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Masters Degrees (Cancer Immunotherapy)

We have 16 Masters Degrees (Cancer Immunotherapy)

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The area of cancer immunotherapy considers how to use conventional therapies including surgery, radiation and chemotherapy. Read more
The area of cancer immunotherapy considers how to use conventional therapies including surgery, radiation and chemotherapy. Whilst these treatment have served well and new drugs will continue to be designed, clinical trials over the last five years have shown that boosting the body’s immune system, whose main task is to deal with invading pathogens, can help our immune system to destroy tumour cells. Many of the new immunotherapies may be tested in combination with more conventional treatments or tested alone, but investigators and oncologists now believe immunotherapy, initially combined with pharmacological treatments, will soon provide curative therapies and certainly give many patients a new lease of life.

More about this course

Worldwide the incidence of cancer is increasing, and is expected to reach 22 million new cases per year by 2030. In addition to treatments such as radiotherapy and surgery, chemotherapy has a vital role to play in prolonging the lives of patients.

The aims of the Cancer Immunotherapy MSc are to:
-Provide an in-depth understanding of the molecular targets at which the different classes of anticancer drugs are aimed, and of how drug therapies are evolving
-Review the biology of cancer with respect to genetics, pathological considerations, and the molecular changes within cells which are associated with the progression of the disease
-Enhance intellectual and practical skills necessary for the collection, analysis, interpretation and understanding of scientific data
-Deliver a programme of advanced study to equip students for a future career in anti-cancer drug and immunotherapy development
-Cover new areas in immunotherapy (some of which may enhance existing pharmacological therapies including: History of immunotherapy and review of immune system; Monoclonal antibodies in cancer therapy and prevention; DNA vaccines against cancer; Adoptive T cell therapy; Dendritic cell vaccines; Antibodies that stimulate immunity; Adjuvant development for vaccines; Epigenetics and cancer: improving immunotherapy; Immuno-chemotherapy: integration of therapies; Exosomes and Microvesicles (EMVs) in cancer therapy and diagnosis; Dendritic cell vaccine development and Pox virus cancer vaccine vectors; Microbial causes of cancer and vaccination

Students will have access to highly qualified researchers and teachers in pharmacology and immunology, including those at the Cellular and Molecular Immunology Research Centre. Skills gained from research projects are therefore likely to be highly marketable in industry, academia and in the NHS. Students will be encouraged to join the British Society of Immunology and the International Society of Extracellular Vesicles.

Assessment is a combination of coursework, which includes tests and essays, the research project and its oral defence and examination.

Modular structure

The modules listed below are for the academic year 2016/17 and represent the course modules at this time. Modules and module details (including, but not limited to, location and time) are subject to change over time.

Year 1 modules include:
-Advanced Immunology (core, 20 credits)
-Cancer Immunotherapy (core, 20 credits)
-Cancer Pharmacology (core, 20 credits)
-Cancer: Diagnosis and Therapy (core, 20 credits)
-Molecular Oncology (core, 20 credits)
-Research Project (core, 60 credits)
-Scientific Frameworks for Research (core, 20 credits)

After the course

Students will have many opportunities to work in industry. There are established industries working hard to develop cancer immunotherapies including Bristol-Myers Squibbs, MERCK, AstraZeneca and Roche. There are also an innumerate number of start-up companies appearing including Omnis Pharma, UNUM Therapeutics and Alpine Immune Sciences.

Students will also have ample opportunity for future postgraduate study either within the School of Human Sciences and the Cellular and Molecular Immunology Centre at the MPhil/PhD level or beyond, even with some of our research partners within the UK, Europe and beyond.

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This programme aims to provide you with a clear understanding of the scientific basis underlying the principles and practice of treating cancer. Read more
This programme aims to provide you with a clear understanding of the scientific basis underlying the principles and practice of treating cancer.

This will be underpinned by a thorough knowledge of cancer biology and pathology and research methodologies.

This knowledge will provide an excellent grounding in the development, use and evaluation of cancer therapies, which will enhance career prospects in many areas of early phase clinical trials and clinical drug development in the cancer setting.

Compulsory Modules

• Ablative Therapies
• Cancer Biology
• Cancer Pharmacology
• Cancer Prevention & Screening
• Drug Development
• Molecular Diagnostic & Therapeutics
• Molecular Targeted Therapies and Immunotherapy for Blood Cancer
• Research Methods
• Site Specific Tumour Treatment

Elective Modules

• Genomic Approaches to Human Diseases
• Paediatric & Adolescent Oncology
• Pathology of Cancer

Core Module for MSc

• Dissertation.

Barts Cancer Institute is a Cancer Research UK Centre of Excellence and one of the leading cancer institutes in the country.
Based in the heart of London, our programmes are all taught by experts in the field.

Find out more about the BCI at http://www.bci.qmul.ac.uk/study-with-us

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This programme aims to provide you with a clear understanding of the scientific basis underlying the principles and practice of clinical oncology and the development, evaluation and implementation of new treatments. Read more
This programme aims to provide you with a clear understanding of the scientific basis underlying the principles and practice of clinical oncology and the development, evaluation and implementation of new treatments.

This will be underpinned by a thorough knowledge of cancer biology and pathology, drug development and research methodologies.

