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Masters Degrees (Autoimmune)

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We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments. Read more

We invite postgraduate research proposals in a number of disease areas that impact significantly on patient care. We focus on exploring the mechanisms of disease, understanding the ways disease impacts patients’ lives, utilising new diagnostic and therapeutic techniques and developing new treatments.

As a student you will be registered with a University research institute, for many this is the Institute for Cellular Medicine (ICM). You will be supported in your studies through a structured programme of supervision and training via our Faculty of Medical Sciences Graduate School.

We undertake the following areas of research and offer MPhil, PhD and MD supervision in:

Applied immunobiology (including organ and haematogenous stem cell transplantation)

Newcastle hosts one of the most comprehensive organ transplant programmes in the world. This clinical expertise has developed in parallel with the applied immunobiology and transplantation research group. We are investigating aspects of the immunology of autoimmune diseases and cancer therapy, in addition to transplant rejection. We have themes to understand the interplay of the inflammatory and anti-inflammatory responses by a variety of pathways, and how these can be manipulated for therapeutic purposes. Further research theme focusses on primary immunodeficiency diseases.

Dermatology

There is strong emphasis on the integration of clinical investigation with basic science. Our research include:

  • cell signalling in normal and diseased skin including mechanotransduction and response to ultraviolet radiation
  • dermatopharmacology including mechanisms of psoriatic plaque resolution in response to therapy
  • stem cell biology and gene therapy
  • regulation of apoptosis/autophagy
  • non-melanoma skin cancer/melanoma biology and therapy.

We also research the effects of UVR on the skin including mitochondrial DNA damage as a UV biomarker.

Diabetes

This area emphasises on translational research, linking clinical- and laboratory-based science. Key research include:

  • mechanisms of insulin action and glucose homeostasis
  • insulin secretion and pancreatic beta-cell function
  • diabetic complications
  • stem cell therapies
  • genetics and epidemiology of diabetes.

Diagnostic and therapeutic technologies

Focus is on applied research and aims to underpin future clinical applications. Technology-oriented and demand-driven research is conducted which relates directly to health priority areas such as:

  • bacterial infection
  • chronic liver failure
  • cardiovascular and degenerative diseases.

This research is sustained through extensive internal and external collaborations with leading UK and European academic and industrial groups, and has the ultimate goal of deploying next-generation diagnostic and therapeutic systems in the hospital and health-care environment.

Kidney disease

There is a number of research programmes into the genetics, immunology and physiology of kidney disease and kidney transplantation. We maintain close links between basic scientists and clinicians with many translational programmes of work, from the laboratory to first-in-man and phase III clinical trials. Specific areas:

  • haemolytic uraemic syndrome
  • renal inflammation and fibrosis
  • the immunology of transplant rejection
  • tubular disease
  • cystic kidney disease.

The liver

We have particular interests in:

  • primary biliary cirrhosis (epidemiology, immunobiology and genetics)
  • alcoholic and non-alcoholic fatty liver disease
  • fibrosis
  • the genetics of other autoimmune and viral liver diseases

Magnetic Resonance (MR), spectroscopy and imaging in clinical research

Novel non-invasive methodologies using magnetic resonance are developed and applied to clinical research. Our research falls into two categories:

  • MR physics projects involve development and testing of new MR techniques that make quantitative measurements of physiological properties using a safe, repeatable MR scan.
  • Clinical research projects involve the application of these novel biomarkers to investigation of human health and disease.

Our studies cover a broad range of topics (including diabetes, dementia, neuroscience, hepatology, cardiovascular, neuromuscular disease, metabolism, and respiratory research projects), but have a common theme of MR technical development and its application to clinical research.

Musculoskeletal disease (including auto-immune arthritis)

We focus on connective tissue diseases in three, overlapping research programmes. These programmes aim to understand:

  • what causes the destruction of joints (cell signalling, injury and repair)
  • how cells in the joints respond when tissue is lost (cellular interactions)
  • whether we can alter the immune system and ‘switch off’ auto-immune disease (targeted therapies and diagnostics)

This research theme links with other local, national and international centres of excellence and has close integration of basic and clinical researchers and hosts the only immunotherapy centre in the UK.

Pharmacogenomics (including complex disease genetics)

Genetic approaches to the individualisation of drug therapy, including anticoagulants and anti-cancer drugs, and in the genetics of diverse non-Mendelian diseases, from diabetes to periodontal disease, are a focus. A wide range of knowledge and experience in both genetics and clinical sciences is utilised, with access to high-throughput genotyping platforms.

Reproductive and vascular biology

Our scientists and clinicians use in situ cellular technologies and large-scale gene expression profiling to study the normal and pathophysiological remodelling of vascular and uteroplacental tissues. Novel approaches to cellular interactions have been developed using a unique human tissue resource. Our research themes include:

  • the regulation of trophoblast and uNk cells
  • transcriptional and post-translational features of uterine function
  • cardiac and vascular remodelling in pregnancy

We also have preclinical molecular biology projects in breast cancer research.

