic Genetics Service, Sheffield Children’s Hospital NHS Foundation Trust, 
and their Head of Pharmacogenetics.

Where your masters can take you

Our graduates work in health care, pharmaceuticals, food safety and production, brewing and agrochemicals. Many of our masters students go on to do a PhD then pursue a career in research; others have gained entry to the prestigious NHS Scientist Training Programme (STP).

An international reputation

The 2014 Research Excellence Framework (REF) ranks Sheffield No 1 for biomedical research and in the UK top five for biological sciences generally. We have regular seminars from distinguished experts, and our motivated staff undertake collaborative research ranging from biotechnology to medicine.

Teaching and assessment

Our masters courses give you a solid grounding in experimental science, with personal supervision and tutorials by experienced scientists, based in modern and well-equipped labs, leading on to a research project in which you design and conduct your own research. You will learn cutting edge science from research leaders, and gain practice in reading the scientific literature and writing reports. Assessment is based on a combination of coursework, project work, formal examinations and a dissertation.

Modules

Genome Stability and Genetic Change; Human Genetics I; Human Genetics II; Advanced Research Topics; Laboratory Techniques in Molecular Bioscience; Literature Review; Research Project.

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This new Master’s degree will provide an in-depth knowledge of the theory and practical skills of clinical paediatrics, including pathology, diagnosis and management. The programme combines lectures and seminars at the UCL Great Ormond Street Institute of Child Health in year one with direct exposure to clinical practice in Great Ormond Street Hospital in year two.

Degree information

The programme will include disease pathology, the assessment of patients and the different therapies available, as well as their limitations and side effects. Students will have the unique opportunity to directly observe the implementation of clinical knowledge in the diagnosis and treatment of a wide range of paediatric disease.

Students undertake modules to the value of 360 credits.

The programme consists of eight core modules (180 credits), four optional modules (60 credits), a dissertation report (60 credits) and a case-based portfolio (60 credits).

Core modules
-Evidence-based Child Health
-Research Methodology and Statistics
-Specialist Paediatrics I (Acute)
-Specialist Paediatrics II (Chronic)
-Clinical Practice: Acute Paediatrics*
-Clinical Practice: Chronic Paediatric Conditions*
-Clinical Practice: Health Service Structure and Specialised Services*
-Clinical Practice: Process Mapping via the Patient Journey*
*All Clinical Practice core modules are taken in year two

Optional modules
Students choose four from the following in year one:
-Clinical Genomics and Rare Diseases
-Epidemiology for Child Health
-Healthy Child Programme 0-18 years
-Immunisation and Communicable Diseases
-Leadership and Professional Development
-Nutrition, Growth and Physical Activity
-Respiration through Life, Health and Disease
-Safeguarding in Children and Children in Society

Dissertation/report
All students undertake an independent research project in their first year culminating in a dissertation of 10,000 words. In the second year, students complete a case-based portfolio.

Teaching and learning
The programme is delivered through a combination of lectures, seminars, workshops and clinical practice observation. Assessment is through unseen written examinations, essays, research posters, assessed seminars, reflective diaries, and simulated clinical scenarios.

Careers

The programme provides an ideal foundation for further doctoral research in this field and/or a career in research and evidence-based practice in paediatrics.

Employability
Students will learn practical academic and clinical skills in acute and chronic paediatric practice and will be able to apply these in their everyday working environment.

Why study this degree at UCL?

The UCL Great Ormond Street Institute of Child Health pursues an integrated, multidisciplinary approach to enhance understanding, diagnosis, therapy and prevention of childhood diseases. Our research and our educational portfolio covers a broad range of paediatric issues, from molecular genetics to population health sciences, and our structure facilitates interdisciplinary work and allows flexibility for the development of new areas of investigation.

Our close relationship with the Great Ormond Street Hospital for Children means that much of our research and teaching is carried out on a joint basis. Students benefit from excellent facilities in both laboratory and non-laboratory subjects.

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This intense course focuses on the molecular and genetic factors of human diseases. Understanding those factors is crucial to the development of therapies.

After you've completed the non-clinical elements of the MSc in Molecular Medicine, you’ll spend 20 weeks with a clinical team, working on a particular health or disease area.

You could work primarily with either a clinical research team or a clinical practice team – depending on your preferred choice and the availability of attachments.

The course will give you a critical understanding of how molecular medicine is being applied to real problems in a particular clinical area. It is assessed mainly through written coursework and dissertations.

Core modules

From Genome to Gene Function
Human Gene Bioinformatics
Human Disease Genetics
Modulating Immunity
Literature Review
Laboratory Techniques
Clinical Attachment Presentation Module

Examples of optional modules

A wide choice of pathways (related to the field of your clinical attachment) which includes:

Virulence Mechanisms of Viruses and Fungi (Microbes and Infection)
Molecular and Cellular Basis of Diseases (Experimental Medicine)
Vascular Cell Biology (Cardiovasular)
The Molecular Basis of Tumorigenesis and Metastasis (Cancer)
Modelling Protein Interactions (Genetic Mechanisms)

Special options for the clinical attachment are:

Clinical Attachment
Clinical Research Project

Teaching

Lectures
Tutorials
Seminars
Clinical Attachment

Assessment

Essays
Portfolio work
One Statistic Exam
Dissertation

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