This knowledge will provide you with a good grounding in oncology within a clinical setting which will enhance prospects for those wanting to pursue a clinical academic career.

Compulsory Modules

• Ablative Therapies
• Cancer Biology
• Cancer Pharmacology
• Cancer Prevention & Screening
• Drug Development
• Genomic Approaches to Human Diseases
• Imaging
• Paediatric & Adolescent Oncology
• Pathology of Cancer
• Research Methods
• Site Specific Tumour Treatment

Elective Modules

• Biological Therapies
• Molecular Targeted Therapies and Immunotherapy for Blood Cancer

Core Module for MSc

• Dissertation

Barts Cancer Institute is a Cancer Research UK Centre of Excellence and one of the leading cancer institutes in the country.
Based in the heart of London, all our programmes are taught by experts in the field.

To find out more about BCI visit http://www.bci.qmul.ac.uk/study-with-us

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This programme aims to respond to a national and international need for clinicians, scientists and allied health professions who can apply a molecular approach to the investigation, diagnosis and management of clinical disease. Read more
This programme aims to respond to a national and international need for clinicians, scientists and allied health professions who can apply a molecular approach to the investigation, diagnosis and management of clinical disease.

We will provide you with theoretical and practical knowledge of modern molecular technologies as applied to human disease, with an emphasis on cancer, and train you in the application and interpretation of advanced molecular technologies.

Compulsory Modules

• Basic Pathology
• Cancer Biology
• Cancer Prevention & Screening
• Genomic Approaches to Human Diseases
• Molecular Diagnostic & Therapeutics
• Molecular Pathology of Solid Tumours
• Research Lab Skills
• Research Methods

Elective Modules

• Introduction to Bioinformatics
• Biological Therapies
• Molecular Targeted Therapies and Immunotherapy for Blood Cancers

Core Modules for MSc

• Lab project



Barts Cancer Institute is a Cancer Research UK Centre of Excellence and one of the leading cancer institutes in the country.
Based in the heart of London, our programmes are all taught by experts in the field.

Find out more about the BCI at http://www.bci.qmul.ac.uk/study-with-us

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Improved global life expectancy has resulted in a cancer epidemic. It is well recognised that accurate early diagnosis is an essential aspect of the administration of increasingly expensive and tailored cancer treatment care plans. Read more
Improved global life expectancy has resulted in a cancer epidemic. It is well recognised that accurate early diagnosis is an essential aspect of the administration of increasingly expensive and tailored cancer treatment care plans.

The Biomedical Sciences (Cancer Biology) MSc programme has been devised to provide knowledge of key aspects of this increasingly important disease area.

You will become familiar with the genetic and cellular changes occurring in both solid and blood-borne cancers, the current and emerging technological approaches for diagnosis of the disease and the effect on pertinent cellular changes on patient prognosis. Studies on populations and the influence of genotypic variation will ensure that you are qualified to make sense of cancer statistics.

You are able to tailor your programme by selecting from a menu of option modules and pursuing a research project in an area ranging from molecular through to cellular or tissue-based aspects of cancer.

During the course you will join our thriving research environment and will have access to excellent laboratory facilities within the Faculty. On successful completion of the course you will be equipped to take forward your career with an in-depth knowledge of this increasingly common disease area.

Modules

The following modules are indicative of what you will study on this course.

Core modules
-ADVANCED CANCER BIOLOGY
-CELL SIGNALLING AND GENETICS
-MOLECULAR SCIENCE AND DIAGNOSTICS
-POSTGRADUATE PROJECT
-POSTGRADUATE RESEARCH METHODS

Option modules
-COMMUNICATING SCIENCE
-EXTENDED POSTGRADUATE PROJECT
-IMMUNOPATHOLOGY
-IMMUNOTHERAPY
-MOLECULAR AND CELLULAR THERAPEUTICS
-SYSTEMS BIOLOGY

Associated careers

After graduation, you will be equipped with the skills and knowledge to pursue a range of cancer-focused careers including appointments in diagnostic laboratories, academic, biotechnological and pharmaceutical research.

As a graduate of this course, you will be ideally placed to play an essential role in both diagnosis and improved care of cancer patients. Opportunities are also available to pursue a career in clinical trials and in areas such as data analysis and public health.

Professional recognition

The course is accredited by the Institute of Biomedical Science (IBMS).

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This is a full-time 1 year MSc programme suitable for biomedical or life scientists who wish to acquire an extensive knowledge and key skills relating to the fundamental molecular and cellular regulation of immunity and its application to the treatment of disease. Read more
This is a full-time 1 year MSc programme suitable for biomedical or life scientists who wish to acquire an extensive knowledge and key skills relating to the fundamental molecular and cellular regulation of immunity and its application to the treatment of disease. The programme will be delivered by world leaders at the forefront of immunology and immunotherapy research, each with an internationally renowned research group.

Over the past few years significant advances have been made in our understanding of the molecular and cellular control of immune responses. These discoveries are now being translated into the design and testing of immunotherapeutic interventions for a range of diseases including cancer, autoimmunity and inflammatory disease. This programme is for biomedical or life scientists who wish to extend their knowledge and skills in both immunology and its translation to immunotherapy.