Respiratory disease

We conduct a broad range of research activities into acute and chronic lung diseases. As well as scientific studies into disease mechanisms, there is particular interest in translational medicine approaches to lung disease, studying human lung tissue and cells to explore potential for new treatments. Our current areas of research include:

  • acute lung injury - lung infections
  • chronic obstructive pulmonary disease
  • fibrotic disease of the lung, both before and after lung transplantation.

Pharmacology, Toxicology and Therapeutics

Our research projects are concerned with the harmful effects of chemicals, including prescribed drugs, and finding ways to prevent and minimise these effects. We are attempting to measure the effects of fairly small amounts of chemicals, to provide ways of giving early warning of the start of harmful effects. We also study the adverse side-effects of medicines, including how conditions such as liver disease and heart disease can develop in people taking medicines for completely different medical conditions. Our current interests include: environmental chemicals and organophosphate pesticides, warfarin, psychiatric drugs and anti-cancer drugs.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.



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The only Master’s specialisation in the Netherlands covering the function of our epigenome, a key factor in regulating gene expression and in a wide range of diseases. Read more

Master's specialisation in Medical Epigenomics

The only Master’s specialisation in the Netherlands covering the function of our epigenome, a key factor in regulating gene expression and in a wide range of diseases.
Our skin cells, liver cells and blood cells all contain the same genetic information. Yet these are different types of cells, each performing their own specific tasks. How is this possible? The explanation lies in the epigenome: a heritable, cell-type specific set of chromosomal modifications, which regulates gene expression. Radboud University is specialised in studying the epigenome and is the only university in the Netherlands to offer a Master’s programme in this field of research.

Health and disease

The epigenome consists of small and reversible chemical modifications of the DNA or histone proteins, such as methylation, acetylation and phosphorylation. It changes the spatial structure of DNA, resulting in gene activation or repression. These processes are crucial for our health and also play a role in many diseases, like autoimmune diseases, cancer and neurological disorders. As opposed to modifications of the genome sequence itself, epigenetic modifications are reversible. You can therefore imagine the great potential of drugs that target epigenetic enzymes, so-called epi-drugs.

Big data

In this specialisation, you’ll look at a cell as one big and complex system. You’ll study epigenetic mechanisms during development and disease from different angles. This includes studying DNA and RNA by next-generation sequencing (epigenomics) and analysing proteins by mass spectrometry (proteomics). In addition, you‘ll be trained to design computational strategies that allow the integration of these multifaceted, high-throughput data sets into one system.

Why study Medical Epigenomics at Radboud University?

- Radboud University combines various state-of-the-art technologies – such as quantitative mass spectrometry and next-generation DNA sequencing – with downstream bioinformatics analyses in one department. This is unique in Europe.
- This programme allows you to work with researchers from the Radboud Institute for Molecular Life sciences (RIMLS), one of the leading multidisciplinary research institutes within this field of study worldwide.
- We have close contacts with high-profile medically oriented groups on the Radboud campus and with international institutes (EMBL, Max-Planck, Marie Curie, Cambridge, US-based labs, etc). As a Master’s student, you can choose to perform an internship in one of these related departments.
- Radboud University coordinates BLUEPRINT, a 30 million Euro European project focusing on the epigenomics of leukaemia. Master’s students have the opportunity to participate in this project.

Career prospects

As a Master’s student of Medical Epigenomics you’re trained in using state-of-the art technology in combination with biological software tools to study complete networks in cells in an unbiased manner. For example, you’ll know how to study the effects of drugs in the human body.
When you enter the job market, you’ll have:
- A thorough background of epigenetic mechanisms in health and disease, which is highly relevant in strongly rising field of epi-drug development
- Extensive and partly hands-on experience in state-of-the-art ‘omics’ technologies: next-generation sequencing, quantitative mass spectrometry and single cell technologies;
- Extensive expertise in designing, executing and interpreting scientific experiments in data-driven research;
- The computational skills needed to analyse large ‘omics’ datasets.

With this background, you can become a researcher at a:
- University or research institute;
- Pharmaceutical company, such as Synthon or Johnson & Johnson;
- Food company, like Danone or Unilever;
- Start-up company making use of -omics technology.

Apart from research into genomics and epigenomics, you could also work on topics such as miniaturising workflows, improving experimental devices, the interface between biology and informatics, medicine from a systems approach.

Or you can become a:
- Biological or medical consultant;
- Biology teacher;
- Policy coordinator, regarding genetic or medical issues;
- Patent attorney;
- Clinical research associate;

PhD positions at Radboud University

Each year, the Molecular Biology department (Prof. Henk Stunnenberg, Prof. Michiel Vermeulen) and the Molecular Developmental Biology department (Prof. Gert-Jan Veenstra) at the RIMLS offer between five and ten PhD positions. Of course, many graduates also apply for a PhD position at related departments in the Netherlands, or abroad.

