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Masters Degrees (Adme)

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This course is designed for graduates of chemistry, pharmacy and other related sciences who are contemplating a career in the pharmaceutical industry, academia, the NHS or with government agencies such as drug licensing authorities. Read more
This course is designed for graduates of chemistry, pharmacy and other related sciences who are contemplating a career in the pharmaceutical industry, academia, the NHS or with government agencies such as drug licensing authorities.

The programme provides a good background in basic pharmaceutical sciences followed by advanced training in drug discovery, drug product design, drug delivery, pharmacology, microbiology and regulatory processes. It also offers advanced practical experience and supervised training, together with an opportunity to undertake an in-depth research project as part of an active research group.

This course is suitable for both UK and non-UK graduates, and international students benefit from our excellent support networks.

Scholarships

Scholarships are available for this course. Please click the link below for more information.
https://www.brighton.ac.uk/studying-here/fees-and-finance/postgraduate/index.aspx

Course structure

This course is one calendar year, full-time, involving 30 weeks of taught modules divided into two 15-week semesters, and a project which is largely carried out during the remaining time.

Students may have the opportunity to undertake a short industrial placement (optional) during their second semester. A four-month research project is integrated into the second semester, on completion of which you will be required to submit a 10,000 word dissertation. The assessment of each taught module includes coursework and a written examination paper at the end of semester two.

Past research project topics include the development of novel transdermal formulations containing naturally occurring antioxidants as sunscreen agents, and the use of mucoadhesive gels for vaginal drug delivery.

Syllabus

During the course you will:

• develop knowledge and understanding of the role of drug discovery; biological processes involved in drug action; drug product design; quality assurance, quality control and regulatory affairs
• develop knowledge and understanding of the chemical principles underlying the design, action and disposition of drug molecules
• appreciate aspects of drug ADME and the underlying mathematical principles, mechanisms of action and adverse effects of drug treatments and the phenomenon of drug interactions
• develop an understanding of the microbiological processes involved in the development and quality assurance of non-sterile and sterile medicines and devices including biotechnology products
• develop knowledge and understanding of the basic principles and current trends in the formulation design and manufacture of pharmaceutical dosage forms
• deveop an appreciation of the physicochemical and biological factors which affect uniformity, performance, stability and bioavailability of pharmaceutical products.

Modules:

Research Project
Research Methods
Pharmacology and Drug Development
Regulatory Affairs
Industrial Pharmacy, QA and QC
Current Research in Pharmacy and Pharmacology

Options:

Industrial Placement
Advanced Pharmaceutical Analysis
Advanced in Biochemical and Clinical Analysis
Quality Issues in Complementary Therapies That Utilise Plants
New Medicinal Products: From Inception to Market
Industrial Manufacturing Processes
Advanced Drug Delivery

Careers and Employability

This course will equip you for a career in the pharmaceutical industry, NHS, academic centres, research institutions or with government agencies such as drug licensing authorities. Our graduates are also well placed to apply for a PhD.

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A master's in Clinical Pharmacology will enable you to gain the knowledge and skills to evaluate the safety of new medicinal products for human studies, write a clinical protocol, and obtain appropriate ethical and legal approval. Read more
A master's in Clinical Pharmacology will enable you to gain the knowledge and skills to evaluate the safety of new medicinal products for human studies, write a clinical protocol, and obtain appropriate ethical and legal approval. One of three modular programmes in Pharmaceutical Medicine designed for working physicians, clinical scientists and allied health professionals interested in the clinical development process.

Key benefits

- King's is ranked 4th in the world for Pharmacy & Pharmacology (QS World University Rankings by Subject 2016)

- Flexible programmes with a part-time option that allows you to fit the modules in with your work schedule.

- Teaching given by leading experts from the academic staff of King’s College London, from the biopharmaceutical sector and the regulatory authorities.

Visit the website: http://www.kcl.ac.uk/study/postgraduate/taught-courses/clinical-pharmacology-msc-pg-dip-pg-cert.aspx

Course detail

- Description -

Pharmaceutical Medicine is the medical scientific discipline concerned with the discovery, development, evaluation, registration, monitoring and medical aspects of the marketing of medicines for the benefit of patients and the health of the community.

In this rapidly expanding field of medicine there is a need for high quality education programmes that are compliant with the PharmaTrain initiative of the European Commission, but also with the Bologna process. The programmes at King’s will be the first in the UK that meet both of these requirements. This, plus the opportunity to study at a world class university makes King’s the ideal place at which to study for one of these MSc subjects.

Clinical Pharmacology is the study of how drugs influence human physiology and the way the body handles drugs. It is a vital part of the early clinical development of new medicines. It requires an understanding of preclinical science, ethical and legal requirements for clinical research programmes and how to design and interpret individual clinical trials. A well designed clinical pharmacology programme informs the final regulatory of a new medicine. Generating skilled clinical pharmacologists is therefore vital to ensure that new medicines are efficiently developed.

- Format and assessment -

Each taught module is delivered as a distinct intensive four or five day taught course, accompanied by distance learning and written assessments.