A series of interlinked taught modules cover molecular mechanisms in immune cell differentiation and function, autoimmunity, transplant and tumour immunology, and inflammation. This is complemented by comprehensive coverage of the latest developments in immunotherapy including the use of microbial products in immunomodulation and vaccination, small molecules and biologics, as well as cellular immunotherapy.

The programme aims to allow you to understand the research process, from the fundamental discoveries at the forefront of immunological research, to the application of novel interventional immune-based therapies.

A key part of the MSc programme is the planning, execution and reporting of a piece of independent study leading to submission of a dissertation. This study will be in the form of an extensive laboratory research project carried out in internationally renowned research groups. Each student will be a fully-integrated member of one of the large number of research teams in a wide variety of topics across both immunology and immunotherapy. We also plan to offer some projects within external biotechnology companies.

About the College of Medical and Dental Sciences

The College of Medical and Dental Sciences is a major international centre for research and education, make huge strides in finding solutions to major health problems including ageing, cancer, cardiovascular, dental, endocrine, inflammatory diseases, infection (including antibiotic resistance), rare diseases and trauma.
We tackle global healthcare problems through excellence in basic and clinical science, and improve human health by delivering tangible real-life benefits in the fight against acute and chronic disease.
Situated in the largest healthcare region in the country, with access to one of the largest and most diverse populations in Europe, we are positioned to address major global issues and diseases affecting today’s society through our eight specialist research institutes.
With over 1,000 academic staff and around £60 million of new research funding per year, the College of Medical and Dental Sciences is dedicated to performing world-leading research.
We care about our research and teaching and are committed to developing outstanding scientists and healthcare professionals of the future. We offer our postgraduate community a unique learning experience taught by academics who lead the way in research in their field.

Funding and Scholarships

There are many ways to finance your postgraduate study at the University of Birmingham. To see what funding and scholarships are available, please visit: http://www.birmingham.ac.uk/postgraduate/funding

Open Days

Explore postgraduate study at Birmingham at our on-campus open days.
Register to attend at: http://www.birmingham.ac.uk/postgraduate/visit

Virtual Open Days

If you can’t make it to one of our on-campus open days, our virtual open days run regularly throughout the year. For more information, please visit: http://www.pg.bham.ac.uk

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This. MRes Cancer Biology. course will give you advanced knowledge of cellular systems. You will learn about the pathogenesis of cancer, cardiovascular disease, diabetes and kidney fibrosis, along with an exploration of current approaches to cancer gene therapy and immunotherapy. Read more

This MRes Cancer Biology course will give you advanced knowledge of cellular systems. You will learn about the pathogenesis of cancer, cardiovascular disease, diabetes and kidney fibrosis, along with an exploration of current approaches to cancer gene therapy and immunotherapy.

Modules

  • Research Methods and Bioethics
  • Research Project
  • Cell Culture and Antibody Technology
  • Biology of Disease

COME VISIT US ON OUR NEXT OPEN DAY!

Visit us on campus throughout the year, find and register for our next open event on http://www.ntu.ac.uk/pgevents.



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The biggest modern breakthrough for cancer treatment has been antibody therapies. An increasing number of biotechnology companies have antibody - or vaccine-based cancer therapies in development. Read more

Overview

The biggest modern breakthrough for cancer treatment has been antibody therapies. An increasing number of biotechnology companies have antibody - or vaccine-based cancer therapies in development. This course aims to attract students interested in tumour immunology who wish to pursue a career either in industry (biotechnology) or academia.

The course covers both antibody and vaccine cancer therapies and explores the immunology of the tumour host interface. In addition, students will learn about intellectual property and how to exploit scientific research in scientific writings, patents and in development of business plans applicable to the biotechnology industry. To gain practical experience in research students will carry out a research project in the field of tumour immunology.

Aims and objectives

- Acquire a specialised knowledge in tumour immunology with particular reference to monoclonal antibody and cancer vaccines
- Develop the critical and analytical power to evaluate scientific literature
- Perform a scientific research project
- Acquire the ability to communicate scientific results orally and in writing
- Learn about business exploitation of cancer therapy

Innovative features of the course

- The only MSc course based entirely on tumour immunology
- Students undertake a substantial research project, during which time they acquire a considerable amount of laboratory-based skills
- A module based entirely on scientific writing and the development of a business plan
- Individuals from industry lecture on the course
- It is suitable for graduates in Life Sciences, Biomedical Sciences and allied subjects and also for people already in suitable employment who wish to improve and update their knowledge and experience
- It attracts students from the UK and worldwide

Student opinions

"I really enjoyed the course. At first I thought it might be too much of a challenge for me to catch up with everyone because I did not do much molecular science, but the lecturers and staff were really helpful. They made sure everyone was on the same level and there was always someone with whom you could speak if you had any problems. Let's just say they are always there if you need help.

The course also focused on the business side as well, which was a nice change. We were also given lectures by people from the industry. All in all, I would have no hesitation in recommending this course to anyone seeking to develop their scientific knowledge, skills and enhance their career prospects."

"The course prepared me for the cut-throat business of securing research funding, patents and the enormous opportunities available in this new and fascinating field.

Nottingham is a wonderful place to study with excellent academic support and several postgraduate social events throughout the year. I thoroughly enjoyed my one year here."

Comments from potential employers (biotechnology companies)

"This subject is currently undergoing massive expansion and yet qualified graduates are difficult to find. The industry as a whole would benefit from having a source of students with this qualification and from our point of view, such a course may provide candidates that are potentially useful to our company."