Our approach to this field

- Systems biology
In the Medical Epigenomics specialisation you won’t zoom in on only one particular gene, protein or signalling pathway. Instead, you’ll regard the cell as one complete system. This comprehensive view allows you to, for example, model the impact of one particular epigenetic mutation on various parts and functions of the cell, or study the effects of a drug in an unbiased manner. One of the challenges of this systems biology approach is the processing and integration of large amounts of data. That’s why you’ll also be trained in computational biology. Once graduated, this will be a great advantage: you’ll be able to bridge the gap between biology, technology and informatics , and thus have a profile that is desperately needed in modern, data-driven biology.

- Multiple OMICS approaches
Studying cells in a systems biology approach means connecting processes at the level of the genome (genomics), epigenome (epigenomics), transcriptome (transcriptomics), proteome (proteomics), etc. In the Medical Epigenomics specialisation, you’ll get acquainted with all these different fields of study.

- Patient and animal samples
Numerous genetic diseases are not caused by genetic mutations, but by epigenetic mutations that influence the structure and function of chromatin. Think of:
- Autoimmune diseases, like rheumatoid arthritis and lupus
- Cancer, in the forms of leukaemia, colon cancer, prostate cancer and cervical cancer
- Neurological disorders, like Rett Syndrome, Alzheimer, Parkinson, Multiple Sclerosis, schizophrenia and autism

We investigate these diseases on a cellular level, focusing on the epigenetic mutations and the impact on various pathways in the cell. You’ll get the chance to participate in that research, and work with embryonic stem cell, patient, Xenopus or zebra fish samples.

See the website http://www.ru.nl/masters/medicalbiology/epigenomics

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This Biomedical Sciences degree offers research training for students in order to gain all the required Biomedical Sience entry requirements to proceed to a PhD. Read more
This Biomedical Sciences degree offers research training for students in order to gain all the required Biomedical Sience entry requirements to proceed to a PhD. It is largely based on individual research projects rather than coursework, and allows you to specialise in a particular area of study.

Why this programme

◾Ranked world top 100 for Biological Sciences
◾The Masters in Biomedical Science provides training in a wide range of modern molecular biology techniques required to pursue a research career.
◾You will gain valuable practical research experience by using the skills and techniques acquired during the programme to complete two extensive research projects.
◾The Biomedical Science programme is distinctive in that students complete two different extensive research projects of their choice, allowing them to acquire a wide range of knowledge and skills directly relevant to the study of human disease.
◾If you are aiming to study for a higherBiomedical Science degree , this programme is designed for you.
◾If you want to enter the pharmaceutical and biotechnology industries, this programme provides excellent training; and is an ideal introduction for overseas students who may wish to proceed to PhD biomedical science studies in the UK.
◾You can choose to specialise within a particular discipline or area, which can be important for career development, see programme structure below for more information.

Programme structure

The overall aims of the programme are:
◾to provide students with the knowledge, skills and confidence needed to pursue a career in laboratory research.
◾to provide students with a theoretical and practical understanding of advanced techniques used in modern biomedical sciences research.
◾to provide students with the opportunity to practice research skills in the laboratory by completing two extensive research projects.

MRes students have the opportunity to specialise in a particular discipline or area, which can be important for their career development. The specialisations are:
◾Biotechnology
◾Cancer Studies
◾Cardiovascular Studies
◾Cell Engineering
◾Integrative Mammalian Biology SFC funded places available

◾Medical Biochemistry and Molecular Biology
◾Molecular Genetics
◾Neuroscience
◾Proteomics

To qualify for a specialisation, students must select two research projects in a cognate research area.

Research projects

The central and most important part of the MRes is the two research projects that students undertake. Students choose both projects themselves in the subject areas that interest them and that will allow them to follow the career path they wish to follow. The MRes programme has a huge number of projects which students can choose from, across a wide spectrum of biomedical science.

The following are examples of the types of projects offered, to illustrate the range of subject areas.

• Making blood from human embryonic stem cells

• A gene-microarray based approach to the detection of recombinant human erythropoietin doping in endurance athletes

• Neuropathology of trypanosomiasis

• Development of a new technique for stem cell transfection

• Cloning and analysis of an inflammatory factor in cancer and autoimmune disease

• Analysis of viral induced cancer

Each year students have about 100 different projects to choose from and all students find research topics that interest them.

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Your programme of study. Genetics at University of Aberdeen is taught at the heart of a very large teaching hospital at Foresterhill. Read more

Your programme of study

Genetics at University of Aberdeen is taught at the heart of a very large teaching hospital at Foresterhill. This gives you access to experts within a wide variety of areas including bioinformatics, mendelian genetics, applied statistics and immunogenetics. The MSc degree in Genetics will take you through a wide-ranging curriculum describing some of the latest advances in genetics. You understand how diversity influences clinical outcomes, transplants, infections, autoimmune disease, cancer, immunodeficiency and human reproduction. We have the best support services in the UK to ensure you have guidance from the start.

Graduates from this programme can go on to work in hospital and research laboratories, projects at national and international level to understand health issues, training, scientific publishing, civil service, regulatory areas, government agencies and as consultants to regulators.