Core modules:

- ADME, Pharmacokinetics & Pharmacodynamics
- Advanced Clinical Pharmacology
- Clinical Drug Development
- Clinical Pharmacology Research Project
- Drug Development Pharmacology
- Exploratory Drug Development
- Practical Clinical Pharmacology

3 assignments plus 1 online multiple choice test for each module.

- Course purpose -

This programme is for those working in or seeking to work in the field of clinical drug development. It covers all aspects of the clinical development process through from the earliest studies to post marketing activities. It will enhance knowledge and skills in all aspects of clinical research, drug regulation and drug safety.

Career prospects

It is expected that students who complete this programme will be able to work in the clinical research arena at a higher level and this will open up job opportunities that might have previously been beyond their reach and enhance their value to their employers.

How to apply: http://www.kcl.ac.uk/study/postgraduate/apply/taught-courses.aspx

About Postgraduate Study at King’s College London:

To study for a postgraduate degree at King’s College London is to study at the city’s most central university and at one of the top 20 universities worldwide (2015/16 QS World Rankings). Graduates will benefit from close connections with the UK’s professional, political, legal, commercial, scientific and cultural life, while the excellent reputation of our MA and MRes programmes ensures our postgraduate alumni are highly sought after by some of the world’s most prestigious employers. We provide graduates with skills that are highly valued in business, government, academia and the professions.

Scholarships & Funding:

All current PGT offer-holders and new PGT applicants are welcome to apply for the scholarships. For more information and to learn how to apply visit: http://www.kcl.ac.uk/study/pg/funding/sources

Free language tuition with the Modern Language Centre:

If you are studying for any postgraduate taught degree at King’s you can take a module from a choice of over 25 languages without any additional cost. Visit: http://www.kcl.ac.uk/mlc

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Our MSc Model-based Drug Development course provides the knowledge and skills for making evidence-based decisions at various stages of drug development. Read more
Our MSc Model-based Drug Development course provides the knowledge and skills for making evidence-based decisions at various stages of drug development.

It covers the scientific and regulatory aspects of evaluating a drug, with emphasis on the use of modelling and simulation methods. You will learn why these methods are so highly valued by industry and regulatory authorities as effective, cost-saving, decision-making tools. Learning is reinforced via hands-on application of the skills to real data.

The course has been developed with an emphasis on mechanistic approaches to assessing and predicting pharmacokinetics and pharmacodynamics (PKPD), such as physiologically-based pharmacokinetics (PBPK).

As this comes under the general umbrella of systems biology, you will be able to apply your knowledge of modelling and simulation in various areas of research within the pharmaceutical industry.

Full-time students benefit from immersion in the varied biomedical research environment at The University of Manchester, including interaction with research staff at the renowned Centre for Applied Pharmacokinetic Research.

Alternatively, part-time students already working in the pharmaceutical industry can take advantage of the flexible, distance learning mode of the course, which allows you to fit study around other commitments.

Aims

The aim of the course is to provide specialist knowledge and skills that are highly relevant for a career linked to drug development and pharmaceutical industry.

It is designed for science, engineering or mathematics graduates who want to acquire:
-Awareness of the commercial and regulatory factors in drug development
-Understanding of the physiological, chemical, and mathematical foundations used to define the safe and effective use of potential medicines
-Training in the use of mathematical modelling and simulation methods to guide drug development

The course aims to:
-Provide background information on the theory and methods for quantitative assessment of drug absorption, distribution and elimination
-Provide an understanding of the role of pharmacometrics in the process of drug development
-Provide background information on in vitro assays used to characterise ADME properties of new drug entities
-Indicate the mathematical framework that is capable of integrating in vitro information with knowledge of the human body to predict pharmacokinetics
-Provide familiarity and experience of using different software platforms related to pharmacometric data analysis including R, Phoenix, NONMEM, MATLAB, Simcyp, WinBUGS and MONOLIX
-Equip you to reflect upon influential research publications in the field, to critically assess recent published literature in a specific area
-Provide awareness of the elements of a convincing research proposal based on modelling and simulation
-Provide the opportunity to undertake a project and carry out original research

Teaching and learning

The course emphasises the development of problem-solving skills. A large portion of the learning involves structured problems requiring the you to apply theory and practical skills to solve typical problems that arise in drug development.

The following teaching and learning methods are used throughout the course:
-Taught lectures
-Hands-on workshops
-Self-directed learning to solve given problems
-Webinars and tutorials by leading scientists in industry/academia
-Supervised research
-Mentorship in solving problems and writing the research dissertation
-Independent study

Career opportunities

This course was originally developed for scientists working within the pharmaceutical industry who wished to qualify as modellers with hands-on experience. The qualification will enhance your abilities within your current role or provide you with skills to progress into new posts.

The course is also appropriate for science and engineering graduates who wish to enter the industry. The role of modelling and simulation or pharmacometrics is assuming greater and greater importance in the pharmaceutical industry. Pharmaceutical companies and government regulatory agencies are recognising its value in making best use of laboratory and clinical data, guiding and expediting development, saving time and costs and a range of well paid jobs exist in this area across the globe. Scientific and industry publications often discuss the current shortage and growing need for modellers.

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