"A course in cancer immunotherapy would provide valuable training for people wanting to seek a career in the biopharmaceutical industry where much of the research and development effort is focussed on targeted biological therapies for cancer."

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Help improve human or animal health through creating new or more effective drugs and medicines. Learn the research processes used to identify drug targets and develop new therapeutics. Read more

Help improve human or animal health through creating new or more effective drugs and medicines. Learn the research processes used to identify drug targets and develop new therapeutics.

Your studies will combine the biological sciences with chemistry, giving you the skills to target, design, synthesise, create and assess new drugs. You'll also learn about protecting intellectual property, assessing the financial viability of drugs and the pre-clinical and clinical trial processes.

Tailor your studies to your strengths, interests and career goals. You'll learn a mix of academic and practical skills that are closely aligned to the needs of industry.

The Master of Drug Discovery and Development is best suited to very able students with backgrounds in chemistry or relevant life-science subjects such as biochemistry, biomedical science, pharmacy or pharmacology. It is an intensive one-year taught programme, unique in New Zealand.

Learn from the best

Learn from academics and professionals who are leaders in the field and have experience in successfully taking drugs to market. Each course is taught by at least three academics so you'll be exposed to a wide range of expertise.

Drug Discovery and Development is taught by the Schools of Chemical and Physical Sciences and Biological Sciences in collaboration with the University's Ferrier Research Institute and the Centre for Biodiscovery.

You'll be able to take advantage of the research expertise of the Ferrier Research Institute in drug design and development, and if you're doing a Master's, you'll be working alongside the more than 30 scientists who make up the largest carbohydrate research team in the world. The Institute also has its own manufacturing facility so you'll have the opportunity to observe the drug development process from discovery to product.

You'll also benefit from the programme's links with the Centre for Biodiscovery where you will interact with the research teams that are actively discovering, designing and assessing novel bioactive compounds.

Drugs in the real world

Get wise to the real-world issues facing pharmaceutical development and make the most of the hard-earned experiences of staff who have worked in the local and international biotech industry. Learn not only how to handle chemicals on a large scale, but to develop the mindset to do this in a way that is safe, reliable and robust—so you end up providing medicines that will change people’s lives.

Victoria offers three postgraduate qualifications in Drug Discovery and Development. Choose the one that suits your career goals, time constraints and financial situation.

  • Master of Drug Discovery and Development
  • Postgraduate Diploma in Drug Discovery and Development
  • Postgraduate Certificate in Drug Discovery and Development

If you begin by enrolling in the Certificate or Diploma programme you can continue on to complete your Master's. Or if you enrol in the Master's but can't complete it, for whatever reason, you may have completed enough points to be awarded a Certificate or Diploma.

What you'll study

Each qualification includes the core courses DRGD 401 Chemical Biology and Drug Discovery, and a choice between DRDG 402 Drug Design or CHEM 421 Organic Chemistry and Bio-organic Chemistry.

After that you'll choose from selected courses from the study areas of Drug Discovery and Development, Biomedical Science, Biotechnology, Chemistry, Clinical Research and Microbiology.

All three qualifications give you the opportunity to do at least some research.

Postgraduate Certificate

You'll complete four courses worth 60 points made up of the two core courses and two further choices.

Postgraduate Diploma

You're likely to take seven courses that will include the two core courses, your elective options and the 30-point Research Preparation course.

Master's

You'll study for your Master's in two parts over three trimesters. In Part 1, the first two trimesters, you're likely to take seven courses that will include the core courses and a 30-point Research Preparation course.

In Part 2, you'll complete a full research project. Choose between DRDG 561 Applied Research Project, where you'll complete one or more problem-solving projects, or DRGD 590 Research Project, where you'll focus on medicinal chemistry and the formulation of active pharmaceutical products. In some cases you may be able to replace the research project with the thesis course DRGD 595.

Your Master's may be endorsed with a specialisation in either Drug Discovery, Drug Development or Chemical Biology. Check the requirements to find out what you need to do for these.

Workload and duration

You can expect a workload of 40–45 hours a week for much of your studies.

The MDDD can be completed in 12 months full time, or in two years of part-time study but you'll need to discuss this option with the programme directorfirst. The Diploma will take you two trimesters and the Certificate one trimester.

Location

You'll study at Wellington's Kelburn campus where you will have access to state-of-the-art research facilities. Students doing a research programme will also work in partnership the world-renowned Ferrier Research Institute in Lower Hutt.

Research topics

Be part of a dynamic and collaborative scientific research community. Past students' research areas in drug discovery and development have included:

  • development of a new scaled-up catalytic process for a high value fine chemical
  • isolation and characterisation of a novel bioactive from a New Zealand marine organism
  • formulation of a novel therapeutic for cancer immunotherapy.

Community

Become part of an active community of scientists. Postgraduate study at Victoria will help you build valuable relationships and networks with peers, university staff and future colleagues. You'll have unprecedented access to world industry leaders who visit as guest lecturers and run seminars with students.

Careers

You'll have the broad skills you need to work in drug discovery in companies, universities, research institutes or with drug regulatory authorities. You might work within the pharmaceutical, bioanalytical or chemical industries, or take your skills into nutraceuticals or agrichemicals.