Courses listed for the programme

Semester 1

  • Compulsory
  • Bioinformatics
  • Applied Statistics
  • Generic Skills
  • Basic Skills - Induction
  • Introduction to Molecular Biology

Optional

  • Introductory Immunology
  • Introduction to Microbiology

Semester 2

  • Genome - Enabled Medicine
  • Research Tutorials
  • Immunogenetics
  • Mendelian Genetics

Semester 3

  • Masters Research Project

Find out more detail by visiting the programme web page

Why study at Aberdeen?

  • You are taught by leading genetics and bioscience researchers with immunogenetics unique to Aberdeen
  • You have access to a large teaching hospital with dynamic research culture
  • Researchers at Aberdeen invented insulin treatment winning the Nobel Prize

Where you study

  • University of Aberdeen
  • Full Time or Part Time
  • 12 months or 24 months
  • September start

International Student Fees 2017/2018

Find out about fees

*Please be advised that some programmes have different tuition fees from those listed above and that some programmes also have additional costs.

Scholarships

View all funding options on our funding database via the programme page

Living in Aberdeen

Find out more about:

  • Your Accommodation
  • Campus Facilities
  • Aberdeen City
  • Student Support
  • Clubs and Societies

Find out more about living in Aberdeen and living costs



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Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research. Read more

Understanding the molecular basis of disease

Aspiring to contribute to the development of new therapies for metabolic, infectious and immunological diseases or cancer? Radboud University's internationally acclaimed Research Master's programme in Molecular Mechanisms of Disease provides an excellent foundation for a career in academic or commercial research.

Only by dissecting the molecular mechanisms that trigger and advance diseases and dysfunctions can we design effective treatments and medicines. The Research Master's in Molecular Mechanisms of Disease (MMD) offers you an intensive two-year programme that provides you with in-depth knowledge and research experience of disease-related molecular mechanisms. In addition, you will acquire skills such as academic writing and presentation skills and learn how to successfully apply for grants and market yourself.

Passion for molecular biomedical research

As an MMD student you will be part of the unique research community that is found within the Radboud Institute for Molecular Life Sciences (RIMLS). Like you, RIMLS researchers have a strong passion for research. They will assist you throughout the programme with guidance and expertise, supporting you in acquiring knowledge and developing excellent research skills. The RIMLS is one of the research institutes of the Radboud university medical center, so their research is closely linked to the clinic and thus aimed at translating results into treatments for patients. Examples include the translation of insights into the biology of antigen-presenting cells into new immunological cancer therapies and understanding the mutations underlying blindness into the development of gene therapies for patients with inherited blindness.

See the website http://www.ru.nl/masters/mmd

Why study Molecular Mechanisms of Disease at Radboud University?

- You will follow a broad biomedical programme that allows you to specialise in your specific field-of-interest.
- You will have intense daily contact with established researchers.
- You will participate in group-oriented education and be part of a small group of highly motivated national and international students.
- A personal mentor will help you to reflect on your study programme and career perspective.
- You will do two 6-months research internships one of which will be abroad.
- There is a 92% pass rate of MMD students within the two years.
- International MMD students can apply for scholarships from the Radboudumc Study Fund.

Career prospects

There is considerable demand for experts in the molecular biomedical sciences as well as in their application to the development of treatments for diseases such as cancer, autoimmune and inflammatory disorders, and metabolic diseases.

Graduates in MMD are equipped with cutting-edge knowledge of multidisciplinary research in the mechanisms of disease and in state-of-the-art diagnostic methods and technologies. During the programme, you will develop a highly critical, independent approach to problem-solving. You will also acquire the basic management skills needed to lead R&D projects in the biotechnology and pharmaceutical industries.

Most of our graduates will enter an international PhD programme to continue with research in academia or industry.

PhD opportunities

The MSc Molecular Mechanisms of Disease aims to provide all skills and knowledge necessary to rapidly enter an international PhD programme. In the Netherlands and many places in Europe, it is impossible to start a PhD programme directly after obtaining a Bachelor's degree. This research Master’s programme seriously increases your chances for obtaining an excellent PhD training position by giving you a mature perspective and a broad range of experimental approaches. In fact, over 90% of our graduates has started a (funded) PhD project.

The Radboud Institute for Molecular Life Sciences (RIMLS) recruits about fifty PhD students a year. MMD graduates are excellent candidates for these positions. Furthermore, the Radboud university medical centre offers the opportunity for its research-oriented Master's students to write their own research project. The best candidates are awarded a fully funded four-year PhD studentship at the department of their choice.

Our approach to this field

The molecular regulation of cellular processes is crucial for human development, and maintenance of health throughout life. It's evident that cellular malfunction is the cause of common multi-factorial diseases such as diabetes, immune and inflammatory disorders, renal disease, cardiovascular, metabolic and neurodegenerative diseases as well as obesity and cancer.

The Radboud Institute for Molecular Life Sciences (RIMLS) Graduate School plays a key role in developing new therapies for the fight against such diseases. RIMLS aims to improve diagnostics and develop new treatments by generating basic knowledge in the molecular biomedical life sciences and translating it into clinical application and experimental research in patients.

The RIMLS – which is part of Radboud university medical center – offers an exclusive Master's programme in Molecular Mechanisms of Disease. Top researchers and clinicians teach the programme.

Key themes

The MMD programme is organised along three major educational themes which reflect the main research areas present in the RIMLS and which each include both a fundamental and a disease-related aspect:
- Theme 1 Infection, Immunity and Regenerative Medicine / Immunity-related Disorders and Immunotherapy
- Theme 2 Metabolism, Transport and Motion / Metabolic Disorders
- Theme 3 Cell Growth and Differentiation / Developmental Disorders and Malignancies

See the website http://www.ru.nl/masters/mmd

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The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Read more
The Institute of Genetic Medicine brings together a strong team with an interest in clinical and developmental genetics. Our research focuses on the causes of genetic disease at the molecular and cellular level and its treatment. Research areas include: genetic medicine, developmental genetics, neuromuscular and neurological genetics, mitochondrial genetics and cardiovascular genetics.

As a research postgraduate in the Institute of Genetic Medicine you will be a member of our thriving research community. The Institute is located in Newcastle’s Life Science Centre. You will work alongside a number of research, clinical and educational organisations, including the Northern Genetics Service.

We offer supervision for MPhil in the following research areas:

Cancer genetics and genome instability

Our research includes:
-A major clinical trial for chemoprevention of colon cancer
-Genetic analyses of neuroblastoma susceptibility
-Research into Wilms Tumour (a childhood kidney cancer)
-Studies on cell cycle regulation and genome instability

Cardiovascular genetics and development

We use techniques of high-throughput genetic analyses to identify mechanisms where genetic variability between individuals contributes to the risk of developing cardiovascular disease. We also use mouse, zebrafish and stem cell models to understand the ways in which particular gene families' genetic and environmental factors are involved in the normal and abnormal development of the heart and blood vessels.

Complex disease and quantitative genetics

We work on large-scale studies into the genetic basis of common diseases with complex genetic causes, for example autoimmune disease, complex cardiovascular traits and renal disorders. We are also developing novel statistical methods and tools for analysing this genetic data.

Developmental genetics

We study genes known (or suspected to be) involved in malformations found in newborn babies. These include genes involved in normal and abnormal development of the face, brain, heart, muscle and kidney system. Our research includes the use of knockout mice and zebrafish as laboratory models.

Gene expression and regulation in normal development and disease

We research how gene expression is controlled during development and misregulated in diseases, including the roles of transcription factors, RNA binding proteins and the signalling pathways that control these. We conduct studies of early human brain development, including gene expression analysis, primary cell culture models, and 3D visualisation and modelling.

Genetics of neurological disorders

Our research includes:
-The identification of genes that in isolation can cause neurological disorders
-Molecular mechanisms and treatment of neurometabolic disease
-Complex genetics of common neurological disorders including Parkinson's disease and Alzheimer's disease
-The genetics of epilepsy

Kidney genetics and development

Kidney research focuses on:
-Atypical haemolytic uraemic syndrome (aHUS)
-Vesicoureteric reflux (VUR)
-Cystic renal disease
-Nephrolithiasis to study renal genetics

The discovery that aHUS is a disease of complement dysregulation has led to a specific interest in complement genetics.

Mitochondrial disease

Our research includes:
-Investigation of the role of mitochondria in human disease
-Nuclear-mitochondrial interactions in disease
-The inheritance of mitochondrial DNA heteroplasmy
-Mitochondrial function in stem cells

Neuromuscular genetics

The Neuromuscular Research Group has a series of basic research programmes looking at the function of novel muscle proteins and their roles in pathogenesis. Recently developed translational research programmes are seeking therapeutic targets for various muscle diseases.

Stem cell biology

We research human embryonic stem (ES) cells, germline stem cells and somatic stem cells. ES cell research is aimed at understanding stem cell pluripotency, self-renewal, survival and epigenetic control of differentiation and development. This includes the functional analysis of genes involved in germline stem cell proliferation and differentiation. Somatic stem cell projects include programmes on umbilical cord blood stem cells, haematopoietic progenitors, and limbal stem cells.

Pharmacy

Our new School of Pharmacy has scientists and clinicians working together on all aspects of pharmaceutical sciences and clinical pharmacy.

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This well-established and highly competitive MSc provides students with specialist training in the basic scientific principles of modern neuroscience, and in the application of these principles to the understanding of a wide variety of neurological disorders. Read more
This well-established and highly competitive MSc provides students with specialist training in the basic scientific principles of modern neuroscience, and in the application of these principles to the understanding of a wide variety of neurological disorders. Students benefit from studying in an internationally renowned and research-intensive environment at the UCL Institute of Neurology.

Degree information

Participants gain knowledge of the clinical features and scientific basis of both common and unusual neurological disorders including a study of: genetics of CNS disorders; brain metabolism, neurotransmitters and neurodegeneration; autoimmune disease and repair mechanisms; peripheral nerve and muscle; epilepsy; nociception and pain; motor control; basal ganglia/movement disorders; hearing, balance, vision and eye-movements; stroke and head injury; cognition and dementia.