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Your programme of study. Immunology is linked to our ability to remain healthy and free of disease - fighting off infections and disease and understanding our genetic factors and risk factors in inheriting disease. Read more

Your programme of study

Immunology is linked to our ability to remain healthy and free of disease - fighting off infections and disease and understanding our genetic factors and risk factors in inheriting disease. You look at behavioural factors and their links to disease to understand protection methods and you go into the detail of bioinformatics and genomics to understand DNA and analyse within practical research when you test for specific issues such as stress, hunger and so on and responses in the body.

The programme is designed for you to develop your academic knowledge of immunology and its relevance to disease with analysis and research skills designed to enhance your career prospects, or continue to PhD. You can use your training within educational establishments to apply training, work in patents, science outreach and public engagement.

Focusing on the relevance of the immune response in the maintenance of health and development of disease, graduates will be able to attain the intellectual and practical skills needed to address both theoretical and technical aspects of modern biomedical research.

In common with the other molecular biosciences Masters courses, the MSc in Immunology & Immunotherapy builds on recent advances in genomics to understand the generation of immunological diversity at a cellular level, how this imparts variability in immune responses at the individual and population level and the relevance of the immune system in disease areas such as autoimmunity, cancer, allergy and microbial infections.

You may also be interested in the Scottish Innovation Centres research and enterprise work with companies in Scotland to find out more about the possibilities in this area of health science and spin-out research going on from Aberdeen and other universities:

Courses listed for the programme

Semester 1

  • Basic Skills Induction
  • Generic Skills
  • Current Topics in Immunology
  • Introductory Immunology
  • Applied Statistics

Semester 2

  • Host-Pathogen Interactions
  • Genome - Enabled Medicines
  • Research Tutorials
  • Immunogenetics

Find out more detail by visiting the programme web page

Why study at Aberdeen?

  • You will be taught by world leading researchers in immunology and bioscience with practical training in Flow Cytometry analysis
  • You study at one of the largest health campuses in Europe with a teaching hospital, Medical School, and Institute of Medical Sciences plus Rowett Institute on one campus
  • The university ranked 9th in the world and 5th in Europe for international research collaboration (Leiden 2015)

Where you study

  • University of Aberdeen
  • Full Time or Part Time
  • 12 Months Full Time or 24 Months Part Time
  • September start

International Student Fees 2017/2018

Find out about fees:

*Please be advised that some programmes have different tuition fees from those listed above and that some programmes also have additional costs.

Scholarships

View all funding options on our funding database via the programme page

Living in Aberdeen

Find out more about:

  • Your Accommodation
  • Campus Facilities
  • Aberdeen City
  • Student Support
  • Clubs and Societies

Find out more about living in Aberdeen and living costs



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We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments. Read more

We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments.

As a student you will be registered with a University research institute, for many this is the Institute for Cellular Medicine (ICM). You will be supported in your studies through a structured programme of supervision and training via our Faculty of Medical Sciences Graduate School.

We undertake the following areas of research and offer MPhil, PhD and MD supervision in:

Applied immunobiology (including organ and haematogenous stem cell transplantation)

Newcastle hosts one of the most comprehensive organ transplant programmes in the world. This clinical expertise has developed in parallel with the applied immunobiology and transplantation research group. We are investigating aspects of the immunology of autoimmune diseases and cancer therapy, in addition to transplant rejection. We have themes to understand the interplay of the inflammatory and anti-inflammatory responses by a variety of pathways, and how these can be manipulated for therapeutic purposes. Further research theme focusses on primary immunodeficiency diseases.

Dermatology

There is strong emphasis on the integration of clinical investigation with basic science. Our research include:

  • cell signalling in normal and diseased skin including mechanotransduction and response to ultraviolet radiation
  • dermatopharmacology including mechanisms of psoriatic plaque resolution in response to therapy
  • stem cell biology and gene therapy
  • regulation of apoptosis/autophagy
  • non-melanoma skin cancer/melanoma biology and therapy.

We also research the effects of UVR on the skin including mitochondrial DNA damage as a UV biomarker.

Diabetes

This area emphasises on translational research, linking clinical- and laboratory-based science. Key research include:

  • mechanisms of insulin action and glucose homeostasis
  • insulin secretion and pancreatic beta-cell function
  • diabetic complications
  • stem cell therapies
  • genetics and epidemiology of diabetes.

Diagnostic and therapeutic technologies

Focus is on applied research and aims to underpin future clinical applications. Technology-oriented and demand-driven research is conducted which relates directly to health priority areas such as:

  • bacterial infection
  • chronic liver failure
  • cardiovascular and degenerative diseases.

This research is sustained through extensive internal and external collaborations with leading UK and European academic and industrial groups, and has the ultimate goal of deploying next-generation diagnostic and therapeutic systems in the hospital and health-care environment.

Kidney disease

There is a number of research programmes into the genetics, immunology and physiology of kidney disease and kidney transplantation. We maintain close links between basic scientists and clinicians with many translational programmes of work, from the laboratory to first-in-man and phase III clinical trials. Specific areas:

  • haemolytic uraemic syndrome
  • renal inflammation and fibrosis
  • the immunology of transplant rejection
  • tubular disease
  • cystic kidney disease.