Students undertake modules to the value of 180 credits.

The programme consists of six core modules (90 credits), a library project (30 credits) and a research project (60 credits). There are no optional modules for this programme.

Core modules
-Cellular and Molecular Mechanisms of Disease
-Diseases of the Nervous System: Epilepsy, Pain, Tumours & Infection
-Peripheral Nerve, Muscle and Special Senses
-Motor Systems and Disease
-Higher Functions of the Brain
-Research Methods: Critical Appraisal and Introduction to Statistics

Dissertation/report
All students undertake a library project which is assessed by a 5,000-word essay, and an independent research project, which culminates in a dissertation of 10,000 words.

Teaching and learning
The programme is delivered through basic and clinical lectures, seminars and practical and interactive workshops. Lectures are supported by audio-visual aids and supplementary materials including handouts, reading lists and references to original papers. Assessment is through unseen and multiple-choice examination, essay, library project, dissertation and oral examination.

Careers

This programme offers an established entry route into both PhD studies in the UK and internationally, and to medicine at both undergraduate and graduate level.

Top career destinations for this degree:
-Research Assistant, Duke-NUS
-Research Assistant, UCL
-MBBS in Medicine, Barts Health NHS Trust and The London School of Medicine and Dentistry
-PhD in Clinical Medicine, University of Oxford
-PhD in Clinical Neuroscience, University College London (UCL)

Employability
Students are given the opportunity to take an original research project in a world-renowned centre of excellence. Publications routinely result from the best MSc projects.

Why study this degree at UCL?

The mission of the UCL Institute of Neurology is to carry out high-quality research, teaching and training in basic and clinical neurosciences. Together with our associated hospital, the National Hospital for Neurology and Neurosurgery, the institute promotes the translation of research that is of direct clinical relevance to improved patient care and treatment.

With its concentration of clinical and applied scientific activity the institute is a unique national resource for postgraduate training in neuroscience, and this MSc enhances the scientific skills of clinicians and provides non-clinical graduates with insight into clinical problems that will allow them to work alongside clinicians in clinical research projects.

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The MSc in Molecular Medicine gives you the opportunity to develop as a scientist or scientifically-literate clinician through an advanced understanding of the molecular basis of many diseases and their treatments. Read more

The MSc in Molecular Medicine gives you the opportunity to develop as a scientist or scientifically-literate clinician through an advanced understanding of the molecular basis of many diseases and their treatments.

You’ll study how to apply molecular approaches to the diagnosis, prevention and treatment of a range of cancers, chronic, autoimmune and genetic diseases. You’ll also carry out a research project in one of these areas within a research group at the forefront of the field. Project supervision is assured by outstanding academics and clinicians working on cutting-edge research.

This flexible programme allows you to develop core scientific skills and follow your professional interests with a choice of optional modules. You'll be part of a world-renowned School and will be taught by internationally recognised scholars.

The MSc programme comprises 180 credits. You may choose to exit the programme at an earlier stage, with either a PG Certificate (60 credits) or a PG Diploma (120 credits).

Course content

You’ll build core scientific skills through four compulsory modules studied over two terms. Alongside these, your optional modules (two each term) allow you to tailor your study to your interests. Modules typically last 11 weeks.

Throughout the programme you will:

  • gain an in-depth knowledge and understanding of the principles, application and potential of molecular medicine
  • learn techniques in the field of molecular biology, immunology, cell biology and chemistry
  • develop the ability to carry out molecular, biological and bioinformatics research for investigation of human diseases
  • be able to engage in research projects using the latest technologies that generate results with scientific impact and the potential for improving patient health
  • learn to critically evaluate current issues in molecular medicine, translate research findings into clinical applications, and recognise commercial opportunities.

Research project

You’ll spend approximately half of the programme on your individual research project, which usually runs from April to August. The research project allows you to work as part of a research team in a cutting edge discipline.

You will have a wide choice of research opportunities in Applied Health Research, Cancer and Pathology, Cardiovascular, Genes and Development and Musculoskeletal Research. You select your project from a range of research projects offered to MSc Molecular Medicine students.

The research project is based in one of the research laboratories at the St James’s University Hospital campus.

Course structure

Compulsory modules

  • Research Informatics and Dissemination 15 credits
  • Preparing for the Research Project 15 credits
  • Research Project 75 credits
  • Research Methods 15 credits

Optional modules

  • Introduction to Genetic Epidemiology 15 credits
  • Human Molecular Genetics 15 credits
  • Immunity and Disease 15 credits
  • Animal Models of Disease 15 credits
  • Stem Cell Biology: A Genomics and Systems Biology Approach to Haematopoiesis 15 credits
  • Cancer Biology and Molecular Oncology 15 credits

For more information on typical modules, read Molecular Medicine MSc in the course catalogue

Learning and teaching

The taught components of the programme provide a perfect knowledge background and research training to get the best out of your research project.

You’ll be taught by active scientists and clinicians who are world-leading in their research fields, through lectures, workshops, laboratory practicals, seminars and tutorials. All our students judged the programme as “intellectually stimulating” in 2014 student survey.

Teaching is mainly at St James's University Hospital, a busy research facility with research laboratories and a teaching laboratory, computer cluster, library and meeting rooms. You can easily get to and from the University campus with the free NHS shuttlebus.

We encourage you to participate in the School of Medicine Institutes’ activities, such as the invited speaker seminar series. You also have access to all the wider University of Leeds facilities.

Assessment

A major objective of the programme is to train you to formulate your own ideas and express them logically, and this will be tested in every module assessment.

A typical module will be assessed by two assignments. Assessments include written assignments, as well as delivering presentations and posters, and leading discussions.

The MSc programme comprises 180 credits. You may choose to exit the programme at an earlier stage, with either a PG Certificate (60 credits) or a PG Diploma (120 credits).

Career opportunities

This exciting programme provides excellent training for:

  • science graduates looking for an opportunity to go on to do doctoral research, enter academic medicine or pursue a career in industry, clinical service




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This MSc programme in Biomedical Sciences offers research training for student intending to proceed to a career in biomedical sciences, either directly or through a PhD. Read more
This MSc programme in Biomedical Sciences offers research training for student intending to proceed to a career in biomedical sciences, either directly or through a PhD. It is based on a research project and coursework.

Why this programme

◾Ranked world top 100 for Biological Sciences
◾The programme provides training in a wide range of modern molecular biology techniques required to pursue a research career in biomedical science.
◾You will gain valuable practical research experience by using the skills and techniques acquired during the programme to complete an in depth research project.
◾If you are aiming to study for a higher degree, or enter a biomedical career, then this programme is designed specifically for you.
◾If you want to enter the pharmaceutical and biotechnology industries, this programme provides excellent training.
◾It is an ideal introduction for overseas students who may wish to proceed to PhD studies in the UK, Europe or the USA.
◾This course is similar to the MRes Biomedical Sciences, but instead has more teaching in the first part of the programme, and one research project, which starts later in the year. This allows students more time to acquire knowledge and skills before they start their research work.

Programme structure

The overall aims of the programme are:
◾to provide students with the knowledge, skills and confidence needed to pursue a career in laboratory research.
◾to provide students with a theoretical and practical understanding of advanced techniques used in modern biomedical sciences research.
◾to provide students with the opportunity to practice research skills in the laboratory by completing an extensive research project in an area of their choice.

Projects

An important part of the MSc is your choice of research project; there are a huge number of choices available from a wide spectrum of biomedical science. Please see examples below:

• Making blood from human embryonic stem cells

• A gene-microarray based approach to the detection of recombinant human erythropoietin doping in endurance athletes

• Neuropathology of trypanosomiasis

• Development of a new technique for stem cell transfection

• Cloning and analysis of an inflammatory factor in cancer and autoimmune disease

• Analysis of viral induced cancer

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The Faculty of Engineering and Science offers advanced research training opportunities across a broad range of subject areas, including chemical, pharmaceutical, biomedical, environmental and sports sciences. Read more
The Faculty of Engineering and Science offers advanced research training opportunities across a broad range of subject areas, including chemical, pharmaceutical, biomedical, environmental and sports sciences. The research activities within the Department are supported by state of the art analytical and computer facilities.

Upon acceptance to a programme, students normally register initially for an MPhil, and at the end of the first year, the student is examined by viva voce for consideration for transfer to PhD. Upon completion of the Doctoral training, students are ideally equipped to work in an academic or industrial research environment.

Recent research project topics include:

- Solar energy conversion

- Synthesis of biologically active molecules

- Fragment-based drug discovery

- In situ monitoring of chemical reactions

- Treatment of contaminated soils by accelerated carbonation

- Production of novel silicate-based sorbents

- Integrated production of biodiesel from oilseed rape

- Pathogenesis of autoimmune diseases

- Bioremediation and composting technologies

- Expert Cognition and Training

The aims of the programme are:

- To develop, create and interpret new knowledge, through original research or other advanced scholarship, of a quality to satisfy peer review, extend the forefront of the discipline, and merit publication

- To systematically acquire an understanding of a substantial body of knowledge which is at the forefront of an academic discipline or area of professional practice

- To demonstrate the ability to conceptualise, design and implement a project for the generation of new knowledge, applications or understanding at the forefront of the discipline, and to adjust the project design in the light of unforeseen problems

- To show a detailed understanding of applicable techniques for research and advanced academic enquiry.

Visit the website http://www2.gre.ac.uk/study/courses/pg/res/scires

What you'll study

Research areas may include:

- Materials analysis
- Molecular spectroscopy, Advanced spectral analysis
- Biomaterials
- Formulation chemistry, Biophysical chemistry
- Pharmaceutical science
- Gene therapy
- Biochemistry, Cell biology
- Forensic science
- Environmental geochemistry
- Sports science and human performance
- Applied cognitive science

Fees and finance

Your time at university should be enjoyable and rewarding, and it is important that it is not spoilt by unnecessary financial worries. We recommend that you spend time planning your finances, both before coming to university and while you are here. We can offer advice on living costs and budgeting, as well as on awards, allowances and loans.