The liver

We have particular interests in:

  • primary biliary cirrhosis (epidemiology, immunobiology and genetics)
  • alcoholic and non-alcoholic fatty liver disease
  • fibrosis
  • the genetics of other autoimmune and viral liver diseases

Magnetic Resonance (MR), spectroscopy and imaging in clinical research

Novel non-invasive methodologies using magnetic resonance are developed and applied to clinical research. Our research falls into two categories:

  • MR physics projects involve development and testing of new MR techniques that make quantitative measurements of physiological properties using a safe, repeatable MR scan.
  • Clinical research projects involve the application of these novel biomarkers to investigation of human health and disease.

Our studies cover a broad range of topics (including diabetes, dementia, neuroscience, hepatology, cardiovascular, neuromuscular disease, metabolism, and respiratory research projects), but have a common theme of MR technical development and its application to clinical research.

Musculoskeletal disease (including auto-immune arthritis)

We focus on connective tissue diseases in three, overlapping research programmes. These programmes aim to understand:

  • what causes the destruction of joints (cell signalling, injury and repair)
  • how cells in the joints respond when tissue is lost (cellular interactions)
  • whether we can alter the immune system and ‘switch off’ auto-immune disease (targeted therapies and diagnostics)

This research theme links with other local, national and international centres of excellence and has close integration of basic and clinical researchers and hosts the only immunotherapy centre in the UK.

Pharmacogenomics (including complex disease genetics)

Genetic approaches to the individualisation of drug therapy, including anticoagulants and anti-cancer drugs, and in the genetics of diverse non-Mendelian diseases, from diabetes to periodontal disease, are a focus. A wide range of knowledge and experience in both genetics and clinical sciences is utilised, with access to high-throughput genotyping platforms.

Reproductive and vascular biology

Our scientists and clinicians use in situ cellular technologies and large-scale gene expression profiling to study the normal and pathophysiological remodelling of vascular and uteroplacental tissues. Novel approaches to cellular interactions have been developed using a unique human tissue resource. Our research themes include:

  • the regulation of trophoblast and uNk cells
  • transcriptional and post-translational features of uterine function
  • cardiac and vascular remodelling in pregnancy

We also have preclinical molecular biology projects in breast cancer research.

Respiratory disease

We conduct a broad range of research activities into acute and chronic lung diseases. As well as scientific studies into disease mechanisms, there is particular interest in translational medicine approaches to lung disease, studying human lung tissue and cells to explore potential for new treatments. Our current areas of research include:

  • acute lung injury - lung infections
  • chronic obstructive pulmonary disease
  • fibrotic disease of the lung, both before and after lung transplantation.

Pharmacology, Toxicology and Therapeutics

Our research projects are concerned with the harmful effects of chemicals, including prescribed drugs, and finding ways to prevent and minimise these effects. We are attempting to measure the effects of fairly small amounts of chemicals, to provide ways of giving early warning of the start of harmful effects. We also study the adverse side-effects of medicines, including how conditions such as liver disease and heart disease can develop in people taking medicines for completely different medical conditions. Our current interests include: environmental chemicals and organophosphate pesticides, warfarin, psychiatric drugs and anti-cancer drugs.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.



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Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research. Read more

Understanding the molecular basis of disease

Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research.

Only by dissecting the molecular mechanisms that trigger and advance diseases and dysfunctions can we design effective treatments and medicines. The Research Master's in Molecular Mechanisms of Disease (MMD) offers you an intensive two-year programme that provides you with in-depth knowledge and research experience of disease-related molecular mechanisms. In addition, you will acquire skills such as academic writing and presentation skills and learn how to successfully apply for grants and market yourself.

Passion for molecular biomedical research

As an MMD student you will be part of the unique research community that is found within the Radboud Institute for Molecular Life Sciences (RIMLS). Like you, RIMLS researchers have a strong passion for research. They will assist you throughout the programme with guidance and expertise, supporting you in acquiring knowledge and developing excellent research skills. The RIMLS is one of the research institutes of the Radboud university medical center, so their research is closely linked to the clinic and thus aimed at translating results into treatments for patients. Examples include the translation of insights into the biology of antigen-presenting cells into new immunological cancer therapies and understanding the mutations underlying blindness into the development of gene therapies for patients with inherited blindness.

See the website http://www.ru.nl/masters/mmd

Why study Molecular Mechanisms of Disease at Radboud University?

- You will follow a broad biomedical programme that allows you to specialise in your specific field-of-interest.
- You will have intense daily contact with established researchers.
- You will participate in group-oriented education and be part of a small group of highly motivated national and international students.
- A personal mentor will help you to reflect on your study programme and career perspective.
- You will do two 6-months research internships one of which will be abroad.
- There is a 92% pass rate of MMD students within the two years.
- International MMD students can apply for scholarships from the Radboudumc Study Fund.

Career prospects

There is considerable demand for experts in the molecular biomedical sciences as well as in their application to the development of treatments for diseases such as cancer, autoimmune and inflammatory disorders, and metabolic diseases.

Graduates in MMD are equipped with cutting-edge knowledge of multidisciplinary research in the mechanisms of disease and in state-of-the-art diagnostic methods and technologies. During the programme, you will develop a highly critical, independent approach to problem-solving. You will also acquire the basic management skills needed to lead R&D projects in the biotechnology and pharmaceutical industries.