Find out more about our fees and the support available to you at our:

- Postgraduate finance pages (http://www.gre.ac.uk/finance/pg)
- International students' finance pages (http://www.gre.ac.uk/finance/international)

Assessment

Students are assessed through their thesis and an oral examination.

Career options

Graduates from this programme can pursue careers in industry, government and academia.

Find out how to apply here - http://www2.gre.ac.uk/study/apply

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The course will enable biomedical & clinical students (including research midwives and nurses) to develop an academic and contemporary understanding of the biological and environmental influences that impact on pregnancy and the lifelong physical and mental wellbeing health of women and their infants. Read more

The course will enable biomedical & clinical students (including research midwives and nurses) to develop an academic and contemporary understanding of the biological and environmental influences that impact on pregnancy and the lifelong physical and mental wellbeing health of women and their infants

Students will gain insight and knowledge of how translation of basic science and clinical observation can lead to cutting edge research studies into new diagnostic and treatments both in the UK and in low resource settings globally. .

Students will develop scientific and clinical practical research skills, including statistics, so that they can confidently critically evaluate others research design and results, and apply these to their own research. They will also be given the necessary research knowledge and skills to design, plan, navigate research governance pathways, and conduct and analyse their own research project. Both scientific and clinical research projects are offered. 

Key Benefits

  • Substantial student-tutor contact time
  • Cross disciplinary teaching with a focus on translating research to the clinic and the global community
  • Research project in world class laboratories and research groups in Women’s, Perinatal and Child Health, Paediatric Allergy, Mental Health, Nutrition, Mental and Global Health.
  • Access to the latest leading cutting edge technologies housed at KCL and the NIHR Biomedical Research Centre including next generation sequencing, a range of ‘Omics and neonatal imaging, as well as dedicated clinical research units.
  • Lectures delivered by experienced and internationally recognised researchers and clinicians covering contemporary issues in Womens and Children’s health research 
  • Interactive tutorials and workshops on writing successful research grants, clinical study protocols and ethics applications.
  • The programme offers advanced practical experience and supervised training together with an in-depth research project
  • The programme prepares students for future MD and PhD study

Description

The MSc Women and Children's Health comprises three core taught modules, including ‘Fundamentals of Womens and Children’s Health’ which covers health and disease from the periconception period to birth and early childhood. Research led lectures will cover topics such as infertility, pre-pregnancy health, placentation, preeclampsia; immunology of pregnancy and autoimmune disease, metabolic disease in pregnancy, parturition and dysfunctional labour, miscarriage and preterm birth, lactation and infant nutrition, the developing brain and prematurity, childhood diet and dental health, premature infant and the neonatal lung, gut microbiome, obesity, childhood allergy, epigenetics and lifelong health, nutrition and global health and perinatal mental health.

The other required taught modules are Statistics and Research Governance, and Scientific and Clinical Research skills followed by an intensive six month core research projectwithin a lab or clinical research group.

Students can also select 1-2 optional taught module(s) to tailor the course to their developing interests, examples include Perinatal Mental Health, Ethics in Child Health, Regenerative Medicine, Principles of Implementation and Improvement, Science, Leadership and Management, Birth Defects, Assisted Conception, Regenerative Medicine and Global Women's Health.

The programme fosters intellectual skills of students through:

  • Critical assimilation and appraisal of the research literature pertaining to Womens and Children's Health.
  • Production of original pieces of written work that explain, review and evaluate primary research literature and using this evaluation to develop ideas and hypothesises.
  • Understand research governance and demonstrate compliance with research regulations.
  • Understand and apply scientific and clinical study design and statistical analysis principles.
  • Recognise the moral and ethical issues of investigations and appreciate the need for ethical standards and professional codes of conduct.
  • Think critically about their own work/research and to input into the synthesis and design of future hypotheses and experiments.
  • Use subject knowledge and understanding to explore and solve familiar and unfamiliar problems.
  • Collect, interpret and analyse data with a critical understanding of the appropriate contexts for their use through the study of primary research articles, and the student's own data.

Course format and assessment

Teaching

A typical week would be have approximately 10-15 hours teaching with the remaining hours dedicated to self-guided learning. In the final semester, research projects are full time with hours dedicated to practical and data collection, data analysis and writing.

You will study via a combination of lectures, journal clubs, group discussions, practicals, workshops and independent study.

Peer feedback, in course assignments such as data handling, research project and project report write-up, journal club, presentations and essays. All will be actively encouraged throughout the research project.

Typically, one credit equates to 10 hours of work.

Assessment

We will assess you through a combination of coursework, seen/unseen written exams, essays, problem directed learning exercises, case studies, ethical problem debate, data-handling, creation of clinical study materials such as patient information sheets and consent forms, research proposal, oral presentations, and a final research project report.

The study time and assessment methods detailed above are typical and give you a good indication of what to expect. However, they may change if the course modules change.

Career prospects

The course will prepare scientists and clinicians for further research into Womens & Children’s Health



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