Most of our graduates will enter an international PhD programme to continue with research in academia or industry.

PhD opportunities

The MSc Molecular Mechanisms of Disease aims to provide all skills and knowledge necessary to rapidly enter an international PhD programme. In the Netherlands and many places in Europe, it is impossible to start a PhD programme directly after obtaining a Bachelor's degree. This research Master’s programme seriously increases your chances for obtaining an excellent PhD training position by giving you a mature perspective and a broad range of experimental approaches. In fact, over 90% of our graduates has started a (funded) PhD project.

The Radboud Institute for Molecular Life Sciences (RIMLS) recruits about fifty PhD students a year. MMD graduates are excellent candidates for these positions. Furthermore, the Radboud university medical centre offers the opportunity for its research-oriented Master's students to write their own research project. The best candidates are awarded a fully funded four-year PhD studentship at the department of their choice.

Our approach to this field

The molecular regulation of cellular processes is crucial for human development, and maintenance of health throughout life. It's evident that cellular malfunction is the cause of common multi-factorial diseases such as diabetes, immune and inflammatory disorders, renal disease, cardiovascular, metabolic and neurodegenerative diseases as well as obesity and cancer.

The Radboud Institute for Molecular Life Sciences (RIMLS) Graduate School plays a key role in developing new therapies for the fight against such diseases. RIMLS aims to improve diagnostics and develop new treatments by generating basic knowledge in the molecular biomedical life sciences and translating it into clinical application and experimental research in patients.

The RIMLS – which is part of Radboud university medical center – offers an exclusive Master's programme in Molecular Mechanisms of Disease. Top researchers and clinicians teach the programme.

Key themes

The MMD programme is organised along three major educational themes which reflect the main research areas present in the RIMLS and which each include both a fundamental and a disease-related aspect:
- Theme 1 Infection, Immunity and Regenerative Medicine / Immunity-related Disorders and Immunotherapy
- Theme 2 Metabolism, Transport and Motion / Metabolic Disorders
- Theme 3 Cell Growth and Differentiation / Developmental Disorders and Malignancies

See the website http://www.ru.nl/masters/mmd

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The course will allow you to expand your understanding of immunology, immunopathology and immunotherapy, to further develop skills in analytical approaches to immunodiagnosis and molecular therapeutics, as well as enhance your competence in the design and execution of a laboratory based project. Read more
The course will allow you to expand your understanding of immunology, immunopathology and immunotherapy, to further develop skills in analytical approaches to immunodiagnosis and molecular therapeutics, as well as enhance your competence in the design and execution of a laboratory based project. You will be able to take a proactive role in research, development, evaluation and implementation of current immunological techniques while perceiving the subject in the broader perspective of health care and scientific progress.

The scope of the modules included will ensure a breadth of knowledge appropriate for the scientific and professional needs of practising immunologists, at the same time making use of your knowledge and experience. This course is designed so that you can plan your own taught programme to match your interests and experience by combining core and optional modules with emphasis on therapeutics, diagnostics, haematology or public health.

Modules

The following modules are indicative of what you will study on this course.

Core modules
-CELL SIGNALLING AND GENETICS
-IMMUNOPATHOLOGY
-IMMUNOTHERAPY
-POSTGRADUATE RESEARCH METHODS
-POSTGRADUATE PROJECT

Option modules
-ADVANCED CANCER BIOLOGY
-EXTENDED POSTGRADUATE PROJECT
-IMMUNOHAEMATOLOGY AND HAEMOSTASIS
-INFECTIOUS DISEASES AND PUBLIC HEALTH
-MOLECULAR AND CELLULAR THERAPEUTICS
-MOLECULAR SCIENCE AND DIAGNOSTICS
-PRINCIPLES OF MOLECULAR MEDICINE
-SYSTEMS BIOLOGY

Associated careers

The course has been designed to provide professionals with a broad range of skills in immunology, immunopathology and immunotherapy. Successful completion of the course will enhance your career prospects in education, in PhD programmes, in academia, research institutes, as well as in pharmaceutical and related industries. UK part-time students are normally employed in hospital or NHSBT laboratories or in research establishments.

You will develop a range of transferable skills that will enhance your employment prospects and research opportunities in the UK or overseas. As an international student with experience in biomedical sciences, following completion of their studies, you will be able to return to your home country to pursue research opportunities or promotion, seek employment as research technician, biomedical scientist, scientific or medical technical officer or research assistant. You may also seek jobs in industry, research or healthcare or apply for further training (biomedical or clinical scientist routes).

Professional recognition

The course is accredited by the Institute of Biomedical Science (IBMS).

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The Graduate Program in Pharmaceutical Sciences, located on the Texas Tech University Health Sciences Center (TTUHSC) campus at Amarillo, Texas offers Masters (M.S.) and Doctoral (Ph.D.) degrees in integrated biomedical/pharmaceutical research as part of the TTUHSC Graduate School of Biomedical Sciences. Read more
The Graduate Program in Pharmaceutical Sciences, located on the Texas Tech University Health Sciences Center (TTUHSC) campus at Amarillo, Texas offers Masters (M.S.) and Doctoral (Ph.D.) degrees in integrated biomedical/pharmaceutical research as part of the TTUHSC Graduate School of Biomedical Sciences.

About the Program

Modern pharmaceutical science encompasses a number of disciplines, including biochemistry, molecular biology, physiology, immunology, pharmacology, pharmaceutics, and medicinal chemistry. The field is unified by the search for novel drug targets and the development of new agents and formulations for the treatment biomedical disease. This includes cutting edge techniques to target drugs to sites of therapeutic action and to reduce adverse effects related to drug metabolism, lack of target selectivity, and pharmacogenetic differences within the human population. PhD’s in pharmaceutical science are well trained for drug discovery and development positions in academic labs, government (e.g., Food and Drug Administration), and the pharmaceutical or biotech industries.
Each student completes a core curriculum including foundation training in biochemistry, physiology, pharmacology and pharmaceutics designed to give students a basic understanding of the biomedical processes by which the body operates and the pharmaceutical agents and delivery systems available to interact with these systems. Electives studies offer the student the opportunity for specialization in more focused areas of interest, including receptor biology, molecular drug action, cell signaling, cancer research, pharmacokinetics, drug metabolism, and biotechnology. Communication, research design, professional skills and ethics are developed throughout the curriculum in complementary courses. Students become immersed in the philosophy of life-long learning and the importance of maintaining and updating their knowledge base as critical, independent thinkers and scientists. The faculty sees this integrated approach as one of the primary strengths of the program, combining cutting-edge molecular and biomedical breakthroughs with modern drug development, targeting and formulation. A broad range of biomedical and pharmaceutical research opportunities are available throughout the department. Focus areas of the Department with links to specific faculty interests are listed below:
Aging/Brain/Neuroprotection/Stroke
Blood Brain Barrier and Neurovascular
Cancer and Molecular Biology & Therapy
Cardiovascular Disease & Regulation
Drug Discovery and Formulation & Pharmacokinetics
Receptor Biology, Cell Signaling & Immunotherapy

Funding

Typically, students may complete a course of study for a Ph.D. degree within 4-5 years or a Masters degree in about half that time (2-2.5 years). Funding is available in the form of stipends ($23,000) from the Department/Graduate School and from individual faculty research resources. These stipends are awarded on a competitive basis to qualifying Ph.D. candidates. Currently, the Department has 43 funded graduate students.

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This course allows you to plan your own taught programme to match your interests and experience by selecting modules from a diverse range of option modules from a diverse range offered by the biosciences masters course in the in the Faculty of Science and Technology, with the advice of the Course Leader. Read more
This course allows you to plan your own taught programme to match your interests and experience by selecting modules from a diverse range of option modules from a diverse range offered by the biosciences masters course in the in the Faculty of Science and Technology, with the advice of the Course Leader. For example, you could combine modules on microbiology and molecular biology or those on haematology and clinical chemistry.

Alternatively, you can combine basic science with study of the communication or commercialisation of science. We also offer the opportunity to consider the increasing role of automation in diagnostic laboratories. Those studying part time are free to develop their module choices as they progress.

Whatever the combination, you will be able to expand your understanding of human diseases, their investigation and therapy, and develop your competence in the design and execution of a laboratory-based project.

Modules

The following modules are indicative of what you will study on this course.

Core modules
-POSTGRADUATE PROJECT
-POSTGRADUATE RESEARCH METHODS

Option modules
-ADVANCED CANCER BIOLOGY
-ADVANCES IN CELLULAR PATHOLOGY
-AUTOMATION IN BIOMEDICAL SCIENCES
-CELL SIGNALLING AND GENETICS
-CELLULAR HAEMATOLOGY
-CLINICAL ASPECTS OF MICROBIAL PHYSIOLOGY AND CHEMOTHERAPY
-CLINICAL ENDOCRINOLOGY AND METABOLISM
-COMMUNICATING SCIENCE
-CONCEPTS AND PRINCIPLES OF HUMAN NUTRITION
-DIAGNOSTIC CELLULAR PATHOLOGY
-DIAGNOSTIC CLINICAL BIOCHEMISTRY
-EXTENDED POSTGRADUATE PROJECT
-IMMUNOHAEMATOLOGY AND HAEMOSTASIS
-IMMUNOPATHOLOGY
-IMMUNOTHERAPY
-INFECTIOUS DISEASES AND PUBLIC HEALTH
-MOLECULAR AND CELLULAR THERAPEUTICS
-MOLECULAR BIOINFORMATICS
-MOLECULAR SCIENCE AND DIAGNOSTICS
-PRINCIPLES OF MOLECULAR MEDICINE
-PRINCIPLES OF PHARMACOLOGY AND DRUG DISCOVERY
-REGENERATIVE MEDICINE
-SCIENCE, TECHNOLOGY AND COMMERCIALISATION
-SYSTEMS BIOLOGY

Associated careers

You will develop a range of transferable skills that will enhance your employment prospects and your research opportunities in the UK or overseas. This course has a diverse intake pf both full and part-time home/EU students range from recent graduates top those working in diagnostic laboratories who wish to gain additional qualification while our international students often have experience in biomedical science laboratories and following completion of their studies will return to their home countries pursue promotion or research opportunities.

Professional recognition

The course is accredited by the Institute of Biomedical Science (IBMS). However students interested in gaining professional registration should consider our Applied Biomedical Science MSc.

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